FDFT1 (farnesyl-diphosphate farnesyltransferase 1)

Gene: FDFT1 (farnesyl-diphosphate farnesyltransferase 1) Pan paniscus

Analyze

Symbol:

FDFT1

Name:

farnesyl-diphosphate farnesyltransferase 1

RGD ID:

11720394

Description:

ENCODES a protein that exhibits farnesyl-diphosphate farnesyltransferase activity (ortholog); INVOLVED IN cholesterol biosynthetic process (ortholog); farnesyl diphosphate metabolic process (ortholog); PARTICIPATES IN alendronate pharmacodynamics pathway; cholesterol biosynthetic pathway; cholesterol ester storage disease pathway; ASSOCIATED WITH cannabis abuse (ortholog); cataract (ortholog); Cocaine-Related Disorders (ortholog); FOUND IN endoplasmic reticulum (inferred); endoplasmic reticulum membrane (inferred); membrane (inferred)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

squalene synthase

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	28,270,343 - 28,306,745 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	4,296,571 - 4,332,974 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	7,363,250 - 7,399,863 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cannabis abuse (ISO)

cataract (ISO)

Cocaine-Related Disorders (ISO)

genetic disease (ISO)

hepatocellular carcinoma (ISO)

Neurodevelopmental Disorders (ISO)

phencyclidine abuse (ISO)

Squalene Synthase Deficiency (ISO)

thoracic aortic aneurysm (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cholesterol biosynthetic process (IEA,ISO)

ergosterol biosynthetic process (IEA)

farnesyl diphosphate metabolic process (IEA,ISO)

lipid biosynthetic process (IEA)

Cellular Component

endoplasmic reticulum (IEA)

endoplasmic reticulum membrane (IEA)

membrane (IEA)

Molecular Function

farnesyl-diphosphate farnesyltransferase activity (IEA,ISO)

farnesyltranstransferase activity (IEA)

protein binding (ISO)

squalene synthase activity (IEA)

transferase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

alendronate pharmacodynamics pathway (ISO)

cholesterol biosynthetic pathway (ISO)

cholesterol ester storage disease pathway (ISO)

congenital hemidysplasia with ichthyosiform erythroderma and limb defects pathway (ISO)

desmosterolosis pathway (ISO)

hypercholesterolemia pathway (ISO)

ibandronate pharmacodynamics pathway (ISO)

mevalonic aciduria pathway (ISO)

nitrogenous bisphosphonate pharmacodynamics pathway (ISO)

pamidronate pharmacodynamics pathway (ISO)

risedronate pharmacodynamics pathway (ISO)

Smith-Lemli-Opitz Syndrome pathway (ISO)

statin pharmacodynamics pathway (ISO)

Wolman disease pathway (ISO)

X-linked dominant chondrodysplasia punctata 2 pathway (ISO)

zoledronate pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

FDFT1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	7	28,270,343 - 28,306,745 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	8	4,296,571 - 4,332,974 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	8	7,363,250 - 7,399,863 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

FDFT1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	11,795,582 - 11,839,309 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	8	11,795,573 - 11,839,395 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	11,653,091 - 11,696,818 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	11,697,599 - 11,734,227 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	11,697,663 - 11,734,215	NCBI
Celera	8	10,789,513 - 10,826,122 (+)	NCBI		Celera
Cytogenetic Map	8	p23.1	NCBI
HuRef	8	10,591,147 - 10,627,774 (+)	NCBI		HuRef
CHM1_1	8	11,725,653 - 11,762,299 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	7,900,999 - 7,944,714 (-)	NCBI		T2T-CHM13v2.0

Fdft1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	63,382,599 - 63,419,136 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	63,382,599 - 63,417,027 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	63,145,150 - 63,181,687 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	63,145,150 - 63,179,578 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	63,763,987 - 63,796,630 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	62,099,260 - 62,131,903 (-)	NCBI		MGSCv36	mm8
Celera	14	60,907,922 - 60,941,524 (-)	NCBI		Celera
Cytogenetic Map	14	D1	NCBI
cM Map	14	33.24	NCBI

Fdft1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	15	41,588,114 - 41,616,168 (-)	NCBI		GRCr8
mRatBN7.2	15	37,412,143 - 37,440,198 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	37,412,146 - 37,440,287 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	39,264,820 - 39,292,948 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	40,415,629 - 40,443,757 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	38,872,774 - 38,900,828 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	46,339,248 - 46,367,302 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	46,339,249 - 46,367,302 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	50,104,042 - 50,132,096 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	42,425,336 - 42,453,390 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	42,442,550 - 42,469,109 (-)	NCBI
Celera	15	37,096,417 - 37,124,524 (-)	NCBI		Celera
Cytogenetic Map	15	p12	NCBI

