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Gene: NRG3 (neuregulin 3) Pan paniscus

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Symbol:

NRG3

Name:

neuregulin 3

RGD ID:

11756651

Description:

ENCODES a protein that exhibits chemorepellent activity (inferred); growth factor activity (inferred); receptor ligand activity (inferred); INVOLVED IN chemorepulsion involved in interneuron migration from the subpallium to the cortex (ortholog); intracellular signal transduction (ortholog); mammary gland development (ortholog); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH Hirschsprung's disease (ortholog); schizophrenia (ortholog); FOUND IN extracellular space (ortholog); glutamatergic synapse (ortholog); synapse (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

pro-neuregulin-3, membrane-bound isoform

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NRG3 (neuregulin 3)	NCBI	Ortholog
Mus musculus (house mouse):	Nrg3 (neuregulin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Nrg3 (neuregulin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nrg3 (neuregulin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NRG3 (neuregulin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	LOC101957192 (pro-neuregulin-3, membrane-bound isoform)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NRG3 (neuregulin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NRG3 (neuregulin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nrg3 (neuregulin 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	93,833,755 - 94,981,643 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	93,839,076 - 94,986,963 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	78,267,693 - 79,384,895 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	81,862,024 - 82,974,743 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	81,862,036 - 82,973,334 (+)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Hirschsprung's disease (ISO)

schizophrenia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

animal organ development (IEA)

chemorepulsion involved in interneuron migration from the subpallium to the cortex (IEA,ISO)

ERBB4 signaling pathway (IEA)

ERBB4-ERBB4 signaling pathway (IEA)

intracellular signal transduction (IEA,ISO)

mammary gland development (IEA,ISO)

mammary placode formation (IEA,ISO)

modulation of chemical synaptic transmission (IEA)

negative chemotaxis (IEA)

negative regulation of neuron migration (IEA,ISO)

nervous system development (IEA)

pattern specification process (IEA,ISO)

synapse assembly (IEA)

Cellular Component

extracellular region (IEA)

extracellular space (IEA,ISO)

glutamatergic synapse (IEA,ISO)

membrane (IEA)

plasma membrane (IEA)

synapse (IEA,ISO)

Molecular Function

chemorepellent activity (IEA)

growth factor activity (IEA)

protein binding (ISO)

receptor ligand activity (IEA)

signaling receptor binding (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

epidermal growth factor/neuregulin signaling pathway (ISO)

References

Additional References at PubMed

PMID:30032202

Genomics

Comparative Map Data

NRG3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	93,833,755 - 94,981,643 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	93,839,076 - 94,986,963 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	78,267,693 - 79,384,895 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	81,862,024 - 82,974,743 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	10	81,862,036 - 82,973,334 (+)	Ensembl	panpan1.1		panPan2

NRG3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	81,875,194 - 82,987,179 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	81,875,194 - 82,987,179 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	10	83,634,950 - 84,746,935 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	83,625,077 - 84,735,341 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	10	77,630,757 - 78,742,147 (+)	NCBI		Celera
Cytogenetic Map	10	q23.1	NCBI
HuRef	10	77,483,814 - 78,594,633 (+)	NCBI		HuRef
CHM1_1	10	83,917,602 - 85,028,760 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	10	82,749,017 - 83,860,555 (+)	NCBI		T2T-CHM13v2.0

Nrg3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	38,086,093 - 39,195,045 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	38,090,909 - 39,195,045 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	38,365,102 - 39,473,235 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	38,368,952 - 39,473,088 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	39,182,137 - 40,286,376 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	37,282,204 - 38,384,967 (-)	NCBI		MGSCv36	mm8
Celera	14	34,560,237 - 35,661,300 (-)	NCBI		Celera
Cytogenetic Map	14	B	NCBI

Nrg3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	14,256,540 - 15,374,107 (-)	NCBI		GRCr8
mRatBN7.2	16	14,229,270 - 15,352,505 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	14,235,157 - 15,352,368 (-)	Ensembl		mRatBN7.2 Ensembl
Rnor_6.0	16	15,763,031 - 16,932,208 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	15,764,632 - 15,798,974 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	15,661,430 - 16,817,319 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	14,679,903 - 15,817,157 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	16	14,466,369 - 15,581,462 (-)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

