COP1 (COP1 E3 ubiquitin ligase) - Rat Genome Database

Name: COP1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: COP1 (COP1 E3 ubiquitin ligase) Pan paniscus

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Symbol:

COP1

Name:

COP1 E3 ubiquitin ligase

RGD ID:

11710963

Description:

ENCODES a protein that exhibits metal ion binding (inferred); ubiquitin protein ligase activity (inferred); INVOLVED IN positive regulation of proteasomal ubiquitin-dependent protein catabolic process (inferred); proteasome-mediated ubiquitin-dependent protein catabolic process (inferred); response to ionizing radiation (inferred); PARTICIPATES IN p53 signaling pathway; ASSOCIATED WITH 1q24 Deletion Syndrome (ortholog); antithrombin III deficiency (ortholog); autistic disorder (ortholog); FOUND IN Golgi membrane (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

COP1, E3 ubiquitin ligase; E3 ubiquitin-protein ligase COP1; RFWD2; ring finger and WD repeat domain 2

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	COP1 (COP1 E3 ubiquitin ligase)	NCBI	Ortholog
Mus musculus (house mouse):	Cop1 (COP1, E3 ubiquitin ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Cop1 (COP1, E3 ubiquitin ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Cop1 (COP1 E3 ubiquitin ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	COP1 (COP1 E3 ubiquitin ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Cop1 (COP1 E3 ubiquitin ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	COP1 (COP1 E3 ubiquitin ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	COP1 (COP1 E3 ubiquitin ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Cop1 (COP1 E3 ubiquitin ligase)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly

Position:

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	73,506,205 - 73,784,010 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	73,186,486 - 73,457,341 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	151,459,354 - 151,727,131 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	155,155,860 - 155,425,664 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	155,156,185 - 155,425,156 (-)	Ensembl	panpan1.1		panPan2

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

1q24 Deletion Syndrome (ISO)

antithrombin III deficiency (ISO)

autistic disorder (ISO)

gastrointestinal stromal tumor (ISO)

parathyroid carcinoma (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

positive regulation of proteasomal ubiquitin-dependent protein catabolic process (IEA)

proteasome-mediated ubiquitin-dependent protein catabolic process (IEA)

response to ionizing radiation (IEA)

Cellular Component

Cul4A-RING E3 ubiquitin ligase complex (IEA)

Golgi membrane (ISO)

Molecular Function

metal ion binding (IEA)

protein binding (ISO)

ubiquitin protein ligase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

p53 signaling pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

COP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	73,506,205 - 73,784,010 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	73,186,486 - 73,457,341 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	151,459,354 - 151,727,131 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	155,155,860 - 155,425,664 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	155,156,185 - 155,425,156 (-)	Ensembl	panpan1.1		panPan2

COP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	175,944,831 - 176,207,286 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	175,944,831 - 176,207,286 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	175,913,967 - 176,176,422 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	174,180,590 - 174,442,993 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	172,645,624 - 172,908,027	NCBI
Celera	1	149,024,694 - 149,287,018 (-)	NCBI		Celera
Cytogenetic Map	1	q25.1-q25.2	NCBI
HuRef	1	147,140,664 - 147,403,100 (-)	NCBI		HuRef
CHM1_1	1	177,337,538 - 177,600,480 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	175,300,159 - 175,562,553 (-)	NCBI		T2T-CHM13v2.0

Cop1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	159,059,734 - 159,182,442 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	159,059,890 - 159,175,210 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	159,232,156 - 159,354,872 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	159,232,320 - 159,347,640 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	161,162,457 - 161,277,711 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	161,069,003 - 161,184,257 (+)	NCBI		MGSCv36	mm8
Celera	1	161,631,243 - 161,748,921 (+)	NCBI		Celera
Cytogenetic Map	1	H1	NCBI
cM Map	1	69.03	NCBI

Cop1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	73,954,058 - 74,095,283 (+)	NCBI		GRCr8
mRatBN7.2	13	71,467,164 - 71,561,826 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	71,429,961 - 71,538,890 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	74,044,221 - 74,138,940 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	75,344,334 - 75,439,013 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	72,603,700 - 72,698,383 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	76,942,883 - 77,076,015 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	76,942,928 - 77,075,723 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	81,853,391 - 81,986,197 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	74,552,876 - 74,590,608 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	74,979,314 - 74,981,857 (-)	NCBI
Celera	13	71,277,941 - 71,371,841 (+)	NCBI		Celera
Cytogenetic Map	13	q22	NCBI

