ROBO4 (roundabout guidance receptor 4)

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Gene: ROBO4 (roundabout guidance receptor 4) Pan paniscus

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Symbol:

ROBO4

Name:

roundabout guidance receptor 4

RGD ID:

11922900

Description:

ENCODES a protein that exhibits signaling receptor activity (ortholog); INVOLVED IN blood vessel endothelial cell migration (ortholog); negative regulation of blood vessel endothelial cell migration (ortholog); ASSOCIATED WITH aortic aneurysm (ortholog); aortic valve disease 3 (ortholog); autistic disorder (ortholog); FOUND IN external side of plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

roundabout homolog 4; roundabout, axon guidance receptor, homolog 4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	125,579,458 - 125,593,121 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	126,684,362 - 126,697,997 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	119,711,023 - 119,724,701 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	123,626,063 - 123,639,793 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	123,626,063 - 123,639,837 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

aortic aneurysm (ISO)

aortic valve disease 3 (ISO)

autistic disorder (ISO)

bicuspid aortic valve disease (ISO)

chromosome 11 partial duplication syndrome (ISO)

congenital diaphragmatic hernia (ISO)

Dwarfism (ISO)

holoprosencephaly 11 (ISO)

Jacobsen Syndrome (ISO)

pre-eclampsia (ISO)

schizophrenia (ISO)

thoracic aortic aneurysm (ISO)

thyroid gland carcinoma (ISO)

transient cerebral ischemia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

angiogenesis (IEA)

axon guidance (IEA)

blood vessel endothelial cell migration (ISO)

dendrite self-avoidance (IEA)

establishment of endothelial barrier (IEA)

homophilic cell adhesion via plasma membrane adhesion molecules (IEA)

negative regulation of blood vessel endothelial cell migration (ISO)

Cellular Component

axon (IEA)

external side of plasma membrane (ISO)

plasma membrane (IEA)

Molecular Function

cell-cell adhesion mediator activity (IEA)

protein binding (ISO)

signaling receptor activity (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ROBO4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	125,579,458 - 125,593,121 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	126,684,362 - 126,697,997 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	119,711,023 - 119,724,701 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	123,626,063 - 123,639,793 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	123,626,063 - 123,639,837 (-)	Ensembl	panpan1.1		panPan2

ROBO4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	124,883,691 - 124,897,865 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	124,883,691 - 124,898,500 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	124,753,587 - 124,767,761 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	124,259,324 - 124,272,950 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	124,259,324 - 124,272,951	NCBI
Celera	11	121,914,289 - 121,928,006 (-)	NCBI		Celera
Cytogenetic Map	11	q24.2	NCBI
HuRef	11	120,696,466 - 120,710,183 (-)	NCBI		HuRef
CHM1_1	11	124,640,224 - 124,653,941 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	124,912,311 - 124,926,485 (-)	NCBI		T2T-CHM13v2.0

Robo4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	37,313,198 - 37,325,319 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	37,313,193 - 37,326,411 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	37,401,902 - 37,414,023 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	37,401,897 - 37,415,115 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	37,209,631 - 37,221,607 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	37,151,717 - 37,163,693 (+)	NCBI		MGSCv36	mm8
Celera	9	34,616,424 - 34,628,396 (+)	NCBI		Celera
Cytogenetic Map	9	A4	NCBI
cM Map	9	20.76	NCBI

Robo4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	45,308,739 - 45,322,522 (+)	NCBI		GRCr8
mRatBN7.2	8	37,119,953 - 37,133,887 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	37,119,988 - 37,132,519 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	8	39,878,900 - 39,891,485 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	39,878,955 - 39,890,942 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	39,879,806 - 39,892,371 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Cytogenetic Map	8	q22	NCBI

Robo4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	25,954,085 - 25,967,723 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	25,954,906 - 25,967,707 (-)	NCBI	ChiLan1.0	ChiLan1.0

ROBO4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	9,546,830 - 9,561,342 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	9,547,047 - 9,561,702 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	9,592,370 - 9,606,848 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	9,486,652 - 9,501,126 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	9,486,825 - 9,501,122 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	9,559,307 - 9,573,796 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	9,529,769 - 9,544,248 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	9,566,647 - 9,580,690 (+)	NCBI		UU_Cfam_GSD_1.0

