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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735868
Species: Homo sapiens
RGD Object: Gene
Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
Acc ID: CHEBI:75092
Term: morin
Definition: A pentahydroxyflavone that is 7-hydroxyflavonol bearing three additional hydroxy substituents at positions 2' 4' and 5.
Chemical ID: MESH:C008548
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NQO1multiple interactionsISONqo1 (Rattus norvegicus)25823195RGDMorin enhances the reaction [Carbontetrachloride increases expression of Nqo1 mRNA in liver]  
NQO1multiple interactionsISONqo1 (Rattus norvegicus)6480464CTDmorin inhibits the reaction [Acetaminophen results in decreased activity of NQO1 protein]; morin inhibits the reaction [Acetaminophen results in decreased expression of NQO1 protein]PMID:26767949
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