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Gene: MAP4K3 (mitogen-activated protein kinase kinase kinase kinase 3) Pan paniscus

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Symbol:

MAP4K3

Name:

mitogen-activated protein kinase kinase kinase kinase 3

RGD ID:

11776248

Description:

ENCODES a protein that exhibits SH3 domain binding (ortholog); INVOLVED IN protein phosphorylation (ortholog); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; ASSOCIATED WITH high grade glioma (ortholog); Lynch syndrome (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (inferred)

Type:

protein-coding

RefSeq Status:

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	87,032,042 - 87,220,052 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	87,036,010 - 87,224,027 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	39,286,787 - 39,474,780 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	40,040,492 - 40,228,109 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	40,040,497 - 40,228,109 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

high grade glioma (ISO)

Lynch syndrome (ISO)

Neurodevelopmental Disorders (ISO)

Noonan syndrome 4 (ISO)

Temporomandibular Joint Disorders (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chromatin remodeling (IEA)

intracellular signal transduction (IEA)

MAPK cascade (IEA)

protein phosphorylation (ISO)

response to tumor necrosis factor (IEA)

response to UV (IEA)

Cellular Component

cytoplasm (IEA)

Molecular Function

3-phosphoinositide-dependent protein kinase activity (IEA)

AMP-activated protein kinase activity (IEA)

ATP binding (IEA)

DNA-dependent protein kinase activity (IEA)

eukaryotic translation initiation factor 2alpha kinase activity (IEA)

histone H2AS1 kinase activity (IEA)

histone H2AS121 kinase activity (IEA)

histone H2AT120 kinase activity (IEA)

histone H2AXS139 kinase activity (IEA)

histone H2BS14 kinase activity (IEA)

histone H2BS36 kinase activity (IEA)

histone H3S10 kinase activity (IEA)

histone H3S28 kinase activity (IEA)

histone H3S57 kinase activity (IEA)

histone H3T11 kinase activity (IEA)

histone H3T3 kinase activity (IEA)

histone H3T45 kinase activity (IEA)

histone H3T6 kinase activity (IEA)

histone H4S1 kinase activity (IEA)

MAP kinase kinase kinase kinase activity (IEA)

protein binding (ISO)

protein kinase activity (IEA)

protein serine kinase activity (IEA)

protein serine/threonine kinase activity (IEA)

Rho-dependent protein serine/threonine kinase activity (IEA)

ribosomal protein S6 kinase activity (IEA)

SH3 domain binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

tumor necrosis factor mediated signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

MAP4K3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	87,032,042 - 87,220,052 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	87,036,010 - 87,224,027 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	39,286,787 - 39,474,780 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	40,040,492 - 40,228,109 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	40,040,497 - 40,228,109 (-)	Ensembl	panpan1.1		panPan2

MAP4K3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	39,249,266 - 39,437,285 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	39,249,266 - 39,437,301 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	39,476,407 - 39,664,426 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	39,329,926 - 39,517,723 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	39,388,073 - 39,575,870	NCBI
Celera	2	39,317,367 - 39,505,201 (-)	NCBI		Celera
Cytogenetic Map	2	p22.1	NCBI
HuRef	2	39,215,530 - 39,403,591 (-)	NCBI		HuRef
CHM1_1	2	39,406,810 - 39,594,778 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	39,258,084 - 39,446,168 (-)	NCBI		T2T-CHM13v2.0

Map4k3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	17	80,887,942 - 81,039,118 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	17	80,887,941 - 81,035,914 (-)	Ensembl		GRCm39 Ensembl
GRCm38	17	80,580,513 - 80,728,806 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	17	80,580,512 - 80,728,485 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	17	80,979,852 - 81,127,433 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	17	80,488,838 - 80,636,419 (-)	NCBI		MGSCv36	mm8
MGSCv36	17	79,860,491 - 80,008,566 (-)	NCBI		MGSCv36	mm8
Celera	17	84,897,744 - 85,059,626 (-)	NCBI		Celera
Cytogenetic Map	17	E3	NCBI
cM Map	17	50.97	NCBI