Robo4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	107,074,254 - 107,089,138 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936743	1,318,718 - 1,336,689 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936743	1,321,816 - 1,336,682 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ROBO4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	52,083,760 - 52,097,736 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	52,083,757 - 52,097,784 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	57,599,263 - 57,613,277 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ROBO4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	116,027,516 - 116,041,771 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	116,026,834 - 116,041,422 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	10,076,903 - 10,090,940 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Robo4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624927	888,141 - 903,659 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624927	888,421 - 903,657 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003819930	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003819931	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034933960	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000009	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000019642 ⟹ ENSPPAP00000004232

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	11	123,626,063 - 123,639,837 (-)	Ensembl

RefSeq Acc Id:

XM_003819930 ⟹ XP_003819978

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	125,579,458 - 125,593,121 (-)	NCBI
NHGRI_mPanPan1	11	126,684,362 - 126,697,997 (-)	NCBI
Mhudiblu_PPA_v0	11	119,711,023 - 119,724,701 (-)	NCBI
PanPan1.1	11	123,626,063 - 123,639,787 (-)	NCBI

Sequence:

show sequence

GCTTCCCTCCTGGGGCAGAGTCTCGGTCACAAACAACCACCACCGGCCCACCCCGCCCCTCCTT
CCCTCTTCACTGTGAGCTCAGAGCAGCAGGACAAAGTGCTCGGGACAAGGACATAGGGCTGAGA
GTAGCCATGGGCTCTGGAGGAGAGAGCCTCCTGGGGGGCAGGGGTTCCCTGCCTCTGCTGCTCC
TGCTCATCATGGGAGGCATGGCTCAGGACTCCCCGCCCCAGATCCTAGTCCACCCCCAGGACCA
GCTGTTCCAGGGCCCTGGCCCTGCCAGGATGAGCTGCCGAGCCTCAGGCCAGCCACCTCCCACC
ATCCACTGGTTGCTGAATGGGCAGCCCCTGAGCATGGTGCCCCCAGACCCACACCACCTCCTGC
CTGATGGGACCCTTCTGCTGCTACAGCCCCCTGCCCGGGGACATGCCCACGATGGCCAGGCCCT
GTCCACAGACCTGGGTGTCTACACATGTGAGGCCAGCAACCGGCTTGGCACGGCAGTCAGCAGA
GGCGCTCGGCTGTCTGTGGCTGTCCTCCGGGAGGATTTCCAGATCCAGCCTCGGGACATGGTGG
CTGTGGTGGGTGAGCAGTTTACTCTGGAATGTGGGCCGCCCTGGGGCCACCCAGAGCCCACAGT
CTCATGGTGGAAAGATGGGAAACCCCTGGTCCTCCAGCCCGGAAGGCACACAGTGTCCGGGGGG
TCCCTGCTGATGGCAAGAGCAGAGAAGAGTGATGAAGGGACCTACATGTGTGTGGCCACCAACA
GCGCAGGACACAGGGAGAGCCGCGCAGCCCGGGTTTCCATCCAGGAGCCCCAGGACTACACGGA
GCCTGTGGAGCTTCTGGCTGTGCGAATTCAGCTGGAAAATGTGACACTGCTGAACCCGGATCCT
GCAAAGGGCCCCAAGCCTAGACCGGCGGTGTGGCTCAGCTGGAAGGTCAGTGGCCCTGCTGCGC
CTGCCCAATCTTACACGGCCTTGTTCAGGACCCAGACTGCCCCGGGAGGCCAGGGAGCTCCGTG
