Robo4 (roundabout guidance receptor 4)

Gene: Robo4 (roundabout guidance receptor 4) Chinchilla lanigera

Analyze

Symbol:

Robo4

Name:

roundabout guidance receptor 4

RGD ID:

8747064

Description:

ENCODES a protein that exhibits signaling receptor activity (ortholog); INVOLVED IN blood vessel endothelial cell migration (ortholog); establishment of endothelial barrier (ortholog); negative regulation of blood vessel endothelial cell migration (ortholog); ASSOCIATED WITH aortic aneurysm (ortholog); aortic valve disease 3 (ortholog); autistic disorder (ortholog); FOUND IN external side of plasma membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

roundabout homolog 4; roundabout, axon guidance receptor, homolog 4

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

ChiLan1.0 - Chinchilla ChiLan1.0 Assembly

Position:

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	25,954,085 - 25,967,723 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	25,954,906 - 25,967,707 (-)	NCBI	ChiLan1.0	ChiLan1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

aortic aneurysm (ISO)

aortic valve disease 3 (ISO)

autistic disorder (ISO)

bicuspid aortic valve disease (ISO)

Chromosome 11, Partial Trisomy 11q (ISO)

congenital diaphragmatic hernia (ISO)

Dwarfism (ISO)

genetic disease (ISO)

holoprosencephaly 11 (ISO)

Jacobsen Syndrome (ISO)

pre-eclampsia (ISO)

schizophrenia (ISO)

thoracic aortic aneurysm (ISO)

thyroid gland carcinoma (ISO)

transient cerebral ischemia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blood vessel endothelial cell migration (ISO)

establishment of endothelial barrier (ISO)

negative regulation of blood vessel endothelial cell migration (ISO)

Cellular Component

external side of plasma membrane (ISO)

Molecular Function

protein binding (ISO)

signaling receptor activity (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Transitive Annotation Pipeline	Automated assignment of GO, PW and RDO ISO annotations across species

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

Robo4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955412	25,954,085 - 25,967,723 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955412	25,954,906 - 25,967,707 (-)	NCBI	ChiLan1.0	ChiLan1.0

ROBO4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	124,883,691 - 124,897,865 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	124,883,691 - 124,898,500 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	124,753,587 - 124,767,761 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	124,259,324 - 124,272,950 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	124,259,324 - 124,272,951	NCBI
Celera	11	121,914,289 - 121,928,006 (-)	NCBI		Celera
Cytogenetic Map	11	q24.2	NCBI
HuRef	11	120,696,466 - 120,710,183 (-)	NCBI		HuRef
CHM1_1	11	124,640,224 - 124,653,941 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	124,912,311 - 124,926,485 (-)	NCBI		T2T-CHM13v2.0

Robo4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	37,313,198 - 37,325,319 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	37,313,193 - 37,326,411 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	37,401,902 - 37,414,023 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	37,401,897 - 37,415,115 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	37,209,631 - 37,221,607 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	37,151,717 - 37,163,693 (+)	NCBI		MGSCv36	mm8
Celera	9	34,616,424 - 34,628,396 (+)	NCBI		Celera
Cytogenetic Map	9	A4	NCBI
cM Map	9	20.76	NCBI

Robo4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	45,308,739 - 45,322,522 (+)	NCBI		GRCr8
mRatBN7.2	8	37,119,953 - 37,133,887 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	37,119,988 - 37,132,519 (+)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	8	39,878,900 - 39,891,485 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	39,878,955 - 39,890,942 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	39,879,806 - 39,892,371 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Cytogenetic Map	8	q22	NCBI

ROBO4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	125,579,458 - 125,593,121 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	126,684,362 - 126,697,997 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	119,711,023 - 119,724,701 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	123,626,063 - 123,639,793 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	123,626,063 - 123,639,837 (-)	Ensembl	panpan1.1		panPan2

ROBO4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	9,546,830 - 9,561,342 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	9,547,047 - 9,561,702 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	9,592,370 - 9,606,848 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	9,486,652 - 9,501,126 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	9,486,825 - 9,501,122 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	9,559,307 - 9,573,796 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	9,529,769 - 9,544,248 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	9,566,647 - 9,580,690 (+)	NCBI		UU_Cfam_GSD_1.0

Robo4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	107,074,254 - 107,089,138 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936743	1,318,718 - 1,336,689 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936743	1,321,816 - 1,336,682 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ROBO4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	52,083,760 - 52,097,736 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	52,083,757 - 52,097,784 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	57,599,263 - 57,613,277 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ROBO4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	116,027,516 - 116,041,771 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	116,026,834 - 116,041,422 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	10,076,903 - 10,090,940 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Robo4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624927	888,141 - 903,659 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624927	888,421 - 903,657 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_013511214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_013511216	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001232921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AGCD01013180	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GBDK01075226	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSCLAT00000024853 ⟹ ENSCLAP00000024615

