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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69139
Species: Homo sapiens
RGD Object: Gene
Symbol: NPPB
Name: natriuretic peptide B
Acc ID: CHEBI:27881
Term: resveratrol
Definition: A stilbenol that is stilbene in which the phenyl groups are substituted at positions 3, 5, and 4' by hydroxy groups.
Chemical ID: MESH:C059514
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
NPPBmultiple interactionsEXP 6480464CTD[Plant Extracts co-treated with Resveratrol] results in decreased expression of NPPB mRNAPMID:23557933
NPPBdecreases expressionISONppb (Mus musculus)6480464CTDresveratrol results in decreased expression of NPPB mRNAPMID:25394648
NPPBdecreases expressionISONppb (Rattus norvegicus)6480464CTDresveratrol results in decreased expression of NPPB mRNA; resveratrol results in decreased expression of NPPB proteinPMID:17499237 PMID:24535859 PMID:26167810
NPPBdecreases secretionISONppb (Rattus norvegicus)6480464CTDresveratrol results in decreased secretion of NPPB proteinPMID:17499237
NPPBmultiple interactionsISONppb (Rattus norvegicus)6480464CTDresveratrol inhibits the reaction [AGT protein results in increased expression of NPPB mRNA]; resveratrol inhibits the reaction [AGT protein results in increased expression of NPPB protein]; resveratrol inhibits the reaction [Oxygen deficiency results in increased expression of NPPB mRNA]; resveratrol inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NPPB mRNA]PMID:18543488 PMID:19969063 PMID:24492474
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