YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta) - Rat Genome Database

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Gene: YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta) Pan paniscus
Analyze
Symbol: YWHAH
Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
RGD ID: 12049770
Description: ENCODES a protein that exhibits actin binding (inferred); enzyme binding (inferred); identical protein binding (inferred); INVOLVED IN intracellular protein transport (ortholog); negative regulation of dendrite morphogenesis (ortholog); regulation of sodium ion transmembrane transporter activity (ortholog); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; mTOR signaling pathway; phosphatidylinositol 3-kinase-Akt signaling pathway; ASSOCIATED WITH cardiomyopathy (ortholog); Experimental Diabetes Mellitus (ortholog); familial focal epilepsy with variable foci 1 (ortholog); FOUND IN cerebellar granule cell to Purkinje cell synapse (ortholog); glutamatergic synapse (ortholog); presynapse (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: 14-3-3 protein eta; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22341,896,667 - 41,909,802 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12244,597,258 - 44,610,288 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02212,966,653 - 12,979,695 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12230,814,699 - 30,832,613 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2230,819,821 - 30,831,804 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
YWHAH
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22341,896,667 - 41,909,802 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12244,597,258 - 44,610,288 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02212,966,653 - 12,979,695 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12230,814,699 - 30,832,613 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2230,819,821 - 30,831,804 (+)Ensemblpanpan1.1panPan2
YWHAH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382231,944,535 - 31,957,603 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2231,944,522 - 31,957,603 (+)EnsemblGRCh38hg38GRCh38
GRCh372232,340,521 - 32,353,590 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362230,670,479 - 30,683,590 (+)NCBINCBI36Build 36hg18NCBI36
Build 342230,665,082 - 30,678,143NCBI
Celera2216,140,927 - 16,154,032 (+)NCBICelera
Cytogenetic Map22q12.3NCBI
HuRef2215,296,794 - 15,309,903 (+)NCBIHuRef
CHM1_12232,299,883 - 32,312,993 (+)NCBICHM1_1
T2T-CHM13v2.02232,408,656 - 32,421,713 (+)NCBIT2T-CHM13v2.0
Ywhah
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39533,176,160 - 33,185,310 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl533,176,160 - 33,185,310 (+)EnsemblGRCm39 Ensembl
GRCm38533,018,816 - 33,027,966 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl533,018,816 - 33,027,966 (+)EnsemblGRCm38mm10GRCm38
MGSCv37533,361,465 - 33,370,615 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36533,329,757 - 33,344,823 (+)NCBIMGSCv36mm8
Celera530,495,248 - 30,504,397 (+)NCBICelera
Cytogenetic Map5B1NCBI
cM Map517.42NCBI
Ywhah
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81481,920,819 - 81,930,202 (-)NCBIGRCr8
mRatBN7.21477,696,332 - 77,705,715 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1477,696,333 - 77,705,741 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1482,138,138 - 82,147,522 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01483,378,671 - 83,388,056 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01479,823,989 - 79,833,373 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01483,053,041 - 83,062,424 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1483,053,041 - 83,062,424 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01483,739,009 - 83,748,391 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41483,448,395 - 83,457,778 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11483,454,749 - 83,464,132 (-)NCBI
Celera1476,611,913 - 76,621,296 (-)NCBICelera
Cytogenetic Map14q21NCBI
Ywhah
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554556,045,919 - 6,057,729 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554556,045,919 - 6,057,729 (+)NCBIChiLan1.0ChiLan1.0
YWHAH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12624,785,374 - 24,796,603 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2624,785,368 - 24,795,778 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2624,653,699 - 24,664,927 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02625,171,660 - 25,183,107 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2625,170,742 - 25,183,121 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12624,870,912 - 24,882,134 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02625,132,984 - 25,144,210 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02625,195,163 - 25,206,388 (+)NCBIUU_Cfam_GSD_1.0
Ywhah
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118118,339,882 - 118,351,331 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367551,597,445 - 1,609,003 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367551,597,487 - 1,608,915 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
YWHAH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1448,544,173 - 48,556,490 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11448,544,031 - 48,556,496 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21451,861,302 - 51,873,780 (+)NCBISscrofa10.2Sscrofa10.2susScr3
YWHAH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11914,825,963 - 14,839,668 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1914,826,135 - 14,840,325 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045111,267,273 - 111,281,244 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ywhah
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247478,350,474 - 8,363,576 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247478,350,552 - 8,362,610 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034948734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000047342   ⟹   ENSPPAP00000024517
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2230,819,821 - 30,831,804 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000047345   ⟹   ENSPPAP00000024520
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2230,819,821 - 30,831,167 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000047347   ⟹   ENSPPAP00000024522
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2230,826,424 - 30,831,804 (+)Ensembl
RefSeq Acc Id: XM_034948734   ⟹   XP_034804625
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22341,896,667 - 41,909,802 (+)NCBI
NHGRI_mPanPan12244,597,258 - 44,610,288 (+)NCBI
Mhudiblu_PPA_v02212,966,653 - 12,979,695 (+)NCBI
Protein Sequences
Protein RefSeqs XP_034804625 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000024517.1
  ENSPPAP00000024520.1
  ENSPPAP00000024522.1
RefSeq Acc Id: XP_034804625   ⟸   XM_034948734
- UniProtKB: A0A2R9B4K5 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000024517   ⟸   ENSPPAT00000047342
Ensembl Acc Id: ENSPPAP00000024522   ⟸   ENSPPAT00000047347
Ensembl Acc Id: ENSPPAP00000024520   ⟸   ENSPPAT00000047345
Protein Domains
14-3-3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035396 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000047342.1 UniProtKB/TrEMBL
  ENSPPAT00000047345.1 UniProtKB/TrEMBL
  ENSPPAT00000047347.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.190.20 UniProtKB/TrEMBL
InterPro 14-3-3 UniProtKB/TrEMBL
  14-3-3_CS UniProtKB/TrEMBL
  14-3-3_dom_sf UniProtKB/TrEMBL
  14-3-3_domain UniProtKB/TrEMBL
NCBI Gene YWHAH ENTREZGENE
PANTHER 14-3-3 PROTEIN ETA UniProtKB/TrEMBL
  PTHR18860 UniProtKB/TrEMBL
Pfam 14-3-3 UniProtKB/TrEMBL
PIRSF 14-3-3 UniProtKB/TrEMBL
PRINTS 1433ZETA UniProtKB/TrEMBL
PROSITE 1433_1 UniProtKB/TrEMBL
  1433_2 UniProtKB/TrEMBL
SMART 14_3_3 UniProtKB/TrEMBL
Superfamily-SCOP SSF48445 UniProtKB/TrEMBL
UniProt A0A2R9B4K5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9B4L0_PANPA UniProtKB/TrEMBL
  A0A2R9B8D9_PANPA UniProtKB/TrEMBL