ROBO4 (roundabout guidance receptor 4) - Rat Genome Database

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Gene: ROBO4 (roundabout guidance receptor 4) Sus scrofa
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Symbol: ROBO4
Name: roundabout guidance receptor 4
RGD ID: 14271909
Description: INVOLVED IN negative regulation of cell migration (ortholog); ASSOCIATED WITH aortic valve disease (ortholog); aortic valve disease 3 (ortholog); autistic disorder (ortholog); FOUND IN external side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: roundabout homolog 4; roundabout homolog 4, magic roundabout; roundabout, axon guidance receptor, homolog 4
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl952,083,008 - 52,097,744 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1952,083,757 - 52,097,784 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2957,599,263 - 57,613,277 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

Genomics

Comparative Map Data
ROBO4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl952,083,008 - 52,097,744 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1952,083,757 - 52,097,784 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2957,599,263 - 57,613,277 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ROBO4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl11124,883,691 - 124,898,500 (-)EnsemblGRCh38hg38GRCh38
GRCh3811124,883,691 - 124,897,865 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711124,753,587 - 124,767,761 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611124,259,324 - 124,272,950 (-)NCBINCBI36hg18NCBI36
Build 3411124,259,324 - 124,272,951NCBI
Celera11121,914,289 - 121,928,006 (-)NCBI
Cytogenetic Map11q24.2NCBI
HuRef11120,696,466 - 120,710,183 (-)NCBIHuRef
CHM1_111124,640,224 - 124,653,941 (-)NCBICHM1_1
Robo4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39937,313,198 - 37,325,319 (+)NCBIGRCm39mm39
GRCm39 Ensembl937,313,193 - 37,326,411 (+)Ensembl
GRCm38937,401,902 - 37,414,023 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl937,401,897 - 37,415,115 (+)EnsemblGRCm38mm10GRCm38
MGSCv37937,209,631 - 37,221,607 (+)NCBIGRCm37mm9NCBIm37
MGSCv36937,151,717 - 37,163,693 (+)NCBImm8
Celera934,616,424 - 34,628,396 (+)NCBICelera
Cytogenetic Map9A4NCBI
Robo4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0839,082,693 - 39,093,344 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl839,083,327 - 39,093,277 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0839,089,746 - 39,099,696 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4838,655,072 - 38,665,022 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1838,663,837 - 38,673,788 (+)NCBI
Celera837,322,941 - 37,332,891 (-)NCBICelera
Cytogenetic Map8q21NCBI
Robo4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541225,954,085 - 25,967,723 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541225,954,906 - 25,967,707 (-)NCBIChiLan1.0ChiLan1.0
ROBO4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.111123,626,063 - 123,639,793 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11123,626,063 - 123,639,837 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v011119,711,023 - 119,724,701 (-)NCBIMhudiblu_PPA_v0panPan3
ROBO4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.159,546,830 - 9,561,342 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl59,547,047 - 9,561,702 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha59,592,370 - 9,606,848 (+)NCBI
ROS_Cfam_1.059,486,652 - 9,501,126 (+)NCBI
UMICH_Zoey_3.159,559,307 - 9,573,796 (+)NCBI
UNSW_CanFamBas_1.059,529,769 - 9,544,248 (+)NCBI
UU_Cfam_GSD_1.059,566,647 - 9,580,690 (+)NCBI
Robo4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947107,074,254 - 107,089,138 (-)NCBI
SpeTri2.0NW_0049367431,321,816 - 1,336,682 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ROBO4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11116,027,516 - 116,041,771 (-)NCBI
ChlSab1.1 Ensembl1116,026,834 - 116,041,422 (-)Ensembl
Vero_WHO_p1.0NW_02366604310,076,903 - 10,090,940 (+)NCBI
Robo4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624927888,421 - 903,657 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium
Low 4 4 4 2 17 2 2
Below cutoff 6 3 1 6 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000016569   ⟹   ENSSSCP00000016125
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl952,083,008 - 52,097,739 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000073321   ⟹   ENSSSCP00000064783
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl952,090,001 - 52,097,744 (-)Ensembl
RefSeq Acc Id: XM_013979531   ⟹   XP_013834985
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1952,083,757 - 52,097,784 (-)NCBI
Sequence:
RefSeq Acc Id: XR_002335715
RefSeq Status:
Type: NON-CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1952,083,757 - 52,097,784 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013834985 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_013834985   ⟸   XM_013979531
- UniProtKB: F1S795 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000016125   ⟸   ENSSSCT00000016569
RefSeq Acc Id: ENSSSCP00000064783   ⟸   ENSSSCT00000073321
Protein Domains
Fibronectin type-III   Ig-like


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015203 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000016125 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000064783 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016569 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000073321 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
KEGG Report ssc:100524821 UniProtKB/TrEMBL
NCBI Gene ROBO4 ENTREZGENE
Pfam fn3 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
SMART FN3 UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
UniProt A0A5G2QJW4_PIG UniProtKB/TrEMBL
  F1S795 ENTREZGENE, UniProtKB/TrEMBL