PSMB5 (proteasome 20S subunit beta 5) - Rat Genome Database

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Gene: PSMB5 (proteasome 20S subunit beta 5) Pan paniscus
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Symbol: PSMB5
Name: proteasome 20S subunit beta 5
RGD ID: 11954538
Description: ENCODES a protein that exhibits peptidase activity (inferred); threonine-type endopeptidase activity (inferred); INVOLVED IN proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog); proteolysis (ortholog); response to oxidative stress (ortholog); ASSOCIATED WITH Brain-Lung-Thyroid Syndrome (ortholog); lysinuric protein intolerance (ortholog); Myocardial Ischemia (ortholog); FOUND IN cytoplasm (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: proteasome (prosome, macropain) subunit, beta type, 5; proteasome subunit beta 5; proteasome subunit beta type-5
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,458,581 - 24,467,983 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,675,069 - 23,684,471 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,845,951 - 3,855,335 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11421,943,432 - 21,952,169 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1421,943,432 - 21,952,169 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
PSMB5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,458,581 - 24,467,983 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,675,069 - 23,684,471 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,845,951 - 3,855,335 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11421,943,432 - 21,952,169 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1421,943,432 - 21,952,169 (-)Ensemblpanpan1.1panPan2
PSMB5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381423,025,851 - 23,035,220 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1423,016,543 - 23,035,230 (-)EnsemblGRCh38hg38GRCh38
GRCh371423,495,060 - 23,504,429 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,564,900 - 22,573,949 (-)NCBINCBI36Build 36hg18NCBI36
Build 341422,564,899 - 22,573,949NCBI
Celera143,357,950 - 3,367,323 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,612,363 - 3,621,723 (-)NCBIHuRef
CHM1_11423,493,694 - 23,503,063 (-)NCBICHM1_1
T2T-CHM13v2.01417,226,471 - 17,235,840 (-)NCBIT2T-CHM13v2.0
Psmb5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,851,577 - 54,855,452 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,851,576 - 54,855,479 (-)EnsemblGRCm39 Ensembl
GRCm381454,614,120 - 54,617,995 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,614,119 - 54,618,022 (-)EnsemblGRCm38mm10GRCm38
MGSCv371455,232,957 - 55,236,832 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361453,568,325 - 53,572,200 (-)NCBIMGSCv36mm8
Celera1452,402,497 - 52,406,386 (-)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.86NCBI
Psmb5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81532,042,784 - 32,047,379 (-)NCBIGRCr8
mRatBN7.21528,072,772 - 28,077,367 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1528,072,781 - 28,077,440 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1529,911,955 - 29,916,437 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01531,059,168 - 31,063,650 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01529,308,790 - 29,313,379 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01533,259,039 - 33,263,634 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,259,043 - 33,263,659 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01537,143,058 - 37,147,105 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,689,859 - 32,694,364 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11532,705,562 - 32,710,051 (-)NCBI
Celera1527,651,286 - 27,655,779 (-)NCBICelera
Cytogenetic Map15p13NCBI
Psmb5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540937,268,980 - 37,279,937 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540937,269,319 - 37,278,957 (+)NCBIChiLan1.0ChiLan1.0
PSMB5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.183,344,157 - 3,349,921 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl83,344,233 - 3,349,926 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha83,292,754 - 3,298,523 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.083,452,136 - 3,457,902 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,452,139 - 3,457,839 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,143,540 - 3,149,316 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,204,769 - 3,210,546 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,466,833 - 3,472,610 (-)NCBIUU_Cfam_GSD_1.0
Psmb5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,095,360 - 35,103,510 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367221,285,482 - 1,295,106 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367221,285,488 - 1,293,637 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSMB5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1776,014,576 - 76,021,922 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,329,736 - 81,337,082 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PSMB5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12923,394,820 - 23,403,953 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2923,390,401 - 23,403,658 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605923,013,024 - 23,022,186 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psmb5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248209,505,725 - 9,513,034 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248209,506,119 - 9,513,034 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000063664   ⟹   ENSPPAP00000040745
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1421,943,432 - 21,952,169 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000063665   ⟹   ENSPPAP00000040746
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1421,943,900 - 21,951,816 (-)Ensembl
RefSeq Acc Id: XM_003808118   ⟹   XP_003808166
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21524,458,581 - 24,467,983 (-)NCBI
NHGRI_mPanPan11423,675,069 - 23,684,465 (-)NCBI
Mhudiblu_PPA_v0143,845,951 - 3,855,260 (-)NCBI
PanPan1.11421,943,432 - 21,952,169 (-)NCBI
Sequence:
RefSeq Acc Id: XM_034937288   ⟹   XP_034793179
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21524,458,581 - 24,467,979 (-)NCBI
NHGRI_mPanPan11423,675,069 - 23,684,471 (-)NCBI
Mhudiblu_PPA_v0143,845,951 - 3,855,335 (-)NCBI
Protein Sequences
Protein RefSeqs XP_003808166 (Get FASTA)   NCBI Sequence Viewer  
  XP_034793179 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000040745
  ENSPPAP00000040745.1
  ENSPPAP00000040746.1
RefSeq Acc Id: XP_003808166   ⟸   XM_003808118
- Peptide Label: isoform X1
- UniProtKB: A0A2R9CFM6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034793179   ⟸   XM_034937288
- Peptide Label: isoform X2
Ensembl Acc Id: ENSPPAP00000040745   ⟸   ENSPPAT00000063664
Ensembl Acc Id: ENSPPAP00000040746   ⟸   ENSPPAT00000063665


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000043004 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000063664.1 UniProtKB/TrEMBL
  ENSPPAT00000063665.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.20.10 UniProtKB/TrEMBL
InterPro Ntn_hydrolases_N UniProtKB/TrEMBL
  Pept_T1A_subB UniProtKB/TrEMBL
  Proteasome_bsu_CS UniProtKB/TrEMBL
  Proteasome_sua/b UniProtKB/TrEMBL
  Proteasome_suB-type UniProtKB/TrEMBL
KEGG Report pps:100988289 UniProtKB/TrEMBL
NCBI Gene PSMB5 ENTREZGENE
PANTHER METALLOPROTEASE TLDD UniProtKB/TrEMBL
  PROTEASOME SUBUNIT BETA UniProtKB/TrEMBL
Pfam Proteasome UniProtKB/TrEMBL
PRINTS PROTEASOME UniProtKB/TrEMBL
PROSITE PROTEASOME_BETA_1 UniProtKB/TrEMBL
  PROTEASOME_BETA_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF56235 UniProtKB/TrEMBL
UniProt A0A2R9CFK4_PANPA UniProtKB/TrEMBL
  A0A2R9CFM6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-09-03 PSMB5  proteasome 20S subunit beta 5  PSMB5  proteasome subunit beta 5  Symbol and/or name change 5135510 APPROVED