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GENE - TERM ANNOTATION REPORT

RGD ID: 731027
Species: Homo sapiens
RGD Object: Gene
Symbol: BDNF
Name: brain derived neurotrophic factor
Acc ID: DOID:9008023
Term: Memory Disorders
Definition: Disturbances in registering an impression, in the retention of an acquired impression, or in the recall of an impression. Memory impairments are associated with DEMENTIA; CRANIOCEREBRAL TRAUMA; ENCEPHALITIS; ALCOHOLISM (see also ALCOHOL AMNESTIC DISORDER); SCHIZOPHRENIA; and other conditions.
Definition Source(s): MESH:D008569
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
BDNF IEP 401938665RGDassociated with alcohol use disorder; protein:decreased expression:plasma (human) 
BDNF ISOBdnf (Rattus norvegicus)401959600RGDassociated with alcohol use disorder;mRNA,protein:decreased expression:hippocampus 
BDNFtreatmentISOBdnf (Mus musculus)401940181RGD  
BDNFtreatmentISOBdnf (Rattus norvegicus)401960858RGD  
BDNFtreatmentISOBdnf (Rattus norvegicus)401960859RGDassociated with Subarachnoid Hemorrhage 
BDNF IAGP (Homo sapiens)8554872ClinVarClinVar Annotator: match by term: Memory impairment, susceptibility toPMID:12140781 PMID:12161822 PMID:12553913 PMID:12836135 PMID:12888803 PMID:15115760 PMID:15337662 PMID:16152572 PMID:16172806 PMID:16222333 PMID:16344533 PMID:16389585 PMID:20075215 PMID:24033266 PMID:25741868 PMID:28492532
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