Map4k3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	20,029,246 - 20,198,583 (+)	NCBI		GRCr8
mRatBN7.2	6	14,276,623 - 14,446,321 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	14,277,121 - 14,446,334 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	14,582,521 - 14,745,689 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	14,897,736 - 15,066,918 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	14,393,979 - 14,563,171 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	3,276,732 - 3,444,519 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	3,276,738 - 3,444,519 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	3,247,181 - 3,414,716 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	3,473,694 - 3,642,461 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	3,475,028 - 3,642,293 (-)	NCBI
Celera	6	13,956,412 - 14,123,546 (+)	NCBI		Celera
Cytogenetic Map	6	q12	NCBI

Map4k3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955441	6,846,719 - 6,956,418 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955441	6,843,066 - 6,956,443 (-)	NCBI	ChiLan1.0	ChiLan1.0

MAP4K3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	31,253,632 - 31,439,148 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	31,254,941 - 31,439,118 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	31,006,278 - 31,200,097 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	31,910,677 - 32,098,182 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	31,910,926 - 32,098,323 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	31,131,531 - 31,319,037 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	31,201,764 - 31,389,216 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	31,415,443 - 31,602,890 (-)	NCBI		UU_Cfam_GSD_1.0

Map4k3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	40,456,473 - 40,633,948 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936508	11,884,684 - 12,064,066 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936508	11,885,066 - 12,062,560 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAP4K3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	100,887,143 - 101,084,677 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	100,887,148 - 101,084,667 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

MAP4K3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	67,931,906 - 68,121,640 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	67,931,940 - 68,122,556 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	43,860,848 - 43,989,643 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Map4k3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	20,715,296 - 20,875,393 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624738	20,716,430 - 20,874,930 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003817628	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_003817629	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034952985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034952986	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034952987	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_004669789	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000036586 ⟹ ENSPPAP00000013911

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	2A	40,040,497 - 40,228,109 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000036591 ⟹ ENSPPAP00000013916

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	2A	40,040,497 - 40,228,109 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000036597 ⟹ ENSPPAP00000013922

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	2A	40,041,844 - 40,147,892 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000036602 ⟹ ENSPPAP00000013927

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	2A	40,117,108 - 40,227,972 (-)	Ensembl

RefSeq Acc Id:

XM_003817628 ⟹ XP_003817676

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	12	87,032,179 - 87,220,052 (+)	NCBI
NHGRI_mPanPan1	2A	87,036,010 - 87,224,027 (+)	NCBI
Mhudiblu_PPA_v0	2A	39,286,787 - 39,474,780 (-)	NCBI
PanPan1.1	2A	40,040,497 - 40,228,109 (-)	NCBI

Sequence:

