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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1614055
Species: Mus musculus
RGD Object: Gene
Symbol: Cxcl3
Name: C-X-C motif chemokine ligand 3
Acc ID: CHEBI:16469
Term: 17beta-estradiol
Definition: The 17beta-isomer of estradiol.
Chemical ID: MESH:D004958
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cxcl3multiple interactionsEXP 6480464CTDEstradiol inhibits the reaction [Halothane results in increased expression of CXCL1 mRNA]; fulvestrant inhibits the reaction [Estradiol inhibits the reaction [Halothane results in increased expression of CXCL1 mRNA]]PMID:21501669
Cxcl3increases expressionISOCXCL1 (Homo sapiens)6480464CTDEstradiol results in increased expression of CXCL1 mRNAPMID:25878060
Cxcl3multiple interactionsISOCxcl3 (Rattus norvegicus)6480464CTD[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CXCL3 mRNAPMID:32741896
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