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Gene: MIB2 (MIB E3 ubiquitin protein ligase 2) Pan paniscus

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Symbol:

MIB2

Name:

MIB E3 ubiquitin protein ligase 2

RGD ID:

11853548

Description:

ENCODES a protein that exhibits metal ion binding (inferred); transferase activity (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN positive regulation of canonical NF-kappaB signal transduction (ortholog); regulation of postsynaptic neurotransmitter receptor internalization (ortholog); regulation protein catabolic process at postsynapse (ortholog); ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); congenital myasthenic syndrome 8 (ortholog); COVID-19 (ortholog); FOUND IN glutamatergic synapse (ortholog); postsynapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

E3 ubiquitin-protein ligase MIB2; mindbomb E3 ubiquitin protein ligase 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	226,586,500 - 226,604,001 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	225,242,442 - 225,261,089 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	379,326 - 395,041 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	1,539,640 - 1,552,913 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	1,539,634 - 1,557,517 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
MIB2	Bonobo	COVID-19		ISO	MIB2 (Homo sapiens)	9068941	mRNA:decreased expression:peripheral blood mononuclear cell (human)	RGD	PMID:32228226 and REF_RGD_ID:28912744

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
MIB2	Bonobo	chromosome 1p36 deletion syndrome		ISO	MIB2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Chromosome 1p36 deletion syndrome	ClinVar	PMID:25741868
MIB2	Bonobo	congenital myasthenic syndrome 8		ISO	MIB2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Congenital myasthenic syndrome 8	ClinVar	PMID:24951643 and PMID:28492532
MIB2	Bonobo	dilated cardiomyopathy 1LL		ISO	MIB2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Left ventricular noncompaction 8	ClinVar	PMID:28492532
MIB2	Bonobo	Ehlers-Danlos syndrome spondylodysplastic type 2		ISO	MIB2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Ehlers-Danlos syndrome more ...	ClinVar	PMID:10862081 more ...
MIB2	Bonobo	Goldberg-Shprintzen syndrome		ISO	MIB2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Shprintzen-Goldberg syndrome	ClinVar	PMID:23892090 more ...
MIB2	Bonobo	Idiopathic Generalized Epilepsy		ISO	MIB2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Idiopathic generalized epilepsy	ClinVar	PMID:28492532
MIB2	Bonobo	immunodeficiency 16		ISO	MIB2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Combined immunodeficiency due to OX40 deficiency	ClinVar	PMID:10862081 more ...
MIB2	Bonobo	immunodeficiency 38		ISO	MIB2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Mendelian susceptibility to mycobacterial diseases due to complete ISG15 deficiency	ClinVar	PMID:10862081 more ...
MIB2	Bonobo	Joubert syndrome 25		ISO	MIB2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Joubert syndrome 25	ClinVar	PMID:10862081 more ...
MIB2	Bonobo	Neurodevelopmental Disorders		ISO	MIB2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Neurodevelopmental disorder	ClinVar	PMID:25741868
MIB2	Bonobo	Peroxisome Biogenesis Disorder, Complementation Group 7		ISO	MIB2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Peroxisome biogenesis disorder and complementation group 7	ClinVar	PMID:10862081 more ...
MIB2	Bonobo	Shprintzen-Goldberg Craniosynostosis		ISO	MIB2 (Homo sapiens)	8554872	ClinVar Annotator: match by term: Shprintzen-Goldberg syndrome	ClinVar	PMID:23892090 more ...

Biological Process

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
MIB2	Bonobo	Notch signaling pathway	involved_in	IEA	UniProtKB-KW:KW-0914	150520179		UniProt	GO_REF:0000043
MIB2	Bonobo	positive regulation of canonical NF-kappaB signal transduction	involved_in	ISO	MIB2 (Homo sapiens)	9068941	PMID:12761501	UniProt	PMID:12761501
MIB2	Bonobo	protein ubiquitination	involved_in	IEA	InterPro:IPR010606	150520179		InterPro	GO_REF:0000002
MIB2	Bonobo	protein ubiquitination	acts_upstream_of_or_within	IEA	UniProtKB:Q8R516 and ensembl:ENSMUSP00000099465	150520179		Ensembl	GO_REF:0000107
MIB2	Bonobo	protein ubiquitination	involved_in	IEA	PANTHER:PTN000653852 more ...	150520179		TreeGrafter	GO_REF:0000118
MIB2	Bonobo	protein ubiquitination	involved_in	IEA	UniPathway:UPA00143	150520179		UniProt	GO_REF:0000041
MIB2	Bonobo	regulation of postsynaptic neurotransmitter receptor internalization	involved_in	ISO	Mib2 (Rattus norvegicus)	9068941	PMID:17962190	SynGO	PMID:17962190 and REF_RGD_ID:405650227
MIB2	Bonobo	regulation protein catabolic process at postsynapse	involved_in	ISO	Mib2 (Rattus norvegicus)	9068941	PMID:17962190	SynGO	PMID:17962190 and REF_RGD_ID:405650227

