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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62001
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Muc5ac
Name: mucin 5AC, oligomeric mucus/gel-forming
Acc ID: CHEBI:15367
Term: all-trans-retinoic acid
Definition: A retinoic acid in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014212
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Muc5acincreases expressionISOMUC5AC (Homo sapiens)6480464CTDTretinoin results in increased expression of MUC5AC mRNAPMID:17034753
Muc5acmultiple interactionsISOMUC5AC (Homo sapiens)6480464CTD[Chir 99021 co-treated with BMP4 protein co-treated with FGF10 protein co-treated with FGF7 protein co-treated with Tretinoin] results in increased expression of MUC5AC mRNA; Tretinoin inhibits the reaction [sodium arsenite results in decreased expression of MUC5AC mRNA]PMID:32201329 PMID:35267148
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