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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734432
Species: Mus musculus
RGD Object: Gene
Symbol: Nfe2l2
Name: nuclear factor, erythroid derived 2, like 2
Acc ID: CHEBI:6030
Term: isoniazide
Definition: A carbohydrazide obtained by formal condensation between pyridine-4-carboxylic acid and hydrazine.
Chemical ID: MESH:D007538
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2increases activityEXP 6480464CTDIsoniazid results in increased activity of NFE2L2 proteinPMID:30203046
Nfe2l2increases expressionEXP 6480464CTDIsoniazid results in increased expression of NFE2L2 mRNAPMID:33771660
Nfe2l2increases expressionISONfe2l2 (Rattus norvegicus)6480464CTDIsoniazid results in increased expression of NFE2L2 mRNAPMID:33121995
Nfe2l2multiple interactionsISONfe2l2 (Rattus norvegicus)6480464CTDchrysin inhibits the reaction [Isoniazid results in increased expression of NFE2L2 mRNA]PMID:33121995
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