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955412	25,954,085 - 25,967,723 (-)	Ensembl

RefSeq Acc Id:

ENSCLAT00000024854 ⟹ ENSCLAP00000024616

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955412	25,954,085 - 25,967,723 (-)	Ensembl

RefSeq Acc Id:

ENSCLAT00000024855 ⟹ ENSCLAP00000024617

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0 Ensembl	NW_004955412	25,958,970 - 25,966,914 (-)	Ensembl

RefSeq Acc Id:

XM_013511214 ⟹ XP_013366668

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955412	25,954,906 - 25,967,707 (-)	NCBI

Sequence:

show sequence

CCTACCCGCCCCTCCTTCCCTCACTGCGGTAACTCGGAGCAGCAGGACAAAGCGCCTGGGATAA
GGACTGAAGACTGAAGCAGCCATGGGCTCTGAAGGAGTGGGCCTCCCTGGGGGCAGGTGGGCCC
TGCTTCTCCTGTTTCTGTTGGCTGTGGGAGGCATGGCTCAGGAGTCCCCACCCCAGATCTTAGT
TCACCCCCAGGACCAGCTGCTCCAGGGCTCGGGCTCTGCCAAGATGAGCTGCAGCGCATCAGGC
CGGCCACCCCCCACCATCCGCTGGCTGCTGAATGGGCAGCCCCTGAAGGTAGATGTAGACCTAT
ACCACCTCTTGTCCGATGGAAGCCTCCTCCTGCTGCGGCCCCCCATGCAGGGACGAGCCCAGAA
TGACCAGGCCCTGTCTGCAATCCTGGGCATCTACACGTGTGAGGCCAGCAACCAGCTGGGCACG
GCAGTCAGCAGAGGCGCTCGGCTGTCTGTGGCTGTCCTCCGAGAGGATTTCCAGATCCAGCCCC
AAGACACGGTGGCCATGGTGGGTGAGCAGGTGATTCTGGAGTGTGGGCCTCCCTGGGGCTACCC
AGAACCCACAGTCTCATGGTGGAAAGATGGGAAACCCCTGGCCCTTCAGCCGGGGCGGCACACG
GTATCCAGTGGTTCCCTGCTGGTGTCAAGTGCAGAGAAGAGTGACACGGGGATCTATATGTGTG
CAGCTGCCAACAATGCGGGACAGCGCGAAAGTCGAGCAGCCAGGGTCTCTATCCAGGAGTCCCA
AGACCACAAGGAACCTCTGGAGCTTCTGGCTGTACGCATTCAGCTAAAAAATGTGACCCTGCTG
AACCTAGACTCCAAGAAGGGCCCCAAGCCTGGGCCAGCTGTGTGGCTCAGCTGGAAGGTGAGTG
GCCCTGCTGCACCTGCTCAGTCCTACACAGCTTTGTTCAGGGCCCAGACAGCCCAGGGAGACCA
GAGAGCTCCGTGGGCAGAGGTGCTGCTGGACGGCTGGCAAAGTGCAGAGCTCAGCGGACTCCAC
TGGGGCCAAGCCTACGAGTTCAAAGTGAGACCATCCTCTGGCCGGGCTCGAGGCCCTGACAGCA
ATGTGTTGCTCCTGAGCCTGCCAGAACAAGTACCCAGTGCCCCACCCCAAGAAGTGACCCTAAA
ACATGACAACAGCAGCATCCTTGTGAGCTGGGTCCCACCACCTGCTGAAAACCACAATGGCATC
ATTCGTGGCTACCAGGTCTGGAGCTTGGGCAACAGCTCATTGCCTCCCATCAACTACACTGTCA
TGGGTGTGCAGACCCAGCTGGAGATCGATACCCGAACATCAGGTTCCTACTGTGTCCAAGTGGC
TGCGTTCACTGGGGCTGGGACTGGGGAACCCAGTAGCCCTGTCTGCCTCCTGTTAGAGCAAGCC
ATGGAGCGATCAGCCCAAGAACCCAGTGAGCATGGTCTCTGGACCTTGGAGTGGCTGAGGGCCA
CCGTGAGGAGGCCAGAGGTCATCACCAGTGGAGGCGTCCTCCTTTGGCTGCTGCTGCTGGGCAT
CACTGTGTGTGTCTACCGCAGGCGCCGAGCCAGGGTGCACATGGGCCCAGGGCTATACAGATAC
ACCAGTGAGGATGCCATCTTAAAACACAGGATGGACCACAGTGACTCTCCCTGGCTGGCAGACA