Cellular Component

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
MIB2	Bonobo	cytoplasm	located_in	IEA	UniProtKB-KW:KW-0963	150520179		UniProt	GO_REF:0000043
MIB2	Bonobo	cytoplasm	located_in	IEA	UniProtKB-SubCell:SL-0086	150520179		UniProt	GO_REF:0000044
MIB2	Bonobo	cytoplasm	located_in	IEA	PANTHER:PTN000653852 more ...	150520179		TreeGrafter	GO_REF:0000118
MIB2	Bonobo	early endosome	located_in	IEA	UniProtKB:Q8R516 and ensembl:ENSMUSP00000099465	150520179		Ensembl	GO_REF:0000107
MIB2	Bonobo	glutamatergic synapse	is_active_in	ISO	Mib2 (Rattus norvegicus)	9068941	PMID:17962190	SynGO	PMID:17962190 and REF_RGD_ID:405650227
MIB2	Bonobo	plasma membrane	located_in	IEA	UniProtKB:Q8R516 and ensembl:ENSMUSP00000099465	150520179		Ensembl	GO_REF:0000107
MIB2	Bonobo	postsynapse	is_active_in	ISO	Mib2 (Rattus norvegicus)	9068941	PMID:17962190	SynGO	PMID:17962190 and REF_RGD_ID:405650227
MIB2	Bonobo	ubiquitin ligase complex	part_of	IEA	UniProtKB:Q8R516 and ensembl:ENSMUSP00000099465	150520179		Ensembl	GO_REF:0000107

Molecular Function

Only show annotations with direct experimental evidence (0 objects hidden)

Object Symbol	Species	Term	Qualifier	Evidence	With	Reference	Notes	Source	Original Reference(s)
MIB2	Bonobo	metal ion binding	enables	IEA	InterPro:IPR010606 and InterPro:IPR037252	150520179		InterPro	GO_REF:0000002
MIB2	Bonobo	metal ion binding	enables	IEA	UniProtKB-KW:KW-0479	150520179		UniProt	GO_REF:0000043
MIB2	Bonobo	protein binding	enables	ISO	UniProtKB:Q9UHD2	9068941	PMID:21903422	IntAct	PMID:21903422
MIB2	Bonobo	protein binding	enables	ISO	PR:A2AFI6 and PR:O35516	9068941	PMID:34635817	MGI	PMID:34635817
MIB2	Bonobo	transferase activity	enables	IEA	UniProtKB-KW:KW-0808	150520179		UniProt	GO_REF:0000043
MIB2	Bonobo	ubiquitin protein ligase activity	enables	IEA	UniProtKB:Q8R516 and ensembl:ENSMUSP00000099465	150520179		Ensembl	GO_REF:0000107
MIB2	Bonobo	ubiquitin-protein transferase activity	enables	IEA	InterPro:IPR010606 and InterPro:IPR037252	150520179		InterPro	GO_REF:0000002
MIB2	Bonobo	ubiquitin-protein transferase activity	enables	IEA	UniProtKB:Q8R516 and ensembl:ENSMUSP00000099465	150520179		Ensembl	GO_REF:0000107
MIB2	Bonobo	zinc ion binding	enables	IEA	InterPro:IPR000433	150520179		InterPro	GO_REF:0000002
MIB2	Bonobo	zinc ion binding	enables	IEA	UniProtKB-KW:KW-0863	150520179		UniProt	GO_REF:0000043

PMID:22301074	PMID:30032202

MIB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	226,586,500 - 226,604,001 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	225,242,442 - 225,261,089 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	379,326 - 395,041 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	1,539,640 - 1,552,913 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	1,539,634 - 1,557,517 (+)	Ensembl	panpan1.1		panPan2

MIB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	1,613,731 - 1,630,605 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	1,615,454 - 1,630,605 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	1,550,880 - 1,565,985 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	1,540,747 - 1,555,848 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	1	1,016,532 - 1,030,942 (-)	NCBI		Celera
Cytogenetic Map	1	p36.33	NCBI
HuRef	1	824,580 - 841,846 (+)	NCBI		HuRef
CHM1_1	1	1,537,413 - 1,553,030 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	1,048,236 - 1,065,110 (+)	NCBI		T2T-CHM13v2.0

Mib2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	155,738,925 - 155,753,711 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	155,739,134 - 155,753,655 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	155,654,468 - 155,669,254 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	155,654,677 - 155,669,198 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	155,028,579 - 155,043,336 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	154,498,482 - 154,512,614 (-)	NCBI		MGSCv36	mm8
Celera	4	157,929,347 - 157,944,090 (-)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	86.86	NCBI

Mib2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	171,526,037 - 171,542,479 (-)	NCBI		GRCr8
mRatBN7.2	5	166,243,776 - 166,259,944 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	166,243,776 - 166,259,650 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	168,948,781 - 168,964,652 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	170,770,200 - 170,786,071 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	170,732,739 - 170,748,610 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	173,082,943 - 173,099,353 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	173,082,943 - 173,098,816 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	176,558,657 - 176,574,530 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	172,490,963 - 172,497,379 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	172,507,501 - 172,515,596 (-)	NCBI
Celera	5	164,444,700 - 164,460,443 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

Mib2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955486	9,271,099 - 9,285,682 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955486	9,273,580 - 9,285,682 (-)	NCBI	ChiLan1.0	ChiLan1.0

MIB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	56,680,526 - 56,693,551 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	56,581,550 - 56,693,544 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	56,756,140 - 56,769,077 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	56,882,471 - 56,895,406 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	56,882,507 - 56,895,503 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	56,873,293 - 56,886,228 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	56,765,635 - 56,778,536 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	57,155,552 - 57,168,487 (+)	NCBI		UU_Cfam_GSD_1.0

Mib2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	27,819,341 - 27,832,454 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936737	1,633,495 - 1,646,598 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MIB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	63,787,201 - 63,800,423 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	63,787,200 - 63,800,425 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	58,216,225 - 58,229,985 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MIB2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	129,878,014 - 129,893,239 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	129,877,142 - 129,884,894 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666054	34,333,028 - 34,349,732 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mib2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624818	8,077,851 - 8,099,547 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624818	8,078,677 - 8,091,448 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.


RefSeq Transcripts	XM_034953198	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953200	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953210	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953219	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953228	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953230	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953242	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953264	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953271	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034953277	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055099338	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055099344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055099347	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595056	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595057	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595068	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595069	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595070	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595072	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595073	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595074	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595075	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595078	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595081	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063595082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000058204 ⟹ ENSPPAP00000035316

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	1,539,634 - 1,552,913 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000058211 ⟹ ENSPPAP00000035323

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	1,545,676 - 1,557,517 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000058214 ⟹ ENSPPAP00000035326

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	1,546,574 - 1,552,686 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000058219 ⟹ ENSPPAP00000035331

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	1,546,574 - 1,552,685 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000058225 ⟹ ENSPPAP00000035337

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	1,546,574 - 1,550,202 (+)	Ensembl

RefSeq Acc Id:

XM_034953198 ⟹ XP_034809089

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,604,000 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,261,073 (-)	NCBI
Mhudiblu_PPA_v0	1	379,327 - 395,041 (+)	NCBI

RefSeq Acc Id:

XM_034953200 ⟹ XP_034809091

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,604,001 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,261,089 (-)	NCBI
Mhudiblu_PPA_v0	1	379,326 - 395,041 (+)	NCBI

RefSeq Acc Id:

XM_034953210 ⟹ XP_034809101

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,999 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,261,064 (-)	NCBI
Mhudiblu_PPA_v0	1	379,328 - 395,041 (+)	NCBI

RefSeq Acc Id:

XM_034953211 ⟹ XP_034809102

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,997 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,259,641 (-)	NCBI
Mhudiblu_PPA_v0	1	379,329 - 395,041 (+)	NCBI

RefSeq Acc Id:

XM_034953219 ⟹ XP_034809110

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,604,000 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,261,070 (-)	NCBI
Mhudiblu_PPA_v0	1	379,327 - 395,041 (+)	NCBI

RefSeq Acc Id:

XM_034953228 ⟹ XP_034809119

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,996 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,259,624 (-)	NCBI
Mhudiblu_PPA_v0	1	379,330 - 395,041 (+)	NCBI

RefSeq Acc Id:

XM_034953230 ⟹ XP_034809121

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,994 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,259,619 (-)	NCBI
Mhudiblu_PPA_v0	1	379,330 - 395,041 (+)	NCBI

RefSeq Acc Id:

XM_034953231 ⟹ XP_034809122

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,999 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,261,067 (-)	NCBI
Mhudiblu_PPA_v0	1	379,327 - 395,041 (+)	NCBI

RefSeq Acc Id:

XM_034953235 ⟹ XP_034809126

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,997 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,259,629 (-)	NCBI
Mhudiblu_PPA_v0	1	379,329 - 395,041 (+)	NCBI

RefSeq Acc Id:

XM_034953264 ⟹ XP_034809155

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,601,711 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,259,605 (-)	NCBI
Mhudiblu_PPA_v0	1	379,330 - 395,041 (+)	NCBI

RefSeq Acc Id:

XM_034953269 ⟹ XP_034809160

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,601,720 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,259,531 (-)	NCBI
Mhudiblu_PPA_v0	1	379,335 - 395,041 (+)	NCBI

RefSeq Acc Id:

XM_034953271 ⟹ XP_034809162

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,601,697 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,259,573 (-)	NCBI
Mhudiblu_PPA_v0	1	379,333 - 395,041 (+)	NCBI

RefSeq Acc Id:

XM_055099338 ⟹ XP_054955313

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,993 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,259,612 (-)	NCBI

RefSeq Acc Id:

XM_055099344 ⟹ XP_054955319

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,601,711 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,259,580 (-)	NCBI

RefSeq Acc Id:

XM_055099347 ⟹ XP_054955322

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,601,711 (-)	NCBI
NHGRI_mPanPan1	1	225,242,442 - 225,259,559 (-)	NCBI

RefSeq Acc Id:

XM_063595056 ⟹ XP_063451126

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,998 (-)	NCBI

RefSeq Acc Id:

XM_063595057 ⟹ XP_063451127

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,998 (-)	NCBI

RefSeq Acc Id:

XM_063595065 ⟹ XP_063451135

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,997 (-)	NCBI

RefSeq Acc Id:

XM_063595067 ⟹ XP_063451137

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,997 (-)	NCBI

RefSeq Acc Id:

XM_063595068 ⟹ XP_063451138

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,995 (-)	NCBI

RefSeq Acc Id:

XM_063595069 ⟹ XP_063451139

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,997 (-)	NCBI

RefSeq Acc Id:

XM_063595070 ⟹ XP_063451140

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,997 (-)	NCBI

RefSeq Acc Id:

XM_063595072 ⟹ XP_063451142

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,995 (-)	NCBI

RefSeq Acc Id:

XM_063595073 ⟹ XP_063451143

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,998 (-)	NCBI

RefSeq Acc Id:

XM_063595074 ⟹ XP_063451144

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,996 (-)	NCBI

RefSeq Acc Id:

XM_063595075 ⟹ XP_063451145

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,993 (-)	NCBI

RefSeq Acc Id:

XM_063595076 ⟹ XP_063451146

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,601,711 (-)	NCBI

RefSeq Acc Id:

XM_063595077 ⟹ XP_063451147

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,601,697 (-)	NCBI

RefSeq Acc Id:

XM_063595078 ⟹ XP_063451148

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,994 (-)	NCBI

RefSeq Acc Id:

XM_063595079 ⟹ XP_063451149

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,603,994 (-)	NCBI

RefSeq Acc Id:

XM_063595080 ⟹ XP_063451150

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,601,697 (-)	NCBI

RefSeq Acc Id:

XM_063595081 ⟹ XP_063451151

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,593,797 (-)	NCBI

RefSeq Acc Id:

XM_063595082 ⟹ XP_063451152

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	226,586,500 - 226,593,792 (-)	NCBI


