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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621170
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Anxa2
Name: annexin A2
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Anxa2decreases expressionISOANXA2 (Homo sapiens)6480464CTDTretinoin results in decreased expression of ANXA2 mRNA; Tretinoin results in decreased expression of ANXA2 proteinPMID:12165291 PMID:15498508 PMID:16140955 PMID:16197459 PMID:19642359 PMID:23724009 PMID:28886987 PMID:33167477
Anxa2multiple interactionsISOAnxa2 (Mus musculus)6480464CTD[bisphenol F co-treated with Tretinoin] results in decreased expression of ANXA2 mRNAPMID:30951980
Anxa2multiple interactionsISOANXA2 (Homo sapiens)6480464CTDTretinoin affects the localization of and results in decreased expression of ANXA2 proteinPMID:12165291
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