PIK3IP1 (phosphoinositide-3-kinase interacting protein 1) - Rat Genome Database

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Gene: PIK3IP1 (phosphoinositide-3-kinase interacting protein 1) Pan paniscus
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Symbol: PIK3IP1
Name: phosphoinositide-3-kinase interacting protein 1
RGD ID: 11697900
Description: ENCODES a protein that exhibits phosphatidylinositol 3-kinase inhibitor activity (inferred); INVOLVED IN negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (inferred); ASSOCIATED WITH diastolic heart failure (ortholog); FOUND IN membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphoinositide-3-kinase-interacting protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22341,237,436 - 41,248,185 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12243,935,910 - 43,946,741 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02212,305,518 - 12,316,434 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12230,141,326 - 30,152,397 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2230,141,326 - 30,152,397 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
PIK3IP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22341,237,436 - 41,248,185 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12243,935,910 - 43,946,741 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02212,305,518 - 12,316,434 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12230,141,326 - 30,152,397 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2230,141,326 - 30,152,397 (-)Ensemblpanpan1.1panPan2
PIK3IP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382231,281,593 - 31,292,534 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2231,281,594 - 31,292,534 (-)EnsemblGRCh38hg38GRCh38
GRCh372231,677,579 - 31,688,520 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362230,007,579 - 30,018,474 (-)NCBINCBI36Build 36hg18NCBI36
Celera2215,478,064 - 15,489,008 (-)NCBICelera
Cytogenetic Map22q12.2NCBI
HuRef2214,639,191 - 14,650,132 (-)NCBIHuRef
CHM1_12231,637,394 - 31,648,335 (-)NCBICHM1_1
T2T-CHM13v2.02231,745,576 - 31,756,513 (-)NCBIT2T-CHM13v2.0
Pik3ip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,280,731 - 3,292,971 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,280,401 - 3,292,971 (+)EnsemblGRCm39 Ensembl
GRCm38113,319,241 - 3,342,971 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,330,401 - 3,342,971 (+)EnsemblGRCm38mm10GRCm38
MGSCv37113,230,734 - 3,242,974 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,230,810 - 3,242,974 (+)NCBIMGSCv36mm8
Celera113,821,671 - 3,833,939 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.33NCBI
Pik3ip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81482,428,315 - 82,440,261 (+)NCBIGRCr8
mRatBN7.21478,204,668 - 78,216,616 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,204,053 - 78,216,608 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1482,645,643 - 82,657,589 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01483,885,757 - 83,897,703 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01480,331,495 - 80,343,441 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01483,559,397 - 83,572,481 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1483,560,541 - 83,572,473 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01484,247,648 - 84,260,753 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41483,955,895 - 83,967,828 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11483,975,039 - 83,986,972 (+)NCBI
Celera1477,118,136 - 77,130,069 (+)NCBICelera
Cytogenetic Map14q21NCBI
Pik3ip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554555,476,095 - 5,488,265 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554555,474,569 - 5,488,420 (-)NCBIChiLan1.0ChiLan1.0
PIK3IP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12624,243,195 - 24,255,335 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2624,244,772 - 24,255,131 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2624,113,213 - 24,125,201 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02624,626,590 - 24,638,613 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2624,623,419 - 24,638,555 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12624,329,790 - 24,341,795 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02624,591,664 - 24,603,676 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02624,653,292 - 24,665,310 (-)NCBIUU_Cfam_GSD_1.0
Pik3ip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118117,188,262 - 117,198,541 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936755445,894 - 457,386 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936755444,264 - 456,071 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIK3IP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1448,040,881 - 48,051,660 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11448,040,848 - 48,051,660 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21451,151,820 - 51,162,619 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIK3IP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11914,169,738 - 14,183,329 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1914,171,243 - 14,183,350 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045111,934,068 - 111,947,507 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pik3ip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247477,767,802 - 7,779,725 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247477,767,823 - 7,779,675 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000033354   ⟹   ENSPPAP00000010701
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2230,141,326 - 30,152,397 (-)Ensembl
Ensembl Acc Id: ENSPPAT00000033357   ⟹   ENSPPAP00000010704
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl2230,141,326 - 30,152,397 (-)Ensembl
RefSeq Acc Id: XM_003826927   ⟹   XP_003826975
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22341,237,436 - 41,248,185 (-)NCBI
NHGRI_mPanPan12243,935,910 - 43,946,741 (-)NCBI
Mhudiblu_PPA_v02212,305,518 - 12,316,399 (-)NCBI
PanPan1.12230,141,326 - 30,152,397 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008952277   ⟹   XP_008950525
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22341,237,436 - 41,248,135 (-)NCBI
NHGRI_mPanPan12243,935,910 - 43,946,740 (-)NCBI
Mhudiblu_PPA_v02212,305,518 - 12,316,434 (-)NCBI
PanPan1.12230,141,326 - 30,152,397 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_003826975 (Get FASTA)   NCBI Sequence Viewer  
  XP_008950525 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSPPAP00000010701
  ENSPPAP00000010701.1
  ENSPPAP00000010704
  ENSPPAP00000010704.1
RefSeq Acc Id: XP_008950525   ⟸   XM_008952277
- Peptide Label: isoform X2
- UniProtKB: A0A2R9A4N9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_003826975   ⟸   XM_003826927
- Peptide Label: isoform X1
- UniProtKB: A0A2R9A0C3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSPPAP00000010704   ⟸   ENSPPAT00000033357
Ensembl Acc Id: ENSPPAP00000010701   ⟸   ENSPPAT00000033354
Protein Domains
Kringle


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000028563 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000033354.1 UniProtKB/TrEMBL
  ENSPPAT00000033357.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.20.10 UniProtKB/TrEMBL
InterPro Kringle UniProtKB/TrEMBL
  Kringle-like UniProtKB/TrEMBL
  Kringle_CS UniProtKB/TrEMBL
  Kringle_sf UniProtKB/TrEMBL
  Serine_protease_kringle UniProtKB/TrEMBL
KEGG Report pps:100978866 UniProtKB/TrEMBL
NCBI Gene PIK3IP1 ENTREZGENE
PANTHER PHOSPHOINOSITIDE-3-KINASE-INTERACTING PROTEIN 1 UniProtKB/TrEMBL
  PLASMINOGEN-RELATED UniProtKB/TrEMBL
Pfam Kringle UniProtKB/TrEMBL
PROSITE KRINGLE_1 UniProtKB/TrEMBL
  KRINGLE_2 UniProtKB/TrEMBL
SMART SM00130 UniProtKB/TrEMBL
Superfamily-SCOP SSF57440 UniProtKB/TrEMBL
UniProt A0A2R9A0C3 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9A4N9 ENTREZGENE, UniProtKB/TrEMBL