GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | BCL2 | decreases expression | EXP | | 6480464 | CTD | Tretinoin results in decreased expression of BCL2; Tretinoin results in decreased expression of BCL2 mRNA; Tretinoin results in decreased expression of BCL2 protein | PMID:10713328 PMID:12431242 PMID:12644474 PMID:14592536 PMID:15254726 PMID:15498508 PMID:15770638 PMID:15894607 PMID:16109544 PMID:16109552 PMID:16196285 PMID:16242776 PMID:16517207 PMID:16572199 PMID:16778211 PMID:16909596 PMID:17077328 PMID:17701358 PMID:17960384 PMID:18922099 PMID:19176369 PMID:33167477 PMID:9342185 | BCL2 | increases expression | EXP | | 6480464 | CTD | Tretinoin results in increased expression of BCL2 mRNA; Tretinoin results in increased expression of BCL2 protein | PMID:10750663 PMID:21934132 PMID:23724009 PMID:34742744 | BCL2 | increases phosphorylation | EXP | | 6480464 | CTD | Tretinoin results in increased phosphorylation of BCL2 protein | PMID:18098270 | BCL2 | multiple interactions | EXP | | 6480464 | CTD | [1,5-dihydroxyisoquinoline co-treated with Tretinoin] results in decreased expression of BCL2 protein; [Calcitriol co-treated with Tretinoin] results in decreased expression of BCL2 protein; [IDH1 protein affects the susceptibility to Tretinoin] which affects the expression of BCL2 protein; [Melatonin co-treated with Tretinoin] results in decreased expression of BCL2 protein; [Tretinoin co-treated with Arsenic Trioxide] results in decreased expression of BCL2 mRNA; [Tretinoin co-treated with IFNG protein] results in decreased expression of BCL2 protein; [Tretinoin co-treated with Melatonin] results in decreased expression of BCL2 protein; [Tretinoin co-treated with Paclitaxel] results in decreased expression of BCL2 protein; [Tretinoin co-treated with Paclitaxel] results in increased phosphorylation of BCL2 protein; [Tretinoin co-treated with Zoledronic Acid] results in decreased expression of BCL2 protein; [Troglitazone co-treated with Tretinoin] results in decreased expression of BCL2 protein; leptomycin B inhibits the reaction [Tretinoin results in decreased expression of BCL2 protein]; Tretinoin inhibits the reaction [perfluorooctanoic acid results in decreased expression of BCL2 protein] | PMID:10713328 PMID:10965999 PMID:14592536 PMID:15894607 PMID:17701358 PMID:17960384 PMID:18098270 PMID:20349282 PMID:26951332 PMID:32971237 PMID:9649124 PMID:9671760 | BCL2 | decreases expression | ISO | Bcl2 (Mus musculus) | 6480464 | CTD | Tretinoin results in decreased expression of BCL2 protein | PMID:11851873 PMID:12513834 PMID:16712891 PMID:21626648 | BCL2 | decreases expression | ISO | Bcl2 (Rattus norvegicus) | 6480464 | CTD | Tretinoin results in decreased expression of BCL2 protein | PMID:17962954 | | ||||||||||||||||||||||
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