GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tgfb1 | increases expression | EXP | | 6480464 | CTD | Tamoxifen results in increased expression of TGFB1 mRNA | PMID:19453300 | Tgfb1 | multiple interactions | EXP | | 6480464 | CTD | Tamoxifen inhibits the reaction [allyl alcohol results in increased expression of TGFB1 mRNA] | PMID:18564211 | Tgfb1 | decreases expression | ISO | Tgfb1 (Mus musculus) | 6480464 | CTD | Tamoxifen results in decreased expression of TGFB1 mRNA | PMID:19279558 | Tgfb1 | decreases secretion | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | Tamoxifen results in decreased secretion of TGFB1 protein | PMID:8653321 | Tgfb1 | increases expression | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | [Tamoxifen results in increased expression of TGFB1 protein] which results in increased expression of FASLG mRNA; [Tamoxifen results in increased expression of TGFB1 protein] which results in increased expression of GZMB mRNA; [Tamoxifen results in increased expression of TGFB1 protein] which results in increased expression of PRF1 mRNA; Tamoxifen results in increased expression of TGFB1 protein | PMID:20145137 | Tgfb1 | increases secretion | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | Tamoxifen results in increased secretion of TGFB1 protein | PMID:17098229 | Tgfb1 | multiple interactions | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | [Tretinoin co-treated with Tamoxifen] results in increased secretion of TGFB1 protein; TGFB1 protein promotes the reaction [Tamoxifen results in increased expression of FOXP3 mRNA] | PMID:17098229 PMID:20145137 | |
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