Symbol:
KLK4
Name:
kallikrein related peptidase 4
RGD ID:
12117701
Description:
ENCODES a protein that exhibits hydrolase activity (inferred); peptidase activity (inferred); serine-type endopeptidase activity (inferred); INVOLVED IN amelogenesis (ortholog); extracellular matrix disassembly (ortholog); protein catabolic process (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); amelogenesis imperfecta type 2A1 (ortholog); breast cancer (ortholog)
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
kallikrein-4
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
KLK4 (kallikrein related peptidase 4) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Treefam
Mus musculus (house mouse):
Klk4 (kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):
Klk4 (kallikrein-related peptidase 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
KLK4 (kallikrein related peptidase 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Klk4 (kallikrein related peptidase 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
KLK4 (kallikrein related peptidase 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):
KLK4 (kallikrein related peptidase 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Klk4 (kallikrein related peptidase 4) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Other homologs 2
Homo sapiens (human):
KLK15 (kallikrein related peptidase 15) HGNC
OrthoDB
Latest Assembly:
CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 1 105,950,948 - 105,955,464 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 1 105,951,691 - 106,007,581 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 1 105,526,312 - 105,529,783 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 1 106,462,891 - 106,466,451 (+) NCBI ROS_Cfam_1.0 UMICH_Zoey_3.1 1 106,134,079 - 106,137,554 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 1 105,775,605 - 105,779,075 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 1 106,571,164 - 106,574,633 (+) NCBI UU_Cfam_GSD_1.0
JBrowse:
View Region in Genome Browser (JBrowse)
Model
KLK4 Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 1 105,950,948 - 105,955,464 (+) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 1 105,951,691 - 106,007,581 (+) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 1 105,526,312 - 105,529,783 (+) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 1 106,462,891 - 106,466,451 (+) NCBI ROS_Cfam_1.0 UMICH_Zoey_3.1 1 106,134,079 - 106,137,554 (+) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 1 105,775,605 - 105,779,075 (+) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 1 106,571,164 - 106,574,633 (+) NCBI UU_Cfam_GSD_1.0
KLK4 Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 19 50,906,351 - 50,911,395 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 19 50,906,351 - 50,911,395 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 19 51,409,607 - 51,414,651 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 19 56,101,420 - 56,105,806 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Build 34 19 56,101,419 - 56,105,806 NCBI Celera 19 48,460,680 - 48,464,998 (-) NCBI Celera Cytogenetic Map 19 q13.41 NCBI HuRef 19 47,742,948 - 47,747,264 (-) NCBI HuRef CHM1_1 19 51,411,402 - 51,415,787 (-) NCBI CHM1_1 T2T-CHM13v2.0 19 53,994,435 - 53,999,407 (-) NCBI T2T-CHM13v2.0
Klk4 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 7 43,530,584 - 43,535,228 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 7 43,530,584 - 43,535,228 (+) Ensembl GRCm39 Ensembl GRCm38 7 43,881,160 - 43,885,804 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 7 43,881,160 - 43,885,804 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 7 51,136,542 - 51,141,174 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 MGSCv36 7 43,749,214 - 43,753,846 (+) NCBI MGSCv36 mm8 Celera 7 39,349,912 - 39,354,544 (+) NCBI Celera Cytogenetic Map 7 B3 NCBI cM Map 7 28.35 NCBI
