NAALAD2 (N-acetylated alpha-linked acidic dipeptidase 2) - Rat Genome Database

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Gene: NAALAD2 (N-acetylated alpha-linked acidic dipeptidase 2) Pan paniscus
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Symbol: NAALAD2
Name: N-acetylated alpha-linked acidic dipeptidase 2
RGD ID: 11771158
Description: ENCODES a protein that exhibits N-formylglutamate deformylase activity (ortholog); peptidase activity (ortholog); INVOLVED IN carboxylic acid catabolic process (ortholog); proteolysis (ortholog); ASSOCIATED WITH intellectual disability (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN membrane (inferred); plasma membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LOC100970655; N-acetylated-alpha-linked acidic dipeptidase 2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2990,948,253 - 91,006,340 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11192,034,951 - 92,093,003 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01185,105,296 - 85,163,280 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11188,600,918 - 88,658,985 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1188,600,918 - 88,658,985 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NAALAD2Bonobointellectual disability  ISORGD:13141648554872ClinVar Annotator: match by term: Intellectual disabilityClinVar 
NAALAD2BonoboNeurodevelopmental Disorders  ISORGD:13141648554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NAALAD2Bonobocarboxylic acid catabolic process involved_inISORGD:13141659068941 PMID:21908619MGIPMID:21908619
NAALAD2Bonoboproteolysis acts_upstream_of_or_withinISORGD:13141659068941 PMID:21908619MGIPMID:21908619

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NAALAD2Bonobomembrane located_inIEAUniProtKB-KW:KW-0472150520179 UniProtGO_REF:0000043
NAALAD2Bonoboplasma membrane located_inIEAUniProtKB-SubCell:SL-0039150520179 UniProtGO_REF:0000044

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
NAALAD2Bonobocarboxypeptidase activity enablesIEAPANTHER:PTN000044804|PANTHER:PTN000044806|PANTHER:PTN002572047150520179 TreeGrafterGO_REF:0000118
NAALAD2BonoboN-formylglutamate deformylase activity enablesISORGD:13141659068941 PMID:21908619MGIPMID:21908619
NAALAD2Bonobopeptidase activity enablesISORGD:13141659068941 PMID:15086519, PMID:21908619MGIPMID:15086519|PMID:21908619
NAALAD2Bonoboprotein binding enablesISOUniProtKB:O760249068941 PMID:32814053IntActPMID:32814053
NAALAD2Bonoboprotein binding enablesISOUniProtKB:B2RUZ4|UniProtKB:Q6NTF9-3|UniProtKB:Q9UHD49068941 PMID:32296183IntActPMID:32296183

PMID:30032202  



NAALAD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2990,948,253 - 91,006,340 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11192,034,951 - 92,093,003 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01185,105,296 - 85,163,280 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11188,600,918 - 88,658,985 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1188,600,918 - 88,658,985 (+)Ensemblpanpan1.1panPan2
NAALAD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381190,131,699 - 90,192,894 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1190,131,515 - 90,192,894 (+)EnsemblGRCh38hg38GRCh38
GRCh371189,867,831 - 89,926,062 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361189,507,530 - 89,565,424 (+)NCBINCBI36Build 36hg18NCBI36
Build 341189,507,529 - 89,565,418NCBI
Celera1187,168,325 - 87,226,293 (+)NCBICelera
Cytogenetic Map11q14.3NCBI
HuRef1185,952,467 - 86,010,505 (+)NCBIHuRef
CHM1_11189,750,836 - 89,808,679 (+)NCBICHM1_1
T2T-CHM13v2.01190,051,780 - 90,112,974 (+)NCBIT2T-CHM13v2.0
Naalad2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39918,233,247 - 18,308,834 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl918,233,247 - 18,314,291 (-)EnsemblGRCm39 Ensembl
GRCm38918,321,951 - 18,397,538 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl918,321,951 - 18,402,995 (-)EnsemblGRCm38mm10GRCm38
MGSCv37918,127,465 - 18,190,372 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36918,073,423 - 18,136,330 (-)NCBIMGSCv36mm8
Celera915,606,315 - 15,669,553 (-)NCBICelera
Cytogenetic Map9A2NCBI
cM Map97.02NCBI
Naalad2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8823,682,499 - 23,756,066 (-)NCBIGRCr8
mRatBN7.2815,406,119 - 15,479,714 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl815,407,043 - 15,479,714 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx819,393,338 - 19,465,317 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0817,691,135 - 17,763,114 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0815,587,180 - 15,659,563 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0817,453,198 - 17,525,906 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl817,454,122 - 17,525,906 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0817,526,567 - 17,599,206 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4815,767,908 - 15,842,724 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1815,767,911 - 15,836,496 (-)NCBI
Celera816,835,457 - 16,908,126 (-)NCBICelera
Cytogenetic Map8q13NCBI
Naalad2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554143,728,596 - 3,791,706 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554143,728,596 - 3,789,265 (-)NCBIChiLan1.0ChiLan1.0
NAALAD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12110,162,323 - 10,222,990 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2110,162,578 - 10,253,015 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2110,054,329 - 10,119,513 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02110,339,550 - 10,404,777 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2110,343,608 - 10,435,065 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12110,138,437 - 10,197,311 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02110,193,157 - 10,258,556 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02110,243,380 - 10,308,589 (-)NCBIUU_Cfam_GSD_1.0
Naalad2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494775,689,202 - 75,735,773 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936893673,030 - 721,588 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936893672,380 - 716,440 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NAALAD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl923,111,059 - 23,161,832 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1923,106,795 - 23,161,825 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2925,890,099 - 25,941,320 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NAALAD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1181,259,005 - 81,319,255 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl181,259,083 - 81,318,092 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604344,430,673 - 44,489,885 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Naalad2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624845252,042 - 298,864 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624845252,172 - 295,263 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.