CCTGGAGATCCACCTCTGGCTCTCGGGACTTGAGCAGTAGCAGCAGCCTTAACAGCCGGCTGGG
AGTGGACCCCCGGGACCCGCTAGACTGCCGGCGCTCCTTGATCTCCTGGGACCCCCGAAGCCCC
GGGGTGCCCCTGCTTCCAGACACCAGCACCTTTTATGGCTCCCTCATTGCTGAGCTGCCCTCCA
GCCCCCCAGCCCAGCCAAGCCCCCAGGCCCCAGCTGCCAGGCGCCTTCCTCCCCCATTGGTGCG
GACCTCCAGCCCCTGGCCCAGCTCAGACAGCCTCTGCAGCCGCAGGGGCCTCGCTTCGCCCCGC
TTGTCTCTGGCCCCTGCAGAGGCTTGGAAGGCCAAGAAGAAGCAAGAACTGCACCAAGCCAACA
GCTCTCCCCTGCTCCGGGGTAGCCACCCACTGGAGCTCTGGGCCTGGGAGTTGGGACACAGAAG
CTCCAAGAACCTTTCCCAAAGCCCAGGCCCAGGCTCTTGTTTCCCAGCAGCTGTGCCTGGGGCT
CTGGTGGCCTGGCGGGCCCTGGGACCACAGCTCCTCCGTAACTCCAATGAGCTAGCGACCCGCC
CTCTCCCTCCAGTTCCTCTCTCTCCAGGCGGAACCCACACTCAGAGTCCACAGACCCAGCACTC
CGTGGAACCCCAGGCTTCTGCTCCCCTCCCCGTCCTTAGCCCCTCCAGGTCTCCCAGCCCCCAG
CCCTCGTCCCTCTCTGGTCCCAGCCCAGCTTCCAGCCGCCTGTCCAGCTCTTCACTGTCATCCC
TGGGGGAGGATCAGGACAGTGTGCTGACCCCTGAGGAGGTGGCCTTGTGCCTGGAACTCAGTGA
GGGCGAGGAGACCCCCAGGAACAGCATCTCTCCTATGCCCAGGGCGCCTTCGCCCCCTACAACC
TATGGGTACATCAGCATTCCAACAGCCTCGGAGCTGGCAGATGTGGGCAGGGCTGGAGGAGGCG
TGGCATCTGAAGGGGGGGGCTTGTTGTGCCCACCTCGGCCCTGCCCCACCCCTACCCCCAGTGA
GGGCTCCCTGGCCAATGGCTGGGGCTCGGCCTCTGAGGACAACGCGCCCAGTGCCAGAGCCAGC
CTGGTCAGCTCTTCTGATGGCTCTTTCCTCGCTGATGCTCACTTTGCCCGTGCCCTGGGCATGG
CTGTGGATAGCTTTGGTTTTGGTCTGGAGCCCCGGGAGGCCGACTGCGTTTTCACTGACGTCTC
ATCACCTCCCTCCCCACGGGATGACATCTTCCTGACGCCCACCCTTTCCCTGCCCCTATGGGAG
TGGAGGCCAGACTGGTTGGAGGACATAGAGGTCAACTACACCCAGCAGCTGGGAAGGGGGCTGC
CTCCTTGGACCCCTGACTCTGGGATCTCTTCCCAGTGAAGTCGGCTCAGCTGTCCTGAACCCAA
GGCTGGGGATTCCTCCTGAACTGTGAGTCTGAGATAGACAGCAGGACCTCGGGGCCAGCCCTCC
TGTGTGCTCACAAGGCTGGCCTGTGCCTCCAGGAGAGTTTTCCCACCAACATTGCTCAAAGAAA
GAAAAAAGATGAAAGCAAGAGCAAAGTAGACCTGGAGCATTCTGCATGCAAAGCATCACCTCCA
CCTGACCCCAGGATCCTCTCTCCTCAGAGCCACCCTTCAGCCTGGGCCTCTGGCCTCAGGAGCA
GCTCTGTCTCCTGCTCTTCCCCCCCAGGGGTCACAAGAAGTGGGGAGCCAGAGGGCTCTCCACA
GAGGACCCAGTGGCTGGTCAAGAGGGCTGTGGAAGCAGAGCGCCTCCTCTCTCAGCCCTACCTG
GGCCCCTCCTCTAGAGGCCAGTGCAAACCTCTCCCCGGCCCCATCACATAGAGAAAATAAAGCA
GCGGCACTGGGGCCCTACCTAGTGCCAAGGCCCAGGGCTCAAGGATGGGTCTAGGGAAGAGACT
GAACAAAGAGATGAGCGAGCATGGGACAAAAGCACCCTCCTCATCCCACTGTCACTTTGAGCTT
CTGAAACTTGATGCTATAAAACTGTAAAGACTTGA

hide sequence

RefSeq Acc Id:

XM_013511216 ⟹ XP_013366670

Type:

CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955412	25,954,906 - 25,967,707 (-)	NCBI

