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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69165
Species: Homo sapiens
RGD Object: Gene
Symbol: DDIT3
Name: DNA damage inducible transcript 3
Acc ID: CHEBI:18320
Term: 1,4-dithiothreitol
Definition: The threo-diastereomer of 1,4-dimercaptobutane-2,3-diol.
Chemical ID: MESH:D004229
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
DDIT3increases expressionEXP 6480464CTDDithiothreitol results in increased expression of DDIT3 mRNAPMID:17332266 PMID:23123503 PMID:27226639
DDIT3multiple interactionsEXP 6480464CTDindolo(3,2-b)carbazole inhibits the reaction [Dithiothreitol results in increased expression of DDIT3 mRNA]PMID:27226639
DDIT3increases expressionISODdit3 (Rattus norvegicus)6480464CTDDithiothreitol results in increased expression of DDIT3 mRNAPMID:23123503
DDIT3increases expressionISODdit3 (Mus musculus)6480464CTDDithiothreitol results in increased expression of DDIT3 mRNAPMID:27226639
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