Nrg3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955510	1,615,316 - 2,618,617 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955510	1,615,316 - 2,620,031 (+)	NCBI	ChiLan1.0	ChiLan1.0

NRG3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	30,515,845 - 31,557,598 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	30,515,890 - 31,556,152 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	30,570,501 - 31,546,936 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	30,834,334 - 31,875,634 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	30,834,349 - 31,874,016 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	30,699,630 - 31,739,836 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	30,896,586 - 31,931,272 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	31,385,545 - 32,426,952 (+)	NCBI		UU_Cfam_GSD_1.0

LOC101957192
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	49,019,288 - 50,047,975 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936716	1,362,574 - 2,391,432 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NRG3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	83,317,019 - 84,402,943 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	83,316,962 - 84,405,347 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	90,842,758 - 91,108,804 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NRG3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	48,846,287 - 49,957,238 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666048	9,110,091 - 10,240,887 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nrg3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624841	4,219,084 - 5,285,240 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624841	4,213,089 - 5,285,255 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008953559	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034930996	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034930997	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034930998	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034930999	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034931000	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034931001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034931002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034931003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034931004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034931005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034931006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034931007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055093079	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_055093080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057298945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057298946	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_057298947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063607483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000043786 ⟹ ENSPPAP00000020987

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	10	81,862,036 - 82,973,334 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000043792 ⟹ ENSPPAP00000020993

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	10	81,862,036 - 82,973,334 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000043803 ⟹ ENSPPAP00000021004

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	10	81,864,645 - 82,973,334 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000043806 ⟹ ENSPPAP00000021007

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	10	81,864,645 - 82,973,334 (+)	Ensembl

Ensembl Acc Id:

ENSPPAT00000043814 ⟹ ENSPPAP00000021015

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	10	82,939,183 - 82,973,334 (+)	Ensembl

RefSeq Acc Id:

XM_008953559 ⟹ XP_008951807

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,755 - 94,950,712 (+)	NCBI
NHGRI_mPanPan1	10	93,839,076 - 94,956,032 (+)	NCBI
Mhudiblu_PPA_v0	10	78,267,693 - 79,384,895 (+)	NCBI
PanPan1.1	10	81,862,024 - 82,974,743 (+)	NCBI

Sequence:

