PPT1 (palmitoyl-protein thioesterase 1) - Rat Genome Database

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Gene: PPT1 (palmitoyl-protein thioesterase 1) Pan paniscus
Analyze
Symbol: PPT1
Name: palmitoyl-protein thioesterase 1
RGD ID: 11983627
Description: ENCODES a protein that exhibits hydrolase activity (inferred); long-chain fatty acyl-CoA hydrolase activity (inferred); lysophosphatidic acid binding (inferred); INVOLVED IN adult locomotory behavior (ortholog); associative learning (ortholog); grooming behavior (ortholog); PARTICIPATES IN fatty acid elongation pathway; ASSOCIATED WITH Charcot-Marie-Tooth disease dominant intermediate C (ortholog); congenital myopathy 1A (ortholog); COVID-19 (ortholog); FOUND IN lysosomal membrane (ortholog); neuronal cell body (ortholog); presynaptic cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21186,729,114 - 186,753,833 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11185,866,794 - 185,891,455 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0139,358,424 - 39,383,087 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1140,683,841 - 40,708,609 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl140,683,841 - 40,708,609 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PPT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21186,729,114 - 186,753,833 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11185,866,794 - 185,891,455 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0139,358,424 - 39,383,087 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1140,683,841 - 40,708,609 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl140,683,841 - 40,708,609 (-)Ensemblpanpan1.1panPan2
PPT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38140,071,461 - 40,097,252 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl140,072,710 - 40,097,260 (-)EnsemblGRCh38hg38GRCh38
GRCh37140,537,133 - 40,562,924 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36140,310,969 - 40,335,555 (-)NCBINCBI36Build 36hg18NCBI36
Build 34140,207,476 - 40,232,061NCBI
Celera138,820,669 - 38,845,442 (-)NCBICelera
Cytogenetic Map1p34.2NCBI
HuRef138,656,433 - 38,681,192 (-)NCBIHuRef
CHM1_1140,653,983 - 40,678,773 (-)NCBICHM1_1
T2T-CHM13v2.0139,940,889 - 39,966,711 (-)NCBIT2T-CHM13v2.0
Ppt1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394122,729,879 - 122,752,968 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4122,730,035 - 122,752,968 (+)EnsemblGRCm39 Ensembl
GRCm384122,836,077 - 122,859,175 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4122,836,242 - 122,859,175 (+)EnsemblGRCm38mm10GRCm38
MGSCv374122,513,485 - 122,536,418 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364122,338,558 - 122,360,685 (+)NCBIMGSCv36mm8
Celera4121,166,717 - 121,189,624 (+)NCBICelera
Cytogenetic Map4D2.2NCBI
cM Map457.27NCBI
Ppt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85140,406,318 - 140,427,201 (+)NCBIGRCr8
mRatBN7.25135,121,164 - 135,142,048 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5135,121,163 - 135,142,048 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5137,827,992 - 137,847,852 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05139,598,471 - 139,618,368 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05139,605,087 - 139,624,952 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05140,538,260 - 140,558,163 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5140,538,260 - 140,558,162 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05144,329,263 - 144,349,162 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45142,153,498 - 142,173,401 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15142,158,725 - 142,179,598 (+)NCBI
Celera5133,659,813 - 133,679,711 (+)NCBICelera
RH 3.4 Map5890.0RGD
Cytogenetic Map5q36NCBI
Ppt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545217,529,115 - 17,549,664 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545217,518,345 - 17,549,112 (-)NCBIChiLan1.0ChiLan1.0
PPT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1152,815,428 - 2,886,474 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl152,859,979 - 2,894,425 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha153,117,325 - 3,143,210 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0152,902,313 - 2,973,313 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl152,946,653 - 2,981,365 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1152,854,181 - 2,880,060 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0152,914,086 - 2,939,964 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0152,930,482 - 2,956,365 (+)NCBIUU_Cfam_GSD_1.0
Ppt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505856,056,908 - 56,081,782 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647421,881,712 - 21,906,569 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647421,881,692 - 21,906,564 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PPT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl695,840,908 - 95,860,858 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1695,840,906 - 95,860,858 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2689,280,518 - 89,300,475 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PPT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12092,809,373 - 92,833,048 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2092,809,552 - 92,833,244 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603324,006,277 - 24,030,955 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ppt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476422,543,857 - 22,577,121 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476422,542,892 - 22,577,077 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003815421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000058445   ⟹   ENSPPAP00000035556
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl140,683,841 - 40,708,609 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000058456   ⟹   ENSPPAP00000035567
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl140,685,191 - 40,708,382 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000058460   ⟹   ENSPPAP00000035571
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl140,685,191 - 40,708,382 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000058463   ⟹   ENSPPAP00000035574
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl140,685,191 - 40,708,382 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000058466   ⟹   ENSPPAP00000035577
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl140,686,263 - 40,708,382 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000058467   ⟹   ENSPPAP00000035578
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl140,700,665 - 40,708,382 (-)Ensembl
RefSeq Acc Id: XM_003815421   ⟹   XP_003815469
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21186,729,114 - 186,753,833 (+)NCBI
NHGRI_mPanPan11185,866,794 - 185,891,455 (+)NCBI
Mhudiblu_PPA_v0139,358,424 - 39,383,087 (-)NCBI
PanPan1.1140,683,841 - 40,708,609 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003815469 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000035556
  ENSPPAP00000035556.1
  ENSPPAP00000035567.1
  ENSPPAP00000035571.1
  ENSPPAP00000035574.1
  ENSPPAP00000035577.1
  ENSPPAP00000035578.1
RefSeq Acc Id: XP_003815469   ⟸   XM_003815421
- UniProtKB: A0A2R9C1E5 (UniProtKB/TrEMBL),   A0A2R9C1G0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000035556   ⟸   ENSPPAT00000058445
Ensembl Acc Id: ENSPPAP00000035567   ⟸   ENSPPAT00000058456
Ensembl Acc Id: ENSPPAP00000035574   ⟸   ENSPPAT00000058463
Ensembl Acc Id: ENSPPAP00000035577   ⟸   ENSPPAT00000058466
Ensembl Acc Id: ENSPPAP00000035578   ⟸   ENSPPAT00000058467
Ensembl Acc Id: ENSPPAP00000035571   ⟸   ENSPPAT00000058460


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040559 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000058445.1 UniProtKB/TrEMBL
  ENSPPAT00000058456.1 UniProtKB/TrEMBL
  ENSPPAT00000058460.1 UniProtKB/TrEMBL
  ENSPPAT00000058463.1 UniProtKB/TrEMBL
  ENSPPAT00000058466.1 UniProtKB/TrEMBL
  ENSPPAT00000058467.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/TrEMBL
  Palm_thioest UniProtKB/TrEMBL
KEGG Report pps:100969155 UniProtKB/TrEMBL
NCBI Gene PPT1 ENTREZGENE
PANTHER PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1 UniProtKB/TrEMBL
  PTHR11247:SF8 UniProtKB/TrEMBL
Pfam Palm_thioest UniProtKB/TrEMBL
PRINTS F138DOMAIN UniProtKB/TrEMBL
  PPTHIESTRASE UniProtKB/TrEMBL
Superfamily-SCOP SSF53474 UniProtKB/TrEMBL
UniProt A0A2R9C0Y5_PANPA UniProtKB/TrEMBL
  A0A2R9C0Y7_PANPA UniProtKB/TrEMBL
  A0A2R9C0Z8_PANPA UniProtKB/TrEMBL
  A0A2R9C1E5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C1G0 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9CB37_PANPA UniProtKB/TrEMBL