Ensembl Acc Id: ENSPPAT00000057864   ⟹   ENSPPAP00000034979
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1188,600,918 - 88,658,985 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000057872   ⟹   ENSPPAP00000034987
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1188,601,867 - 88,657,846 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000057875   ⟹   ENSPPAP00000034990
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1188,613,532 - 88,625,862 (+)Ensembl
RefSeq Acc Id: XM_008966381   ⟹   XP_008964629
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2990,948,253 - 91,006,340 (+)NCBI
NHGRI_mPanPan11192,034,951 - 92,093,003 (+)NCBI
Mhudiblu_PPA_v01185,105,296 - 85,163,280 (+)NCBI
PanPan1.11188,600,918 - 88,658,985 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008966382   ⟹   XP_008964630
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2990,948,253 - 91,006,340 (+)NCBI
NHGRI_mPanPan11192,034,951 - 92,093,003 (+)NCBI
Mhudiblu_PPA_v01185,105,297 - 85,163,280 (+)NCBI
PanPan1.11188,601,023 - 88,658,270 (+)NCBI
Sequence:
RefSeq Acc Id: XM_034933529   ⟹   XP_034789420
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2990,948,253 - 91,006,340 (+)NCBI
NHGRI_mPanPan11192,034,951 - 92,093,003 (+)NCBI
Mhudiblu_PPA_v01185,105,297 - 85,163,280 (+)NCBI
RefSeq Acc Id: XM_034933530   ⟹   XP_034789421
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2990,948,253 - 91,006,340 (+)NCBI
NHGRI_mPanPan11192,034,951 - 92,093,003 (+)NCBI
Mhudiblu_PPA_v01185,105,585 - 85,163,280 (+)NCBI
RefSeq Acc Id: XM_034933531   ⟹   XP_034789422
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v2990,948,255 - 91,006,340 (+)NCBI
NHGRI_mPanPan11192,034,953 - 92,093,003 (+)NCBI
Mhudiblu_PPA_v01185,105,298 - 85,163,280 (+)NCBI
Protein RefSeqs XP_008964629 (Get FASTA)   NCBI Sequence Viewer  
  XP_008964630 (Get FASTA)   NCBI Sequence Viewer  
  XP_034789420 (Get FASTA)   NCBI Sequence Viewer  
  XP_034789421 (Get FASTA)   NCBI Sequence Viewer  
  XP_034789422 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000034979.1
  ENSPPAP00000034987.1
  ENSPPAP00000034990.1
RefSeq Acc Id: XP_008964629   ⟸   XM_008966381
- Peptide Label: isoform X1
- UniProtKB: A0A2R9C9A7 (UniProtKB/TrEMBL),   A0A2R9BZ85 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008964630   ⟸   XM_008966382
- Peptide Label: isoform X4
- UniProtKB: A0A2R9BZ85 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_034789420   ⟸   XM_034933529
- Peptide Label: isoform X2
- UniProtKB: A0A2R9BZ85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034789422   ⟸   XM_034933531
- Peptide Label: isoform X5
- UniProtKB: A0A2R9BZ85 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034789421   ⟸   XM_034933530
- Peptide Label: isoform X3
- UniProtKB: A0A2R9BZ85 (UniProtKB/TrEMBL)


1 to 26 of 26 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSPPAG00000040316 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000057864.1 UniProtKB/TrEMBL
  ENSPPAT00000057872.1 UniProtKB/TrEMBL
  ENSPPAT00000057875.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.930.40 UniProtKB/TrEMBL
  3.50.30.30 UniProtKB/TrEMBL
  Zn peptidases UniProtKB/TrEMBL
InterPro PA_dom_sf UniProtKB/TrEMBL
  PA_domain UniProtKB/TrEMBL
  Peptidase_M28 UniProtKB/TrEMBL
  Peptidase_M28B UniProtKB/TrEMBL
  TFR-like_dimer_dom UniProtKB/TrEMBL
  TFR-like_dimer_dom_sf UniProtKB/TrEMBL
KEGG Report pps:100970655 UniProtKB/TrEMBL
NCBI Gene LOC100970655 ENTREZGENE
PANTHER N-ACETYLATED-ALPHA-LINKED ACIDIC DIPEPTIDASE 2 UniProtKB/TrEMBL
  PTHR10404 UniProtKB/TrEMBL
Pfam Peptidase_M28 UniProtKB/TrEMBL
  PF02225 UniProtKB/TrEMBL
  TFR_dimer UniProtKB/TrEMBL
Superfamily-SCOP PA domain UniProtKB/TrEMBL
  SSF47672 UniProtKB/TrEMBL
  Zn-dependent exopeptidases UniProtKB/TrEMBL
UniProt A0A2R9BZ85 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9C2G7_PANPA UniProtKB/TrEMBL
  A0A2R9C9A7 ENTREZGENE, UniProtKB/TrEMBL
1 to 26 of 26 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-07-01 NAALAD2  N-acetylated alpha-linked acidic dipeptidase 2  LOC100970655  N-acetylated-alpha-linked acidic dipeptidase 2  Symbol and/or name change 5135510 APPROVED