PIK3IP1 (phosphoinositide-3-kinase interacting protein 1) - Rat Genome Database

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Gene: PIK3IP1 (phosphoinositide-3-kinase interacting protein 1) Sus scrofa
Analyze
Symbol: PIK3IP1
Name: phosphoinositide-3-kinase interacting protein 1
RGD ID: 14108532
Description: ENCODES a protein that exhibits endopeptidase activity (inferred); phosphatidylinositol 3-kinase catalytic subunit binding (inferred); phosphatidylinositol 3-kinase inhibitor activity (inferred); INVOLVED IN negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (inferred); ASSOCIATED WITH diastolic heart failure (ortholog); genetic disease (ortholog); FOUND IN extracellular space (inferred); plasma membrane (inferred); INTERACTS WITH deoxynivalenol
Type: protein-coding
RefSeq Status: MODEL
Previously known as: phosphoinositide-3-kinase-interacting protein 1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1448,040,881 - 48,051,660 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11448,040,848 - 48,051,660 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21451,151,820 - 51,162,619 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:14681463  


Genomics

Comparative Map Data
PIK3IP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1448,040,881 - 48,051,660 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11448,040,848 - 48,051,660 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21451,151,820 - 51,162,619 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PIK3IP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382231,281,593 - 31,292,534 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2231,281,594 - 31,292,534 (-)EnsemblGRCh38hg38GRCh38
GRCh372231,677,579 - 31,688,520 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362230,007,579 - 30,018,474 (-)NCBINCBI36Build 36hg18NCBI36
Celera2215,478,064 - 15,489,008 (-)NCBICelera
Cytogenetic Map22q12.2NCBI
HuRef2214,639,191 - 14,650,132 (-)NCBIHuRef
CHM1_12231,637,394 - 31,648,335 (-)NCBICHM1_1
T2T-CHM13v2.02231,745,576 - 31,756,513 (-)NCBIT2T-CHM13v2.0
Pik3ip1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39113,280,731 - 3,292,971 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl113,280,401 - 3,292,971 (+)EnsemblGRCm39 Ensembl
GRCm38113,319,241 - 3,342,971 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl113,330,401 - 3,342,971 (+)EnsemblGRCm38mm10GRCm38
MGSCv37113,230,734 - 3,242,974 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36113,230,810 - 3,242,974 (+)NCBIMGSCv36mm8
Celera113,821,671 - 3,833,939 (+)NCBICelera
Cytogenetic Map11A1NCBI
cM Map112.33NCBI
Pik3ip1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81482,428,315 - 82,440,261 (+)NCBIGRCr8
mRatBN7.21478,204,668 - 78,216,616 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1478,204,053 - 78,216,608 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1482,645,643 - 82,657,589 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01483,885,757 - 83,897,703 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01480,331,495 - 80,343,441 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01483,559,397 - 83,572,481 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1483,560,541 - 83,572,473 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01484,247,648 - 84,260,753 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41483,955,895 - 83,967,828 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11483,975,039 - 83,986,972 (+)NCBI
Celera1477,118,136 - 77,130,069 (+)NCBICelera
Cytogenetic Map14q21NCBI
Pik3ip1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554555,476,095 - 5,488,265 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554555,474,569 - 5,488,420 (-)NCBIChiLan1.0ChiLan1.0
PIK3IP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22341,237,436 - 41,248,185 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12243,935,910 - 43,946,741 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02212,305,518 - 12,316,434 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12230,141,326 - 30,152,397 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2230,141,326 - 30,152,397 (-)Ensemblpanpan1.1panPan2
PIK3IP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12624,243,195 - 24,255,335 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2624,244,772 - 24,255,131 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2624,113,213 - 24,125,201 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02624,626,590 - 24,638,613 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2624,623,419 - 24,638,555 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12624,329,790 - 24,341,795 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02624,591,664 - 24,603,676 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02624,653,292 - 24,665,310 (-)NCBIUU_Cfam_GSD_1.0
Pik3ip1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118117,188,262 - 117,198,541 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936755445,894 - 457,386 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936755444,264 - 456,071 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PIK3IP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11914,169,738 - 14,183,329 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1914,171,243 - 14,183,350 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666045111,934,068 - 111,947,507 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pik3ip1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247477,767,802 - 7,779,725 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247477,767,823 - 7,779,675 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PIK3IP1
121 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 3 1 3 13 1 2
Low 7 3 3 2 2 10 2 2 1
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000010983   ⟹   ENSSSCP00000010697
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1448,040,881 - 48,051,660 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000086905   ⟹   ENSSSCP00000064039
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1448,042,795 - 48,051,395 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000106457   ⟹   ENSSSCP00000081295
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl1448,041,536 - 48,051,660 (-)Ensembl
RefSeq Acc Id: XM_001926534   ⟹   XP_001926569
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11448,040,848 - 48,051,660 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013983076   ⟹   XP_013838530
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.11448,040,848 - 48,051,481 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_001926569   ⟸   XM_001926534
- Peptide Label: isoform X2
- UniProtKB: F1RPC1 (UniProtKB/TrEMBL),   A0A4X1V910 (UniProtKB/TrEMBL),   A0A8D0TBQ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_013838530   ⟸   XM_013983076
- Peptide Label: isoform X1
- UniProtKB: A0A8D1GNM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000010697   ⟸   ENSSSCT00000010983
RefSeq Acc Id: ENSSSCP00000064039   ⟸   ENSSSCT00000086905
RefSeq Acc Id: ENSSSCP00000081295   ⟸   ENSSSCT00000106457
Protein Domains
Kringle


