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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69026
Species: Homo sapiens
RGD Object: Gene
Symbol: PRKCD
Name: protein kinase C delta
Acc ID: CHEBI:16236
Term: ethanol
Definition: A primary alcohol that is ethane in which one of the hydrogens is substituted by a hydroxy group.
Chemical ID: MESH:D000431
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PRKCDincreases phosphorylationEXP 6480464CTDEthanol results in increased phosphorylation of PRKCD proteinPMID:18182400
PRKCDmultiple interactionsEXP 6480464CTDsodium arsenite promotes the reaction [Ethanol results in increased phosphorylation of PRKCD protein]PMID:18182400
PRKCDaffects expressionISOPrkcd (Mus musculus)6480464CTDEthanol affects the expression of PRKCD mRNAPMID:30319688
PRKCDincreases expressionISOPrkcd (Rattus norvegicus)6480464CTDEthanol results in increased expression of PRKCD mRNAPMID:20655511
PRKCDincreases expressionISOPrkcd (Mus musculus)6480464CTDEthanol results in increased expression of PRKCD mRNAPMID:21955143
PRKCDmultiple interactionsISOPrkcd (Rattus norvegicus)6480464CTDEthanol inhibits the reaction [Streptozocin results in increased expression of PRKCD protein]; N-methyl-N-(6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-ylmethyl)aminomethylcarboxylic acid inhibits the reaction [Ethanol results in increased expression of PRKCD mRNA]PMID:12198386 PMID:20655511
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