Sequence:

show sequence

CCTACCCGCCCCTCCTTCCCTCACTGCGGTAACTCGGAGCAGCAGGACAAAGCGCCTGGGATAA
GGACTGAAGACTGAAGCAGCCATGGGCTCTGAAGGAGTGGGCCTCCCTGGGGGCAGGTGGGCCC
TGCTTCTCCTGTTTCTGTTGGCTGTGGGAGGCATGGCTCAGGAGTCCCCACCCCAGATCTTAGT
TCACCCCCAGGACCAGCTGCTCCAGGGCTCGGGCTCTGCCAAGATGAGCTGCAGCGCATCAGGC
CGGCCACCCCCCACCATCCGCTGGCTGCTGAATGGGCAGCCCCTGAAGGTAGATGTAGACCTAT
ACCACCTCTTGTCCGATGGAAGCCTCCTCCTGCTGCGGCCCCCCATGCAGGGACGAGCCCAGAA
TGACCAGGCCCTGTCTGCAATCCTGGGCATCTACACGTGTGAGGCCAGCAACCAGCTGGGCACG
GCAGTCAGCAGAGGCGCTCGGCTGTCTGTGGCTGTCCTCCGAGAGGATTTCCAGATCCAGCCCC
AAGACACGGTGGCCATGGTGGGTGAGCAGGTGATTCTGGAGTGTGGGCCTCCCTGGGGCTACCC
AGAACCCACAGTCTCATGGTGGAAAGATGGGAAACCCCTGGCCCTTCAGCCGGGGCGGCACACG
GTATCCAGTGGTTCCCTGCTGGTGTCAAGTGCAGAGAAGAGTGACACGGGGATCTATATGTGTG
CAGCTGCCAACAATGCGGGACAGCGCGAAAGTCGAGCAGCCAGGGTCTCTATCCAGGAGTCCCA
AGACCACAAGGAACCTCTGGAGCTTCTGGCTGTACGCATTCAGCTAAAAAATGTGACCCTGCTG
AACCTAGACTCCAAGAAGGGCCCCAAGCCTGGGCCAGCTGTGTGGCTCAGCTGGAAGGTGAGTG
GCCCTGCTGCACCTGCTCAGTCCTACACAGCTTTGTTCAGGGCCCAGACAGCCCAGGGAGACCA
GAGAGCTCCGTGGGCAGAGGTGCTGCTGGACGGCTGGCAAAGTGCAGAGCTCAGCGGACTCCAC
TGGGGCCAAGCCTACGAGTTCAAAGTGAGACCATCCTCTGGCCGGGCTCGAGGCCCTGACAGCA
ATGTGTTGCTCCTGAGCCTGCCAGAACAAGTACCCAGTGCCCCACCCCAAGAAGTGACCCTAAA
ACATGACAACAGCAGCATCCTTGTGAGCTGGGTCCCACCACCTGCTGAAAACCACAATGGCATC
ATTCGTGGCTACCAGGTCTGGAGCTTGGGCAACAGCTCATTGCCTCCCATCAACTACACTGTCA
TGGGTGTGCAGACCCAGCTGGAGATCGATACCCGAACATCAGGTTCCTACTGTGTCCAAGTGGC
TGCGTTCACTGGGGCTGGGACTGGGGAACCCAGTAGCCCTGTCTGCCTCCTGTTAGAGCAAGCC
ATGGAGCGATCAGCCCAAGAACCCAGTGAGCATGGTCTCTGGACCTTGGAGTGGCTGAGGGCCA
CCGTGAGGAGGCCAGAGGTCATCACCAGTGGAGGCGTCCTCCTTTGGCTGCTGCTGCTGGGCAT
CACTGTGTGTGTCTACCGCAGGCGCCGAGCCAGGGTGCACATGGGCCCAGGGCTATACAGATAC
ACCAGTGAGGATGCCATCTTAAAACACAGGATGGACCACAGTGACTCTCCCTGGCTGGCAGACA
CCTGGAGATCCACCTCTGGCTCTCGGGACTTGAGCAGTAGCAGCAGCCTTAACAGCCGGCTGGG
AGTGGACCCCCGGGACCCGCTAGACTGCCGGCGCTCCTTGATCTCCTGGGACCCCCGAAGCCCC
GGGGTGCCCCTGCTTCCAGACACCAGCACCTTTTATGGCTCCCTCATTGCTGAGCTGCCCTCCA
GCCCCCCAGCCCAGCCAAGCCCCCAGGCCCCAGCTGCCAGGCGCCTTCCTCCCCCATTGGTGCG
GACCTCCAGCCCCTGGCCCAGCTCAGACAGCCTCTGCAGCCGCAGGGGCCTCGCTTCGCCCCGC
TTGTCTCTGGCCCCTGCAGAGGCTTGGAAGGCCAAGAAGAAGCAAGAACTGCACCAAGCCAACA
GCTCTCCCCTGCTCCGGGGTAGCCACCCACTGGAGCTCTGGGCCTGGGAGTTGGGACACAGAAG
CTCCAAGAACCTTTCCCAAAGCCCAGCAGCTGTGCCTGGGGCTCTGGTGGCCTGGCGGGCCCTG
GGACCACAGCTCCTCCGTAACTCCAATGAGCTAGCGACCCGCCCTCTCCCTCCAGTTCCTCTCT
CTCCAGGCGGAACCCACACTCAGAGTCCACAGACCCAGCACTCCGTGGAACCCCAGGCTTCTGC
TCCCCTCCCCGTCCTTAGCCCCTCCAGGTCTCCCAGCCCCCAGCCCTCGTCCCTCTCTGGTCCC
AGCCCAGCTTCCAGCCGCCTGTCCAGCTCTTCACTGTCATCCCTGGGGGAGGATCAGGACAGTG
TGCTGACCCCTGAGGAGGTGGCCTTGTGCCTGGAACTCAGTGAGGGCGAGGAGACCCCCAGGAA
CAGCATCTCTCCTATGCCCAGGGCGCCTTCGCCCCCTACAACCTATGGGTACATCAGCATTCCA
ACAGCCTCGGAGCTGGCAGATGTGGGCAGGGCTGGAGGAGGCGTGGCATCTGAAGGGGGGGGCT
TGTTGTGCCCACCTCGGCCCTGCCCCACCCCTACCCCCAGTGAGGGCTCCCTGGCCAATGGCTG
GGGCTCGGCCTCTGAGGACAACGCGCCCAGTGCCAGAGCCAGCCTGGTCAGCTCTTCTGATGGC
TCTTTCCTCGCTGATGCTCACTTTGCCCGTGCCCTGGGCATGGCTGTGGATAGCTTTGGTTTTG
GTCTGGAGCCCCGGGAGGCCGACTGCGTTTTCACTGACGTCTCATCACCTCCCTCCCCACGGGA
TGACATCTTCCTGACGCCCACCCTTTCCCTGCCCCTATGGGAGTGGAGGCCAGACTGGTTGGAG
GACATAGAGGTCAACTACACCCAGCAGCTGGGAAGGGGGCTGCCTCCTTGGACCCCTGACTCTG
GGATCTCTTCCCAGTGAAGTCGGCTCAGCTGTCCTGAACCCAAGGCTGGGGATTCCTCCTGAAC
TGTGAGTCTGAGATAGACAGCAGGACCTCGGGGCCAGCCCTCCTGTGTGCTCACAAGGCTGGCC
TGTGCCTCCAGGAGAGTTTTCCCACCAACATTGCTCAAAGAAAGAAAAAAGATGAAAGCAAGAG
CAAAGTAGACCTGGAGCATTCTGCATGCAAAGCATCACCTCCACCTGACCCCAGGATCCTCTCT
CCTCAGAGCCACCCTTCAGCCTGGGCCTCTGGCCTCAGGAGCAGCTCTGTCTCCTGCTCTTCCC
CCCCAGGGGTCACAAGAAGTGGGGAGCCAGAGGGCTCTCCACAGAGGACCCAGTGGCTGGTCAA
GAGGGCTGTGGAAGCAGAGCGCCTCCTCTCTCAGCCCTACCTGGGCCCCTCCTCTAGAGGCCAG
TGCAAACCTCTCCCCGGCCCCATCACATAGAGAAAATAAAGCAGCGGCACTGGGGCCCTACCTA
GTGCCAAGGCCCAGGGCTCAAGGATGGGTCTAGGGAAGAGACTGAACAAAGAGATGAGCGAGCA
TGGGACAAAAGCACCCTCCTCATCCCACTGTCACTTTGAGCTTCTGAAACTTGATGCTATAAAA
CTGTAAAGACTTGA

