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Gene: TTC38 (tetratricopeptide repeat domain 38) Pan paniscus

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Symbol:

TTC38

Name:

tetratricopeptide repeat domain 38

RGD ID:

11937352

Description:

ASSOCIATED WITH intellectual disability (ortholog); Phelan-McDermid syndrome (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

tetratricopeptide repeat protein 38

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	56,094,810 - 56,123,432 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	58,794,326 - 58,821,455 (+)	NCBI		NHGRI_mPanPan1
PanPan1.1	22	45,333,321 - 45,360,053 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	45,333,321 - 45,360,053 (+)	Ensembl	panpan1.1		panPan2

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TTC38	Bonobo	intellectual disability		ISO	TTC38 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Intellectual disability	ClinVar
TTC38	Bonobo	Phelan-McDermid syndrome		ISO	TTC38 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Phelan-McDermid syndrome	ClinVar

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
TTC38	Bonobo	protein binding	enables	ISO	UniProtKB:Q99985	9068941	PMID:33961781	IntAct	PMID:33961781

PMID:22301074

TTC38
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	56,094,810 - 56,123,432 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	58,794,326 - 58,821,455 (+)	NCBI		NHGRI_mPanPan1
PanPan1.1	22	45,333,321 - 45,360,053 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	45,333,321 - 45,360,053 (+)	Ensembl	panpan1.1		panPan2

TTC38
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	46,268,008 - 46,294,008 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	46,267,961 - 46,294,008 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	22	46,663,905 - 46,689,905 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	45,042,525 - 45,068,569 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	22	30,571,246 - 30,597,288 (+)	NCBI		Celera
Cytogenetic Map	22	q13.31	NCBI
HuRef	22	29,607,837 - 29,633,914 (+)	NCBI		HuRef
CHM1_1	22	46,622,594 - 46,648,635 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	22	46,752,708 - 46,778,705 (+)	NCBI		T2T-CHM13v2.0

Ttc38
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	85,716,545 - 85,743,023 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	85,716,507 - 85,743,023 (+)	Ensembl		GRCm39 Ensembl
GRCm38	15	85,832,282 - 85,858,822 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	85,832,306 - 85,858,822 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	15	85,662,734 - 85,689,252 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	15	85,660,110 - 85,685,499 (+)	NCBI		MGSCv36	mm8
Celera	15	87,964,196 - 87,991,957 (+)	NCBI		Celera
Cytogenetic Map	15	E2	NCBI
cM Map	15	40.42	NCBI

Ttc38
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	118,805,115 - 118,828,449 (+)	NCBI		GRCr8
mRatBN7.2	7	116,925,273 - 116,948,616 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	116,925,257 - 116,948,611 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	118,676,127 - 118,697,459 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	120,901,755 - 120,923,085 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	120,871,316 - 120,892,648 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	126,711,674 - 126,735,013 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	126,711,467 - 126,735,007 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	126,422,437 - 126,446,125 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	123,837,048 - 123,858,284 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	123,870,917 - 123,892,294 (+)	NCBI
Celera	7	113,216,370 - 113,237,599 (+)	NCBI		Celera
Cytogenetic Map	7	q34	NCBI

Ttc38
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	30,390,722 - 30,413,955 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955413	30,391,385 - 30,411,210 (+)	NCBI	ChiLan1.0	ChiLan1.0

TTC38
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	19,887,285 - 19,910,347 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	19,773,373 - 19,910,683 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	19,809,856 - 19,832,910 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	20,620,897 - 20,644,214 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	20,620,908 - 20,644,218 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	20,341,478 - 20,364,501 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	20,654,310 - 20,677,329 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	20,836,049 - 20,859,104 (-)	NCBI		UU_Cfam_GSD_1.0

Ttc38
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	3,619,198 - 3,640,103 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936629	3,619,175 - 3,640,304 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936629	3,619,190 - 3,640,046 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

TTC38
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	3,248,346 - 3,270,778 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	5	3,248,342 - 3,270,815 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	520,842 - 543,411 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

TTC38
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	28,749,590 - 28,775,475 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	28,749,657 - 28,777,171 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	96,755,394 - 96,781,722 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ttc38
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624752	3,576,695 - 3,602,658 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624752	3,578,459 - 3,602,650 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_003812380	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000023	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000027675 ⟹ ENSPPAP00000006423

