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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 727915
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp27a1
Name: cytochrome P450, family 27, subfamily a, polypeptide 1
Acc ID: CHEBI:42977
Term: 25-hydroxycholesterol
Definition: A 25-hydroxy steroid that has formula 402.65294.
Chemical ID: MESH:C007997
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp27a1increases chemical synthesisISOCyp27a1 (Mus musculus)6480464CTDCYP27A1 protein results in increased chemical synthesis of 25-hydroxycholesterolPMID:17890683
Cyp27a1multiple interactionsISOCYP27A1 (Homo sapiens)6480464CTD[CYP27A1 protein results in increased metabolism of Cholesterol] which results in increased chemical synthesis of 25-hydroxycholesterolPMID:8078928
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