hide sequence

RefSeq Acc Id:

XR_001232921

Type:

NON-CODING

Position:

Chinchilla Assembly	Chr	Position (strand)	Source
ChiLan1.0	NW_004955412	25,954,906 - 25,967,707 (-)	NCBI

Sequence:

show sequence

CCTACCCGCCCCTCCTTCCCTCACTGCGGTAACTCGGAGCAGCAGGACAAAGCGCCTGGGATAA
GGACTGAAGACTGAAGCAGCCATGGGCTCTGAAGGAGTGGGCCTCCCTGGGGGCAGGTGGGCCC
TGCTTCTCCTGTTTCTGTTGGCTGTGGGAGGCATGGCTCAGGAGTCCCCACCCCAGATCTTAGT
TCACCCCCAGGACCAGCTGCTCCAGGGCTCGGGCTCTGCCAAGATGAGCTGCAGCGCATCAGGC
CGGCCACCCCCCACCATCCGCTGGCTGCTGAATGGGCAGCCCCTGAAGGTAGATGTAGACCTAT
ACCACCTCTTGTCCGATGGAAGCCTCCTCCTGCTGCGGCCCCCCATGCAGGGACGAGCCCAGAA
TGACCAGGCCCTGTCTGCAATCCTGGGCATCTACACGTGTGAGGCCAGCAACCAGCTGGGCACG
GCAGTCAGCAGAGGCGCTCGGCTGTCTGTGGCTGTCCTCCGAGAGGATTTCCAGATCCAGCCCC
AAGACACGGTGGCCATGGTGGGTGAGCAGGTGATTCTGGAGTGTGGGCCTCCCTGGGGCTACCC
AGAACCCACAGTCTCATGGTGGAAAGATGGGAAACCCCTGGCCCTTCAGCCGGGGCGGCACACG
GTATCCAGTGGTTCCCTGCTGGTGTCAAGTGCAGAGAAGAGTGACACGGGGATCTATATGTGTG
CAGCTGCCAACAATGCGGGACAGCGCGAAAGTCGAGCAGCCAGGGTCTCTATCCAGGAGTCCCA
AGACCACAAGGAACCTCTGGAGCTTCTGGCTGTACGCATTCAGCTAAAAAATGTGACCCTGCTG
AACCTAGACTCCAAGAAGGGCCCCAAGCCTGGGCCAGCTGTGTGGCTCAGCTGGAAGGTGAGTG
GCCCTGCTGCACCTGCTCAGTCCTACACAGCTTTGTTCAGGGCCCAGACAGCCCAGGGAGACCA
GAGAGCTCCGTGGGCAGAGGTGCTGCTGGACGGCTGGCAAAGTGCAGAGCTCAGCGGACTCCAC
TGGGGCCAAGCCTACGAGTTCAAAGTGAGACCATCCTCTGGCCGGGCTCGAGGCCCTGACAGCA
ATGTGTTGCTCCTGAGCCTGCCAGAACAAGTACCCAGTGCCCCACCCCAAGAAGTGACCCTAAA
ACATGACAACAGCAGCATCCTTGTGAGCTGGGTCCCACCACCTGCTGAAAACCACAATGGCATC
ATTCGTGGCTACCAGGTCTGGAGCTTGGGCAACAGCTCATTGCCTCCCATCAACTACACTGTCA
TGGGTGTGCAGACCCAGCTGGAGATCGATACCCGAACATCAGGTTCCTACTGTGTCCAAGTGGC
TGCGTTCACTGGGGCTGGGACTGGGGAACCCAGTAGCCCTGTCTGCCTCCTGTTAGAGCAAGCC
ATGGAGCGATCAGCCCAAGAACCCAGTGAGCATGGTCTCTGGACCTTGGAGTGGCTGAGGGCCA
CCGTGAGGAGGCCAGAGGTCATCACCAGTGGAGGCGTCCTCCTTTGGCTGCTGCTGCTGGGCAT
CACTGTGTGTGTCTACCGCAGGCGCCGAGCCAGGGTGCACATGGGCCCAGGGCTATACAGATAC
ACCAGTGAGGATGCCATCTTAAAACACAGGATGGACCACAGTGACTCTCCCTGGCTGGCAGACA
CCTGGAGATCCACCTCTGGCTCTCGGGACTTGAGCAGTAGCAGCAGCCTTAACAGCCGGCTGGG