GGCAGAGGAGCTGCTGGCCGGCTGGCAGAGCGCAGAGCTTGGAGGCCTCCACTGGGGCCAAGAC
TACGAGTTCAAAGTGAGACCATCCTCTGGCCGGGCTCGAGGCCCTGACAGCAACGTGCTGCTCC
TGAGGCTGCCGGAAAAAGTGCCCAGTGCCCCACCTCAGGAGGTGACCCTAAAACCTGGCAATGG
CAGTGTCTTTGTGAGCTGGGTCCCACCACCTGCTGAAAACCACAATGGCATCATCCGTGGCTAC
CAGGTCTGGAGCCTGGGCAACACGTCACTGCCACCAGCCAACTGGACTGTAGTTGGTGAGCAGA
CCCAGCTGGAAATCGCCACCCATATGCCAGGCTCCTACTGCGTGCAAGTGGCTGCAGTCACTGG
TGCTGGAGCTGGGGAGCCCAGTAGACCTGTCTGCCTCCTTTTAGAGCAGGCCATGGAGCGAGCC
ACCCAAGAACCCAGTGAGCATGGTCCCTGGACCCTGGAGCAGCTGAGGGCTACCTTGAAGCGGC
CTGAGGTCATTGCCACCTGCGGTGTTGCACTCTGGCTGCTGCTTCTGGGCACCGCTGTGTGTAT
CCACCGCCGGCGCCGAGCTGGGGTGCACCTGGGCCCAGGTCTGTACAGATATACCAGTGAGGAT
GCCATCCTAAAACACAGGATGGATCACAGTGACTCCCAGTGGTTGGCAGACACTTGGCGTTCCA
CCTCTGGCTCTCGGGACCTCAGCAGCAGCAGCAGCCTCAGCAGTCGGCTGGGGGCGGATGCCCG
GGACCCACTAGACTGTCGTCGCTCCTTGCTCTCCTGGGACTCCCGAAGCCCCGGCGTGCCCCTG
CTTCCAGACACCAGCACTTTTTATGGCTCCCTCATCGCTGAGCTGCCCTCCAGTACCCCAGCCA
GGCCAAGTCCCCAGGTCCCAGCTGTCAGGCGCCTCCCACCCCAGCTGGCCCAGCTCTCCAGCCC
CTGTTTCAGCTCAGACAGCCTCTGCAGCCGCAGGGGACTCTCTTCTCCCCGCTTGTCTCTGGCC
CCTGCAGAGGCTTGGAAGGCCAAAAAGAAGCAGGAGCTGCAGCATGCCAACAGTTCCCCACTGC
TCCGGGGCAGCCACCCCTTGGAGCTCCGGGCCTGTGAGTTGGGAAATAGAGGTTCCAAGAACCT
TTCCCAAAGCCCAGGAGCTGTGCCCCAAGCTCTGGTTGCCTGGCGGGCCCTGGGACCGAAACTC
CTCAGCTCCTCAAATGAGCTGGTTACTCATCATCTCCCTCCAGCACCCCTCTTTCCTCATGAAA
CTCCCCCAACTCAGAGTCAACAGACCCAGCCTCCGGTGGCACCACAGGCTCCCTCCTCCATCCT
GCTGCCAGCAGCCCCCATCCCCATCCTTAGCCCCTGCAGTCCCCCTAGCCCCCAGGCCTCTTCC
CTCTCTGGCCCCAGCCCAGCTTCCAGTCGCCTGTCCAGCTCCTCCCTGTCATCCCTGGGGGAGG
ATCAAGACAGCGTGCTGACCCCTGAGGAGGTAGCCCTGTGCTTGGAACTCAGTGAGGGTGAGGA
GACTCCCAGGAACAGCGTCTCTCCCATGCCAAGGGCTCCTTCACCCCCCACCACCTATGGGTAC
ATCAGCGTCCCAACAGCCTCAGAGTTCACGGACATGGGCAGGACTGGAGGAGGGGTGGGGCCCG
AGGGGGGAGTCTTGCTGTGCCCACCTCGGCCCTGCCTCACCCCCACCCCCAGCGAGGGCTCCTT
AGCCAATGGTTGGGGCTCAGCCTCTGAGGACAATGCCGCCAGCGCCAGAGCCAGCCTTGTCAGC
TCCTCCGATGGCTCCTTCCTCGCTGATGCTCACTTTGCCCGGGCCCTGGCAGTGGCTGTGGATA
GCTTTGGTTTCGGTCTAGAGCCCAGGGAGGCAGACTGCGTCTTCATAGATGCCTCATCACCTCC
CTCCCCACGGGATGAGATCTTCCTGACCCCCAACCTCTCCCTGCCCCTGTGGGAGTGGAGGCCA
GACTGGTTGGAAGACATGGAGGTCAGCCACACCCAGTGGCTGGGAAGGGGGATGCCTCCCTGGC
CCCCTGACTCTCGGATCTCTTCCCAGAGAAGTCAGCTCCACTGTCGTATGCCCAAGGCTGGTGC
TTCTCCTGTAGATTACTCCTGAACCGTGTCCCTGAGACTTCCCAGACGGGAATCAGAACCACTT
CTCCTGTCCACCCACAAGACCTGGGCTGTGGTGTGTGGGTCTTGGCCTGTGTTTCTCTGCAGCT
GGGGTCCACCTTCCCAAGCCTCCAGAGAGTTCTCCCTCCACGATTGTGAAAACAAATGAAAACA
AAATTAGAGCAAAGCTGACCTGGAGCCCTCAGGGAGCAAAACATCATCTCCACCTGACTCCTAG
CCACTGCTTTCTCCTCTGTGCCATCCACTCCCACCACCAGGTCGTTTTGGCCTGAGGAGCAGCC
CTGCCTGCTGCTCTCCCCCCACCATTTGGATCACAGGAAGTGGAGGAGCCAGAGGTGCCTTTGT
GGAGGACAGCAGTGGCTGCTGGGAGAGGGCTGTGGAGGAAGGAGCTTCTCAGAGCCCCCTCTCA
GCCTTACCTGGGCCCCTCCTCTAGAGAAGAGCTCAACTCTCTCCCAACCTCACCATGGAAAGAA
AATAATTATGAATGCCACTGAGGCACTGAGGCCCTACCTCATGCCAAACAAAGGGTTCAAGGCT
GGGTCTAGCGAGGATGCTGAAGGAAGGGAGGTATGAGACCGTAGGTCAAAAGCACCATCCTCGT
ACTGTTGTCACTATGAGCTTAAGAAATTTGATACCATAAAATGGTAAAGACTTG