show sequence

GCCGCAGCGTGGAGCCGGGTGATTGTGACCGCCGGGGGAGCCGGGAGCCGGCCGCGGCGCCCTC
TCTCCGTGTGGCCCCCTGAGCGGCCCCCCCTCCCCTGCCCGGGGAGGGAGGCGGGGGGCACCTG
GGGCCCGCCATGAACCCGGGCTTCGATTTGTCCCGCCGGAACCCGCAGGAGGACTTCGAGCTGA
TTCAGCGCATCGGCAGCGGCACCTACGGCGACGTCTACAAGGCACGGAATGTTAACACTGGTGA
ATTAGCAGCAATTAAAGTAATAAAATTGGAACCAGGAGAAGACTTTGCAGTTGTGCAGCAAGAA
ATTATTATGATGAAAGACTGTAAACACCCAAATATTGTTGCTTATTTTGGAAGCTATCTCAGGC
GAGATAAGCTTTGGATTTGCATGGAGTTTTGTGGAGGTGGTTCTTTACAGGATATTTATCACGT
AACTGGACCTCTGTCAGAACTGCAAATTGCATATGTTAGCAGAGAAACACTGCAGGGATTATAT
TATCTTCACAGTAAAGGAAAAATGCACAGAGATATAAAGGGAGCTAACATTCTATTAACGGATA
ATGGTCATGTGAAACTGGCTGATTTTGGAGTATCTGCACAGATAACAGCTACAATTGCCAAACG
GAAGTCTTTCATTGGCACACCATATTGGATGGCTCCAGAAGTTGCAGCTGTTGAGAGGAAGGGG
GGTTACAATCAACTCTGTGATCTCTGGGCAGTGGGAATCACTGCCATAGAACTTGCAGAGCTTC
AGCCTCCTATGTTTGACTTACACCCAATGAGAGCATTATTTCTAATGACAAAAAGCAATTTTCA
GCCTCCTAAACTAAAGGATAAAATGAAATGGTCAAATAGTTTTCATCACTTTGTGAAAATGGCA
CTTACCAAAAATCCGAAAAAAAGACCTACTGCTGAAAAATTATTACAGCATCCTTTTGTAACAC
AACATTTGACACGGTCTTTGGCAATCGAGCTGTTGGATAAAGTAAATAATCCAGATCATTCCAC
TTACCATGATTTCGATGATGATGATCCTGAGCCTCTTGTTGCTGTACCACATAGAATTCACTCA
ACAAGTAGAAACGTGAGAGAAGAAAAAACACGCTCAGAGATAAACTTTGGCCAAGTGAAATTTG
ATCCACCCTTAAGAAAGGAGACAGAACCACATCATGAACTTGATCTGCAACTGGAATATGGACA
AGGACACCAAGGTAGTTACTTTTTAGGTGCAAACAAGAGTCTTCTCAAGTCTGTTGAAGAAGAA
TTGCATCAGCGAGGACACGTCGCACATTTAGAAGATGATGAAGGAGATGATGATGAATCTAAAC
ACTCAACTCTGAAAGCAAAAGTTCCACCTCCTTTGCCACCAAAGCCTAAGTCTATCTTCATACC
ACAGGAAATGCATTCTACTGAGGATGAAAATCAAGGAACAATCAAGAGATGTCCCATGTCAGGG
AGCCCAGCAAAGCCATCCCAAGTTCCACCTAGACCACCACCTCCCAGATTACCCCCACACAAAC
CTGTTGCCTTAGGAAATGGAATGAGCTCCTTCCAGTTAAATGGTGAACGAGATGGCTCATTATG
TCAACAACAGAATGAACATAGAGGCACAAACCTTTCAAGAAAAGAAAAGAAAGATATACCAAAG
CCTATTAGTAATGGTCTTCCTCCAACACCTAAAGTGCATATGGGTGCATGTTTTTCAAAAGTTT
TTAATGGGTGTCCCTTGAAAATTCACTGTGCATCATCATGGATAAACCCAGATACAAGAGATCA
GTACTTGATATTTGGTGCCGAAGAAGGGATTTATACCCTCAATCTTAATGAACTTCATGAAACA
TCAATGGAACAGCTATTCCCTCGAAGGTGTACATGGTTGTATGTAATGAACAATTGCTTGCTAT
CAATATCTGGTAAAGCTTCTCAGCTTTATTCCCATAATTTACCAGGGCTTTTTGATTATGCAAG
ACAAATGCAAAAGTTACCTGTTGCTATTCCAGCACACAAACTCCCTGACAGAATACTGCCAAGG