show sequence

CCGGCTCCTAGGATGAGTGAAGGGGCGGCCGCTGCCTCGCCACCTGGTGCCGCTTCGGCAGCCG
CCGCCTCGGCCGAGGAGGGCACCGCGGCGGCTGCGGCGGCGGCAGCGGCGGGCGGGGGCCCGGA
CGGCGGCGGCGAAGGGNCGGCCGAGCCCCCCCGGGAGTTACGCTGTAGCGACTGCATCGTGTGG
AACCGGCAGCAGACGTGGCTGTGCGTGGTACCTCTGTTCATCGGCTTCATCGGCCTGGGGCTCA
GCCTCATGCTTCTCAAATGGATCGTGGTGGGCTCCGTCAAGGAGTACGTGCCCACCGACCTAGT
GGACTCCAAGGGGATGGGCCAGGACCCCTTCTTCCTCTCCAAGCCCAGCTCTTTCCCCAAGGCC
ATGGAGACCACCACCACTACCACTTCCACCACGTCCCCCGCCACCCCCTCCGCCGGGGGTGCCG
CCTCCTCCAGGACGCCCAACCGGATTAGCACTCGCCTGACCACCATCACGCGGGCGCCCACTCG
CTTCCCCGGGCACCGGGTGCCCATCCGGGCCAGCCCGCGCTCCACCACAGCACGGAACACTGCG
GCCCCCGCGACGGTCCCGTCCACCACGGCCCCGTTCTTCAGTAGCAGCACGCCGGGCTCCCGAC
CCCCGGTGCCAGGAACTCCAAGTACCCAGGCAATGCCCTCCTGGCCTACTGCGGCATACGCTAC
CTCCTCCTACCTTCACGATTCTACTCCCTCCTGGACCCTGTCTCCCTTTCAGGATGCTGCCTCC
TCTTCTTCCTCTTCTTCCTCCTCCGCTACCACCACCACACCAGAAACTAGCACCAGCCCCAAAT
TTCATACGACGACATATTCCACAGAGCGATCCGAGCACTTCAAACCCTGCCGAGACAAGGACCT
TGCATACTGTCTCAATGATGGCGAGTGCTTTGTGATCGAAACCCTGACCGGATCCCATAAACAC
TGTCGGTGCAAAGAAGGCTACCAAGGAGTCCGTTGTGATCAATTTCTGCCGAAAACTGATTCCA
TCTTATCGGATCCAACAGACCACTTGGGGATTGAATTCATGGAGAGTGAAGAAGTTTATCAAAG
GCAGGTGCTGTCAATTTCATGTATCATCTTTGGAATTGTCATCGTGGGCATGTTCTGTGCAGCA
TTCTACTTCAAAAGCAAGAAACAAGCTAAACAAATCCAAGAGCAGCTGAAAGTGCCACAAAATG
GTAAAAGCTACAGTCTCAAAGCATCCAGCACAATGGCAAAGTCAGAGAACTTGGTGAAGAGCCA
TGTCCAGCTGCAAAATTATTCTAAGGTGGAAAGGCATCCTGTGACTGCATTGGAGAAAATGATG
GAGTCAAGTTTTGTCGGCCCCCAGTCATTCCCTGAGGTCCCTTCTCCTGACAGAGGAAGCCAGT
CTGTCAAACACCACAGGAGTCTATCCTCTTGCTGCAGCCCAGGGCAAAGAAGTGGCATGCTCCA
TAGGAATGCCTTCAGAAGGACACCCCCGTCACCCCGAAGTAGGCTAGGTGGAATTGTGGGACCA
GCATATCAGCAACTCGAAGAATCAAGGATCCCAGACCAGGATACGATACCTTGCCAAGGGATAG
AGGTCAGGAAGACTATATCCCACCTGCCTATACAGCTGTGGTGTGTTGAAAGACCCCTGGACTT
AAAGTATTCATCCAATGGTTTAAAAACCCAACGAAATACATCAATAAATATGCAACTGCCTTCA
AGAGAGACCAACCCCTATTTTAATAGCTTGGAGCAAAAGGACCTGGTGGGCTATTCATCCACAA
GGGCCAGTTCTGTGCCCATCATCCCTTCAGTGGGTTTAGAGGAAACCTGCCTGCAAATGCCAGG
GATTTCTGAAGTCAAAAGCATCAAATGGTGCAAAAACTCCTATTCAGCTGACGTTGTCAATGTG
AGTATTCCAGTCAGCGATTGTCTTATAGCAGAACAACAAGAAGTGAAAATATTGCTAGAAACTG
TCCAGGAGCAGATCCGAATTCTGACTGATGCCAGACGGTCAGAAGACTACGAACTGGCCAGTGT
AGAAACTGAGGACAGTGCAAGCGAAAACACAGCCTTTCTCCCCCTGAGTCCCACAGCCAAATCA
GAACGAGAGGCGCAATTTGTCTTAAGAAATGAAATACAAAGAGACTCTGCATTGACCAAGTGAC
TTGAGATGTAGGAATCCGTGCATTCTATGCTTTGCTCAACAGGAAAGAGAGGAAATCAAATACA
AATTATTTATATGCATTAATTTAAGAGCATCTACTTAGAAGAAACCAAATAGTCTATCGCCCTC
ATATCATAGTGTTTTTTAACAAAATATTTTTTTAAGGGAAAGAAATGTTTCAGGAGGGATAAAG
CTTACCATTAAAGCTTTTGGGTAGAATTCTGAATCCAATTTCGGTTAGTCCCAACACTGTCCTC
TTTGGCTCTTAGAAGATGTGGGCAATTCAGACCCTTGGCCCCACAGTGCCAGTGTCTCATTAAA
AAACACTGGCAGTTAACCTGGTTTCAAAAAGAGGAGAGCTGCATCCCGCAGGTGGATGCACCAG
TGAGCAGGTGGCCCTTGCCATTTGGCTTGCCAGTCCCAAGCCCTAAATTTCTATTCACCCAATA
GCCTCATCACAGGTTATGTCATGTCGACACATGTAGTGTTTTCTATTTGATTTTTGGAGAATGC
CACAAAATACTCTGCAATGGGAAGGAGGACAGGAGATAGAAGGAGAAACCGGGGGCAATCTTAA
CTACTCTTGTGTGCCACCTTCCTCTGAGATTTGAATGCACAGATCTCAGCTGGAGGTATGAAAT
TATTACAGAAAAAGAGACAAAAAAATCACTATATCGTGTCACTAAAATCATGCTAATAGAAATG
TTTTTCCTTGAGATTGTTTAGAGGCTCTGGAGGAGCGTTTCTCAGTTTTTGTGTGCCTGTGTGC
ACATGTGTGTGCGAGCGTGTGTGTGTGTGGACTTGCTCACGCGGGCACATATGCTGTAAGCACA
TGTGTTCATTGTGCGTATGTGTGTGCATGTGTGCGTGTATTACGCTTGCTAAAATTTGTTCTGA
AACATCAGGGAATCTAATATTCAGAAAAATATTTCCCTCTTAGATCTTTTCACTTTAAATTTTT
CCATTAAGTATAAAGTTCAGTTAGTTCTTAAATCAAGGTCACTTGCATGGTGGGGTCATATAAA
ACTCTTGACACTGTCTAGACCATTTTCTGATGTGAATACTTTTGAGAGGATCAACTATTGGCTC
ATTAATGATATCAGTATCATAAGGTGAGTTCACCGAGGATGTGTGTTTATTTTGAATCATGCCT
ACTTAAATTATTAATACAAGACAATTAACAAATTGACAGTTACCATTTGCTTTCTCATCATCCT
CATTACTATTTATTTTATAGCAAGTCTACTCTGTGTGGACCAAGGCTTTGGCTTCTGTGGTTAG
TATGGGAAGAACAAATTGTTGAAATAAAAATACCCAGACTATTCGGCTCACAAGAAGCCCCCCA
AAAGAACAGTAAATTGTGTTGTATGTTCATTTGGAATAAAGCAATATTTTTACCACTGCTAAGG