Protein RefSeqs	XP_034809089	(Get FASTA)	NCBI Sequence Viewer
	XP_034809091	(Get FASTA)	NCBI Sequence Viewer
	XP_034809101	(Get FASTA)	NCBI Sequence Viewer
	XP_034809102	(Get FASTA)	NCBI Sequence Viewer
	XP_034809110	(Get FASTA)	NCBI Sequence Viewer
	XP_034809119	(Get FASTA)	NCBI Sequence Viewer
	XP_034809121	(Get FASTA)	NCBI Sequence Viewer
	XP_034809122	(Get FASTA)	NCBI Sequence Viewer
	XP_034809126	(Get FASTA)	NCBI Sequence Viewer
	XP_034809155	(Get FASTA)	NCBI Sequence Viewer
	XP_034809160	(Get FASTA)	NCBI Sequence Viewer
	XP_034809162	(Get FASTA)	NCBI Sequence Viewer
	XP_054955313	(Get FASTA)	NCBI Sequence Viewer
	XP_054955319	(Get FASTA)	NCBI Sequence Viewer
	XP_054955322	(Get FASTA)	NCBI Sequence Viewer
	XP_063451126	(Get FASTA)	NCBI Sequence Viewer
	XP_063451127	(Get FASTA)	NCBI Sequence Viewer
	XP_063451135	(Get FASTA)	NCBI Sequence Viewer
	XP_063451137	(Get FASTA)	NCBI Sequence Viewer
	XP_063451138	(Get FASTA)	NCBI Sequence Viewer
	XP_063451139	(Get FASTA)	NCBI Sequence Viewer
	XP_063451140	(Get FASTA)	NCBI Sequence Viewer
	XP_063451142	(Get FASTA)	NCBI Sequence Viewer
	XP_063451143	(Get FASTA)	NCBI Sequence Viewer
	XP_063451144	(Get FASTA)	NCBI Sequence Viewer
	XP_063451145	(Get FASTA)	NCBI Sequence Viewer
	XP_063451146	(Get FASTA)	NCBI Sequence Viewer
	XP_063451147	(Get FASTA)	NCBI Sequence Viewer
	XP_063451148	(Get FASTA)	NCBI Sequence Viewer
	XP_063451149	(Get FASTA)	NCBI Sequence Viewer
	XP_063451150	(Get FASTA)	NCBI Sequence Viewer
	XP_063451151	(Get FASTA)	NCBI Sequence Viewer
	XP_063451152	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000035316.1
	ENSPPAP00000035323.1
	ENSPPAP00000035326.1
	ENSPPAP00000035331.1
	ENSPPAP00000035337.1

RefSeq Acc Id:	XP_034809091 ⟸ XM_034953200
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_034809089 ⟸ XM_034953198
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_034809110 ⟸ XM_034953219
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_034809122 ⟸ XM_034953231
- Peptide Label:	isoform X13

RefSeq Acc Id:	XP_034809101 ⟸ XM_034953210
- Peptide Label:	isoform X5

Protein Domains

MIB/HERC2 RING-type ZZ-type

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000040418	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000058204.1	UniProtKB/TrEMBL
	ENSPPAT00000058211.1	UniProtKB/TrEMBL
	ENSPPAT00000058214.1	UniProtKB/TrEMBL
	ENSPPAT00000058219.1	UniProtKB/TrEMBL
	ENSPPAT00000058225.1	UniProtKB/TrEMBL
Gene3D-CATH	1.25.40.20	UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/TrEMBL
	3.30.60.90	UniProtKB/TrEMBL
	SH3 Domains	UniProtKB/TrEMBL
InterPro	Ankyrin_rpt	UniProtKB/TrEMBL
	Ankyrin_rpt-contain_sf	UniProtKB/TrEMBL
	MIB1/2_ZZ	UniProtKB/TrEMBL
	Mib_Herc2	UniProtKB/TrEMBL
	Mib_Herc2_sf	UniProtKB/TrEMBL
	SH3_15	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_ZZ	UniProtKB/TrEMBL
	Znf_ZZ_sf	UniProtKB/TrEMBL
NCBI Gene	MIB2	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE MIB2	UniProtKB/TrEMBL
	E3 UBIQUITIN-PROTEIN LIGASE MIB2-RELATED	UniProtKB/TrEMBL
Pfam	Ank	UniProtKB/TrEMBL
	Ank_2	UniProtKB/TrEMBL
	MIB_HERC2	UniProtKB/TrEMBL
	PF00569	UniProtKB/TrEMBL
	SH3_15	UniProtKB/TrEMBL
	zf-C3HC4_3	UniProtKB/TrEMBL
PRINTS	ANKYRIN	UniProtKB/TrEMBL
PROSITE	ANK_REP_REGION	UniProtKB/TrEMBL
	ANK_REPEAT	UniProtKB/TrEMBL
	MIB_HERC2	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
	ZF_ZZ_1	UniProtKB/TrEMBL
	ZF_ZZ_2	UniProtKB/TrEMBL
SMART	ANK	UniProtKB/TrEMBL
	ZnF_ZZ	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
	SSF159034	UniProtKB/TrEMBL
	SSF48403	UniProtKB/TrEMBL
UniProt	A0A2R9C063	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9C0A1_PANPA	UniProtKB/TrEMBL
	A0A2R9C0S0	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9C0S9	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9C0T5_PANPA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-11-03	MIB2	MIB E3 ubiquitin protein ligase 2	MIB2	mindbomb E3 ubiquitin protein ligase 2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailable


InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailable


Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable

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Imported Disease Annotations - ClinVar