hide sequence

RefSeq Acc Id:

XM_003819931 ⟹ XP_003819979

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	9	125,579,458 - 125,593,113 (-)	NCBI
NHGRI_mPanPan1	11	126,684,362 - 126,697,989 (-)	NCBI
Mhudiblu_PPA_v0	11	119,711,023 - 119,724,686 (-)	NCBI
PanPan1.1	11	123,626,063 - 123,639,793 (-)	NCBI

Sequence:

show sequence

AAAGCCGCTTCCCTCCTGGGGCAGAGTCTCGGTCACAAACAACCACCACCGGCCCACCCCGCCC
CTCCTTCCCTCTTCACTGTGAGCTCAGAGCAGCAGGACAAAGTGCTCGGGACAAGGACATAGGG
CTGAGAGTAGCCATGGGCTCTGGAGGAGAGAGCCTCCTGGGGGGCAGGGGTTCCCTGCCTCTGC
TGCTCCTGCTCATCATGGCCCCCTGCCCGGGGACATGCCCACGATGGCCAGGCCCTGTCCACAG
ACCTGGGTGTCTACACATGTGAGGCCAGCAACCGGCTTGGCACGGCAGTCAGCAGAGGCGCTCG
GCTGTCTGTGGCTGTCCTCCGGGAGGATTTCCAGATCCAGCCTCGGGACATGGTGGCTGTGGTG
GGTGAGCAGTTTACTCTGGAATGTGGGCCGCCCTGGGGCCACCCAGAGCCCACAGTCTCATGGT
GGAAAGATGGGAAACCCCTGGTCCTCCAGCCCGGAAGGCACACAGTGTCCGGGGGGTCCCTGCT
GATGGCAAGAGCAGAGAAGAGTGATGAAGGGACCTACATGTGTGTGGCCACCAACAGCGCAGGA
CACAGGGAGAGCCGCGCAGCCCGGGTTTCCATCCAGGAGCCCCAGGACTACACGGAGCCTGTGG
AGCTTCTGGCTGTGCGAATTCAGCTGGAAAATGTGACACTGCTGAACCCGGATCCTGCAAAGGG
CCCCAAGCCTAGACCGGCGGTGTGGCTCAGCTGGAAGGTCAGTGGCCCTGCTGCGCCTGCCCAA
TCTTACACGGCCTTGTTCAGGACCCAGACTGCCCCGGGAGGCCAGGGAGCTCCGTGGGCAGAGG
AGCTGCTGGCCGGCTGGCAGAGCGCAGAGCTTGGAGGCCTCCACTGGGGCCAAGACTACGAGTT
CAAAGTGAGACCATCCTCTGGCCGGGCTCGAGGCCCTGACAGCAACGTGCTGCTCCTGAGGCTG
CCGGAAAAAGTGCCCAGTGCCCCACCTCAGGAGGTGACCCTAAAACCTGGCAATGGCAGTGTCT
TTGTGAGCTGGGTCCCACCACCTGCTGAAAACCACAATGGCATCATCCGTGGCTACCAGGTCTG
GAGCCTGGGCAACACGTCACTGCCACCAGCCAACTGGACTGTAGTTGGTGAGCAGACCCAGCTG
GAAATCGCCACCCATATGCCAGGCTCCTACTGCGTGCAAGTGGCTGCAGTCACTGGTGCTGGAG
CTGGGGAGCCCAGTAGACCTGTCTGCCTCCTTTTAGAGCAGGCCATGGAGCGAGCCACCCAAGA
ACCCAGTGAGCATGGTCCCTGGACCCTGGAGCAGCTGAGGGCTACCTTGAAGCGGCCTGAGGTC
ATTGCCACCTGCGGTGTTGCACTCTGGCTGCTGCTTCTGGGCACCGCTGTGTGTATCCACCGCC
GGCGCCGAGCTGGGGTGCACCTGGGCCCAGGTCTGTACAGATATACCAGTGAGGATGCCATCCT
AAAACACAGGATGGATCACAGTGACTCCCAGTGGTTGGCAGACACTTGGCGTTCCACCTCTGGC
TCTCGGGACCTCAGCAGCAGCAGCAGCCTCAGCAGTCGGCTGGGGGCGGATGCCCGGGACCCAC
TAGACTGTCGTCGCTCCTTGCTCTCCTGGGACTCCCGAAGCCCCGGCGTGCCCCTGCTTCCAGA
