NAALAD2 (N-acetylated alpha-linked acidic dipeptidase 2) - Rat Genome Database

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Gene: NAALAD2 (N-acetylated alpha-linked acidic dipeptidase 2) Pan paniscus
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Symbol: NAALAD2
Name: N-acetylated alpha-linked acidic dipeptidase 2
RGD ID: 11771158
Description: ENCODES a protein that exhibits N-formylglutamate deformylase activity (ortholog); peptidase activity (ortholog); INVOLVED IN carboxylic acid catabolic process (ortholog); catabolic process (ortholog); proteolysis (ortholog); ASSOCIATED WITH intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100970655; N-acetylated-alpha-linked acidic dipeptidase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2990,948,253 - 91,006,340 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11192,034,951 - 92,093,003 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01185,105,296 - 85,163,280 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11188,600,918 - 88,658,985 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1188,600,918 - 88,658,985 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
NAALAD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2990,948,253 - 91,006,340 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11192,034,951 - 92,093,003 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01185,105,296 - 85,163,280 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11188,600,918 - 88,658,985 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1188,600,918 - 88,658,985 (+)Ensemblpanpan1.1panPan2
NAALAD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381190,131,699 - 90,192,894 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1190,131,515 - 90,192,894 (+)EnsemblGRCh38hg38GRCh38
GRCh371189,867,831 - 89,926,062 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361189,507,530 - 89,565,424 (+)NCBINCBI36Build 36hg18NCBI36
Build 341189,507,529 - 89,565,418NCBI
Celera1187,168,325 - 87,226,293 (+)NCBICelera
Cytogenetic Map11q14.3NCBI
HuRef1185,952,467 - 86,010,505 (+)NCBIHuRef
CHM1_11189,750,836 - 89,808,679 (+)NCBICHM1_1
T2T-CHM13v2.01190,051,780 - 90,112,974 (+)NCBIT2T-CHM13v2.0
Naalad2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39918,233,247 - 18,308,834 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl918,233,247 - 18,314,291 (-)EnsemblGRCm39 Ensembl
GRCm38918,321,951 - 18,397,538 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl918,321,951 - 18,402,995 (-)EnsemblGRCm38mm10GRCm38
MGSCv37918,127,465 - 18,190,372 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36918,073,423 - 18,136,330 (-)NCBIMGSCv36mm8
Celera915,606,315 - 15,669,553 (-)NCBICelera
Cytogenetic Map9A2NCBI
cM Map97.02NCBI
Naalad2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8823,682,499 - 23,756,066 (-)NCBIGRCr8
mRatBN7.2815,406,119 - 15,479,714 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl815,407,043 - 15,479,714 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx819,393,338 - 19,465,317 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0817,691,135 - 17,763,114 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0815,587,180 - 15,659,563 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0817,453,198 - 17,525,906 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl817,454,122 - 17,525,906 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0817,526,567 - 17,599,206 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4815,767,908 - 15,842,724 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1815,767,911 - 15,836,496 (-)NCBI
Celera816,835,457 - 16,908,126 (-)NCBICelera
Cytogenetic Map8q13NCBI
Naalad2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554143,728,596 - 3,791,706 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554143,728,596 - 3,789,265 (-)NCBIChiLan1.0ChiLan1.0
NAALAD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12110,162,323 - 10,222,990 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2110,162,578 - 10,253,015 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2110,054,329 - 10,119,513 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02110,339,550 - 10,404,777 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2110,343,608 - 10,435,065 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12110,138,437 - 10,197,311 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02110,193,157 - 10,258,556 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02110,243,380 - 10,308,589 (-)NCBIUU_Cfam_GSD_1.0