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	22	45,333,321 - 45,360,053 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000027678 ⟹ ENSPPAP00000006425

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	22	45,333,391 - 45,334,528 (+)	Ensembl

RefSeq Acc Id:

XM_003812380 ⟹ XP_003812428

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	23	56,094,810 - 56,123,432 (+)	NCBI
NHGRI_mPanPan1	22	58,794,326 - 58,821,455 (+)	NCBI
PanPan1.1	22	45,333,321 - 45,360,053 (+)	NCBI

Sequence:

show sequence

CGCCCGCCCCGCCCACTCCCCGGAAGGCCCGGGTGCCCAGAGCTCGCGGTGGACTCCGACCCGGCGCAACATGGCCGCACCCTCGCCTCTGCGCGACTGCCAGGCCTGGAAGGATGCGAGGCTCCCGC
TCTCCACCACAAGCAACGAAGCCTGCAAGCTGTTCGATGCCACGCTGACCCAGTATGTAAAATGGACCAATGACAAGAGTCTCGGTGGCATCGAGGGCTGCCTGTCAAAGCTGAAAGCAGCAGATCCA
ACCTTTGTGATGGGCCACGCCATCGCTACTGGCCTTGTGCTGATTGGCACTGGAAGCTCCGTGAAGCTGGACAAAGAGCTGGACCTGGCTGTGAAGACAATGGTGGAGATTTCAAGAACCCAGCCGCT
GACAAGGCGGGAGCAGCTGCACGTGTCTGCAGTAGAGACATTTGCCAATGGGAACTTTCCGAAAGCCTGCGAACTATGGGAACAGATTCTCCAGGACCACCCGACAGACATGTTGGCCCTGAAATTTT
CCCATGATGCTTATTTTTACCTGGGCTATCAGGAACAGATGAGAGATTCTGTTGCTCGAATTTACCCCTTCTGGACACCTGATATCCCCCTAAGCAGCTATGTGAAAGGCATCTACTCTTTTGGCTTG
ATGGAAACCAACTTCTACGACCGGGCAGAAAAACTCGCCAAAGAGGCTTTGTCTATTAACCCGACAGACGCATGGTCGGTGCACACCATCGCTCACATCCACGAGATGAAAGCAGAGATCAAGGATGG
GTTGGAATTCATGCAGCACTCAGAGACCCTCTGGAAGGACTCTGATATGTTGGCTTGTCATAACTATTGGCACTGGGCTTTATATCTGATTGAGAAGGGCGAATATGAGGCCGCGCTGACCATCTACG
ATACCCACATCCTTCCCAGCCTGCAGGCCAACGGTGCAATGCTGGACATGGTGGACAGCAGCTCCATGCTCTACCGCCTGCAGATGGAAGGAGTGTCTGTGGGCCAGCGGTGGCAGGATGTCTTGCCT
GTGGCCCGGAAGCACAGCCGAGACCACATCCTGCTGTTCAATGACGCACACTTCCTGATGGCATCCCTGGGTGCACACGACCCCCAGACCACACAGGAGCTGCTGACCACCCTGCGGGACGCCAGCGA
ATCCCCAGGGGAGAACTGCCAGCACCTCCTGGCCCGAGACGTGGGGCTGCCCCTGTGCCAGGCCCTGGTGGAGGCTGAGGACGGGAACCCTGACCGCGTCCTGGAGCTGCTCCTGCCCATCCGCTACC
GGATCGTCCAGCTCGGTGGGAGCAATGCCCAGAGAGACGTCTTCAACCAGCTGCTGATTCACACGGCCTTAAACTGCACCTCCAGCGTCCATAAGAACGTAGCCCGGAGCCTTCTGATGGAGCGTGAT
GCCTTGAAGCCCAACTCGCCCCTGACCGAGCGGCTCATCCGCAAGGCAGCTACCGTCCACCTCATGCAGTGAGCCAGCCTGGCCGCCTCCACCCTGTAGAACCTCAGTGGTGGCGTCACTGCGTCCAG
TCAGCTGCTCCACCGGGTTAGGGTCAGGAGACGGCCAGAGCCTGTTTGTTAGGGCTGTTAGAGGGTGATCTTCAGTTTTACAGGAAGTGGGTCACGGGTTAATTTTAAATGTGATTCCGAATCTCCTT
TCAGTCCTCGAGAAGGGCCAATGAGCATTTTTCAGCAGTCACAGCCAGTGTGAGTGCTGCTCTTTCCACCTGCCTTGCAAATTCTGTTTCCCAGGGGAATGTGTCTACTGCCTGGTGGTTCAAAGGTT
GGAAGGCAGGGCAGAGGTAGGGGCTGATTCTGCTGGGACAGGTCTTCCAGAGGCAGCCTCCCCCCACTGCCTGTCCCCGTCCCCACCAGGCTGCCCTTGGGATGGACCTTTTCATTCTTTTCTTTATA
TTCTAGACAGTCTCTGTTGTCTCATTGTGTTGCTGTCCCATTTTTCAGGTGAGGGTACCAGGGTAGGGGAGTGGCCTGCCCAGGGTCACACTATGAGAGGCCCCCACCTGCTGCCTTTGGACGCAGCC
CCCTGCTGCTGCATCCACCACCCTTCTTACAGATCAGCGTGCACATGGGGTCCTCCTGCTGTCTCTGGGGCGAGTCTTGGAGCCCCCTGGGGGGCTCTGTTGGTGCTGATTTGGACCCGTTTCTCTTT
TTAAACTGCACATCATAACAGGGCTTCATGTCGAGCATGATTTTAATCATAAATGCACTTCTGAGGTGCAAGGACTGAGCTCAGAGCTGCTCTGTTGTGGCAAAACCCAAAGTGCTGTGATGTGTGGC
TGTGACAAGCCTGGAGCGGGTCCTGTGAGCACCGCCTCTGTCTCCTGCTTCCCCACTGAACGCCTGCTGAATGTGCCGCTGACTCAGCTGTGCTGCTTTCAGCCCTCCTGTGAGGGGCGGTCCCAGTG
CACAGATGTTTTTCAAGTTCCTCAGTTTGTACTGAAATTAGGGATTCATCAGGGCAGGAAGCAGGCAGGCCTCTCAGAAGGGAGAGGAGGCCTCCAAATCTATTGAGTCCCCACAGTTTGCTCAAGCC
CAGGCAAATTTCTGTGATTAAAATGAATTCATCAGTTCCTCCAA

