GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tgfb1 | multiple interactions | EXP | | 6480464 | CTD | [Losartan co-treated with Vitamin D] inhibits the reaction [Amiodarone results in increased expression of TGFB1 protein]; Vitamin D inhibits the reaction [Amiodarone results in increased expression of TGFB1 protein] | PMID:34590760 | Tgfb1 | multiple interactions | ISO | TGFB1 (Homo sapiens) | 6480464 | CTD | [TGFB1 protein co-treated with Vitamin D] results in increased expression of VDR mRNA; HRC protein inhibits the reaction [Vitamin D inhibits the reaction [TGFB1 protein results in increased expression of SMAD3 protein]]; HRC protein inhibits the reaction [Vitamin D inhibits the reaction [TGFB1 protein results in increased expression of TGFB1 protein]]; HRC protein inhibits the reaction [Vitamin D inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]]; Vitamin D inhibits the reaction [TGFB1 protein results in increased expression of and results in increased phosphorylation of SMAD3 protein]; Vitamin D inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA]; Vitamin D inhibits the reaction [TGFB1 protein results in increased expression of HRC mRNA]; Vitamin D inhibits the reaction [TGFB1 protein results in increased expression of HRC protein]; Vitamin D inhibits the reaction [TGFB1 protein results in increased expression of TGFB1 protein] | PMID:33309619 | Tgfb1 | multiple interactions | ISO | Tgfb1 (Mus musculus) | 6480464 | CTD | Vitamin D inhibits the reaction [Particulate Matter results in increased expression of TGFB1 protein]; Vitamin D inhibits the reaction [Silicon Dioxide results in increased expression of TGFB1 protein]; Vitamin D inhibits the reaction [Tretinoin results in decreased susceptibility to TGFB1 protein] | PMID:21152098 PMID:30698894 | | ||||||||||||||||||||||
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