HBA1 (hemoglobin subunit alpha 1) - Rat Genome Database

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Gene: HBA1 (hemoglobin subunit alpha 1) Pan paniscus
Analyze
Symbol: HBA1 (Ensembl: HBA2)
Name: hemoglobin subunit alpha 1 (Ensembl:hemoglobin subunit alpha 2)
RGD ID: 12025398
Description: ENCODES a protein that exhibits G protein-coupled receptor binding (ortholog); haptoglobin binding (ortholog); peroxidase activity (ortholog); INVOLVED IN erythrocyte development (ortholog); in utero embryonic development (ortholog); response to bacterium (ortholog); ASSOCIATED WITH alpha thalassemia (ortholog); Alpha-Thalassemia 2 (ortholog); Alpha-Thalassemia-2, Nondeletional (ortholog); FOUND IN blood microparticle (inferred); extracellular space (inferred); haptoglobin-hemoglobin complex (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Alpha-globin; HBA2; hemoglobin alpha 2; Hemoglobin alpha chain; hemoglobin subunit alpha
RGD Orthologs
Human
Mouse
Rat
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218387,821 - 388,716 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,180,776 - 4,181,647 (+)NCBINHGRI_mPanPan1
PanPan1.116164,614 - 165,476 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16164,618 - 165,476 (+)Ensemblpanpan1.1panPan2


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:6406908   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
HBA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218387,821 - 388,716 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,180,776 - 4,181,647 (+)NCBINHGRI_mPanPan1
PanPan1.116164,614 - 165,476 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16164,618 - 165,476 (+)Ensemblpanpan1.1panPan2
HBA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816176,680 - 177,522 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16176,680 - 177,522 (+)EnsemblGRCh38hg38GRCh38
GRCh3716226,679 - 227,521 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616166,679 - 167,520 (+)NCBINCBI36Build 36hg18NCBI36
Build 3416166,678 - 167,520NCBI
Celera16426,194 - 427,035 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef16144,721 - 145,562 (+)NCBIHuRef
CHM1_116226,686 - 227,527 (+)NCBICHM1_1
T2T-CHM13v2.016170,722 - 171,564 (+)NCBIT2T-CHM13v2.0
Hba-a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,233,672 - 32,234,486 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,233,511 - 32,234,465 (+)EnsemblGRCm39 Ensembl
GRCm381132,283,672 - 32,284,486 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,283,511 - 32,284,465 (+)EnsemblGRCm38mm10GRCm38
MGSCv371132,183,672 - 32,184,486 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,261,880 - 32,262,699 (+)NCBIMGSCv36mm8
MGSCv361132,183,674 - 32,184,493 (+)NCBIMGSCv36mm8
Celera1134,700,973 - 34,701,816 (+)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1118.86NCBI
Hba-a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,828,291 - 15,829,138 (-)NCBIGRCr8
mRatBN7.21015,323,830 - 15,324,677 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1015,307,815 - 15,338,392 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1020,070,156 - 20,071,003 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,559,041 - 19,559,888 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01015,051,812 - 15,052,659 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,589,364 - 15,590,207 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,589,364 - 15,590,220 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,484,459 - 15,485,302 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,570,930 - 15,571,773 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11015,571,977 - 15,572,821 (-)NCBI
Celera1014,991,420 - 14,992,263 (-)NCBICelera
Cytogenetic Map10q12NCBI
LOC100855540
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1640,324,378 - 40,325,427 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,588,015 - 41,589,066 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0640,667,527 - 40,668,582 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1640,355,646 - 40,356,696 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0640,316,610 - 40,317,658 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,795,235 - 40,796,286 (-)NCBIUU_Cfam_GSD_1.0
LOC110259958
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1341,482,353 - 41,483,564 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003809390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000030893   ⟹   ENSPPAP00000008258
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl16164,618 - 165,476 (+)Ensembl
RefSeq Acc Id: XM_003809390   ⟹   XP_003809438
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v218387,821 - 388,716 (+)NCBI
NHGRI_mPanPan1164,180,776 - 4,181,647 (+)NCBI
PanPan1.116164,614 - 165,476 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003809438 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000008258
  ENSPPAP00000008258.1
  ENSPPAP00000024616.1
GenBank Protein P69906 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_003809438   ⟸   XM_003809390
- UniProtKB: P69906 (UniProtKB/Swiss-Prot),   A0A2R9B6C3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000008258   ⟸   ENSPPAT00000030893
Protein Domains
GLOBIN


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000027365 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSPPAG00000035441 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000030893.1 UniProtKB/Swiss-Prot
  ENSPPAT00000047441.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.490.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Globin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Globin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Globin/Proto UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Haemoglobin_a-typ UniProtKB/Swiss-Prot
  Haemoglobin_pi UniProtKB/Swiss-Prot
  Hemoglobin_a-typ UniProtKB/TrEMBL
  Hemoglobin_oxygen_transport UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report pps:100983142 UniProtKB/Swiss-Prot
NCBI Gene HBA2 ENTREZGENE
PANTHER HEMOGLOBIN FAMILY MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEMOGLOBIN SUBUNIT ALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Globin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS ALPHAHAEM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PIHAEM UniProtKB/Swiss-Prot
PROSITE GLOBIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Globin-like UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A0A2R9B6C3 ENTREZGENE, UniProtKB/TrEMBL
  HBA_PANPA UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P01922 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-03-13 HBA1  hemoglobin subunit alpha 1  HBA2  hemoglobin alpha 2  Symbol and/or name change 5135510 APPROVED