ARID3C (AT-rich interaction domain 3C)

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Gene: ARID3C (AT-rich interaction domain 3C) Pan paniscus

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Symbol:

ARID3C

Name:

AT-rich interaction domain 3C

RGD ID:

11752584

Description:

ENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); INVOLVED IN macrophage differentiation (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); ASSOCIATED WITH acromesomelic dysplasia, Maroteaux type (ortholog); anauxetic dysplasia (ortholog); autosomal recessive distal hereditary motor neuronopathy 2 (ortholog); FOUND IN nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

AT-rich interactive domain-containing protein 3C

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	89,974,694 - 89,982,711 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	89,975,061 - 89,989,017 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	34,457,638 - 34,466,425 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	35,267,063 - 35,275,057 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	35,267,063 - 35,275,057 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acromesomelic dysplasia, Maroteaux type (ISO)

anauxetic dysplasia (ISO)

autosomal recessive distal hereditary motor neuronopathy 2 (ISO)

distal arthrogryposis type 1A (ISO)

frontotemporal dementia and/or amyotrophic lateral sclerosis 6 (ISO)

galactosemia (ISO)

hyperphosphatasia with impaired intellectual development syndrome 2 (ISO)

paraplegia (ISO)

primary ciliary dyskinesia (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

macrophage differentiation (ISO)

positive regulation of transcription by RNA polymerase II (IEA,ISO)

regulation of transcription by RNA polymerase II (IEA)

Cellular Component

cytoplasm (IEA)

membrane raft (IEA)

nucleus (IEA,ISO)

Molecular Function

chromatin binding (IEA)

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (ISO)

protein binding (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ARID3C
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	11	89,974,694 - 89,982,711 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	9	89,975,061 - 89,989,017 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	9	34,457,638 - 34,466,425 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	9	35,267,063 - 35,275,057 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	35,267,063 - 35,275,057 (-)	Ensembl	panpan1.1		panPan2

ARID3C
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	34,621,049 - 34,633,011 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	9	34,621,049 - 34,629,066 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	34,621,046 - 34,629,063 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	34,611,455 - 34,618,011 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	9	34,552,959 - 34,559,515 (-)	NCBI		Celera
Cytogenetic Map	9	p13.3	NCBI
HuRef	9	34,575,737 - 34,582,294 (-)	NCBI		HuRef
CHM1_1	9	34,621,235 - 34,627,787 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	9	34,639,596 - 34,650,042 (-)	NCBI		T2T-CHM13v2.0

Arid3c
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	41,723,830 - 41,731,226 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	41,723,836 - 41,731,142 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	41,723,831 - 41,731,142 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	41,723,836 - 41,731,142 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	41,670,868 - 41,678,174 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	41,912,903 - 41,918,863 (-)	NCBI		MGSCv36	mm8
Celera	4	41,384,044 - 41,391,382 (-)	NCBI		Celera
Cytogenetic Map	4	A5	NCBI
cM Map	4	22.01	NCBI

Arid3c
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	61,685,511 - 61,692,821 (-)	NCBI		GRCr8
mRatBN7.2	5	56,889,649 - 56,896,959 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	56,890,042 - 56,895,888 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	58,869,550 - 58,875,393 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	60,688,382 - 60,694,225 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	60,674,253 - 60,680,097 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	58,107,182 - 58,114,632 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	58,107,707 - 58,113,553 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	62,631,772 - 62,637,618 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	59,148,421 - 59,154,267 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	5	55,484,083 - 55,489,929 (-)	NCBI		Celera
Cytogenetic Map	5	q22	NCBI

Arid3c
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955472	1,504,032 - 1,510,590 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955472	1,503,448 - 1,510,965 (+)	NCBI	ChiLan1.0	ChiLan1.0

ARID3C
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	11	51,294,605 - 51,301,979 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	11	51,295,030 - 51,301,547 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	11	49,922,506 - 49,930,320 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	11	52,234,892 - 52,242,709 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	11	52,235,759 - 52,242,279 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	11	50,897,603 - 50,905,422 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	11	50,765,803 - 50,773,609 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	11	51,530,526 - 51,538,340 (-)	NCBI		UU_Cfam_GSD_1.0

