GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Mtor | decreases expression | ISO | Mtor (Rattus norvegicus) | 6480464 | CTD | lead acetate results in decreased expression of MTOR mRNA; lead acetate results in decreased expression of MTOR protein | PMID:30980912 PMID:36807407 | Mtor | decreases phosphorylation | ISO | Mtor (Rattus norvegicus) | 6480464 | CTD | lead acetate results in decreased phosphorylation of MTOR protein | PMID:22811615 PMID:32879255 | Mtor | increases phosphorylation | ISO | MTOR (Homo sapiens) | 6480464 | CTD | lead acetate results in increased phosphorylation of MTOR protein | PMID:34842334 | Mtor | multiple interactions | ISO | Mtor (Rattus norvegicus) | 6480464 | CTD | [lead acetate results in increased abundance of Lead] which results in decreased expression of MTOR mRNA; [lead acetate results in increased abundance of Lead] which results in decreased expression of MTOR protein; naringenin inhibits the reaction [lead acetate results in decreased expression of MTOR protein] | PMID:36652739 PMID:36807407 | Mtor | multiple interactions | ISO | MTOR (Homo sapiens) | 6480464 | CTD | SRT1720 inhibits the reaction [lead acetate results in increased phosphorylation of MTOR protein] | PMID:34842334 | | ||||||||||||||||||||||
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