Tph2<sup>em3Mcwi</sup> (tryptophan hydroxylase 2; zinc finger nuclease induced mutant 3, Medical College of Wisconsin)

Advanced Search (OLGA)

Gene: Tph2^em3Mcwi (tryptophan hydroxylase 2; zinc finger nuclease induced mutant 3, Medical College of Wisconsin) Rattus norvegicus

Symbol:

Tph2^em3Mcwi

Name:

tryptophan hydroxylase 2; zinc finger nuclease induced mutant 3, Medical College of Wisconsin

RGD ID:

10402820

Description:

This allele was made by ZFN mutagenesis. The resulting mutation is a 11-bp frameshift deletion in exon 7 (del 1027-1037)

Type:

allele of Tph2

Previously known as:

Tph2^[em3Mcwi]; Tph2em3Mcwi

Is Marker For:

Strains: DA-Tph2^em3Mcwi DA-Tph2^em3Mcwi+/+ DA-Tph2^em3Mcwi+/- DA-Tph2^em3Mcwi-/-

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Cytogenetic Map	7		RGD

References

References - curated

#	Reference Title	Reference Citation
1.	Knockout rats via embryo microinjection of zinc-finger nucleases.	Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2.	PhysGen Knockouts	PhysGen Knockout strains

Genomics

Allelic Variants

Name	Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Assembly
Tph2em3Mcwi-var1	chr7	58112644	58112654	GGGGTGTAGAG	-	deletion	Rnor_6.0

Related Rat Strains

The following Strains have been annotated to Tph2^em3Mcwi

DA-Tph2^em3Mcwi+/+ DA-Tph2^em3Mcwi+/- DA-Tph2^em3Mcwi-/- DA-Tph2^em3Mcwi

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_173839	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Additional Information

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message