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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70373
Species: Homo sapiens
RGD Object: Gene
Symbol: BAX
Name: BCL2 associated X, apoptosis regulator
Acc ID: CHEBI:5132
Term: flutamide
Definition: A (trifluoromethyl)benzene that has formula C11H11F3N2O3.
Chemical ID: MESH:D005485
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BAXincreases expressionISOBax (Mus musculus)6480464CTDFlutamide results in increased expression of BAX mRNAPMID:17702527
BAXincreases expressionISOBax (Rattus norvegicus)6480464CTDFlutamide results in increased expression of BAX mRNA; Flutamide results in increased expression of BAX proteinPMID:20850791
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