GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tp53 | multiple interactions | ISO | Trp53 (Mus musculus) | 6480464 | CTD | sirtinol inhibits the reaction [resveratrol inhibits the reaction [Doxorubicin results in increased expression of TRP53 protein]] | PMID:25665036 | Tp53 | multiple interactions | ISO | TP53 (Homo sapiens) | 6480464 | CTD | [sirtinol results in decreased activity of SIRT1 protein] promotes the reaction [Hydrogen Peroxide results in increased acetylation of TP53 protein]; sirtinol promotes the reaction [arsenic disulfide results in increased expression of and results in increased phosphorylation of TP53 protein]; sirtinol promotes the reaction [cudraflavone B results in increased expression of TP53 protein] | PMID:18298901 PMID:18681908 PMID:23881456 | | ||||||||||||||||||||||
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