AGTGGACCCCCGGGACCCGCTAGACTGCCGGCGCTCCTTGATCTCCTGGGACCCCCGAAGCCCC
GGGGTGCCCCTGCTTCCAGACACCAGCACCTTTTATGGCTCCCTCATTGCTGAGCTGCCCTCCA
GCCCCCCAGCCCAGCCAAGCCCCCAGGCCCCAGCTGCCAGGCGCCTTCCTCCCCCATTGGTGCG
GACCTCCAGCCCCTGGCCCAGCTCAGACAGCCTCTGCAGCCGCAGGGGCCTCGCTTCGCCCCGC
TTGTCTCTGGCCCCTGCAGAGGCTTGGAAGGCCAAGAAGAAGCAAGAACTGCACCAAGCCAACA
GCTCTCCCCTGCTCCGGGGTAGCCACCCACTGGAGCTCTGGGCCTGGGAGTTGGGACACAGAAG
CTCCAAGAACCTTTCCCAAAGCCCAGGCCCAGGCTCTTGTTTCCCAGCAGCTGTGCCTGGGGCT
CTGGTGGCCTGGCGGGCCCTGGGACCACAGCTCCTCCGTAACTCCAATGAGCTAGCGACCCGCC
CTCTCCCTCCAGTTCCTCTCTCTCCAGGCGGAACCCACACTCAGAGTCCACAGACCCAGCACTC
CGTGGAACCCCAGGCTTCTGCTCCCCTCCCCGTCCTTAGCCCCTCCAGGTCTCCCAGCCCCCAG
CCCTCGTCCCTCTCTGGTCCCAGCCCAGCTTCCAGCCGCCTGTCCAGCTCTTCACTGTCATCCC
TGGGGGAGGATCAGGACAGTGTGCTGACCCCTGAGGAGGTGGCCTTGTGCCTGGAACTCAGTGA
GGGCGAGGAGACCCCCAGGAACAGCATCTCTCCTATGCCCAGGGCGCCTTCGCCCCCTACAACC
TATGGGTACATCAGCATTCCAACAGCCTCGGAGCTGGCAGATGTGGGCAGGGCTGGAGGAGGCG
TGGCATCTGAAGGGGGGGGCTTGTTGTGCCCACCTCGGCCCTGCCCCACCCCTACCCCCAGTGA
GGGCTCCCTGGCCAATGGCTGGGGCTCGGCCTCTGAGGACAACGCGCCCAGTGCCAGAGCCAGC
CTGGTCAGCTCTTCTGATGGCTCTTTCCTCGCTGATGCTCACTTTGCCCGTGCCCTGGGCATGG
CTGTGGATAGCTTTGGTTTTGGTCTGGAGCCCCGGGAGGCCGACTGCGTTTTCACTGACGTCTC
ATCACCTCCCTCCCCACGGGATGACATCTTCCTGACGCCCACCCTTTCCCTGCCCCTATGGGAG
TGGAGGCCAGACTGGTTGGAGGACATAGAGGTCAACTACACCCAGCAGCTGGGAAGGGGGCTGC
CTCCTTGGACCCCTGACTCTGGGATCTCTTCCCAGTGAAGTCGGCTCAGCTGTCCTGAACCCAA
GGCTGGGGGTGAGTGTGTGGCTGTCTGGCTAACACGATTCCTCCTGAACTGTGAGTCTGAGATA
GACAGCAGGACCTCGGGGCCAGCCCTCCTGTGTGCTCACAAGGCTGGCCTGTGCCTCCAGGAGA
GTTTTCCCACCAACATTGCTCAAAGAAAGAAAAAAGATGAAAGCAAGAGCAAAGTAGACCTGGA
GCATTCTGCATGCAAAGCATCACCTCCACCTGACCCCAGGATCCTCTCTCCTCAGAGCCACCCT
TCAGCCTGGGCCTCTGGCCTCAGGAGCAGCTCTGTCTCCTGCTCTTCCCCCCCAGGGGTCACAA
GAAGTGGGGAGCCAGAGGGCTCTCCACAGAGGACCCAGTGGCTGGTCAAGAGGGCTGTGGAAGC
AGAGCGCCTCCTCTCTCAGCCCTACCTGGGCCCCTCCTCTAGAGGCCAGTGCAAACCTCTCCCC
GGCCCCATCACATAGAGAAAATAAAGCAGCGGCACTGGGGCCCTACCTAGTGCCAAGGCCCAGG
GCTCAAGGATGGGTCTAGGGAAGAGACTGAACAAAGAGATGAGCGAGCATGGGACAAAAGCACC
CTCCTCATCCCACTGTCACTTTGAGCTTCTGAAACTTGATGCTATAAAACTGTAAAGACTTGA