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000010026 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00015080996 UniProtKB/TrEMBL
  ENSSSCG00025069129 UniProtKB/TrEMBL
  ENSSSCG00030021287 UniProtKB/TrEMBL
  ENSSSCG00035036805 UniProtKB/TrEMBL
  ENSSSCG00040006888 UniProtKB/TrEMBL
  ENSSSCG00045003818 UniProtKB/TrEMBL
  ENSSSCG00050076797 UniProtKB/TrEMBL
  ENSSSCG00055008523 UniProtKB/TrEMBL
  ENSSSCG00060069665 UniProtKB/TrEMBL
  ENSSSCG00065039221 UniProtKB/TrEMBL
  ENSSSCG00070022705 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000010983 ENTREZGENE
  ENSSSCT00000010983.5 UniProtKB/TrEMBL
  ENSSSCT00000086905.1 UniProtKB/TrEMBL
  ENSSSCT00000106457.1 UniProtKB/TrEMBL
  ENSSSCT00015110356.1 UniProtKB/TrEMBL
  ENSSSCT00025094977.1 UniProtKB/TrEMBL
  ENSSSCT00025095102.1 UniProtKB/TrEMBL
  ENSSSCT00025095185.1 UniProtKB/TrEMBL
  ENSSSCT00025095321.1 UniProtKB/TrEMBL
  ENSSSCT00025095386.1 UniProtKB/TrEMBL
  ENSSSCT00030029521.1 UniProtKB/TrEMBL
  ENSSSCT00035048780.1 UniProtKB/TrEMBL
  ENSSSCT00035048784.1 UniProtKB/TrEMBL
  ENSSSCT00035048787.1 UniProtKB/TrEMBL
  ENSSSCT00035048789.1 UniProtKB/TrEMBL
  ENSSSCT00040009054.1 UniProtKB/TrEMBL
  ENSSSCT00040009061.1 UniProtKB/TrEMBL
  ENSSSCT00040009065.1 UniProtKB/TrEMBL
  ENSSSCT00040009075.1 UniProtKB/TrEMBL
  ENSSSCT00045006318.1 UniProtKB/TrEMBL
  ENSSSCT00045006323.1 UniProtKB/TrEMBL
  ENSSSCT00045006330.1 UniProtKB/TrEMBL
  ENSSSCT00045006338.1 UniProtKB/TrEMBL
  ENSSSCT00050105572.1 UniProtKB/TrEMBL
  ENSSSCT00055016650.1 UniProtKB/TrEMBL
  ENSSSCT00055016666.1 UniProtKB/TrEMBL
  ENSSSCT00055016700.1 UniProtKB/TrEMBL
  ENSSSCT00055016729.1 UniProtKB/TrEMBL
  ENSSSCT00060095135.1 UniProtKB/TrEMBL
  ENSSSCT00065053610.1 UniProtKB/TrEMBL
  ENSSSCT00065053612.1 UniProtKB/TrEMBL
  ENSSSCT00065053619.1 UniProtKB/TrEMBL
  ENSSSCT00065053621.1 UniProtKB/TrEMBL
  ENSSSCT00070045137.1 UniProtKB/TrEMBL
  ENSSSCT00070045140.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.20.10 UniProtKB/TrEMBL
InterPro Kringle UniProtKB/TrEMBL
  Kringle-like UniProtKB/TrEMBL
  Kringle_CS UniProtKB/TrEMBL
  Kringle_sf UniProtKB/TrEMBL
KEGG Report ssc:100155147 UniProtKB/TrEMBL
NCBI Gene PIK3IP1 ENTREZGENE
PANTHER PHOSPHOINOSITIDE-3-KINASE-INTERACTING PROTEIN 1 UniProtKB/TrEMBL
  PLASMINOGEN-RELATED UniProtKB/TrEMBL
Pfam Kringle UniProtKB/TrEMBL
PROSITE KRINGLE_1 UniProtKB/TrEMBL
  KRINGLE_2 UniProtKB/TrEMBL
SMART SM00130 UniProtKB/TrEMBL
Superfamily-SCOP SSF57440 UniProtKB/TrEMBL
UniProt A0A4X1V8S1_PIG UniProtKB/TrEMBL
  A0A4X1V910 ENTREZGENE, UniProtKB/TrEMBL
  A0A5G2QPN7_PIG UniProtKB/TrEMBL
  A0A8D0TBQ2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0TIQ1_PIG UniProtKB/TrEMBL
  A0A8D0ZRG5_PIG UniProtKB/TrEMBL
  A0A8D1GJ57_PIG UniProtKB/TrEMBL
  A0A8D1GNM2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4FQ07_PIG UniProtKB/TrEMBL
  F1RPC1 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:91444 ENTREZGENE