CIITA (class II major histocompatibility complex transactivator) - Rat Genome Database

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Gene: CIITA (class II major histocompatibility complex transactivator) Pan paniscus
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Symbol: CIITA
Name: class II major histocompatibility complex transactivator
RGD ID: 11983652
Description: ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); protein C-terminus binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN aging (ortholog); cellular response to electrical stimulus (ortholog); cellular response to exogenous dsRNA (ortholog); ASSOCIATED WITH acute kidney tubular necrosis (ortholog); Addison's disease (ortholog); Albuminuria (ortholog); FOUND IN cell surface (ortholog); cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: MHC class II transactivator
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11611,041,434 - 11,090,485 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1611,041,434 - 11,090,485 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0169,819,440 - 9,885,379 (+)NCBIMhudiblu_PPA_v0panPan3
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Genomics

Comparative Map Data
CIITA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11611,041,434 - 11,090,485 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1611,041,434 - 11,090,485 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0169,819,440 - 9,885,379 (+)NCBIMhudiblu_PPA_v0panPan3
CIITA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1610,866,222 - 10,943,021 (+)EnsemblGRCh38hg38GRCh38
GRCh381610,866,208 - 10,941,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371610,971,055 - 11,030,251 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361610,878,556 - 10,926,341 (+)NCBINCBI36hg18NCBI36
Build 341610,878,539 - 10,933,676NCBI
Celera1611,140,481 - 11,188,432 (+)NCBI
Cytogenetic Map16p13.13NCBI
HuRef1610,888,898 - 10,936,424 (+)NCBIHuRef
CHM1_11610,970,985 - 11,018,760 (+)NCBICHM1_1
Ciita
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391610,297,877 - 10,348,928 (+)NCBIGRCm39mm39
GRCm39 Ensembl1610,297,923 - 10,346,282 (+)Ensembl
GRCm381610,480,014 - 10,531,064 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1610,480,059 - 10,528,418 (+)EnsemblGRCm38mm10GRCm38
MGSCv371610,488,372 - 10,527,657 (+)NCBIGRCm37mm9NCBIm37
MGSCv361610,401,857 - 10,441,142 (+)NCBImm8
Celera1611,120,578 - 11,160,248 (+)NCBICelera
Cytogenetic Map16A1NCBI
Ciita
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2105,139,947 - 5,187,493 (-)NCBI
Rnor_6.0 Ensembl105,213,350 - 5,260,608 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0105,212,621 - 5,260,641 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0104,036,437 - 4,083,966 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4105,087,174 - 5,133,418 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1105,087,173 - 5,133,418 (-)NCBI
Celera104,158,435 - 4,205,434 (-)NCBICelera
Cytogenetic Map10q11NCBI
Ciita
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554427,603,893 - 7,647,624 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554427,600,903 - 7,647,619 (-)NCBIChiLan1.0ChiLan1.0
CIITA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1631,774,486 - 31,837,025 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl631,774,609 - 31,836,820 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha633,156,962 - 33,219,510 (-)NCBI
ROS_Cfam_1.0631,956,967 - 32,019,399 (-)NCBI
UMICH_Zoey_3.1631,770,183 - 31,832,926 (-)NCBI
UNSW_CanFamBas_1.0631,644,456 - 31,706,901 (-)NCBI
UU_Cfam_GSD_1.0632,068,973 - 32,131,721 (-)NCBI
Ciita
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344111,196,647 - 111,229,034 (+)NCBI
SpeTri2.0NW_0049365309,033,510 - 9,073,341 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CIITA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl332,172,214 - 32,230,780 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1332,171,706 - 32,230,775 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2333,109,119 - 33,117,697 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CIITA
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1510,341,690 - 10,401,988 (+)NCBI
ChlSab1.1 Ensembl510,372,344 - 10,400,451 (+)Ensembl
Vero_WHO_p1.0NW_02366606819,764,657 - 19,814,384 (-)NCBI
Ciita
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248248,099,877 - 8,156,661 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSPPAT00000048530   ⟹   ENSPPAP00000025700
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1611,041,434 - 11,090,485 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000048537   ⟹   ENSPPAP00000025707