hide sequence

Protein Sequences


Protein RefSeqs	XP_013366668	(Get FASTA)	NCBI Sequence Viewer
	XP_013366670	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCLAP00000024615.1
	ENSCLAP00000024616
	ENSCLAP00000024616.1
	ENSCLAP00000024617
	ENSCLAP00000024617.1

RefSeq Acc Id:	XP_013366670 ⟸ XM_013511216
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C2W3F9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGSEGVGLPGGRWALLLLFLLAVGGMAQESPPQILVHPQDQLLQGSGSAKMSCSASGRPPPTIR WLLNGQPLKVDVDLYHLLSDGSLLLLRPPMQGRAQNDQALSAILGIYTCEASNQLGTAVSRGAR LSVAVLREDFQIQPQDTVAMVGEQVILECGPPWGYPEPTVSWWKDGKPLALQPGRHTVSSGSLL VSSAEKSDTGIYMCAAANNAGQRESRAARVSIQESQDHKEPLELLAVRIQLKNVTLLNLDSKKG PKPGPAVWLSWKVSGPAAPAQSYTALFRAQTAQGDQRAPWAEVLLDGWQSAELSGLHWGQAYEF KVRPSSGRARGPDSNVLLLSLPEQVPSAPPQEVTLKHDNSSILVSWVPPPAENHNGIIRGYQVW SLGNSSLPPINYTVMGVQTQLEIDTRTSGSYCVQVAAFTGAGTGEPSSPVCLLLEQAMERSAQE PSEHGLWTLEWLRATVRRPEVITSGGVLLWLLLLGITVCVYRRRRARVHMGPGLYRYTSEDAIL KHRMDHSDSPWLADTWRSTSGSRDLSSSSSLNSRLGVDPRDPLDCRRSLISWDPRSPGVPLLPD TSTFYGSLIAELPSSPPAQPSPQAPAARRLPPPLVRTSSPWPSSDSLCSRRGLASPRLSLAPAE AWKAKKKQELHQANSSPLLRGSHPLELWAWELGHRSSKNLSQSPAAVPGALVAWRALGPQLLRN SNELATRPLPPVPLSPGGTHTQSPQTQHSVEPQASAPLPVLSPSRSPSPQPSSLSGPSPASSRL SSSSLSSLGEDQDSVLTPEEVALCLELSEGEETPRNSISPMPRAPSPPTTYGYISIPTASELAD VGRAGGGVASEGGGLLCPPRPCPTPTPSEGSLANGWGSASEDNAPSARASLVSSSDGSFLADAH FARALGMAVDSFGFGLEPREADCVFTDVSSPPSPRDDIFLTPTLSLPLWEWRPDWLEDIEVNYT QQLGRGLPPWTPDSGISSQ hide sequence