AAATTTTCTGTATCAGCAAAAATCCCTGAAACCAAATGGTGCCAGAAGTGTTGTGTTGTAAGAA
ATCCTTACACGGGCCATAAATACCTATGTGGAGCACTTCAGACTAGCATTGTTCTATTAGAATG
GGTTGAACCAATGCAGAAATTTATGTTAATTAAGCACATAGATTTTCCTATACCATGTCCACTT
AGAATGTTTGAAATGCTGGTAGTTCCTGAACAGGAGTACCCTTTAGTTTGTGTTGGTGTCAGTA
GAGGTAGAGACTTCAACCAAGTGGTTCGATTTGAGACGGTCAATCCAAATTCTACCTCTTCGTG
GTTTACAGAATCAGATACCCCACAGACAAATGTTACTCATGTAACCCAACTGGAGAGAGATACC
ATCCTTGTATGCTTGGACTGTTGTATAAAAATAGTAAATCTCCAAGGAAGATTAAAATCTAGCA
GGAAATTATCATCAGAACTCACCTTTGATTTCCAGATTGAATCAATAGTGTGCCTACAAGACAG
TGTGCTAGCTTTCTGGAAACATGGAATGCAAGGTAGAAGTTTTAGATCTAATGAGGTAACACAA
GAAATTTCAGATAGCACAAGAATTTTCAGGCTGCTTGGATCTGACAGGGTCGTGGTTTTGGAAA
GTAGGCCAACTGATAACCCCACAGCAAATAGCAATTTGTACATCCTGGCGGGTCATGAAAACAG
TTACTGAGAATTGTTGTGCTTTGACAGTTAACTCTAGAAAGAAAGAACACTACCACTGCAACAT
TAATGGATGCTTGAAGCTGTACAAAAGCTGCAGTAACCTGTCTTCAGTTACTTTGTAATTTATT
GTGGCATGAGATAAGATGGGGAAAATTTTGTTTTAAGTGGTATGGATATATTTAGCATATTGAA
CCACACAAGTGCTTAATTCATTGTTATGTAATCTTTGTACATATAGGCAGTATTTTTTCTGTGA
AACTTCATATTGCTGAAGACATACACTAAGAATTTATGTAGATAATGTACTTTGATGAGATGTA
CAAGTAAGTGTCTTATCTGTACAGATGTAAATGTTGATGAAAATGCAATTGGGGTTAATATTTT
AAGAATTCTTTAGTATATTCTTGGGTGTGGCTATATTACAAAATGGGATGCTGGCAATGAAACA
ATACATTTAACACTATTGTATTTTTATTATATGTAATTTAGTAATATGAATATAAATCTTGTAA
CTTTTAAAATTGTAATGGAGGCTGTAATCATTTTATAATCTTTTTAATTTTAATGCAAGTACAC
TGGTGTTTATATTTGCACAAAGTATTGATATGTGATGTATTAAGTCACAAAAGTAAGCTGTGAC
ATTGTCTATAAGCATTTGGCTCCACAAATGTATTTGGATTGTTTTCTATGTGAAGCAAACCAAT
TATAATTAACCACATGTTGTAGTAACTGGTCTTTTTATATTTAAGCAGAATCCTGTAAGATTGC
TTGTCTTTGCTTAAAAACAATACCTTTGAACATTTTTGAATCACAGAATAGCGGTACCATGATA
GAATACTGCAATTGTGGTCTGAATTACAGTATGCACAAAGAATTAATTAGCATTATTAAAGAGT
CCTCACTAAACATTTCATATGATCACACTGAAGAACTGTAACATTCCATAGAGTGAAGTGGTTC
AAATTTCTCTTGGAATTTTTACTTTTGTTGGCCTTATTTTATGATCCTTTTCATATTTCTTTTG
ACTTAGAGTATTAATACATGGCCAAAATAATTTAGTTACTACCTCATACAAACAATATAATGGT
TACTACACATCACAGGAACTTAGTTTTGGTTTAAGTCATTTTTGATTGCTTTTTTCCAATGGAA
TATGTATATACCAGGTTTTAGCAAAATGCACACTTTTGGCTCTTTTTGGTATATGTTCTTTATA
TTTTAATGTGAGTATATACACTAAGAACAAACTAAATTGTGATTTATGATCTTCATTTATTGTA
ATGATAATGGTTTTAAAATATGTTCCTGATTGTACATATTGTAAAATAAACATGTTTTTTAACA
TGCTGTTGTA