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1611,041,567 - 11,088,806 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000048538   ⟹   ENSPPAP00000025708
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1611,041,567 - 11,075,608 (+)Ensembl
RefSeq Acc Id: ENSPPAT00000048539   ⟹   ENSPPAP00000025709
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1611,060,499 - 11,088,806 (+)Ensembl
RefSeq Acc Id: XM_003808285   ⟹   XP_003808333
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11611,041,434 - 11,090,366 (+)NCBI
Mhudiblu_PPA_v0169,819,484 - 9,868,223 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008960373   ⟹   XP_008958621
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11611,041,434 - 11,090,485 (+)NCBI
Mhudiblu_PPA_v0169,819,440 - 9,868,223 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008960374   ⟹   XP_008958622
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.11611,043,203 - 11,089,844 (+)NCBI
Mhudiblu_PPA_v0169,820,961 - 9,867,712 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034939778   ⟹   XP_034795669
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0169,820,960 - 9,879,684 (+)NCBI
RefSeq Acc Id: XM_034939779   ⟹   XP_034795670
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0169,820,960 - 9,885,379 (+)NCBI
RefSeq Acc Id: XM_034939780   ⟹   XP_034795671
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0169,820,960 - 9,878,488 (+)NCBI
RefSeq Acc Id: XM_034939781   ⟹   XP_034795672
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0169,820,961 - 9,867,712 (+)NCBI
RefSeq Acc Id: XM_034939782   ⟹   XP_034795673
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0169,819,488 - 9,879,684 (+)NCBI
RefSeq Acc Id: XM_034939783   ⟹   XP_034795674
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0169,819,488 - 9,879,684 (+)NCBI
RefSeq Acc Id: XM_034939784   ⟹   XP_034795675
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0169,820,959 - 9,867,712 (+)NCBI
RefSeq Acc Id: XM_034939785   ⟹   XP_034795676
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0169,820,957 - 9,867,712 (+)NCBI
RefSeq Acc Id: XM_034939786   ⟹   XP_034795677
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0169,820,961 - 9,867,712 (+)NCBI
RefSeq Acc Id: XM_034939787   ⟹   XP_034795678
RefSeq Status:
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
Mhudiblu_PPA_v0169,820,951 - 9,852,451 (+)NCBI
Reference Sequences
RefSeq Acc Id: XP_008958621   ⟸   XM_008960373
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_003808333   ⟸   XM_003808285
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008958622   ⟸   XM_008960374
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_034795673   ⟸   XM_034939782
- Peptide Label: isoform X3
RefSeq Acc Id: XP_034795674   ⟸   XM_034939783
- Peptide Label: isoform X4
RefSeq Acc Id: XP_034795678   ⟸   XM_034939787
- Peptide Label: isoform X8
RefSeq Acc Id: XP_034795676   ⟸   XM_034939785
- Peptide Label: isoform X6
RefSeq Acc Id: XP_034795675   ⟸   XM_034939784
- Peptide Label: isoform X5
RefSeq Acc Id: XP_034795670   ⟸   XM_034939779
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034795669   ⟸   XM_034939778
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034795671   ⟸   XM_034939780
- Peptide Label: isoform X1
RefSeq Acc Id: XP_034795672   ⟸   XM_034939781
- Peptide Label: isoform X2
RefSeq Acc Id: XP_034795677   ⟸   XM_034939786
- Peptide Label: isoform X7
RefSeq Acc Id: ENSPPAP00000025707   ⟸   ENSPPAT00000048537
RefSeq Acc Id: ENSPPAP00000025708   ⟸   ENSPPAT00000048538
RefSeq Acc Id: ENSPPAP00000025709   ⟸   ENSPPAT00000048539
RefSeq Acc Id: ENSPPAP00000025700   ⟸   ENSPPAT00000048530
Protein Domains
NACHT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000035964 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSPPAP00000025700 UniProtKB/TrEMBL
  ENSPPAP00000025707 UniProtKB/TrEMBL
  ENSPPAP00000025708 UniProtKB/TrEMBL
  ENSPPAP00000025709 UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000048530 UniProtKB/TrEMBL
  ENSPPAT00000048537 UniProtKB/TrEMBL
  ENSPPAT00000048538 UniProtKB/TrEMBL
  ENSPPAT00000048539 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro Leu-rich_rpt UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/TrEMBL
  MHC_II_transact UniProtKB/TrEMBL
  NACHT_NTPase UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene CIITA ENTREZGENE
Pfam LRR_6 UniProtKB/TrEMBL
  NACHT UniProtKB/TrEMBL
PRINTS MHCIIACTVATR UniProtKB/TrEMBL
PROSITE LRR UniProtKB/TrEMBL
  NACHT UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt A0A2R9B7Y5_PANPA UniProtKB/TrEMBL
  A0A2R9B7Z1_PANPA UniProtKB/TrEMBL
  A0A2R9B9E3_PANPA UniProtKB/TrEMBL
  A0A2R9BFB3_PANPA UniProtKB/TrEMBL