hide sequence


Protein RefSeqs	XP_003812428	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000006423.1
	ENSPPAP00000006425.1

RefSeq Acc Id:

XP_003812428 ⟸ XM_003812380

- UniProtKB:

A0A2R8ZN90 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAPSPLRDCQAWKDARLPLSTTSNEACKLFDATLTQYVKWTNDKSLGGIEGCLSKLKAADPTFVMGHAIATGLVLIGTGSSVKLDKELDLAVKTMVEISRTQPLTRREQLHVSAVETFANGNFPKAC
ELWEQILQDHPTDMLALKFSHDAYFYLGYQEQMRDSVARIYPFWTPDIPLSSYVKGIYSFGLMETNFYDRAEKLAKEALSINPTDAWSVHTIAHIHEMKAEIKDGLEFMQHSETLWKDSDMLACHNYW
HWALYLIEKGEYEAALTIYDTHILPSLQANGAMLDMVDSSSMLYRLQMEGVSVGQRWQDVLPVARKHSRDHILLFNDAHFLMASLGAHDPQTTQELLTTLRDASESPGENCQHLLARDVGLPLCQALV
EAEDGNPDRVLELLLPIRYRIVQLGGSNAQRDVFNQLLIHTALNCTSSVHKNVARSLLMERDALKPNSPLTERLIRKAATVHLMQ

hide sequence

Ensembl Acc Id:

ENSPPAP00000006425 ⟸ ENSPPAT00000027678

Ensembl Acc Id:

ENSPPAP00000006423 ⟸ ENSPPAT00000027675

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000025045	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000027675.1	UniProtKB/TrEMBL
	ENSPPAT00000027678.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.10	UniProtKB/TrEMBL
InterPro	TPR-like_helical_dom_sf	UniProtKB/TrEMBL
	TTC38	UniProtKB/TrEMBL
KEGG Report	pps:100974623	UniProtKB/TrEMBL
NCBI Gene	TTC38	ENTREZGENE
PANTHER	PTHR16263	UniProtKB/TrEMBL
	TETRATRICOPEPTIDE REPEAT PROTEIN 38	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48452	UniProtKB/TrEMBL
UniProt	A0A2R8ZN90	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R8ZPJ9_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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