Naalad2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494775,689,202 - 75,735,773 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936893673,030 - 721,588 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936893672,380 - 716,440 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAALAD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl923,111,059 - 23,161,832 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1923,106,795 - 23,161,825 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2925,890,099 - 25,941,320 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NAALAD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1181,259,005 - 81,319,255 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl181,259,083 - 81,318,092 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604344,430,673 - 44,489,885 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Naalad2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624845252,042 - 298,864 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624845252,172 - 295,263 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000057864   ⟹   ENSPPAP00000034979
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1188,600,918 - 88,658,985 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000057872   ⟹   ENSPPAP00000034987
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1188,601,867 - 88,657,846 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000057875   ⟹   ENSPPAP00000034990
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1188,613,532 - 88,625,862 (+)Ensembl
RefSeq Acc Id: XM_008966381   ⟹   XP_008964629
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2990,948,253 - 91,006,340 (+)NCBI
NHGRI_mPanPan11192,034,951 - 92,093,003 (+)NCBI
Mhudiblu_PPA_v01185,105,296 - 85,163,280 (+)NCBI
PanPan1.11188,600,918 - 88,658,985 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008966382   ⟹   XP_008964630
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2990,948,253 - 91,006,340 (+)NCBI
NHGRI_mPanPan11192,034,951 - 92,093,003 (+)NCBI
Mhudiblu_PPA_v01185,105,297 - 85,163,280 (+)NCBI
PanPan1.11188,601,023 - 88,658,270 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034933529   ⟹   XP_034789420
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2990,948,253 - 91,006,340 (+)NCBI
NHGRI_mPanPan11192,034,951 - 92,093,003 (+)NCBI
Mhudiblu_PPA_v01185,105,297 - 85,163,280 (+)NCBI
RefSeq Acc Id: XM_034933530   ⟹   XP_034789421
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2990,948,253 - 91,006,340 (+)NCBI
NHGRI_mPanPan11192,034,951 - 92,093,003 (+)NCBI
Mhudiblu_PPA_v01185,105,585 - 85,163,280 (+)NCBI
RefSeq Acc Id: XM_034933531   ⟹   XP_034789422
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2990,948,255 - 91,006,340 (+)NCBI
NHGRI_mPanPan11192,034,953 - 92,093,003 (+)NCBI
Mhudiblu_PPA_v01185,105,298 - 85,163,280 (+)NCBI
RefSeq Acc Id: XP_008964629   ⟸   XM_008966381
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C9A7 (UniProtKB/TrEMBL),   A0A2R9BZ85 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008964630   ⟸   XM_008966382
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BZ85 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034789420   ⟸   XM_034933529
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BZ85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034789422   ⟸   XM_034933531
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BZ85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034789421   ⟸   XM_034933530
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BZ85 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSPPAP00000034979   ⟸   ENSPPAT00000057864
Ensembl Acc Id: ENSPPAP00000034990   ⟸   ENSPPAT00000057875
Ensembl Acc Id: ENSPPAP00000034987   ⟸   ENSPPAT00000057872

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000040316 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057864.1 UniProtKB/TrEMBL
  ENSPPAT00000057872.1 UniProtKB/TrEMBL
  ENSPPAT00000057875.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.930.40 UniProtKB/TrEMBL
  3.50.30.30 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro PA_dom_sf UniProtKB/TrEMBL
  PA_domain UniProtKB/TrEMBL
  Peptidase_M28 UniProtKB/TrEMBL
  Peptidase_M28B UniProtKB/TrEMBL
  TFR-like_dimer_dom UniProtKB/TrEMBL
  TFR-like_dimer_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100970655 UniProtKB/TrEMBL
NCBI Gene LOC100970655 ENTREZGENE
PANTHER N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE 2 UniProtKB/TrEMBL
  PTHR10404 UniProtKB/TrEMBL
Pfam Peptidase_M28 UniProtKB/TrEMBL
  PF02225 UniProtKB/TrEMBL
  TFR_dimer UniProtKB/TrEMBL
Superfamily-SCOP PA domain UniProtKB/TrEMBL
  SSF47672 UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A2R9BZ85 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C2G7_PANPA UniProtKB/TrEMBL
  A0A2R9C9A7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-07-01 NAALAD2  N-acetylated alpha-linked acidic dipeptidase 2  LOC100970655  N-acetylated-alpha-linked acidic dipeptidase 2  Symbol and/or name change 5135510 APPROVED