Klk4 Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 103,480,731 - 103,485,963 (+) NCBI GRCr8 mRatBN7.2 1 94,344,195 - 94,349,425 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 94,344,195 - 94,349,424 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 1 99,730,033 - 99,734,406 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 108,202,660 - 108,207,031 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 101,492,287 - 101,496,632 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 99,828,944 - 99,834,642 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 99,829,351 - 99,834,216 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 1 100,897,206 - 100,902,435 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 1 94,321,663 - 94,327,488 (+) NCBI RGSC3.4 RGSC_v3.4 rn4 RGSC3.4 RGSC_v3.1 1 94,399,773 - 94,405,599 (+) NCBI Celera 1 88,612,777 - 88,617,038 (+) NCBI Celera Cytogenetic Map 1 q22 NCBI
KLK4 Bonobo Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl NHGRI_mPanPan1-v2 20 56,976,183 - 56,980,802 (-) NCBI NHGRI_mPanPan1-v2 NHGRI_mPanPan1 19 58,896,711 - 58,901,306 (-) NCBI NHGRI_mPanPan1 Mhudiblu_PPA_v0 19 47,849,158 - 47,876,522 (-) NCBI Mhudiblu_PPA_v0 Mhudiblu_PPA_v0 panPan3 PanPan1.1 19 56,739,394 - 56,768,169 (-) NCBI panpan1.1 PanPan1.1 panPan2 PanPan1.1 Ensembl 19 56,764,073 - 56,768,169 (-) Ensembl panpan1.1 panPan2
Klk4
KLK4 Pig Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Sscrofa11.1 Ensembl 6 55,589,999 - 55,594,294 (-) Ensembl Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa11.1 6 55,589,997 - 55,617,514 (-) NCBI Sscrofa11.1 Sscrofa11.1 susScr11 Sscrofa11.1 Sscrofa10.2 6 51,488,847 - 51,498,931 (-) NCBI Sscrofa10.2 Sscrofa10.2 susScr3
KLK4 Green Monkey Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl ChlSab1.1 6 43,921,920 - 43,935,224 (-) NCBI ChlSab1.1 ChlSab1.1 chlSab2 ChlSab1.1 Ensembl 6 43,922,052 - 43,934,253 (-) Ensembl ChlSab1.1 ChlSab1.1 Ensembl chlSab2 Vero_WHO_p1.0 NW_023666073 23,952,102 - 23,956,462 (-) NCBI Vero_WHO_p1.0 Vero_WHO_p1.0
Klk4
.
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
6
5
5
23
22
16
6
6
6
6
33
22
12
14
10
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENSCAFT00000004649 ⟹ ENSCAFP00000004303
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 1 105,951,691 - 105,955,460 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000065092 ⟹ ENSCAFP00000055766
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 1 105,951,691 - 106,007,357 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000082967 ⟹ ENSCAFP00000046015
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 1 105,951,935 - 105,955,027 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000085716 ⟹ ENSCAFP00000052647
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 1 105,951,691 - 105,954,360 (+) Ensembl
Ensembl Acc Id:
ENSCAFT00000089378 ⟹ ENSCAFP00000049439
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 Ensembl 1 106,002,789 - 106,007,581 (+) Ensembl
RefSeq Acc Id:
NM_001197169 ⟹ NP_001184098
RefSeq Status:
VALIDATED
Type:
CODING
Position:
Dog Assembly Chr Position (strand) Source CanFam3.1 1 105,951,702 - 105,955,175 (+) NCBI Dog10K_Boxer_Tasha 1 105,526,312 - 105,529,783 (+) NCBI ROS_Cfam_1.0 1 106,462,891 - 106,466,451 (+) NCBI UMICH_Zoey_3.1 1 106,134,079 - 106,137,554 (+) NCBI UNSW_CanFamBas_1.0 1 105,775,605 - 105,779,075 (+) NCBI UU_Cfam_GSD_1.0 1 106,571,164 - 106,574,633 (+) NCBI
Sequence:
ATGACCACAGCAGGAAGCCCCTGGGGCTGTTTCCTGGGGTACCTCATCCTTGGTGTCACAGGATCCCTGGCCTCGGGTGGCGGCAGCCACATCATCAACGGCGAGGACTGCAGCCCGCACTCACAGCC
hide sequence
RefSeq Acc Id:
NP_001184098 ⟸ NM_001197169
- Peptide Label:
precursor
- UniProtKB:
E2FGH4 (UniProtKB/TrEMBL), A0A8C0YUV4 (UniProtKB/TrEMBL), F1Q0C3 (UniProtKB/TrEMBL), A0A8C0L4G7 (UniProtKB/TrEMBL), A0A1R3UCN4 (UniProtKB/TrEMBL)
- Sequence:
MTTAGSPWGCFLGYLILGVTGSLASGGGSHIINGEDCSPHSQPWQAALFTEDEFFCGGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEPNQEPGSRMMETDLSIQHPEYNKPFVANDLMLIKLKESVSE
hide sequence
Ensembl Acc Id:
ENSCAFP00000004303 ⟸ ENSCAFT00000004649
Ensembl Acc Id:
ENSCAFP00000046015 ⟸ ENSCAFT00000082967
Ensembl Acc Id:
ENSCAFP00000055766 ⟸ ENSCAFT00000065092
Ensembl Acc Id:
ENSCAFP00000049439 ⟸ ENSCAFT00000089378
Ensembl Acc Id:
ENSCAFP00000052647 ⟸ ENSCAFT00000085716