Arid3c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	166,157,164 - 166,165,371 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936524	2,705,121 - 2,711,557 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936524	2,705,112 - 2,711,557 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ARID3C
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	10	32,172,871 - 32,180,604 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	10	32,171,233 - 32,187,239 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	10	36,312,954 - 36,321,471 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Arid3c
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624736	39,016,483 - 39,023,668 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624736	39,016,483 - 39,023,701 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003829809	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034967350	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034967351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000055744 ⟹ ENSPPAP00000032873

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	9	35,267,063 - 35,275,057 (-)	Ensembl

RefSeq Acc Id:

XM_003829809 ⟹ XP_003829857

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	11	89,974,694 - 89,982,711 (+)	NCBI
NHGRI_mPanPan1	9	89,975,061 - 89,989,017 (+)	NCBI
Mhudiblu_PPA_v0	9	34,457,638 - 34,466,425 (-)	NCBI
PanPan1.1	9	35,267,063 - 35,275,057 (-)	NCBI

Sequence:

show sequence

CAGCGGGAGCGCACCGCCGGGACCCAGCCGAGGCCAGGGCCGCCTGGGAGGCGGGCGGAGCAAA
GGCAGCGCCGTGGAGACGCCAGGAGCAGCGGGCCACGCCAGGCAGGCGGCCCTTTCCTCGGGGT
CCCGCCTGGTACCAGGGACCCCCTCAGCTGGGGGACTGCGCCTGGAAGCTGTCATGGAGGCCCT
GCAGAAGCAGCAGGCAGCTCGGCTGGCCCAGGGGGTGGGGCCATTGGCCCCTGCATGCCCGCTG
CTGCCACCGCAGCCTCTCCTGCCTGACCACCGGACCCTACAGGCCCCTGAGGGGGCCTTGGGGA
ATGTTGGGGCTGAGGAAGAGGAAGATGCTGAAGAAGATGAGGAGAAGCGGGAGGAAGCCGGGGC
AGAGGAGGAGGCAGCTGAGGAGAGCCGTCCAGGGGCCCAGGGCCCCAGCTCGCCTTCTAGCCAG
CCCCCTGGACTCCATCCCCACGAGTGGACCTACGAGGAACAATTCAAGCAGCTGTATGAGCTCG
ATGCAGACCCCAAGAGGAAGGAATTTCTGGATGACCTGTTTAGCTTCATGCAAAAGAGGGGGAC
GCCAGTGAACCGCGTGCCCATCATGGCGAAGCAGGTGCTCGACCTGTACGCTCTGTTTCGCCTG
GTGACCGCCAAGGGCGGCCTGGTGGAAGTCATCAACCGCAAAGTGTGGCGGGAAGTCACGCGCG
GCCTCAGCCTACCCACCACCATCACCTCGGCCGCCTTCACTCTACGCACCCAGTACATGAAGTA
CCTGTACCCGTACGAGTGCGAGACTCGAGCGCTCAGCTCCCCAGGGGAGCTCCAGGCCGCCATA
GACAGCAATCGGCGCGAGGGCCGTCGCCAGGCTTACACCGCTACTCCGCTCTTCGGCTTGGCAG
GGCCGCCCCCTCGGGGCGCTCAGGACCCAGCCTTGGGTCCCGGCCCCGCCCCTCCGGCGACCCA
GTCCAGCCCTGGCCCAGCCCAGGGTTCCACCTCCGGCCTGCCAGCGCATGCATGCGCTCAGCTG
AGTCCAAGCCCTATTAAGAAAGAGGAGAGTGGAATTCCAAACCCTCGCCTGGCACTGCCTGTGG
GCCTGGCACTGGGACCTACACGGGAGAAATTGGCACCAGAGGAGCCCCCAGAGAAGAGAGCTGT
GCTGATGGGGCCTATGGACCCACCTCGACCTGGCATGCCCCCCAGTTTCCTGCCCCGTGGCAAG
GTTCCCCTGAGGGAAGAGCGGCTGGATGGGCCTCTTAATCTGGCAGGCAGTGGCATCAGCAGTA
TCAACATGGCCCTAGAGATCAACGGGGTGGTCTACACTGGTGTCCTCTTTGCCCGCCGCCAGCC
TGTGCCAGCTTCCCAGGGTCCAACCAACCCTGCACCCCCACCCTCCACAGGGCCCCCTTCCAGC
ATCTTGCCCTGAGAGGTCCTACTTGAAACTAAGAGTCCCAGCCCCATTGCTGAGGGGGGAGGAG
ACCCCCTGCTTTGATTCTTTCTGGCTGCCCACTCTGGGACCCAGCCCTGGGAGGGGACGACACC
TCCCATGCCATGTGGACTTAAAACCAAAGTTTCTTTTGATGTTACACCTACCTCATTGTAAAGG
GAGGGCATCTCCTCCCTGGCCAATTCCAGCAGCACCTACCAAAGGGTTCTTCCTCCAGTAACCC
CATCATCTCCTCATGTGTTACCTCTGTCAATGTCATCTCTAGGACCCTACCCTTTTGAGTCAGC
CCTGCTTCTCTTCAGGAGCCAAGTGAAAGGTTGGGTTGGGGTACTGTGAAAGAGACATCCCTCA
GGTCACATCTAGACAATAAAGCTGCGATCCCTCCCTC