hide sequence

RefSeq Acc Id:

XM_034930996 ⟹ XP_034786887

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,802 - 94,950,712 (+)	NCBI
NHGRI_mPanPan1	10	93,839,123 - 94,956,032 (+)	NCBI
Mhudiblu_PPA_v0	10	78,267,740 - 79,384,895 (+)	NCBI

RefSeq Acc Id:

XM_034930997 ⟹ XP_034786888

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,802 - 94,950,712 (+)	NCBI
NHGRI_mPanPan1	10	93,839,124 - 94,956,032 (+)	NCBI
Mhudiblu_PPA_v0	10	78,267,741 - 79,384,895 (+)	NCBI

RefSeq Acc Id:

XM_034930998 ⟹ XP_034786889

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,802 - 94,950,712 (+)	NCBI
NHGRI_mPanPan1	10	93,839,123 - 94,956,032 (+)	NCBI
Mhudiblu_PPA_v0	10	78,267,740 - 79,384,895 (+)	NCBI

RefSeq Acc Id:

XM_034930999 ⟹ XP_034786890

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,802 - 94,950,712 (+)	NCBI
NHGRI_mPanPan1	10	93,839,124 - 94,956,032 (+)	NCBI
Mhudiblu_PPA_v0	10	78,267,741 - 79,384,895 (+)	NCBI

RefSeq Acc Id:

XM_034931000 ⟹ XP_034786891

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,802 - 94,950,712 (+)	NCBI
NHGRI_mPanPan1	10	93,839,125 - 94,956,032 (+)	NCBI
Mhudiblu_PPA_v0	10	78,267,742 - 79,384,895 (+)	NCBI

RefSeq Acc Id:

XM_034931003 ⟹ XP_034786894

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,802 - 94,950,712 (+)	NCBI
NHGRI_mPanPan1	10	93,839,124 - 94,956,032 (+)	NCBI
Mhudiblu_PPA_v0	10	78,267,741 - 79,384,895 (+)	NCBI

RefSeq Acc Id:

XM_034931004 ⟹ XP_034786895

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,755 - 94,950,712 (+)	NCBI
NHGRI_mPanPan1	10	93,839,076 - 94,956,032 (+)	NCBI
Mhudiblu_PPA_v0	10	78,267,693 - 79,384,895 (+)	NCBI

RefSeq Acc Id:

XM_034931005 ⟹ XP_034786896

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,755 - 94,950,712 (+)	NCBI
NHGRI_mPanPan1	10	93,839,076 - 94,956,032 (+)	NCBI
Mhudiblu_PPA_v0	10	78,267,693 - 79,384,895 (+)	NCBI