hide sequence

RefSeq Acc Id:

XM_003817629 ⟹ XP_003817677

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	12	87,032,179 - 87,220,052 (+)	NCBI
NHGRI_mPanPan1	2A	87,036,010 - 87,224,027 (+)	NCBI
Mhudiblu_PPA_v0	2A	39,286,787 - 39,474,764 (-)	NCBI
PanPan1.1	2A	40,040,497 - 40,228,109 (-)	NCBI

Sequence:

show sequence

GCCGCAGCGTGGAGCCGGGTGATTGTGACCGCCGGGGGAGCCGGGAGCCGGCCGCGGCGCCCTC
TCTCCGTGTGGCCCCCTGAGCGGCCCCCCCTCCCCTGCCCGGGGAGGGAGGCGGGGGGCACCTG
GGGCCCGCCATGAACCCGGGCTTCGATTTGTCCCGCCGGAACCCGCAGGAGGACTTCGAGCTGA
TTCAGCGCATCGGCAGCGGCACCTACGGCGACGTCTACAAGGCACGGAATGTTAACACTGGTGA
ATTAGCAGCAATTAAAGTAATAAAATTGGAACCAGGAGAAGACTTTGCAGTTGTGCAGCAAGAA
ATTATTATGATGAAAGACTGTAAACACCCAAATATTGTTGCTTATTTTGGAAGCTATCTCAGGC
GAGATAAGCTTTGGATTTGCATGGAGTTTTGTGGAGGTGGTTCTTTACAGGATATTTATCACGT
AACTGGACCTCTGTCAGAACTGCAAATTGCATATGTTAGCAGAGAAACACTGCAGGGATTATAT
TATCTTCACAGTAAAGGAAAAATGCACAGAGATATAAAGGGAGCTAACATTCTATTAACGGATA
ATGGTCATGTGAAACTGGCTGATTTTGGAGTATCTGCACAGATAACAGCTACAATTGCCAAACG
GAAGTCTTTCATTGGCACACCATATTGGATGGCTCCAGAAGTTGCAGCTGTTGAGAGGAAGGGG
GGTTACAATCAACTCTGTGATCTCTGGGCAGTGGGAATCACTGCCATAGAACTTGCAGAGCTTC
AGCCTCCTATGTTTGACTTACACCCAATGAGAGCATTATTTCTAATGACAAAAAGCAATTTTCA
GCCTCCTAAACTAAAGGATAAAATGAAATGGTCAAATAGTTTTCATCACTTTGTGAAAATGGCA
CTTACCAAAAATCCGAAAAAAAGACCTACTGCTGAAAAATTATTACAGCATCCTTTTGTAACAC
AACATTTGACACGGTCTTTGGCAATCGAGCTGTTGGATAAAGTAAATAATCCAGATCATTCCAC
TTACCATGATTTCGATGATGATGATCCTGAGCCTCTTGTTGCTGTACCACATAGAATTCACTCA
ACAAGTAGAAACGTGAGAGAAGAAAAAACACGCTCAGAGATAAACTTTGGCCAAGTGAAATTTG
ATCCACCCTTAAGAAAGGAGACAGAACCACATCATGAACTTCCCGACAGTGATGGTTTTTTGGA
CAGTTCAGAAGAAATATACTACACTGCAAGATCTAATCTGGATCTGCAACTGGAATATGGACAA
GGACACCAAGGTAGTTACTTTTTAGGTGCAAACAAGAGTCTTCTCAAGTCTGTTGAAGAAGAAT
TGCATCAGCGAGGACACGTCGCACATTTAGAAGATGATGAAGGAGATGATGATGAATCTAAACA
CTCAACTCTGAAAGCAAAAGTTCCACCTCCTTTGCCACCAAAGCCTAAGTCTATCTTCATACCA
CAGGAAATGCATTCTACTGAGGATGAAAATCAAGGAACAATCAAGAGATGTCCCATGTCAGGGA
GCCCAGCAAAGCCATCCCAAGTTCCACCTAGACCACCACCTCCCAGATTACCCCCACACAAACC
TGTTGCCTTAGGAAATGGAATGAGCTCCTTCCAGTTAAATGGTGAACGAGATGGCTCATTATGT
CAACAACAGAATGAACATAGAGGCACAAACCTTTCAAGAAAAGAAAAGAAAGATATACCAAAGC
CTATTAGTAATGGTCTTCCTCCAACACCTAAAGTGCATATGGGTGCATGTTTTTCAAAAGTTTT
TAATGGGTGTCCCTTGAAAATTCACTGTGCATCATCATGGATAAACCCAGATACAAGAGATCAG
TACTTGATATTTGGTGCCGAAGAAGGGATTTATACCCTCAATCTTAATGAACTTCATGAAACAT
