GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NQO1 | multiple interactions | EXP | | 6480464 | CTD | Melatonin inhibits the reaction [cyfluthrin results in decreased activity of NQO1 protein]; Melatonin inhibits the reaction [cyfluthrin results in increased expression of NQO1 mRNA] | PMID:31330490 | NQO1 | increases expression | ISO | Nqo1 (Mus musculus) | 6480464 | CTD | Melatonin results in increased expression of NQO1 protein | PMID:25288107 | NQO1 | increases expression | ISO | Nqo1 (Rattus norvegicus) | 6480464 | CTD | Melatonin results in increased expression of NQO1 protein | PMID:20433640 | NQO1 | multiple interactions | ISO | Nqo1 (Mus musculus) | 6480464 | CTD | Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 protein]]; Melatonin affects the reaction [manganese chloride affects the expression of NQO1 protein]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 mRNA]; Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 protein]; Melatonin inhibits the reaction [diisodecyl phthalate inhibits the reaction [Fluorescein-5-isothiocyanate results in increased expression of NQO1 protein]]; Melatonin inhibits the reaction [manganese chloride results in decreased expression of NQO1 protein]; Melatonin inhibits the reaction [Ozone promotes the reaction [Ovalbumin results in decreased expression of NQO1 mRNA]] | PMID:24969583 PMID:25288107 PMID:27871981 PMID:34146326 PMID:37598416 | NQO1 | multiple interactions | ISO | Nqo1 (Rattus norvegicus) | 6480464 | CTD | [Diethylnitrosamine co-treated with oxfendazole co-treated with Melatonin] results in increased expression of NQO1 mRNA; Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of NQO1 protein] | PMID:20033131 PMID:20433640 | |
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