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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62081
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hes1
Name: hes family bHLH transcription factor 1
Acc ID: CHEBI:28748
Term: doxorubicin
Definition: An anthracycline antibiotic that has formula C27H29NO11.
Chemical ID: MESH:D004317
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hes1affects expressionEXP 6480464CTDDoxorubicin affects the expression of HES1 mRNAPMID:31307187
Hes1increases expressionISOHES1 (Homo sapiens)6480464CTDDoxorubicin results in increased expression of HES1 mRNAPMID:29968951
Hes1increases expressionISOHes1 (Mus musculus)6480464CTDDoxorubicin results in increased expression of HES1 mRNAPMID:28318631
Hes1multiple interactionsISOHES1 (Homo sapiens)6480464CTDMIR760 mRNA inhibits the reaction [Doxorubicin results in increased expression of HES1 mRNA]PMID:29968951
Hes1multiple interactionsISOHes1 (Mus musculus)6480464CTDNiclosamide inhibits the reaction [Doxorubicin results in increased expression of HES1 mRNA]PMID:28318631
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