hide sequence

Protein Sequences


Protein RefSeqs	XP_003829857	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000032873.1

RefSeq Acc Id:

XP_003829857 ⟸ XM_003829809

- UniProtKB:

A0A2R9BT85 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MEALQKQQAARLAQGVGPLAPACPLLPPQPLLPDHRTLQAPEGALGNVGAEEEEDAEEDEEKRE
EAGAEEEAAEESRPGAQGPSSPSSQPPGLHPHEWTYEEQFKQLYELDADPKRKEFLDDLFSFMQ
KRGTPVNRVPIMAKQVLDLYALFRLVTAKGGLVEVINRKVWREVTRGLSLPTTITSAAFTLRTQ
YMKYLYPYECETRALSSPGELQAAIDSNRREGRRQAYTATPLFGLAGPPPRGAQDPALGPGPAP
PATQSSPGPAQGSTSGLPAHACAQLSPSPIKKEESGIPNPRLALPVGLALGPTREKLAPEEPPE
KRAVLMGPMDPPRPGMPPSFLPRGKVPLREERLDGPLNLAGSGISSINMALEINGVVYTGVLFA
RRQPVPASQGPTNPAPPPSTGPPSSILP

hide sequence

Ensembl Acc Id:

ENSPPAP00000032873 ⟸ ENSPPAT00000055744

Protein Domains

ARID REKLES

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000039303	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000055744.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.150.60	UniProtKB/TrEMBL
InterPro	ARI3A/B/C	UniProtKB/TrEMBL
	ARID_dom	UniProtKB/TrEMBL
	ARID_dom_sf	UniProtKB/TrEMBL
	REKLES_domain	UniProtKB/TrEMBL
KEGG Report	pps:100976207	UniProtKB/TrEMBL
NCBI Gene	ARID3C	ENTREZGENE
PANTHER	AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 3C	UniProtKB/TrEMBL
	PTHR15348	UniProtKB/TrEMBL
Pfam	ARID	UniProtKB/TrEMBL
PROSITE	ARID	UniProtKB/TrEMBL
	REKLES	UniProtKB/TrEMBL
SMART	ARID	UniProtKB/TrEMBL
	BRIGHT	UniProtKB/TrEMBL
Superfamily-SCOP	SSF46774	UniProtKB/TrEMBL
UniProt	A0A2R9BT85	ENTREZGENE, UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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