CACCAGCACTTTTTATGGCTCCCTCATCGCTGAGCTGCCCTCCAGTACCCCAGCCAGGCCAAGT
CCCCAGGTCCCAGCTGTCAGGCGCCTCCCACCCCAGCTGGCCCAGCTCTCCAGCCCCTGTTTCA
GCTCAGACAGCCTCTGCAGCCGCAGGGGACTCTCTTCTCCCCGCTTGTCTCTGGCCCCTGCAGA
GGCTTGGAAGGCCAAAAAGAAGCAGGAGCTGCAGCATGCCAACAGTTCCCCACTGCTCCGGGGC
AGCCACCCCTTGGAGCTCCGGGCCTGTGAGTTGGGAAATAGAGGTTCCAAGAACCTTTCCCAAA
GCCCAGGAGCTGTGCCCCAAGCTCTGGTTGCCTGGCGGGCCCTGGGACCGAAACTCCTCAGCTC
CTCAAATGAGCTGGTTACTCATCATCTCCCTCCAGCACCCCTCTTTCCTCATGAAACTCCCCCA
ACTCAGAGTCAACAGACCCAGCCTCCGGTGGCACCACAGGCTCCCTCCTCCATCCTGCTGCCAG
CAGCCCCCATCCCCATCCTTAGCCCCTGCAGTCCCCCTAGCCCCCAGGCCTCTTCCCTCTCTGG
CCCCAGCCCAGCTTCCAGTCGCCTGTCCAGCTCCTCCCTGTCATCCCTGGGGGAGGATCAAGAC
AGCGTGCTGACCCCTGAGGAGGTAGCCCTGTGCTTGGAACTCAGTGAGGGTGAGGAGACTCCCA
GGAACAGCGTCTCTCCCATGCCAAGGGCTCCTTCACCCCCCACCACCTATGGGTACATCAGCGT
CCCAACAGCCTCAGAGTTCACGGACATGGGCAGGACTGGAGGAGGGGTGGGGCCCGAGGGGGGA
GTCTTGCTGTGCCCACCTCGGCCCTGCCTCACCCCCACCCCCAGCGAGGGCTCCTTAGCCAATG
GTTGGGGCTCAGCCTCTGAGGACAATGCCGCCAGCGCCAGAGCCAGCCTTGTCAGCTCCTCCGA
TGGCTCCTTCCTCGCTGATGCTCACTTTGCCCGGGCCCTGGCAGTGGCTGTGGATAGCTTTGGT
TTCGGTCTAGAGCCCAGGGAGGCAGACTGCGTCTTCATAGATGCCTCATCACCTCCCTCCCCAC
GGGATGAGATCTTCCTGACCCCCAACCTCTCCCTGCCCCTGTGGGAGTGGAGGCCAGACTGGTT
GGAAGACATGGAGGTCAGCCACACCCAGTGGCTGGGAAGGGGGATGCCTCCCTGGCCCCCTGAC
TCTCGGATCTCTTCCCAGAGAAGTCAGCTCCACTGTCGTATGCCCAAGGCTGGTGCTTCTCCTG
TAGATTACTCCTGAACCGTGTCCCTGAGACTTCCCAGACGGGAATCAGAACCACTTCTCCTGTC
CACCCACAAGACCTGGGCTGTGGTGTGTGGGTCTTGGCCTGTGTTTCTCTGCAGCTGGGGTCCA
CCTTCCCAAGCCTCCAGAGAGTTCTCCCTCCACGATTGTGAAAACAAATGAAAACAAAATTAGA
GCAAAGCTGACCTGGAGCCCTCAGGGAGCAAAACATCATCTCCACCTGACTCCTAGCCACTGCT
TTCTCCTCTGTGCCATCCACTCCCACCACCAGGTCGTTTTGGCCTGAGGAGCAGCCCTGCCTGC
TGCTCTCCCCCCACCATTTGGATCACAGGAAGTGGAGGAGCCAGAGGTGCCTTTGTGGAGGACA
GCAGTGGCTGCTGGGAGAGGGCTGTGGAGGAAGGAGCTTCTCAGAGCCCCCTCTCAGCCTTACC
TGGGCCCCTCCTCTAGAGAAGAGCTCAACTCTCTCCCAACCTCACCATGGAAAGAAAATAATTA
TGAATGCCACTGAGGCACTGAGGCCCTACCTCATGCCAAACAAAGGGTTCAAGGCTGGGTCTAG
CGAGGATGCTGAAGGAAGGGAGGTATGAGACCGTAGGTCAAAAGCACCATCCTCGTACTGTTGT
CACTATGAGCTTAAGAAATTTGATACCATAAAATGGTAAAGACTTG

