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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3728
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Snap25
Name: synaptosome associated protein 25
Acc ID: CHEBI:34905
Term: paraquat
Definition: An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Chemical ID: MESH:D010269
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Snap25increases expressionISOSNAP25 (Homo sapiens)6480464CTDParaquat results in increased expression of SNAP25 mRNA; Paraquat results in increased expression of SNAP25 proteinPMID:35430322
Snap25increases expressionISOSnap25 (Mus musculus)6480464CTDParaquat results in increased expression of SNAP25 mRNA; Paraquat results in increased expression of SNAP25 proteinPMID:35430322
Snap25multiple interactionsISOSnap25 (Mus musculus)6480464CTDSYT1 protein affects the reaction [Paraquat results in increased expression of SNAP25 mRNA]; SYT1 protein affects the reaction [Paraquat results in increased expression of SNAP25 protein]PMID:35430322
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