GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nfe2l2 | multiple interactions | EXP | | 6480464 | CTD | [Atorvastatin co-treated with dapagliflozin] inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of NFE2L2 protein]; [Fructose co-treated with Dietary Fats] results in increased expression of NFE2L2 protein; Atorvastatin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of NFE2L2 protein]; dapagliflozin inhibits the reaction [[Fructose co-treated with Dietary Fats] results in increased expression of NFE2L2 protein] | PMID:32259528 | Nfe2l2 | increases expression | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | Fructose results in increased expression of NFE2L2 protein | PMID:27531227 | Nfe2l2 | multiple interactions | ISO | NFE2L2 (Homo sapiens) | 6480464 | CTD | [Fructose co-treated with Palmitic Acid] results in decreased expression of NFE2L2 protein; Fenofibrate inhibits the reaction [[Fructose co-treated with Palmitic Acid] results in decreased expression of NFE2L2 protein] | PMID:32730863 | Nfe2l2 | multiple interactions | ISO | Nfe2l2 (Mus musculus) | 6480464 | CTD | Fructose promotes the reaction [PPARD gene mutant form results in increased phosphorylation of NFE2L2 protein]; Plant Preparations inhibits the reaction [Fructose results in increased expression of NFE2L2 protein] | PMID:27531227 PMID:29289645 | | ||||||||||||||||||||||
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