CAATGGAACAGCTATTCCCTCGAAGGTGTACATGGTTGTATGTAATGAACAATTGCTTGCTATC
AATATCTGGTAAAGCTTCTCAGCTTTATTCCCATAATTTACCAGGGCTTTTTGATTATGCAAGA
CAAATGCAAAAGTTACCTGTTGCTATTCCAGCACACAAACTCCCTGACAGAATACTGCCAAGGA
AATTTTCTGTATCAGCAAAAATCCCTGAAACCAAATGGTGCCAGAAGTGTTGTGTTGTAAGAAA
TCCTTACACGGGCCATAAATACCTATGTGGAGCACTTCAGACTAGCATTGTTCTATTAGAATGG
GTTGAACCAATGCAGAAATTTATGTTAATTAAGCACATAGATTTTCCTATACCATGTCCACTTA
GAATGTTTGAAATGCTGGTAGTTCCTGAACAGGAGTACCCTTTAGTTTGTGTTGGTGTCAGTAG
AGGTAGAGACTTCAACCAAGTGGTTCGATTTGAGACGGTCAATCCAAATTCTACCTCTTCGTGG
TTTACAGAATCAGATACCCCACAGACAAATGTTACTCATGTAACCCAACTGGAGAGAGATACCA
TCCTTGTATGCTTGGACTGTTGTATAAAAATAGTAAATCTCCAAGGAAGATTAAAATCTAGCAG
GAAATTATCATCAGAACTCACCTTTGATTTCCAGATTGAATCAATAGTGTGCCTACAAGACAGT
GTGCTAGCTTTCTGGAAACATGGAATGCAAGGTAGAAGTTTTAGATCTAATGAGGTAACACAAG
AAATTTCAGATAGCACAAGAATTTTCAGGCTGCTTGGATCTGACAGGGTCGTGGTTTTGGAAAG
TAGGCCAACTGATAACCCCACAGCAAATAGCAATTTGTACATCCTGGCGGGTCATGAAAACAGT
TACTGAGAATTGTTGTGCTTTGACAGTTAACTCTAGAAAGAAAGAACACTACCACTGCAACATT
AATGGATGCTTGAAGCTGTACAAAAGCTGCAGTAACCTGTCTTCAGTTACTTTGTAATTTATTG
TGGCATGAGATAAGATGGGGAAAATTTTGTTTTAAGTGGTATGGATATATTTAGCATATTGAAC
CACACAAGTGCTTAATTCATTGTTATGTAATCTTTGTACATATAGGCAGTATTTTTTCTGTGAA
ACTTCATATTGCTGAAGACATACACTAAGAATTTATGTAGATAATGTACTTTGATGAGATGTAC
AAGTAAGTGTCTTATCTGTACAGATGTAAATGTTGATGAAAATGCAATTGGGGTTAATATTTTA
AGAATTCTTTAGTATATTCTTGGGTGTGGCTATATTACAAAATGGGATGCTGGCAATGAAACAA
TACATTTAACACTATTGTATTTTTATTATATGTAATTTAGTAATATGAATATAAATCTTGTAAC
TTTTAAAATTGTAATGGAGGCTGTAATCATTTTATAATCTTTTTAATTTTAATGCAAGTACACT
GGTGTTTATATTTGCACAAAGTATTGATATGTGATGTATTAAGTCACAAAAGTAAGCTGTGACA
TTGTCTATAAGCATTTGGCTCCACAAATGTATTTGGATTGTTTTCTATGTGAAGCAAACCAATT
ATAATTAACCACATGTTGTAGTAACTGGTCTTTTTATATTTAAGCAGAATCCTGTAAGATTGCT
TGTCTTTGCTTAAAAACAATACCTTTGAACATTTTTGAATCACAGAATAGCGGTACCATGATAG
AATACTGCAATTGTGGTCTGAATTACAGTATGCACAAAGAATTAATTAGCATTATTAAAGAGTC
CTCACTAAACATTTCATATGATCACACTGAAGAACTGTAACATTCCATAGAGTGAAGTGGTTCA
AATTTCTCTTGGAATTTTTACTTTTGTTGGCCTTATTTTATGATCCTTTTCATATTTCTTTTGA
CTTAGAGTATTAATACATGGCCAAAATAATTTAGTTACTACCTCATACAAACAATATAATGGTT
ACTACACATCACAGGAACTTAGTTTTGGTTTAAGTCATTTTTGATTGCTTTTTTCCAATGGAAT
ATGTATATACCAGGTTTTAGCAAAATGCACACTTTTGGCTCTTTTTGGTATATGTTCTTTATAT
TTTAATGTGAGTATATACACTAAGAACAAACTAAATTGTGATTTATGATCTTCATTTATTGTAA
TGATAATGGTTTTAAAATATGTTCCTGATTGTACATATTGTAAAATAAACATGTTTTTTAACAT
GCTGTTGTA

