FLI1 (Fli-1 proto-oncogene, ETS transcription factor) - Rat Genome Database

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Gene: FLI1 (Fli-1 proto-oncogene, ETS transcription factor) Pan paniscus
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Symbol: FLI1
Name: Fli-1 proto-oncogene, ETS transcription factor
RGD ID: 11793369
Description: ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); INVOLVED IN animal organ morphogenesis (ortholog); blood circulation (ortholog); megakaryocyte development (ortholog); ASSOCIATED WITH chromosome 11 partial duplication syndrome (ortholog); Dwarfism (ortholog); Ewing sarcoma (ortholog); FOUND IN cytosol (inferred); nuclear body (inferred); nucleoplasm (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Friend leukemia integration 1 transcription factor; Friend leukemia virus integration 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29129,376,354 - 129,494,803 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111130,484,068 - 130,602,419 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011123,506,859 - 123,626,024 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111127,409,301 - 127,527,521 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11127,409,301 - 127,530,312 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytosol  (IEA)
nuclear body  (IEA)
nucleoplasm  (IEA)
nucleus  (IEA)

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FLI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29129,376,354 - 129,494,803 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111130,484,068 - 130,602,419 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011123,506,859 - 123,626,024 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111127,409,301 - 127,527,521 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11127,409,301 - 127,530,312 (+)Ensemblpanpan1.1panPan2
FLI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811128,685,351 - 128,813,267 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11128,686,535 - 128,813,267 (+)EnsemblGRCh38hg38GRCh38
GRCh3711128,556,430 - 128,683,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611128,069,199 - 128,187,521 (+)NCBINCBI36Build 36hg18NCBI36
Build 3411128,069,198 - 128,187,520NCBI
Celera11125,728,561 - 125,849,286 (+)NCBICelera
Cytogenetic Map11q24.3NCBI
HuRef11124,504,750 - 124,631,960 (+)NCBIHuRef
CHM1_111128,442,436 - 128,569,169 (+)NCBICHM1_1
T2T-CHM13v2.011128,719,763 - 128,845,984 (+)NCBIT2T-CHM13v2.0
Fli1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39932,333,500 - 32,454,292 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl932,333,500 - 32,454,157 (-)EnsemblGRCm39 Ensembl
GRCm38932,422,204 - 32,543,432 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl932,422,204 - 32,542,861 (-)EnsemblGRCm38mm10GRCm38
MGSCv37932,229,793 - 32,348,953 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36932,171,773 - 32,290,933 (-)NCBIMGSCv36mm8
Celera929,685,381 - 29,804,572 (-)NCBICelera
Cytogenetic Map9A4NCBI
cM Map917.74NCBI
Fli1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8839,089,526 - 39,209,511 (-)NCBIGRCr8
mRatBN7.2830,831,422 - 30,950,468 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl830,832,753 - 30,950,433 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx834,903,577 - 35,021,956 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0833,197,989 - 33,316,402 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0831,060,872 - 31,179,270 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0833,541,932 - 33,661,111 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl833,543,258 - 33,661,049 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0833,586,162 - 33,704,455 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4832,187,952 - 32,309,782 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1832,196,722 - 32,318,548 (-)NCBI
Celera832,284,160 - 32,401,673 (-)NCBICelera
Cytogenetic Map8q21NCBI
Fli1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541229,654,459 - 29,775,903 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541229,653,621 - 29,773,412 (+)NCBIChiLan1.0ChiLan1.0
FLI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.155,841,533 - 5,968,329 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl55,843,023 - 5,966,822 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha55,899,065 - 6,025,150 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.055,799,196 - 5,922,120 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl55,799,200 - 5,920,609 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.155,858,425 - 5,981,002 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.055,836,777 - 5,962,717 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.055,870,453 - 5,993,208 (-)NCBIUU_Cfam_GSD_1.0
Fli1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947110,872,609 - 111,001,492 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365723,448,862 - 3,577,836 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365723,448,870 - 3,576,406 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FLI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl955,612,901 - 55,749,778 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1955,612,905 - 55,749,784 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2961,707,515 - 61,810,415 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FLI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11119,817,987 - 119,945,378 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1119,827,222 - 119,946,662 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660436,144,187 - 6,261,677 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fli1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248123,004,628 - 3,139,101 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248123,004,631 - 3,138,901 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003819883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSPPAT00000057498   ⟹   ENSPPAP00000034615
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11127,409,301 - 127,530,312 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000057503   ⟹   ENSPPAP00000034620
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11127,409,574 - 127,530,312 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000057516   ⟹   ENSPPAP00000034634
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11127,473,493 - 127,526,098 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000057521   ⟹   ENSPPAP00000034638
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11127,479,954 - 127,526,098 (+)Ensembl
RefSeq Acc Id: XM_003819883   ⟹   XP_003819931
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v29129,376,354 - 129,494,803 (+)NCBI
NHGRI_mPanPan111130,484,068 - 130,602,419 (+)NCBI
Mhudiblu_PPA_v011123,506,859 - 123,626,024 (+)NCBI
PanPan1.111127,409,301 - 127,527,521 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003819931 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000034615
  ENSPPAP00000034615.1
  ENSPPAP00000034620.1
  ENSPPAP00000034634.1
  ENSPPAP00000034638.1
RefSeq Acc Id: XP_003819931   ⟸   XM_003819883
- UniProtKB: A0A2R9C1G7 (UniProtKB/TrEMBL),   A0A2R9BY86 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000034615   ⟸   ENSPPAT00000057498
Ensembl Acc Id: ENSPPAP00000034620   ⟸   ENSPPAT00000057503
Ensembl Acc Id: ENSPPAP00000034634   ⟸   ENSPPAT00000057516
Ensembl Acc Id: ENSPPAP00000034638   ⟸   ENSPPAT00000057521
Protein Domains
ETS   PNT


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040122 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057498.1 UniProtKB/TrEMBL
  ENSPPAT00000057503.1 UniProtKB/TrEMBL
  ENSPPAT00000057516.1 UniProtKB/TrEMBL
  ENSPPAT00000057521.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/TrEMBL
  1.10.150.50 UniProtKB/TrEMBL
InterPro Ets_dom UniProtKB/TrEMBL
  ETS_fam UniProtKB/TrEMBL
  Pointed_dom UniProtKB/TrEMBL
  SAM/pointed_sf UniProtKB/TrEMBL
  SAM_PNT-FLI-1 UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/TrEMBL
KEGG Report pps:100971241 UniProtKB/TrEMBL
NCBI Gene FLI1 ENTREZGENE
PANTHER PTHR11849 UniProtKB/TrEMBL
  PTHR11849:SF161 UniProtKB/TrEMBL
Pfam Ets UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
PRINTS ETSDOMAIN UniProtKB/TrEMBL
PROSITE ETS_DOMAIN_1 UniProtKB/TrEMBL
  ETS_DOMAIN_2 UniProtKB/TrEMBL
  ETS_DOMAIN_3 UniProtKB/TrEMBL
  PNT UniProtKB/TrEMBL
SMART ETS UniProtKB/TrEMBL
  SAM_PNT UniProtKB/TrEMBL
Superfamily-SCOP SSF46785 UniProtKB/TrEMBL
  SSF47769 UniProtKB/TrEMBL
UniProt A0A2R9BY86 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C1G7 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C1H0_PANPA UniProtKB/TrEMBL
  A0A2R9C860_PANPA UniProtKB/TrEMBL