GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnfrsf1a | decreases expression | EXP | | 6480464 | CTD | Acetaminophen results in decreased expression of TNFRSF1A mRNA | PMID:33387578 | Tnfrsf1a | increases expression | EXP | | 6480464 | CTD | Acetaminophen results in increased expression of TNFRSF1A mRNA | PMID:32479839 | Tnfrsf1a | affects expression | ISO | Tnfrsf1a (Mus musculus) | 6480464 | CTD | Acetaminophen affects the expression of TNFRSF1A mRNA | PMID:17562736 | Tnfrsf1a | affects response to substance | ISO | Tnfrsf1a (Mus musculus) | 6480464 | CTD | TNFRSF1A protein affects the susceptibility to Acetaminophen | PMID:22461450 | Tnfrsf1a | decreases expression | ISO | TNFRSF1A (Homo sapiens) | 6480464 | CTD | Acetaminophen results in decreased expression of TNFRSF1A mRNA | PMID:21420995 PMID:29067470 | Tnfrsf1a | decreases response to substance | ISO | Tnfrsf1a (Mus musculus) | 6480464 | CTD | TNFRSF1A protein results in decreased susceptibility to Acetaminophen | PMID:14550746 | Tnfrsf1a | increases expression | ISO | Tnfrsf1a (Mus musculus) | 6480464 | CTD | Acetaminophen results in increased expression of TNFRSF1A mRNA; Acetaminophen results in increased expression of TNFRSF1A protein | PMID:12540782 PMID:14557383 PMID:22461450 PMID:22575169 | Tnfrsf1a | increases response to substance | ISO | Tnfrsf1a (Mus musculus) | 6480464 | CTD | TNFRSF1A protein results in increased susceptibility to Acetaminophen | PMID:14557383 | Tnfrsf1a | multiple interactions | ISO | Tnfrsf1a (Mus musculus) | 6480464 | CTD | LGALS3 protein affects the reaction [Acetaminophen results in increased expression of TNFRSF1A mRNA]; MST1R protein affects the reaction [Acetaminophen results in increased expression of TNFRSF1A protein]; O(2)-vinyl-1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate inhibits the reaction [Acetaminophen results in increased expression of TNFRSF1A mRNA]; TNFRSF1A protein affects the reaction [Acetaminophen results in increased expression of CCN2 mRNA]; TNFRSF1A protein affects the reaction [Acetaminophen results in increased expression of LGALS3 mRNA]; TNFRSF1A protein affects the reaction [Acetaminophen results in increased expression of MMP9 mRNA]; TNFRSF1A protein affects the reaction [Acetaminophen results in increased expression of SLC3A2 mRNA]; TNFRSF1A protein affects the reaction [Acetaminophen results in increased expression of TNF mRNA]; TNFRSF1A protein affects the reaction [Acetaminophen results in increased expression of TNF protein]; TNFRSF1A protein affects the reaction [pimagedine inhibits the reaction [NOS2 protein results in increased susceptibility to Acetaminophen]]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of CCL2 mRNA]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of CCL2 protein]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of CCL3 mRNA]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of CCL3 protein]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of CXCL2 mRNA]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of CXCL2 protein]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of ICAM1 mRNA]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of IFNG mRNA]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of IL10 mRNA]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of IL1A mRNA]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of IL1B mRNA]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of IL6 mRNA]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of NOS2 mRNA]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of SELE mRNA]; TNFRSF1A protein promotes the reaction [Acetaminophen results in increased expression of VCAM1 mRNA]; TNFRSF1A protein results in decreased susceptibility to [Acetaminophen results in increased expression of NOS2 protein] | PMID:12540782 PMID:14550746 PMID:14557383 PMID:22461450 PMID:22575169 | | ||||||||||||||||||||||
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