RefSeq Acc Id:

XM_034931006 ⟹ XP_034786897

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,802 - 94,950,712 (+)	NCBI
NHGRI_mPanPan1	10	93,839,128 - 94,956,032 (+)	NCBI
Mhudiblu_PPA_v0	10	78,267,744 - 79,384,895 (+)	NCBI

RefSeq Acc Id:

XM_055093079 ⟹ XP_054949054

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,802 - 94,980,569 (+)	NCBI
NHGRI_mPanPan1	10	93,839,123 - 94,985,898 (+)	NCBI

RefSeq Acc Id:

XM_055093080 ⟹ XP_054949055

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,802 - 94,981,643 (+)	NCBI
NHGRI_mPanPan1	10	93,839,123 - 94,986,963 (+)	NCBI

RefSeq Acc Id:

XM_057298945 ⟹ XP_057154928

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,802 - 94,950,712 (+)	NCBI
NHGRI_mPanPan1	10	93,839,124 - 94,956,032 (+)	NCBI

RefSeq Acc Id:

XM_057298946 ⟹ XP_057154929

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,802 - 94,950,712 (+)	NCBI
NHGRI_mPanPan1	10	93,839,125 - 94,956,032 (+)	NCBI

RefSeq Acc Id:

XM_057298947 ⟹ XP_057154930

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,755 - 94,385,608 (+)	NCBI
NHGRI_mPanPan1	10	93,839,076 - 94,390,929 (+)	NCBI

RefSeq Acc Id:

XM_063607483 ⟹ XP_063463553

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	8	93,833,802 - 94,965,467 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008951807	(Get FASTA)	NCBI Sequence Viewer
	XP_034786887	(Get FASTA)	NCBI Sequence Viewer
	XP_034786888	(Get FASTA)	NCBI Sequence Viewer
	XP_034786889	(Get FASTA)	NCBI Sequence Viewer
	XP_034786890	(Get FASTA)	NCBI Sequence Viewer
	XP_034786891	(Get FASTA)	NCBI Sequence Viewer
	XP_034786894	(Get FASTA)	NCBI Sequence Viewer
	XP_034786895	(Get FASTA)	NCBI Sequence Viewer
	XP_034786896	(Get FASTA)	NCBI Sequence Viewer
	XP_034786897	(Get FASTA)	NCBI Sequence Viewer
	XP_054949054	(Get FASTA)	NCBI Sequence Viewer
	XP_054949055	(Get FASTA)	NCBI Sequence Viewer
	XP_057154928	(Get FASTA)	NCBI Sequence Viewer
	XP_057154929	(Get FASTA)	NCBI Sequence Viewer
	XP_057154930	(Get FASTA)	NCBI Sequence Viewer
	XP_063463553	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000020987.1
	ENSPPAP00000020993.1
	ENSPPAP00000021004.1
	ENSPPAP00000021007.1
	ENSPPAP00000021015.1

RefSeq Acc Id:	XP_008951807 ⟸ XM_008953559
- Peptide Label:	isoform X9
- UniProtKB:	A0A2R9AUK1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSEGAAAASPPGAASAAAASAEEGTAAAAAAAAAGGGPDGGGEGXAEPPRELRCSDCIVWNRQQ TWLCVVPLFIGFIGLGLSLMLLKWIVVGSVKEYVPTDLVDSKGMGQDPFFLSKPSSFPKAMETT TTTTSTTSPATPSAGGAASSRTPNRISTRLTTITRAPTRFPGHRVPIRASPRSTTARNTAAPAT VPSTTAPFFSSSTPGSRPPVPGTPSTQAMPSWPTAAYATSSYLHDSTPSWTLSPFQDAASSSSS SSSSATTTTPETSTSPKFHTTTYSTERSEHFKPCRDKDLAYCLNDGECFVIETLTGSHKHCRCK EGYQGVRCDQFLPKTDSILSDPTDHLGIEFMESEEVYQRQVLSISCIIFGIVIVGMFCAAFYFK SKKQAKQIQEQLKVPQNGKSYSLKASSTMAKSENLVKSHVQLQNYSKVERHPVTALEKMMESSF VGPQSFPEVPSPDRGSQSVKHHRSLSSCCSPGQRSGMLHRNAFRRTPPSPRSRLGGIVGPAYQQ LEESRIPDQDTIPCQGIEVRKTISHLPIQLWCVERPLDLKYSSNGLKTQRNTSINMQLPSRETN PYFNSLEQKDLVGYSSTRASSVPIIPSVGLEETCLQMPGISEVKSIKWCKNSYSADVVNVSIPV SDCLIAEQQEVKILLETVQEQIRILTDARRSEDYELASVETEDSASENTAFLPLSPTAKSEREA QFVLRNEIQRDSALTK hide sequence