hide sequence

RefSeq Acc Id:

XM_034952985 ⟹ XP_034808876

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	12	87,032,042 - 87,220,052 (+)	NCBI
NHGRI_mPanPan1	2A	87,036,045 - 87,224,027 (+)	NCBI
Mhudiblu_PPA_v0	2A	39,286,787 - 39,474,513 (-)	NCBI

RefSeq Acc Id:

XM_034952986 ⟹ XP_034808877

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	12	87,032,042 - 87,220,052 (+)	NCBI
NHGRI_mPanPan1	2A	87,036,046 - 87,224,027 (+)	NCBI
Mhudiblu_PPA_v0	2A	39,286,787 - 39,474,513 (-)	NCBI

RefSeq Acc Id:

XM_034952987 ⟹ XP_034808878

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	12	87,032,179 - 87,220,052 (+)	NCBI
NHGRI_mPanPan1	2A	87,036,265 - 87,224,027 (+)	NCBI
Mhudiblu_PPA_v0	2A	39,286,787 - 39,474,504 (-)	NCBI

RefSeq Acc Id:

XR_004669789

Type:

NON-CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	12	87,032,042 - 87,218,646 (+)	NCBI
NHGRI_mPanPan1	2A	87,036,036 - 87,222,621 (+)	NCBI
Mhudiblu_PPA_v0	2A	39,288,131 - 39,474,513 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003817676	(Get FASTA)	NCBI Sequence Viewer
	XP_003817677	(Get FASTA)	NCBI Sequence Viewer
	XP_034808876	(Get FASTA)	NCBI Sequence Viewer
	XP_034808877	(Get FASTA)	NCBI Sequence Viewer
	XP_034808878	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000013911.1
	ENSPPAP00000013916.1
	ENSPPAP00000013922.1
	ENSPPAP00000013927.1