Cop1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	15,662,546 - 15,859,306 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	15,662,546 - 15,859,306 (-)	NCBI	ChiLan1.0	ChiLan1.0

COP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	23,320,483 - 23,565,093 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	23,277,209 - 23,563,397 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	22,845,782 - 23,088,376 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	7	23,068,997 - 23,312,240 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	7	23,069,323 - 23,326,866 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	7	22,980,843 - 23,224,152 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	7	23,074,250 - 23,317,391 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	7	23,217,346 - 23,460,833 (+)	NCBI		UU_Cfam_GSD_1.0

Cop1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	94,415,666 - 94,590,738 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936481	12,262,409 - 12,437,571 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936481	12,262,415 - 12,437,627 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

COP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	117,915,443 - 118,114,259 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	117,913,504 - 118,114,268 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	129,664,173 - 129,764,054 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

COP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	53,057,479 - 53,316,662 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	25	53,057,784 - 53,314,398 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666055	54,611,740 - 54,870,873 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cop1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624771	5,922,067 - 6,133,597 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624771	5,922,086 - 6,132,537 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_008978351	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034941231	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034941236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034941240	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034941244	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_034941252	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063598396	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063598401	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063598407	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JARIFH020000001	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSPPAT00000037408 ⟹ ENSPPAP00000014721

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	155,156,185 - 155,425,156 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000037418 ⟹ ENSPPAP00000014731

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	155,207,408 - 155,425,156 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000037421 ⟹ ENSPPAP00000014734

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	155,365,647 - 155,425,156 (-)	Ensembl

Ensembl Acc Id:

ENSPPAT00000037424 ⟹ ENSPPAP00000014737

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
PanPan1.1 Ensembl	1	155,367,343 - 155,425,156 (-)	Ensembl

RefSeq Acc Id:

XM_008978351 ⟹ XP_008976599

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	73,506,208 - 73,784,010 (+)	NCBI
NHGRI_mPanPan1	1	73,186,486 - 73,457,341 (+)	NCBI
Mhudiblu_PPA_v0	1	151,459,354 - 151,727,131 (-)	NCBI
PanPan1.1	1	155,155,860 - 155,425,664 (-)	NCBI

Sequence:

show sequence

ATACCATTCATTCCAGTCTCCTCAATTCTTTCACTGTATTAAGACGGCCTGCCCTCTGGCACGT
TTTCTGGAACGAAAGCGGCTTGGGACAGACAGACTCCCTTCGCCAGGGAGCCCCGACCCCGAGG
GCGCGCCCTGAGCGTCTGAGCGCAGCCCTGCTGCGTCCCCAGTTGTATCCCCCGCCACGCCCGC
CTCTTCCGCCGCTCGCGCGCGCGCGCACGGCCGGCCACGGCGCGCCGGGGTTGGCTGCTACAGG
GACCGCGACGGCGGCGGCCTGGACAGCGGTAGTACCTTCTACTCCGCTTTTTTAGTTTCCTCCG
CCCCCTCCCGTGGGACGCTGTTGTGTGGTTGCCTTAAAAAAAAAACGCAACTTTATTGTTCCTC
AGCCCCACCTCCGGCTCGGCGGGCGTCCTCAGGATGCACTGAGGCTGAGGGGAGGGGAGGCGGC
GGAGGGTCGAGGTCGCGGTCCCTCTCCTCCGAGCGCCCGGCTGGAGGGGAGGGAGTCACGATGT
CTGGTAGCCGCCAGGCCGGGTCGGGCTCCGCTGGGACAAGCCCCGGCTCCTCGGCGGCCTCCTC
GGTGACTTCCGCCTCCTCGTCTTTATCCTCTTCCCCGTCGCCGCCTTCCGTGGCGGTTTCGGCG
GCAGCGCTGGTGTCCGGCGGGGTGGCCCAGGCCGCCGGCTCGGGCGGCCTCGGGGGCCCGGTGC
GGCCTGTGTTGGTGGCGCCCGCCGTATCGGGCAGCGGCGGCGGGGCGGTGTCCACGGGCCTGTC
CCGGCACAGCTGCGCGGCCAGGCCCAGCGCCGGCGTAGGAGGCAGCAGCTCCAGCCTAGGCAGC
GGCAGCAGGAAGCGACCTCTGCTCGCCCCCCTCTGCAACGGGCTCATCAACTCCTACGAGGACA
AAAGCAACGACTTCGTATGCCCCATCTGCTTTGATATGATTGAAGAAGCATACATGACAAAATG
TGGCCACAGCTTTTGCTACAAGTGTATTCATCAGAGTTTGGAGGACAATAATAGATGTCCCAAG
TGTAACTATGTTGTGGACAATATTGACCATCTGTATCCTAATTTCTTGGTGAATGAACTCATTC
TTAAACAGAAGCAAAGATTTGAGGAAAAGAGGTTCAAATTGGACCACTCAGTGAGTAGCACCAA
TGGCCACAGGTGGCAGATATTTCAAGATTGGTTGGGAACTGACCAAGATAACCTTGATTTGGCC
AATGTCAATCTTATGTTGGAGTTACTAGTGCAGAAGAAGAAACAACTGGAAGCAGAATCACATG
CAGCCCAACTACAGATTCTTATGGAATTCCTCAAGGTTGCAAGAAGAAATAAGAGAGAGCAACT
GGAACAGATCCAGAAGGAGCTAAGTGTTTTGGAAGAGGATATTAAGAGAGTGGAAGAAATGAGT
GGCTTATACTCTCCTGTCAGTGAGGATAGCACAGTGCCTCAATTTGAAGCTCCTTCTCCATCAC
ACAGTAGTATTATTGATTCCACAGAATACAGCCAACCTCCAGGTTTCAGTGGCAGTTCTCAGAC
AAAGAAACAGCCTTGGTATAATAGCACATTAGCATCAAGACGAAAACGACTTACTGCTCATTTT
GAAGACTTGGAGCAGTGTTACTTTTCTACAAGGATGTCTCGTATCTCAGATGACAGTCGAACTG
CAAGCCAGTTGGATGAATTTCAGGAATGCTTGTCCAAGTTTACTCGATATAATTCAGTACGACC
TTTAGCCACATTGTCATATGCTAGTGATCTCTATAATGGTTCCAGTATAGTCTCTAGTATTGAA
TTTGACCGGGATTGTGACTATTTTGCGATTGCTGGAGTTACAAAGAAGATTAAAGTCTATGAAT
ATGACACTGTCATCCAGGATGCAGTGGATATTCATTACCCTGAGAATGAAATGACCTGCAATTC
GAAAATCAGCTGTATCAGTTGGAGTAGTTACCATAAGAACCTGTTAGCTAGCAGTGATTATGAA
GGCACTGTTATTTTATGGGATGGATTCACAGGACAGAGGTCAAAGGTCTATCAGGAGCATGAGA
AGAGGTGTTGGAGTGTTGACTTTAATTTGATGGATCCTAAACTCTTGGCTTCAGGTTCTGATGA
TGCAAAAGTGAAGCTGTGGTCTACCAATCTAGACAACTCAGTGGCAAGCATTGAGGCAAAGGCT
AATGTGTGCTGTGTTAAATTCAGCCCCTCTTCCCGATACCATTTGGCTTTCGGCTGTGCAGATC
ACTGTGTCCACTACTATGATCTTCGTAACACTAAACAGCCAATCATGGTATTCAAAGGACACCG
TAAAGCAGTCTCTTATGCAAAGTTTGTGAGTGGTGAGGAAATTGTCTCTGCCTCAACAGACAGT
CAGCTAAAACTGTGGAATGTAGGGAAACCATACTGCCTACGTTCCTTCAAGGGTCATATCAATN
GAAAAAACTTTGTAGGCCTGGCTTCCAATGGAGATTATATAGCTTGTGGAAGTGAAAATAACTC
TCTCTACCTGTACTATAAAGGACTTTCTAAGACTTTGCTAACTTTTAAGTTTGATACAGTCAAA
AGTGTTCTGGACAAAGACCGAAAAGAAGATGATACAAATGAATTTGTTAGTGCTGTGTGCTGGA
GGGCACTACCAGATGGGGAGTCCAATGTGCTGATTGCTGCTAACAGTCAGGGTACAATTAAGGT
GCTAGAATTGGTATGAAGGGTTAACTCAAGTCAAATTGTACTTGATCCTGCTGAAATACATCTG
CAGCTGACAATGAGAGAAGAAACAGAAAATGTCATGTGATGTCTCTCCCCAAAGTCATCATGGG
TTTTGGATTTGTTTTGAATATTTTTTTCTTTTTTTCTTTTCCCTCCTTTATGACCTTTGGGACA
TTGGGAATACCCAGCCAACTCTCCACCATCAATGTAACTCCATGGACATTGCTGCTCTTGGTGG
TGTTGTTATCTAATTTTTGTGATAGGGAAACAAATTCTTTTGAATAAAAATAAATAACAAAAAA
AATAAAAGTTTATTGAGCCAC