hide sequence

Protein Sequences


Protein RefSeqs	XP_003819978	(Get FASTA)	NCBI Sequence Viewer
	XP_003819979	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000004232.1

RefSeq Acc Id:

XP_003819979 ⟸ XM_003819931

- Peptide Label:

isoform X2

- Sequence:

show sequence

MVAVVGEQFTLECGPPWGHPEPTVSWWKDGKPLVLQPGRHTVSGGSLLMARAEKSDEGTYMCVA
TNSAGHRESRAARVSIQEPQDYTEPVELLAVRIQLENVTLLNPDPAKGPKPRPAVWLSWKVSGP
AAPAQSYTALFRTQTAPGGQGAPWAEELLAGWQSAELGGLHWGQDYEFKVRPSSGRARGPDSNV
LLLRLPEKVPSAPPQEVTLKPGNGSVFVSWVPPPAENHNGIIRGYQVWSLGNTSLPPANWTVVG
EQTQLEIATHMPGSYCVQVAAVTGAGAGEPSRPVCLLLEQAMERATQEPSEHGPWTLEQLRATL
KRPEVIATCGVALWLLLLGTAVCIHRRRRAGVHLGPGLYRYTSEDAILKHRMDHSDSQWLADTW
RSTSGSRDLSSSSSLSSRLGADARDPLDCRRSLLSWDSRSPGVPLLPDTSTFYGSLIAELPSST
PARPSPQVPAVRRLPPQLAQLSSPCFSSDSLCSRRGLSSPRLSLAPAEAWKAKKKQELQHANSS
PLLRGSHPLELRACELGNRGSKNLSQSPGAVPQALVAWRALGPKLLSSSNELVTHHLPPAPLFP
HETPPTQSQQTQPPVAPQAPSSILLPAAPIPILSPCSPPSPQASSLSGPSPASSRLSSSSLSSL
GEDQDSVLTPEEVALCLELSEGEETPRNSVSPMPRAPSPPTTYGYISVPTASEFTDMGRTGGGV
GPEGGVLLCPPRPCLTPTPSEGSLANGWGSASEDNAASARASLVSSSDGSFLADAHFARALAVA
VDSFGFGLEPREADCVFIDASSPPSPRDEIFLTPNLSLPLWEWRPDWLEDMEVSHTQWLGRGMP
PWPPDSRISSQRSQLHCRMPKAGASPVDYS