RefSeq Acc Id:	XP_003817676 ⟸ XM_003817628
- Peptide Label:	isoform X4
- UniProtKB:	A0A2R9AAI7 (UniProtKB/TrEMBL), A0A2R9AEV1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIM MKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLH SKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYN QLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTK NPKKRPTAEKLLQHPFVTQHLTRSLAIELLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIHSTSR NVREEKTRSEINFGQVKFDPPLRKETEPHHELDLQLEYGQGHQGSYFLGANKSLLKSVEEELHQ RGHVAHLEDDEGDDDESKHSTLKAKVPPPLPPKPKSIFIPQEMHSTEDENQGTIKRCPMSGSPA KPSQVPPRPPPPRLPPHKPVALGNGMSSFQLNGERDGSLCQQQNEHRGTNLSRKEKKDIPKPIS NGLPPTPKVHMGACFSKVFNGCPLKIHCASSWINPDTRDQYLIFGAEEGIYTLNLNELHETSME QLFPRRCTWLYVMNNCLLSISGKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKFS VSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIDFPIPCPLRMF EMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTESDTPQTNVTHVTQLERDTILV CLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEIS DSTRIFRLLGSDRVVVLESRPTDNPTANSNLYILAGHENSY hide sequence

RefSeq Acc Id:	XP_003817677 ⟸ XM_003817629
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9AAI2 (UniProtKB/TrEMBL), A0A2R9AEV1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNPGFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIM MKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLH SKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYN QLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTK NPKKRPTAEKLLQHPFVTQHLTRSLAIELLDKVNNPDHSTYHDFDDDDPEPLVAVPHRIHSTSR NVREEKTRSEINFGQVKFDPPLRKETEPHHELPDSDGFLDSSEEIYYTARSNLDLQLEYGQGHQ GSYFLGANKSLLKSVEEELHQRGHVAHLEDDEGDDDESKHSTLKAKVPPPLPPKPKSIFIPQEM HSTEDENQGTIKRCPMSGSPAKPSQVPPRPPPPRLPPHKPVALGNGMSSFQLNGERDGSLCQQQ NEHRGTNLSRKEKKDIPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCASSWINPDTRDQYLI FGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSISGKASQLYSHNLPGLFDYARQMQ KLPVAIPAHKLPDRILPRKFSVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEP MQKFMLIKHIDFPIPCPLRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTE SDTPQTNVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLA FWKHGMQGRSFRSNEVTQEISDSTRIFRLLGSDRVVVLESRPTDNPTANSNLYILAGHENSY hide sequence

RefSeq Acc Id:	XP_034808877 ⟸ XM_034952986
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R9AEV1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034808876 ⟸ XM_034952985
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9AEV1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034808878 ⟸ XM_034952987
- Peptide Label:	isoform X5
- UniProtKB:	A0A2R9AEV1 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSPPAP00000013922 ⟸ ENSPPAT00000036597

Ensembl Acc Id:

ENSPPAP00000013916 ⟸ ENSPPAT00000036591

Ensembl Acc Id:

ENSPPAP00000013911 ⟸ ENSPPAT00000036586

Ensembl Acc Id:

ENSPPAP00000013927 ⟸ ENSPPAT00000036602

Protein Domains

CNH Protein kinase

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000030086	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000036586.1	UniProtKB/TrEMBL
	ENSPPAT00000036591.1	UniProtKB/TrEMBL
	ENSPPAT00000036597.1	UniProtKB/TrEMBL
	ENSPPAT00000036602.1	UniProtKB/TrEMBL
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/TrEMBL
InterPro	CNH_dom	UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/TrEMBL
	MAPKKKK	UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/TrEMBL
	STE20/SPS1-PAK	UniProtKB/TrEMBL
KEGG Report	pps:100971346	UniProtKB/TrEMBL
NCBI Gene	MAP4K3	ENTREZGENE
PANTHER	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE KINASE 3	UniProtKB/TrEMBL
	STERILE20-LIKE KINASE, ISOFORM B-RELATED	UniProtKB/TrEMBL
Pfam	CNH	UniProtKB/TrEMBL
	Pkinase	UniProtKB/TrEMBL
PIRSF	MAPKKKK	UniProtKB/TrEMBL
PROSITE	CNH	UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/TrEMBL
SMART	CNH	UniProtKB/TrEMBL
	S_TKc	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/TrEMBL
UniProt	A0A2R9AAI2	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9AAI7	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9AEV1	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9AEV5_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Annotations - PID (archival)