GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Rela | multiple interactions | EXP | | 6480464 | CTD | 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [mangiferin inhibits the reaction [Methotrexate results in increased expression of and results in increased phosphorylation of RELA protein]]; mangiferin inhibits the reaction [Excitatory Amino Acid Agonists affects the localization of and results in increased activity of RELA protein]; mangiferin inhibits the reaction [Galactosamine results in increased expression of RELA protein]; mangiferin inhibits the reaction [Methotrexate results in increased expression of and results in increased phosphorylation of RELA protein]; mangiferin inhibits the reaction [Streptozocin results in increased expression of RELA mRNA] | PMID:19201465 PMID:22310181 PMID:36249937 PMID:37044004 | Rela | affects localization | ISO | RELA (Homo sapiens) | 6480464 | CTD | mangiferin affects the localization of RELA protein | PMID:26996543 | Rela | decreases expression | ISO | Rela (Mus musculus) | 6480464 | CTD | mangiferin results in decreased expression of RELA mRNA | PMID:15135318 | Rela | decreases localization | ISO | RELA (Homo sapiens) | 6480464 | CTD | mangiferin results in decreased localization of RELA protein | PMID:21547680 | Rela | multiple interactions | ISO | RELA (Homo sapiens) | 6480464 | CTD | mangiferin inhibits the reaction [TNF protein affects the localization of and results in increased phosphorylation of and results in increased activity of RELA protein] | PMID:15161907 | Rela | multiple interactions | ISO | Rela (Mus musculus) | 6480464 | CTD | mangiferin analog inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 affects the localization of RELA protein]; mangiferin inhibits the reaction [lead nitrate results in increased expression of RELA protein]; mangiferin inhibits the reaction [Scopolamine results in increased phosphorylation of and results in increased activity of RELA protein]; mangiferin inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased activity of RELA protein]; mangiferin inhibits the reaction [TNFSF11 protein results in increased localization of RELA protein] | PMID:19182383 PMID:20683903 PMID:23451106 PMID:27474068 | | ||||||||||||||||||||||
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