hide sequence

RefSeq Acc Id:	XP_003819978 ⟸ XM_003819930
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R8ZK46 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGSGGESLLGGRGSLPLLLLLIMGGMAQDSPPQILVHPQDQLFQGPGPARMSCRASGQPPPTIH WLLNGQPLSMVPPDPHHLLPDGTLLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGA RLSVAVLREDFQIQPRDMVAVVGEQFTLECGPPWGHPEPTVSWWKDGKPLVLQPGRHTVSGGSL LMARAEKSDEGTYMCVATNSAGHRESRAARVSIQEPQDYTEPVELLAVRIQLENVTLLNPDPAK GPKPRPAVWLSWKVSGPAAPAQSYTALFRTQTAPGGQGAPWAEELLAGWQSAELGGLHWGQDYE FKVRPSSGRARGPDSNVLLLRLPEKVPSAPPQEVTLKPGNGSVFVSWVPPPAENHNGIIRGYQV WSLGNTSLPPANWTVVGEQTQLEIATHMPGSYCVQVAAVTGAGAGEPSRPVCLLLEQAMERATQ EPSEHGPWTLEQLRATLKRPEVIATCGVALWLLLLGTAVCIHRRRRAGVHLGPGLYRYTSEDAI LKHRMDHSDSQWLADTWRSTSGSRDLSSSSSLSSRLGADARDPLDCRRSLLSWDSRSPGVPLLP DTSTFYGSLIAELPSSTPARPSPQVPAVRRLPPQLAQLSSPCFSSDSLCSRRGLSSPRLSLAPA EAWKAKKKQELQHANSSPLLRGSHPLELRACELGNRGSKNLSQSPGAVPQALVAWRALGPKLLS SSNELVTHHLPPAPLFPHETPPTQSQQTQPPVAPQAPSSILLPAAPIPILSPCSPPSPQASSLS GPSPASSRLSSSSLSSLGEDQDSVLTPEEVALCLELSEGEETPRNSVSPMPRAPSPPTTYGYIS VPTASEFTDMGRTGGGVGPEGGVLLCPPRPCLTPTPSEGSLANGWGSASEDNAASARASLVSSS DGSFLADAHFARALAVAVDSFGFGLEPREADCVFIDASSPPSPRDEIFLTPNLSLPLWEWRPDW LEDMEVSHTQWLGRGMPPWPPDSRISSQRSQLHCRMPKAGASPVDYS hide sequence

Ensembl Acc Id:

ENSPPAP00000004232 ⟸ ENSPPAT00000019642

Protein Domains

Fibronectin type-III Ig-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000017951	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000019642.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	FN3_dom	UniProtKB/TrEMBL
	FN3_sf	UniProtKB/TrEMBL
	Ig-like_dom	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_I-set	UniProtKB/TrEMBL
	Ig_sub	UniProtKB/TrEMBL
	Ig_sub2	UniProtKB/TrEMBL
KEGG Report	pps:100988251	UniProtKB/TrEMBL
NCBI Gene	ROBO4	ENTREZGENE
PANTHER	PROTEIN SIDEKICK	UniProtKB/TrEMBL
	PROTEIN SIDEKICK	UniProtKB/TrEMBL
Pfam	fn3	UniProtKB/TrEMBL
	I-set	UniProtKB/TrEMBL
	Ig_3	UniProtKB/TrEMBL
PROSITE	FN3	UniProtKB/TrEMBL
	IG_LIKE	UniProtKB/TrEMBL
SMART	FN3	UniProtKB/TrEMBL
	IGc2	UniProtKB/TrEMBL
	SM00409	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
	SSF49265	UniProtKB/TrEMBL
UniProt	A0A2R8ZK46	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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