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Gene: PIK3IP1 (phosphoinositide-3-kinase interacting protein 1) Homo sapiens
Symbol: PIK3IP1
Name: phosphoinositide-3-kinase interacting protein 1
Description: Exhibits phosphatidylinositol 3-kinase catalytic subunit binding activity. Involved in negative regulation of phosphatidylinositol 3-kinase activity and negative regulation of phosphatidylinositol 3-kinase signaling. Predicted to localize to integral component of membrane and plasma membrane; INTERACTS WITH 17beta-estradiol; aflatoxin B2; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HGFL; hHGFL(S); kringle domain-containing protein HGFL; MGC17330; phosphoinositide-3-kinase-interacting protein 1; transmembrane inhibitor of PI3K; TrIP
Mus musculus (house mouse) : Pik3ip1 (phosphoinositide-3-kinase interacting protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pik3ip1 (phosphoinositide-3-kinase interacting protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pik3ip1 (phosphoinositide-3-kinase interacting protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PIK3IP1 (phosphoinositide-3-kinase interacting protein 1)
Canis lupus familiaris (dog) : PIK3IP1 (phosphoinositide-3-kinase interacting protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pik3ip1 (phosphoinositide-3-kinase interacting protein 1)
Sus scrofa (pig) : PIK3IP1 (phosphoinositide-3-kinase interacting protein 1)
Chlorocebus sabaeus (African green monkey) : PIK3IP1 (phosphoinositide-3-kinase interacting protein 1)
Heterocephalus glaber (naked mole-rat) : Pik3ip1 (phosphoinositide-3-kinase interacting protein 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2231,281,594 - 31,292,534 (-)EnsemblGRCh38hg38GRCh38
GRCh382231,281,593 - 31,292,534 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372231,677,579 - 31,688,833 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362230,007,579 - 30,018,474 (-)NCBINCBI36hg18NCBI36
Celera2215,478,064 - 15,489,008 (-)NCBI
Cytogenetic Map22q12.2NCBI
HuRef2214,639,191 - 14,650,132 (-)NCBIHuRef
CHM1_12231,637,394 - 31,648,335 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PIK3IP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605305
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.