GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NOS2 | increases expression | ISO | Nos2 (Rattus norvegicus) | 6480464 | CTD | Monocrotaline results in increased expression of NOS2 mRNA; Monocrotaline results in increased expression of NOS2 protein | PMID:16225752 PMID:22022327 PMID:25460361 PMID:30466619 PMID:31589899 | NOS2 | multiple interactions | ISO | Nos2 (Mus musculus) | 6480464 | CTD | [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of NOS2 mRNA | PMID:21224054 | NOS2 | multiple interactions | ISO | Nos2 (Rattus norvegicus) | 6480464 | CTD | 4-chlorobenzyltetrahydroberberine inhibits the reaction [Monocrotaline results in increased expression of NOS2 mRNA]; liquiritigenin inhibits the reaction [Monocrotaline results in increased expression of NOS2 mRNA]; liquiritin inhibits the reaction [Monocrotaline results in increased expression of NOS2 mRNA]; magnolol inhibits the reaction [Monocrotaline results in increased expression of NOS2 protein]; Quercetin inhibits the reaction [Monocrotaline results in increased expression of NOS2 mRNA]; Simvastatin inhibits the reaction [Monocrotaline results in increased expression of NOS2 mRNA] | PMID:16225752 PMID:22022327 PMID:25460361 PMID:30466619 PMID:31589899 | | ||||||||||||||||||||||
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