hide sequence

RefSeq Acc Id:

XM_034941231 ⟹ XP_034797122

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	73,506,206 - 73,784,010 (+)	NCBI
NHGRI_mPanPan1	1	73,186,523 - 73,457,341 (+)	NCBI
Mhudiblu_PPA_v0	1	151,459,354 - 151,727,086 (-)	NCBI

RefSeq Acc Id:

XM_034941236 ⟹ XP_034797127

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	73,506,206 - 73,784,010 (+)	NCBI
NHGRI_mPanPan1	1	73,186,717 - 73,457,341 (+)	NCBI
Mhudiblu_PPA_v0	1	151,459,354 - 151,727,086 (-)	NCBI

RefSeq Acc Id:

XM_034941240 ⟹ XP_034797131

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	73,506,205 - 73,784,010 (+)	NCBI
NHGRI_mPanPan1	1	73,186,714 - 73,457,341 (+)	NCBI
Mhudiblu_PPA_v0	1	151,459,354 - 151,727,089 (-)	NCBI

RefSeq Acc Id:

XM_034941252 ⟹ XP_034797143

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	73,516,874 - 73,784,010 (+)	NCBI
NHGRI_mPanPan1	1	73,187,289 - 73,457,341 (+)	NCBI
Mhudiblu_PPA_v0	1	151,459,354 - 151,726,554 (-)	NCBI

RefSeq Acc Id:

XM_063598396 ⟹ XP_063454466

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	73,506,206 - 73,784,010 (+)	NCBI

RefSeq Acc Id:

XM_063598401 ⟹ XP_063454471

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	73,506,210 - 73,784,010 (+)	NCBI

RefSeq Acc Id:

XM_063598407 ⟹ XP_063454477

Type:

CODING

Position:

Bonobo Assembly	Chr	Position (strand)	Source
NHGRI_mPanPan1-v2	1	73,538,841 - 73,784,010 (+)	NCBI

Protein Sequences


Protein RefSeqs	XP_008976599	(Get FASTA)	NCBI Sequence Viewer
	XP_034797122	(Get FASTA)	NCBI Sequence Viewer
	XP_034797127	(Get FASTA)	NCBI Sequence Viewer
	XP_034797131	(Get FASTA)	NCBI Sequence Viewer
	XP_034797143	(Get FASTA)	NCBI Sequence Viewer
	XP_063454466	(Get FASTA)	NCBI Sequence Viewer
	XP_063454471	(Get FASTA)	NCBI Sequence Viewer
	XP_063454477	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSPPAP00000014721.1
	ENSPPAP00000014731.1
	ENSPPAP00000014734.1
	ENSPPAP00000014737.1