RefSeq Acc Id:	XP_013366668 ⟸ XM_013511214
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C2W3F9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGSEGVGLPGGRWALLLLFLLAVGGMAQESPPQILVHPQDQLLQGSGSAKMSCSASGRPPPTIR WLLNGQPLKVDVDLYHLLSDGSLLLLRPPMQGRAQNDQALSAILGIYTCEASNQLGTAVSRGAR LSVAVLREDFQIQPQDTVAMVGEQVILECGPPWGYPEPTVSWWKDGKPLALQPGRHTVSSGSLL VSSAEKSDTGIYMCAAANNAGQRESRAARVSIQESQDHKEPLELLAVRIQLKNVTLLNLDSKKG PKPGPAVWLSWKVSGPAAPAQSYTALFRAQTAQGDQRAPWAEVLLDGWQSAELSGLHWGQAYEF KVRPSSGRARGPDSNVLLLSLPEQVPSAPPQEVTLKHDNSSILVSWVPPPAENHNGIIRGYQVW SLGNSSLPPINYTVMGVQTQLEIDTRTSGSYCVQVAAFTGAGTGEPSSPVCLLLEQAMERSAQE PSEHGLWTLEWLRATVRRPEVITSGGVLLWLLLLGITVCVYRRRRARVHMGPGLYRYTSEDAIL KHRMDHSDSPWLADTWRSTSGSRDLSSSSSLNSRLGVDPRDPLDCRRSLISWDPRSPGVPLLPD TSTFYGSLIAELPSSPPAQPSPQAPAARRLPPPLVRTSSPWPSSDSLCSRRGLASPRLSLAPAE AWKAKKKQELHQANSSPLLRGSHPLELWAWELGHRSSKNLSQSPGPGSCFPAAVPGALVAWRAL GPQLLRNSNELATRPLPPVPLSPGGTHTQSPQTQHSVEPQASAPLPVLSPSRSPSPQPSSLSGP SPASSRLSSSSLSSLGEDQDSVLTPEEVALCLELSEGEETPRNSISPMPRAPSPPTTYGYISIP TASELADVGRAGGGVASEGGGLLCPPRPCPTPTPSEGSLANGWGSASEDNAPSARASLVSSSDG SFLADAHFARALGMAVDSFGFGLEPREADCVFTDVSSPPSPRDDIFLTPTLSLPLWEWRPDWLE DIEVNYTQQLGRGLPPWTPDSGISSQ hide sequence

RefSeq Acc Id:

ENSCLAP00000024617 ⟸ ENSCLAT00000024855

RefSeq Acc Id:

ENSCLAP00000024615 ⟸ ENSCLAT00000024853

RefSeq Acc Id:

ENSCLAP00000024616 ⟸ ENSCLAT00000024854

Protein Domains

Fibronectin type-III Ig-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCLAG00000016907	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCLAT00000024853.1	UniProtKB/TrEMBL
	ENSCLAT00000024854	ENTREZGENE
	ENSCLAT00000024854.1	UniProtKB/TrEMBL
	ENSCLAT00000024855	ENTREZGENE
	ENSCLAT00000024855.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	FN3_dom	UniProtKB/TrEMBL
	FN3_sf	UniProtKB/TrEMBL
	Ig-like_dom	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	Ig_I-set	UniProtKB/TrEMBL
	Ig_sub	UniProtKB/TrEMBL
	Ig_sub2	UniProtKB/TrEMBL
NCBI Gene	Robo4	ENTREZGENE
PANTHER	PROTEIN SIDEKICK	UniProtKB/TrEMBL
	PROTEIN SIDEKICK	UniProtKB/TrEMBL
Pfam	fn3	UniProtKB/TrEMBL
	I-set	UniProtKB/TrEMBL
	Ig_3	UniProtKB/TrEMBL
PROSITE	FN3	UniProtKB/TrEMBL
	IG_LIKE	UniProtKB/TrEMBL
SMART	FN3	UniProtKB/TrEMBL
	IGc2	UniProtKB/TrEMBL
	SM00409	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
	SSF49265	UniProtKB/TrEMBL
UniProt	A0A8C2W3F7_CHILA	UniProtKB/TrEMBL
	A0A8C2W3F9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C2W847_CHILA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-08-25	Robo4	roundabout guidance receptor 4		roundabout, axon guidance receptor, homolog 4 (Drosophila)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM