GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Tnf | multiple interactions | EXP | | 6480464 | CTD | Emodin inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TNF protein]; Emodin inhibits the reaction [Oxaliplatin results in increased expression of TNF protein]; Emodin inhibits the reaction [TNF protein results in increased expression of GFAP protein]; Emodin inhibits the reaction [TNF protein results in increased expression of IL1B protein]; Emodin inhibits the reaction [TNF protein results in increased expression of PTGS2 protein]; Emodin inhibits the reaction [TNF protein results in increased expression of RELA protein] | PMID:18590720 PMID:36184831 | Tnf | multiple interactions | ISO | Tnf (Mus musculus) | 6480464 | CTD | Emodin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF mRNA]; Emodin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of TNF protein]; Emodin inhibits the reaction [Tobacco Smoke Pollution results in increased secretion of TNF protein] | PMID:26139382 PMID:37023836 | Tnf | multiple interactions | ISO | TNF (Homo sapiens) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Emodin inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein]]; Emodin inhibits the reaction [TNF protein results in increased expression of GSTP1 mRNA]; Emodin inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein]; Emodin promotes the reaction [2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein]] | PMID:14534369 PMID:15313406 | | ||||||||||||||||||||||
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