RefSeq Acc Id:	XP_008976599 ⟸ XM_008978351
- Peptide Label:	isoform X1
- UniProtKB:	A0A2R9ACT7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSGSRQAGSGSAGTSPGSSAASSVTSASSSLSSSPSPPSVAVSAAALVSGGVAQAAGSGGLGGP VRPVLVAPAVSGSGGGAVSTGLSRHSCAARPSAGVGGSSSSLGSGSRKRPLLAPLCNGLINSYE DKSNDFVCPICFDMIEEAYMTKCGHSFCYKCIHQSLEDNNRCPKCNYVVDNIDHLYPNFLVNEL ILKQKQRFEEKRFKLDHSVSSTNGHRWQIFQDWLGTDQDNLDLANVNLMLELLVQKKKQLEAES HAAQLQILMEFLKVARRNKREQLEQIQKELSVLEEDIKRVEEMSGLYSPVSEDSTVPQFEAPSP SHSSIIDSTEYSQPPGFSGSSQTKKQPWYNSTLASRRKRLTAHFEDLEQCYFSTRMSRISDDSR TASQLDEFQECLSKFTRYNSVRPLATLSYASDLYNGSSIVSSIEFDRDCDYFAIAGVTKKIKVY EYDTVIQDAVDIHYPENEMTCNSKISCISWSSYHKNLLASSDYEGTVILWDGFTGQRSKVYQEH EKRCWSVDFNLMDPKLLASGSDDAKVKLWSTNLDNSVASIEAKANVCCVKFSPSSRYHLAFGCA DHCVHYYDLRNTKQPIMVFKGHRKAVSYAKFVSGEEIVSASTDSQLKLWNVGKPYCLRSFKGHI NXKNFVGLASNGDYIACGSENNSLYLYYKGLSKTLLTFKFDTVKSVLDKDRKEDDTNEFVSAVC WRALPDGESNVLIAANSQGTIKVLELV hide sequence

RefSeq Acc Id:	XP_034797131 ⟸ XM_034941240
- Peptide Label:	isoform X5
- UniProtKB:	A0A2R9ACT7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034797122 ⟸ XM_034941231
- Peptide Label:	isoform X2
- UniProtKB:	A0A2R9ACT7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034797127 ⟸ XM_034941236
- Peptide Label:	isoform X3
- UniProtKB:	A0A2R9ACT7 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_034797143 ⟸ XM_034941252
- Peptide Label:	isoform X8

Ensembl Acc Id:

ENSPPAP00000014737 ⟸ ENSPPAT00000037424

Ensembl Acc Id:

ENSPPAP00000014734 ⟸ ENSPPAT00000037421

Ensembl Acc Id:

ENSPPAP00000014731 ⟸ ENSPPAT00000037418

Ensembl Acc Id:

ENSPPAP00000014721 ⟸ ENSPPAT00000037408

RefSeq Acc Id:	XP_063454466 ⟸ XM_063598396
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_063454471 ⟸ XM_063598401
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_063454477 ⟸ XM_063598407
- Peptide Label:	isoform X7

Protein Domains

RING-type

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSPPAG00000030430	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSPPAT00000037408.1	UniProtKB/TrEMBL
	ENSPPAT00000037418.1	UniProtKB/TrEMBL
	ENSPPAT00000037421.1	UniProtKB/TrEMBL
	ENSPPAT00000037424.1	UniProtKB/TrEMBL
Gene3D-CATH	2.130.10.10	UniProtKB/TrEMBL
	3.30.40.10	UniProtKB/TrEMBL
InterPro	COP1	UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/TrEMBL
	WD40_repeat_CS	UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/TrEMBL
	Znf_RING	UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/TrEMBL
	Znf_RING_CS	UniProtKB/TrEMBL
NCBI Gene	RFWD2	ENTREZGENE
PANTHER	E3 UBIQUITIN-PROTEIN LIGASE COP1	UniProtKB/TrEMBL
	PTHR44080	UniProtKB/TrEMBL
Pfam	WD40	UniProtKB/TrEMBL
	zf-C3HC4_2	UniProtKB/TrEMBL
PROSITE	WD_REPEATS_1	UniProtKB/TrEMBL
	WD_REPEATS_2	UniProtKB/TrEMBL
	ZF_RING_1	UniProtKB/TrEMBL
	ZF_RING_2	UniProtKB/TrEMBL
SMART	RING	UniProtKB/TrEMBL
	WD40	UniProtKB/TrEMBL
Superfamily-SCOP	RING/U-box	UniProtKB/TrEMBL
	SSF50978	UniProtKB/TrEMBL
UniProt	A0A2R9ABU5_PANPA	UniProtKB/TrEMBL
	A0A2R9ACT7	ENTREZGENE, UniProtKB/TrEMBL
	A0A2R9ACU6_PANPA	UniProtKB/TrEMBL
	A0A2R9AHL8_PANPA	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-01-29	COP1	COP1 E3 ubiquitin ligase		COP1, E3 ubiquitin ligase	Symbol and/or name change	5135510	APPROVED
2017-12-19	COP1	COP1, E3 ubiquitin ligase	RFWD2	ring finger and WD repeat domain 2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)