GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | increases expression | ISO | Tnf (Mus musculus) | 6480464 | CTD | Floxacillin results in increased expression of TNF mRNA | PMID:24652713 | Tnf | increases secretion | ISO | TNF (Homo sapiens) | 6480464 | CTD | Floxacillin results in increased secretion of TNF protein | PMID:28444390 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | [Floxacillin co-treated with [TNF protein co-treated with IL6 protein co-treated with IL1B protein]] results in increased activity of CASP3 protein; [Floxacillin co-treated with TNF protein] results in increased activity of CASP3 protein; [TNF protein co-treated with IL6 protein co-treated with IL1B protein] promotes the reaction [Floxacillin results in increased activity of CASP3 protein] | PMID:30876886 | | ||||||||||||||||||||||
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