RefSeq Acc Id:	XP_034786895 ⟸ XM_034931004
- Peptide Label:	isoform X11
- UniProtKB:	A0A2R9AUW7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034786896 ⟸ XM_034931005
- Peptide Label:	isoform X12
- UniProtKB:	A0A2R9AUW7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034786887 ⟸ XM_034930996
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9AUK1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034786889 ⟸ XM_034930998
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R9AUK1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034786890 ⟸ XM_034930999
- Peptide Label:	isoform X4
- UniProtKB:	A0A2R9AUW7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034786888 ⟸ XM_034930997
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9AUK1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034786894 ⟸ XM_034931003
- Peptide Label:	isoform X8
- UniProtKB:	A0A2R9AUK1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034786891 ⟸ XM_034931000
- Peptide Label:	isoform X5
- UniProtKB:	A0A2R9AUW7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034786897 ⟸ XM_034931006
- Peptide Label:	isoform X13
- UniProtKB:	A0A2R9AUW7 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSPPAP00000021004 ⟸ ENSPPAT00000043803

Ensembl Acc Id:

ENSPPAP00000021007 ⟸ ENSPPAT00000043806

Ensembl Acc Id:

ENSPPAP00000021015 ⟸ ENSPPAT00000043814

Ensembl Acc Id:

ENSPPAP00000020993 ⟸ ENSPPAT00000043792

Ensembl Acc Id:

ENSPPAP00000020987 ⟸ ENSPPAT00000043786

RefSeq Acc Id:	XP_054949055 ⟸ XM_055093080
- Peptide Label:	isoform X15
- UniProtKB:	A0A2R9AUK1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_054949054 ⟸ XM_055093079
- Peptide Label:	isoform X14
- UniProtKB:	A0A2R9AUK1 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_057154930 ⟸ XM_057298947
- Peptide Label:	isoform X16

RefSeq Acc Id:	XP_057154928 ⟸ XM_057298945
- Peptide Label:	isoform X6
- UniProtKB:	A0A2R9AUW7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_057154929 ⟸ XM_057298946
- Peptide Label:	isoform X7
- UniProtKB:	A0A2R9AUW7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063463553 ⟸ XM_063607483
- Peptide Label:	isoform X10
- UniProtKB:	A0A2R9AUK1 (UniProtKB/TrEMBL)

Protein Domains

EGF-like

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000033661	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000043786.1	UniProtKB/TrEMBL
	ENSPPAT00000043792.1	UniProtKB/TrEMBL
	ENSPPAT00000043803.1	UniProtKB/TrEMBL
	ENSPPAT00000043806.1	UniProtKB/TrEMBL
	ENSPPAT00000043814.1	UniProtKB/TrEMBL
Gene3D-CATH	Laminin	UniProtKB/TrEMBL
InterPro	EGF-like_dom	UniProtKB/TrEMBL
	Neuregulin	UniProtKB/TrEMBL
NCBI Gene	NRG3	ENTREZGENE
PANTHER	PRO-NEUREGULIN-3, MEMBRANE-BOUND ISOFORM	UniProtKB/TrEMBL
	PTHR11100	UniProtKB/TrEMBL
PROSITE	EGF_1	UniProtKB/TrEMBL
	EGF_2	UniProtKB/TrEMBL
	EGF_3	UniProtKB/TrEMBL
Superfamily-SCOP	EGF/Laminin	UniProtKB/TrEMBL
UniProt	A0A2R9AUK1	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9AUM5_PANPA	UniProtKB/TrEMBL
	A0A2R9AUW7	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9AYU2_PANPA	UniProtKB/TrEMBL
	A0A2R9B0T7_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

RGD Manual Annotations

Imported Annotations - PID (archival)

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RGD Manual Annotations

Imported Annotations - PID (archival)