Fdft1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	53,067,637 - 53,081,499 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	53,068,011 - 53,081,499 (+)	NCBI	ChiLan1.0	ChiLan1.0

FDFT1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	26,060,031 - 26,093,515 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	26,060,386 - 26,093,582 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	26,717,027 - 26,750,517 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	26,215,096 - 26,248,206 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	26,212,580 - 26,248,141 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	26,160,696 - 26,194,180 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	26,064,844 - 26,097,943 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	26,216,048 - 26,249,367 (-)	NCBI		UU_Cfam_GSD_1.0

Fdft1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	61,589,408 - 61,590,034 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936628	3,599,435 - 3,600,061 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FDFT1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	14,967,074 - 15,016,227 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	14,976,259 - 15,010,701 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	16,164,964 - 16,199,406 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FDFT1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	7,272,580 - 7,306,859 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	7,271,509 - 7,306,760 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	35,129,389 - 35,164,015 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Fdft1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	25,340,074 - 25,366,299 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624758	25,340,142 - 25,363,669 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_003805315	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008969821	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034965606	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

XM_003805315 ⟹ XP_003805363

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	7	28,270,343 - 28,306,745 (+)	NCBI
NHGRI_mPanPan1	8	4,296,571 - 4,332,974 (+)	NCBI
Mhudiblu_PPA_v0	8	7,363,250 - 7,399,863 (-)	NCBI

Sequence:

show sequence

AATCAGTGCCCGTCAGCCCACCCCACGAGGCCGCAGGTAGCCCCGCTGGCGGCCGAGGCCGGTT
GAGTGGGCGGAGCGGCGGGCGGGGCGTCGCCGTACTAGGCCTGCCCCCTGTCCGGCCAGCCCCT
CGAAGCACCTACTCCACAGGTCCAGCCGGCCGGTGAGAGCCTGGGGACCGCAGAGGTGAGAGTC
GCGCCCGGGAGTCCGCCGCCTGCGCCAGGATGGAGTTCGTGAAATGCCTGGGCCACCCCGAAGA
GTTCTACAACCTGGTGCGCTTCCGGATCGGGGGCAAGCGGAAGGTGATGCCCAAGATGGACCAG
GACTCGCTCAGCAGCAGCCTGAAAACTTGCTACAAATATCTCAATCAGACCAGTCGCAGTTTCG
CAGCTGTTATCCAGGCGCTGGATGGGGAAATGCGCAACGCAGTTTGCATATTTTATCTGGTTCT
CCGAGCTCTGGACACACTGGAAGATGACATGACCATCAGTGTGGAAAAGAAGGTCCCGCTGTTA
CACAACTTTCACTCTTTCCTTTACCAACCAGACTGGCGGTTCATGGAGAGCAAGGAGAAGGATC
GCCAGGTGCTGGAGGACTTCCCAACGATCTCCCTTGAGTTTAGAAATCTGGCTGAGAAATACCA
AACAGTGATTGCCGACATTTGCCGGAGAATGGGCATTGGGATGGCAGAGTTTTTGGATAAGCAT
GTGACCTCTGAACAGGAGTGGGACAAGTACTGCCACTATGTTGCTGGGCTGGTCGGAATTGGCC
TTTCCCGTCTCTTCTCAGCCTCAGAGTTTGAAGACCCCTTAGTTGGTGAAGATACAGAACGTGC
CAACTCTATGGGCCTGTTTCTGCAGAAAACAAACATCATTCGTGACTATCTGGAAGACCAGCAA
GGAGGAAGAGAGTTCTGGCCTCAAGAGGTTTGGAGCAGGTATGTTAAGAAGTTAGGGGATTTTG
CTAAGCCGGAGAATATTGACTTGGCCGTGCAGTGCCTGAATGAACTTATAACCAATGCACTGCA
CCACATCCCAGATGTCATCACCTACCTTTCGAGACTCAGAAACCAGAGCGTGTTTAACTTCTGT
GCTATTCCACAGGTGATGGCCATTGCCACTTTGGCTGCCTGTTATAATAACCAGCAGGTGTTCA
AAGGGGCAGTGAAGATTCGGAAAGGGCAAGCAGTGACCCTGATGATGGATGCCACCAATATGCC
AGCTGTCAAAGCCATCATATATCAGTATATGGAAGAGATTTATCATAGAATCCCCGACTCAGAC
CCATCTTCTAGCAAAACAAGGCAGATCATCTCCACCATCCGGACACAGAATCTTCCCAACTGTC
AGCTGATTTCCCGAAGCCACTACTCCCCCATCTACCTGTCGTTTGTCATGCTCTTGGCTGCCCT
GAGCTGGCAGTACCTGACCACTCTCTCCCAGGTAACAGAAGACTATGTTCAGACTGGAGAACAC
TGATCCCAAATTTGTCCATAGCTGAAGTCCACCATAAAGTGGATTTACTTTTTTTCTTTAAGGA
TGGATGTTGTGTTTTCTTTATTTTTTCCTACTACTTTAATCCCTAAAAGAACGCTGTGTGGCTG
GGAACTTTAGGAAAGTGAAATGCAGGTGAGAAGAACCTAAACATGAAAGGAAAGGGTGCCTCAT
CCCAGCAACCTGTCCTTGTGGGTGATGATCACTGTGCTGCTTGTGGCTCATGGCAGAGCATTCA
GTGCCACGGTTTAGGTGAAGTCGCTGCATATGTGACTGTCATGAGATCCTACTTAGTATGATCC
TGGCTAGAATGATAATTAAAAGTATTTAATTTGAAGCACCATTTGAATGTTCGTAATAGTAGAA
AATGACGTGAATTTTCTTTCTGTTCGGCTCCTATTTTTCTCATCATTTTGTTTTCTTTAATTGG
GTTGAATGGAGTAGATAGAAATATTTATGGTTTAGGTAACAGTTAGATGTTTCCTAAGAGTGCA
AACTGCCTTTTCCACACAAAGGCTGGGAATAAACTTCTGGGTATTCTCGTATTCTCATTTAAAG
GAGTTTAGCTTTCAGAGAGAAACAGCAGGATTGCTTTTGACCTTTTAGAAGATTGGTCTCCAGT
AAAGGTGGACATTTTTGAGATTTTTATAATAAAGGATTTAATTGCTCTG

hide sequence

RefSeq Acc Id:

XM_008969821 ⟹ XP_008968069

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	7	28,270,614 - 28,306,745 (+)	NCBI
NHGRI_mPanPan1	8	4,296,842 - 4,332,974 (+)	NCBI
Mhudiblu_PPA_v0	8	7,363,250 - 7,399,711 (-)	NCBI

Sequence:

show sequence

ATGCCTGGGCCACCCCGAAGAGTTCTACAACCTGGTGCGCTTCCGGATCGGGGGCAAGCGGAAG
CCTCAGAGTTTGAAGACCCCTTAGTTGGTGAAGATACAGAACGTGCCAACTCTATGGGCCTGTT
TCTGCAGAAAACAAACATCATTCGTGACTATCTGGAAGACCAGCAAGGAGGAAGAGAGTTCTGG
CCTCAAGAGGTTTGGAGCAGGTATGTTAAGAAGTTAGGGGATTTTGCTAAGCCGGAGAATATTG
ACTTGGCCGTGCAGTGCCTGAATGAACTTATAACCAATGCACTGCACCACATCCCAGATGTCAT
CACCTACCTTTCGAGACTCAGAAACCAGAGCGTGTTTAACTTCTGTGCTATTCCACAGGTGATG
GCCATTGCCACTTTGGCTGCCTGTTATAATAACCAGCAGGTGTTCAAAGGGGCAGTGAAGATTC
GGAAAGGGCAAGCAGTGACCCTGATGATGGATGCCACCAATATGCCAGCTGTCAAAGCCATCAT
ATATCAGTATATGGAAGAGATTTATCATAGAATCCCCGACTCAGACCCATCTTCTAGCAAAACA
AGGCAGATCATCTCCACCATCCGGACACAGAATCTTCCCAACTGTCAGCTGATTTCCCGAAGCC
ACTACTCCCCCATCTACCTGTCGTTTGTCATGCTCTTGGCTGCCCTGAGCTGGCAGTACCTGAC
CACTCTCTCCCAGGTAACAGAAGACTATGTTCAGACTGGAGAACACTGATCCCAAATTTGTCCA
TAGCTGAAGTCCACCATAAAGTGGATTTACTTTTTTTCTTTAAGGATGGATGTTGTGTTTTCTT
TATTTTTTCCTACTACTTTAATCCCTAAAAGAACGCTGTGTGGCTGGGAACTTTAGGAAAGTGA
AATGCAGGTGAGAAGAACCTAAACATGAAAGGAAAGGGTGCCTCATCCCAGCAACCTGTCCTTG
TGGGTGATGATCACTGTGCTGCTTGTGGCTCATGGCAGAGCATTCAGTGCCACGGTTTAGGTGA
AGTCGCTGCATATGTGACTGTCATGAGATCCTACTTAGTATGATCCTGGCTAGAATGATAATTA
AAAGTATTTAATTTGAAGCACCATTTGAATGTTCGTAATAGTAGAAAATGACGTGAATTTTCTT
TCTGTTCGGCTCCTATTTTTCTCATCATTTTGTTTTCTTTAATTGGGTTGAATGGAGTAGATAG
AAATATTTATGGTTTAGGTAACAGTTAGATGTTTCCTAAGAGTGCAAACTGCCTTTTCCACACA
AAGGCTGGGAATAAACTTCTGGGTATTCTCGTATTCTCATTTAAAGGAGTTTAGCTTTCAGAGA
GAAACAGCAGGATTGCTTTTGACCTTTTAGAAGATTGGTCTCCAGTAAAGGTGGACATTTTTGA
GATTTTTATAATAAAGGATTTAATTGCTCTG

hide sequence

RefSeq Acc Id:

XM_034965606 ⟹ XP_034821497

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	7	28,276,244 - 28,306,745 (+)	NCBI
NHGRI_mPanPan1	8	4,302,483 - 4,332,974 (+)	NCBI
Mhudiblu_PPA_v0	8	7,363,250 - 7,394,070 (-)	NCBI

Protein Sequences


Protein RefSeqs	XP_003805363	(Get FASTA)	NCBI Sequence Viewer
	XP_008968069	(Get FASTA)	NCBI Sequence Viewer
	XP_034821497	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000012132.1
	ENSPPAP00000012147
	ENSPPAP00000012147.1
	ENSPPAP00000012164.1
	ENSPPAP00000012167.1
	ENSPPAP00000012168.1

RefSeq Acc Id:	XP_003805363 ⟸ XM_003805315
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9A4B7 (UniProtKB/TrEMBL), A0A2R9A4A0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEFVKCLGHPEEFYNLVRFRIGGKRKVMPKMDQDSLSSSLKTCYKYLNQTSRSFAAVIQALDGE MRNAVCIFYLVLRALDTLEDDMTISVEKKVPLLHNFHSFLYQPDWRFMESKEKDRQVLEDFPTI SLEFRNLAEKYQTVIADICRRMGIGMAEFLDKHVTSEQEWDKYCHYVAGLVGIGLSRLFSASEF EDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFWPQEVWSRYVKKLGDFAKPENIDLAV QCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVMAIATLAACYNNQQVFKGAVKIRKGQ AVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKTRQIISTIRTQNLPNCQLISRSHYSP IYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH hide sequence

RefSeq Acc Id:

XP_008968069 ⟸ XM_008969821

- Peptide Label:

isoform X3

- Sequence:

show sequence

MPGPPRRVLQPGALPDRGQAEASEFEDPLVGEDTERANSMGLFLQKTNIIRDYLEDQQGGREFW
PQEVWSRYVKKLGDFAKPENIDLAVQCLNELITNALHHIPDVITYLSRLRNQSVFNFCAIPQVM
AIATLAACYNNQQVFKGAVKIRKGQAVTLMMDATNMPAVKAIIYQYMEEIYHRIPDSDPSSSKT
RQIISTIRTQNLPNCQLISRSHYSPIYLSFVMLLAALSWQYLTTLSQVTEDYVQTGEH

hide sequence

RefSeq Acc Id:	XP_034821497 ⟸ XM_034965606
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9A4D7 (UniProtKB/TrEMBL)

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000029259	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000034794.1	UniProtKB/TrEMBL
	ENSPPAT00000034809.1	UniProtKB/TrEMBL
	ENSPPAT00000034826.1	UniProtKB/TrEMBL
	ENSPPAT00000034829.1	UniProtKB/TrEMBL
	ENSPPAT00000034830.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.600.10	UniProtKB/TrEMBL
InterPro	Isoprenoid_synthase_dom_sf	UniProtKB/TrEMBL
	Squ/phyt_synthse	UniProtKB/TrEMBL
	Squal_synth-like	UniProtKB/TrEMBL
	Squalene/phytoene_synthase_CS	UniProtKB/TrEMBL
	Trans_IPPS_euk-type	UniProtKB/TrEMBL
	Trans_IPPS_HH	UniProtKB/TrEMBL
KEGG Report	pps:100987932	UniProtKB/TrEMBL
NCBI Gene	FDFT1	ENTREZGENE
PANTHER	PTHR11626	UniProtKB/TrEMBL
	SQUALENE SYNTHASE	UniProtKB/TrEMBL
Pfam	SQS_PSY	UniProtKB/TrEMBL
PROSITE	SQUALEN_PHYTOEN_SYN_1	UniProtKB/TrEMBL
	SQUALEN_PHYTOEN_SYN_2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48576	UniProtKB/TrEMBL
UniProt	A0A2R9A4A0	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9A4B7	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9A4D7	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9A4E9_PANPA	UniProtKB/TrEMBL
	A0A2R9A5K6_PANPA	UniProtKB/TrEMBL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB

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Imported Disease Annotations - ClinVar

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Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB