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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:paraquat
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Accession:CHEBI:34905 term browser browse the term
Definition:An organic cation that consists of 4,4'-bipyridine bearing two N-methyl substituents loctated at the 1- and 1'-positions.
Synonyms:exact_synonym: 1,1'-dimethyl-[4,4'-bipyridin]-1,1'-diium
 related_synonym: 1,1'-Dimethyl-4,4'-bipyridinium;   1,1'-dimethyl-4,4'-bipyridyldiylium;   Formula=C12H14N2;   InChI=1S/C12H14N2/c1-13-7-3-11(4-8-13)12-5-9-14(2)10-6-12/h3-10H,1-2H3/q+2;   InChIKey=INFDPOAKFNIJBF-UHFFFAOYSA-N;   N,N'-dimethyl-4,4'-bipyridinium;   N,N'-dimethyl-4,4'-bipyridinium dication;   SMILES=C[n+]1ccc(cc1)-c1cc[n+](C)cc1;   dimethyl viologen;   methyl viologen ion(2+);   paraquat dication;   paraquat ion
 xref: Beilstein:3590305;   CAS:4685-14-7;   Gmelin:51125;   KEGG:C14701
 xref_mesh: MESH:D010269
 xref: PMID:11349957;   PMID:18620719;   PMID:20377249;   PMID:20582739;   PMID:21236547;   PMID:21300143;   PMID:21318114;   PMID:21429624;   PMID:21493003;   PMID:21598522;   PMID:21616728;   PMID:21619794;   PMID:21619822;   PMID:21750730;   PMID:21777615;   PMID:21787677;   PMID:21802509;   PPDB:505;   Reaxys:3590305

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paraquat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aaas aladin WD repeat nucleoporin affects response to substance ISO AAAS protein affects the susceptibility to Paraquat CTD PMID:23315990 NCBI chr 7:143,937,198...143,956,668
Ensembl chr 7:143,937,199...143,956,668 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 increases expression
decreases expression
multiple interactions		 ISO Paraquat results in increased expression of ABCA1 mRNA
Paraquat results in decreased expression of ABCA1 protein
TO-901317 inhibits the reaction [Paraquat results in decreased expression of ABCA1 protein]		 CTD PMID:27788593 PMID:28480221 NCBI chr 5:69,857,717...69,983,042
Ensembl chr 5:69,857,771...69,983,015 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
affects expression		 ISO
EXP		 [Doxorubicin results in increased expression of ABCB1 protein] which results in decreased susceptibility to Paraquat; ABCB1 protein affects the reaction [Doxorubicin results in decreased susceptibility to Paraquat]; ABCB1 protein results in increased export of and results in decreased susceptibility to Paraquat; valspodar inhibits the reaction [ABCB1 protein results in increased export of Paraquat]
Paraquat affects the expression of ABCB1A mRNA
[ABCB1A gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of HAVCR1 mRNA; [ABCB1A gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of LCN2 mRNA; [ABCB1A gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of NQO1 mRNA; ABCB1A protein results in increased export of and results in decreased susceptibility to Paraquat		 CTD PMID:16854511 PMID:23220037 PMID:25015657 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression
multiple interactions		 EXP
ISO		 Paraquat results in increased expression of ABCB1B mRNA
[ABCB1B gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of HAVCR1 mRNA; [ABCB1B gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of LCN2 mRNA; [ABCB1B gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of NQO1 mRNA; ABCB1B protein results in increased export of and results in decreased susceptibility to Paraquat		 CTD PMID:11557130 PMID:15177642 PMID:25015657 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases expression		 ISO ABCC1 protein promotes the reaction [cycloartenyl ferulate results in increased transport of and results in decreased abundance of Paraquat]; cycloartenyl ferulate inhibits the reaction [Paraquat results in decreased expression of ABCC1 protein] CTD PMID:26358524 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 affects expression EXP Paraquat affects the expression of ABCC4 mRNA CTD PMID:16854511 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592 		JBrowse link
G Abcc9 ATP binding cassette subfamily C member 9 affects expression EXP Paraquat affects the expression of ABCC9 mRNA CTD PMID:16854511 NCBI chr 4:176,806,098...176,928,540
Ensembl chr 4:176,805,431...176,922,424 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Paraquat results in increased expression of ABCG2 mRNA CTD PMID:12595580 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621 		JBrowse link
G Abhd17b abhydrolase domain containing 17B, depalmitoylase increases expression ISO Paraquat results in increased expression of ABHD17B mRNA CTD PMID:21371552 NCBI chr 1:239,266,140...239,301,133
Ensembl chr 1:239,266,921...239,301,176 		JBrowse link
G Abl1 ABL proto-oncogene 1, non-receptor tyrosine kinase increases expression ISO Paraquat results in increased expression of ABL1 mRNA CTD PMID:18836921 NCBI chr 3:10,041,820...10,145,076
Ensembl chr 3:10,041,826...10,144,388 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases phosphorylation
multiple interactions		 EXP
ISO		 Paraquat results in increased phosphorylation of ACACA protein
PRKAA1 protein affects the reaction [Paraquat results in increased phosphorylation of ACACA protein]		 CTD PMID:27324791 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910 		JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain affects expression EXP Paraquat affects the expression of ACADL mRNA CTD PMID:18198484 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888 		JBrowse link
G Acads acyl-CoA dehydrogenase short chain multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ACADS mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ACADS mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ACADS mRNA] CTD PMID:23963992 NCBI chr12:47,254,503...47,263,747
Ensembl chr12:47,254,484...47,263,747 		JBrowse link
G Acan aggrecan decreases expression ISO Paraquat results in decreased expression of ACAN mRNA CTD PMID:26108578 NCBI chr 1:140,762,758...140,824,441
Ensembl chr 1:140,762,758...140,824,441 		JBrowse link
G Ace angiotensin I converting enzyme multiple interactions
decreases expression
decreases activity
affects expression		 ISO
EXP		 pimagedine inhibits the reaction [Paraquat results in decreased activity of ACE protein]
Paraquat results in decreased expression of ACE mRNA
Paraquat affects the expression of ACE protein
Curcumin inhibits the reaction [Paraquat affects the expression of ACE protein]; Unithiol inhibits the reaction [Paraquat results in decreased expression of ACE mRNA]		 CTD PMID:10666014 PMID:12161173 PMID:16182431 PMID:20465954 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 multiple interactions
decreases expression		 EXP Unithiol inhibits the reaction [Paraquat results in decreased expression of ACE2 mRNA] CTD PMID:20465954 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016 		JBrowse link
G Ache acetylcholinesterase multiple interactions
decreases activity
increases expression		 ISO
EXP		 [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of ACHE mRNA
Paraquat results in decreased activity of ACHE protein
Paraquat results in increased expression of ACHE mRNA		 CTD PMID:23017109 PMID:28916328 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753 		JBrowse link
G Aco1 aconitase 1 increases activity
decreases expression
decreases activity		 ISO
EXP		 Paraquat results in increased activity of ACO1 protein
Paraquat results in decreased expression of ACO1 protein
Paraquat results in decreased activity of ACO1 protein		 CTD PMID:11520895 PMID:15664434 PMID:17324120 PMID:28542246 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218 		JBrowse link
G Aco2 aconitase 2 decreases activity
multiple interactions
affects response to substance		 ISO
EXP		 Paraquat results in decreased activity of ACO2 protein
[GCLM gene mutant form results in increased susceptibility to Paraquat] which results in decreased activity of ACO2 protein; [Paraquat co-treated with Maneb] results in decreased expression of ACO2 mRNA
ACO2 protein affects the susceptibility to Paraquat
ACO2 protein affects the reaction [Paraquat results in increased abundance of Hydrogen Peroxide]; ACO2 protein affects the reaction [Paraquat results in increased abundance of Iron]
SNCA protein inhibits the reaction [Paraquat results in decreased activity of ACO2 protein]		 CTD PMID:11520895 PMID:15234109 PMID:18386188 PMID:21517855 PMID:23704229 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635 		JBrowse link
G Acot7 acyl-CoA thioesterase 7 affects expression EXP Paraquat affects the expression of BACH mRNA CTD PMID:15206577 NCBI chr 5:169,357,582...169,450,215
Ensembl chr 5:169,357,517...169,450,219 		JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 affects expression
decreases expression		 EXP Paraquat affects the expression of ACSL1 mRNA
Paraquat results in decreased expression of ACSL1 mRNA		 CTD PMID:15206577 PMID:18198484 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression		 ISO
EXP		 CMA1 protein promotes the reaction [Paraquat results in increased expression of ACTA2 protein]; HIF1A protein affects the reaction [Paraquat results in increased expression of ACTA2 protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [Rosiglitazone inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]]; 2-chloro-5-nitrobenzanilide inhibits the reaction [Rosiglitazone inhibits the reaction [Paraquat results in increased expression of ACTA2 protein]]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of ACTA2 protein]; HIF1A protein affects the reaction [Paraquat results in increased expression of ACTA2 protein]; Rosiglitazone inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; Rosiglitazone inhibits the reaction [Paraquat results in increased expression of ACTA2 protein]; TRAM 34 inhibits the reaction [Paraquat results in increased expression of ACTA2 protein]
Paraquat results in increased expression of ACTA2 mRNA; Paraquat results in increased expression of ACTA2 protein
ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; enterotoxin C, staphylococcal analog inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; Fingolimod Hydrochloride inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; Fingolimod Hydrochloride inhibits the reaction [Paraquat results in increased expression of ACTA2 protein]; pirfenidone inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of ACTA2 protein]; thymoquinone inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]		 CTD PMID:17215068 PMID:19969051 PMID:24893116 PMID:25304964 PMID:25873302 PMID:25945502 PMID:26099602 PMID:26758514 PMID:26781174 PMID:26824344 PMID:27375216 PMID:29273418 PMID:30036685 PMID:30317802 PMID:30403199 PMID:30797787 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394 		JBrowse link
G Actb actin, beta increases expression ISO Paraquat results in increased expression of ACTB mRNA CTD PMID:20883675 NCBI chr12:13,715,843...13,718,813
Ensembl chr12:13,715,843...13,718,841 		JBrowse link
G Acvr1 activin A receptor type 1 affects expression
decreases expression		 EXP Paraquat affects the expression of ACVR1 mRNA
Paraquat results in decreased expression of ACVR1 mRNA		 CTD PMID:15206577 PMID:18198484 NCBI chr 3:44,432,476...44,539,680
Ensembl chr 3:44,432,471...44,522,930 		JBrowse link
G Acvr2a activin A receptor type 2A decreases expression
affects expression		 EXP Paraquat results in decreased expression of ACVR2A mRNA
Paraquat affects the expression of ACVR2A mRNA		 CTD PMID:16854511 PMID:18198484 NCBI chr 3:32,947,901...33,034,598
Ensembl chr 3:32,947,378...33,034,282 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 increases expression ISO Paraquat results in increased expression of ADAM17 mRNA; Paraquat results in increased expression of ADAM17 protein CTD PMID:29495171 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280 		JBrowse link
G Adam22 ADAM metallopeptidase domain 22 multiple interactions
increases expression		 ISO [Paraquat co-treated with Maneb] affects the expression of ADAM22 mRNA
Paraquat results in increased expression of ADAM22 mRNA		 CTD PMID:22563483 NCBI chr 4:22,864,485...23,002,969
Ensembl chr 4:22,859,622...22,996,645 		JBrowse link
G Adcy5 adenylate cyclase 5 increases expression EXP Paraquat results in increased expression of ADCY5 mRNA CTD PMID:17077588 NCBI chr11:68,695,839...68,842,452
Ensembl chr11:68,695,839...68,842,320 		JBrowse link
G Adcy6 adenylate cyclase 6 increases expression EXP Paraquat results in increased expression of ADCY6 mRNA CTD PMID:18198484 NCBI chr 7:140,270,678...140,291,722
Ensembl chr 7:140,270,692...140,291,620 		JBrowse link
G Adcyap1 adenylate cyclase activating polypeptide 1 decreases response to substance ISO ADCYAP1 protein results in decreased susceptibility to Paraquat CTD PMID:23500093 NCBI chr 9:121,705,897...121,725,736
Ensembl chr 9:121,706,979...121,725,716 		JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ADGRB1 mRNA CTD PMID:23017109 NCBI chr 7:115,766,484...115,828,514 JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ADGRG1 mRNA CTD PMID:18386188 NCBI chr19:10,423,534...10,460,674
Ensembl chr19:10,423,501...10,460,674 		JBrowse link
G Adgrl1 adhesion G protein-coupled receptor L1 affects expression EXP Paraquat affects the expression of ADGRL1 mRNA CTD PMID:15493455 NCBI chr19:25,029,037...25,069,146
Ensembl chr19:25,029,037...25,069,142 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]; ADIPOQ protein promotes the reaction [Paraquat results in increased expression of ADIPOR1 mRNA]; ADIPOQ protein promotes the reaction [Paraquat results in increased expression of ADIPOR1 protein]; ADIPOR1 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]]
ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of MMP9 protein]; ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of TIMP1 protein]		 CTD PMID:25945502 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488 		JBrowse link
G Adipor1 adiponectin receptor 1 multiple interactions
increases expression		 ISO ADIPOQ protein promotes the reaction [Paraquat results in increased expression of ADIPOR1 mRNA]; ADIPOQ protein promotes the reaction [Paraquat results in increased expression of ADIPOR1 protein]; ADIPOR1 protein inhibits the reaction [Paraquat results in increased expression of ADIPOR2 mRNA]; ADIPOR1 protein inhibits the reaction [Paraquat results in increased expression of ADIPOR2 protein]; ADIPOR1 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]]
Paraquat results in increased expression of ADIPOR1 mRNA; Paraquat results in increased expression of ADIPOR1 protein		 CTD PMID:25945502 NCBI chr13:51,240,470...51,260,233
Ensembl chr13:51,240,911...51,260,228 		JBrowse link
G Adipor2 adiponectin receptor 2 multiple interactions
increases expression		 ISO ADIPOR1 protein inhibits the reaction [Paraquat results in increased expression of ADIPOR2 mRNA]; ADIPOR1 protein inhibits the reaction [Paraquat results in increased expression of ADIPOR2 protein]
Paraquat results in increased expression of ADIPOR2 mRNA; Paraquat results in increased expression of ADIPOR2 protein		 CTD PMID:25945502 NCBI chr 4:151,412,135...151,480,108
Ensembl chr 4:151,414,684...151,428,894 		JBrowse link
G Adora1 adenosine A1 receptor multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of ADORA1 mRNA CTD PMID:23017109 NCBI chr13:51,042,111...51,076,913
Ensembl chr13:51,042,248...51,076,852 		JBrowse link
G Adora2a adenosine A2a receptor affects expression
increases expression		 EXP Paraquat affects the expression of ADORA2A mRNA
Paraquat results in increased expression of ADORA2A mRNA		 CTD PMID:16854511 PMID:17077588 PMID:18198484 NCBI chr20:14,265,251...14,282,873
Ensembl chr20:14,265,252...14,282,873 		JBrowse link
G Adprh ADP-ribosylarginine hydrolase increases expression ISO Paraquat results in increased expression of ADPRH mRNA CTD PMID:21371552 NCBI chr11:64,861,772...64,868,112
Ensembl chr11:64,861,768...64,868,108 		JBrowse link
G Adra1a adrenoceptor alpha 1A decreases expression EXP Paraquat results in decreased expression of ADRA1A mRNA CTD PMID:17077588 NCBI chr15:43,296,997...43,398,314
Ensembl chr15:43,298,794...43,392,451 		JBrowse link
G Adra1d adrenoceptor alpha 1D decreases expression EXP Paraquat results in decreased expression of ADRA1D mRNA CTD PMID:17077588 NCBI chr 3:124,129,558...124,145,566
Ensembl chr 3:124,129,558...124,145,566 		JBrowse link
G Ager advanced glycosylation end product-specific receptor decreases secretion
multiple interactions
increases expression		 EXP Paraquat results in decreased secretion of AGER protein modified form
Febuxostat inhibits the reaction [Paraquat results in decreased secretion of AGER protein modified form]; Febuxostat inhibits the reaction [Paraquat results in increased expression of AGER mRNA]		 CTD PMID:30726711 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079 		JBrowse link
G Ago3 argonaute RISC catalytic component 3 multiple interactions
increases expression		 ISO [Paraquat co-treated with Maneb] affects the expression of AGO3 mRNA
Paraquat results in increased expression of AGO3 mRNA		 CTD PMID:22563483 NCBI chr 5:144,355,792...144,436,509
Ensembl chr 5:144,364,269...144,436,509 		JBrowse link
G Agt angiotensinogen multiple interactions
increases expression
increases secretion		 ISO AGT protein modified form promotes the reaction [Paraquat results in increased expression of TGFB1 protein]; CMA1 protein promotes the reaction [Paraquat results in increased expression of AGT protein modified form]
Paraquat results in increased expression of AGT mRNA; Paraquat results in increased expression of AGT protein modified form
Paraquat results in increased secretion of AGT protein		 CTD PMID:19969051 PMID:20035857 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a increases expression ISO Paraquat results in increased expression of AGTR1 mRNA; Paraquat results in increased expression of AGTR1 protein CTD PMID:20035857 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 decreases expression ISO Paraquat results in decreased expression of AGTR2 mRNA CTD PMID:20035857 NCBI chr  X:119,389,480...119,393,845
Ensembl chr  X:119,390,013...119,393,842 		JBrowse link
G Ahnak AHNAK nucleoprotein increases expression ISO Paraquat results in increased expression of AHNAK mRNA CTD PMID:22563483 NCBI chr 1:225,184,883...225,429,638
Ensembl chr 1:225,184,939...225,215,015 		JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression ISO Paraquat results in decreased expression of AHR protein CTD PMID:26196221 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464 		JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of AIF1 protein; [MTHFR gene polymorphism affects the susceptibility to Paraquat] which results in increased expression of AIF1 protein; [Paraquat co-treated with Maneb] results in increased expression of AIF1 protein; acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of AIF1 protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of AIF1 protein] CTD PMID:28202386 PMID:30726997 PMID:32375810 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO AIFM1 protein inhibits the reaction [Paraquat results in decreased reduction of Glutathione]; AIFM1 protein promotes the reaction [Paraquat results in decreased reduction of Adenine Nucleotides] CTD PMID:15316071 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087 		JBrowse link
G Ak1 adenylate kinase 1 increases expression ISO Paraquat results in increased expression of AK1 mRNA CTD PMID:21371552 NCBI chr 3:11,652,143...11,659,135 JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of AKR1B3 mRNA CTD PMID:18386188 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of AKR1C3 mRNA CTD PMID:28012437 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression
affects phosphorylation
multiple interactions		 ISO Paraquat results in decreased expression of AKT1 mRNA
Paraquat affects the phosphorylation of AKT1 protein
ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of AKT1 protein]
[Maneb co-treated with Paraquat] results in decreased expression of AKT1 mRNA; AKT1 protein affects the reaction [Paraquat results in decreased expression of BCL2 protein]; AKT1 protein affects the reaction [Paraquat results in increased activity of CASP3 protein]; AKT1 protein affects the reaction [Paraquat results in increased expression of BAX protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of AKT1 protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of AKT1 mRNA]; Paraquat results in increased expression of and results in increased phosphorylation of AKT1 protein; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of AKT1 mRNA]		 CTD PMID:16797015 PMID:23898955 PMID:23963992 PMID:28115273 PMID:28428137 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 multiple interactions
increases response to substance		 ISO AKT2 protein affects the reaction [Paraquat results in decreased expression of PPARGC1A protein]; AKT2 protein affects the reaction [Paraquat results in increased expression of NFE2L2 protein]
AKT2 protein results in increased susceptibility to Paraquat		 CTD PMID:28115273 NCBI chr 1:84,400,939...84,451,223
Ensembl chr 1:84,411,726...84,450,162 		JBrowse link
G Alad aminolevulinate dehydratase decreases activity EXP Paraquat results in decreased activity of ALAD protein CTD PMID:12180188 NCBI chr 5:78,368,867...78,379,206
Ensembl chr 5:78,368,867...78,379,346 		JBrowse link
G Alas1 5'-aminolevulinate synthase 1 multiple interactions
increases activity		 EXP alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of ALAS1 protein] CTD PMID:12180188 NCBI chr 8:114,927,704...114,941,038
Ensembl chr 8:114,927,722...114,940,177 		JBrowse link
G Alas2 5'-aminolevulinate synthase 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of ALAS2 mRNA CTD PMID:22563483 NCBI chr  X:23,167,576...23,187,356
Ensembl chr  X:23,167,696...23,187,341 		JBrowse link
G Alb albumin decreases expression EXP Paraquat results in decreased expression of ALB protein CTD PMID:17481832 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO Paraquat results in increased expression of ALDH1A1 mRNA CTD PMID:12595580 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 affects expression EXP Paraquat affects the expression of ALDH1A2 mRNA CTD PMID:15206577 NCBI chr 8:77,640,234...77,719,488
Ensembl chr 8:77,640,222...77,719,489 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases expression EXP Paraquat results in decreased expression of ALDH2 mRNA CTD PMID:18198484 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752 		JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ALDH5A1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ALDH5A1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ALDH5A1 mRNA] CTD PMID:23963992 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ALDOC mRNA CTD PMID:18386188 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126 		JBrowse link
G Alkbh8 alkB homolog 8, tRNA methyltransferase increases expression ISO Paraquat results in increased expression of ALKBH8 mRNA CTD PMID:21371552 NCBI chr 6:18,877,885...18,952,773
Ensembl chr 6:18,877,907...18,949,393 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type increases expression ISO Paraquat results in increased expression of ALOX12B mRNA CTD PMID:28012437 NCBI chr10:55,744,646...55,756,524
Ensembl chr10:55,744,588...55,756,566 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase multiple interactions
decreases expression		 ISO APOD protein affects the reaction [Paraquat results in decreased expression of ALOX15 mRNA]; Paraquat affects the reaction [APOD protein affects the expression of ALOX15 mRNA] CTD PMID:21688324 NCBI chr10:56,953,692...56,962,145
Ensembl chr10:56,953,691...56,962,161 		JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B increases expression ISO Paraquat results in increased expression of ALOX8 mRNA CTD PMID:28012437 NCBI chr10:55,773,748...55,783,489
Ensembl chr10:55,774,006...55,783,489 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase increases expression ISO Paraquat results in increased expression of ALOX5 mRNA CTD PMID:28012437 NCBI chr 4:148,398,004...148,446,308
Ensembl chr 4:148,398,892...148,446,303 		JBrowse link
G Amh anti-Mullerian hormone decreases expression EXP Paraquat results in decreased expression of AMH mRNA CTD PMID:31128353 NCBI chr 7:11,775,155...11,777,503
Ensembl chr 7:11,775,155...11,777,503 		JBrowse link
G Amn amnion associated transmembrane protein multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of AMN mRNA CTD PMID:22563483 NCBI chr 6:135,724,455...135,731,896
Ensembl chr 6:135,724,455...135,731,896 		JBrowse link
G Amph amphiphysin decreases expression EXP Paraquat results in decreased expression of AMPH mRNA CTD PMID:18198484 NCBI chr17:48,304,324...48,562,838
Ensembl chr17:48,304,322...48,562,905 		JBrowse link
G Anxa1 annexin A1 increases expression EXP Paraquat results in increased expression of ANXA1 protein CTD PMID:24521700 NCBI chr 1:237,893,983...237,910,002
Ensembl chr 1:237,893,966...237,910,012 		JBrowse link
G Anxa2 annexin A2 increases expression EXP Paraquat results in increased expression of ANXA2 protein CTD PMID:24521700 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594 		JBrowse link
G Anxa5 annexin A5 increases expression ISO Paraquat results in increased expression of ANXA5 mRNA CTD PMID:20883675 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130 		JBrowse link
G Ap3b2 adaptor related protein complex 3 subunit beta 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of AP3B2 mRNA CTD PMID:18386188 NCBI chr 1:143,284,041...143,315,846
Ensembl chr 1:143,283,996...143,315,633 		JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of AP3D1 mRNA CTD PMID:18386188 NCBI chr 7:11,838,639...11,873,992
Ensembl chr 7:11,838,639...11,873,984 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 decreases expression
affects splicing
increases expression		 ISO Paraquat results in decreased expression of APAF1 mRNA
Paraquat affects the splicing of APAF1 exon
Paraquat affects the splicing of APAF1 mRNA
Paraquat results in increased expression of APAF1 mRNA alternative form		 CTD PMID:17064354 PMID:23613995 PMID:27111068 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192 		JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of APBB1 mRNA CTD PMID:23017109 NCBI chr 1:170,387,625...170,411,263
Ensembl chr 1:170,387,609...170,404,056 		JBrowse link
G Apeh acylaminoacyl-peptide hydrolase decreases response to substance ISO APEH protein results in decreased susceptibility to Paraquat CTD PMID:12727222 NCBI chr 8:116,862,664...116,871,776
Ensembl chr 8:116,862,625...116,872,215 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 increases response to substance
affects response to substance		 ISO APEX1 gene mutant form results in increased susceptibility to Paraquat
APEX1 gene SNP affects the susceptibility to Paraquat		 CTD PMID:11454706 PMID:28460087 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082 		JBrowse link
G Apln apelin decreases expression ISO Paraquat results in decreased expression of APLN mRNA CTD PMID:32870474 NCBI chr  X:134,856,719...134,866,210
Ensembl chr  X:134,856,726...134,866,210 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO Paraquat affects the expression of and results in increased degradation of APOA1 mRNA CTD PMID:9169468 NCBI chr 8:50,525,091...50,526,875
Ensembl chr 8:50,525,091...50,526,875 		JBrowse link
G Apod apolipoprotein D multiple interactions
increases expression
decreases response to substance
affects response to substance		 ISO Paraquat results in increased uptake of and affects the localization of APOD protein; pyrazolanthrone inhibits the reaction [Paraquat results in increased expression of APOD mRNA]; pyrazolanthrone inhibits the reaction [Paraquat results in increased expression of APOD protein]
APOD protein results in decreased susceptibility to Paraquat
APOD protein affects the susceptibility to Paraquat
[Paraquat co-treated with APOD gene mutant form] results in increased expression of NOS2 mRNA; APOD protein affects the reaction [Paraquat results in decreased expression of ALOX15 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of AQR mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of EPX mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of GAB1 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of GPX2 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of IDH1 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of LPO mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of NOS2 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of NOX4 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of NOXO1 mRNA]; APOD protein affects the reaction [Paraquat results in decreased expression of PTGS1 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of DUOX1 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of GDNF mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of GFAP protein]; APOD protein affects the reaction [Paraquat results in increased expression of GPX3 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of IL19 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of MPP4 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of PTGS2 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of SOD2 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of SOD3 mRNA]; APOD protein affects the reaction [Paraquat results in increased expression of SRXN1 mRNA]; APOD protein inhibits the reaction [Paraquat results in decreased activity of CTSB protein]; Paraquat affects the reaction [APOD protein affects the expression of ALOX15 mRNA]; Paraquat affects the reaction [APOD protein affects the expression of HMOX1 protein]; Paraquat affects the reaction [APOD protein affects the expression of SOD2 protein]
Paraquat results in increased expression of APOD mRNA; Paraquat results in increased expression of APOD protein		 CTD PMID:18419796 PMID:18458334 PMID:21688324 PMID:28182653 NCBI chr11:72,705,204...72,726,263
Ensembl chr11:72,705,129...72,726,301 		JBrowse link
G App amyloid beta precursor protein increases response to substance
multiple interactions
increases expression		 ISO
EXP		 APP protein results in increased susceptibility to Paraquat
Estradiol inhibits the reaction [Paraquat results in increased expression of APP protein alternative form]; Estradiol inhibits the reaction [Paraquat results in increased expression of APP protein]
Paraquat results in increased expression of APP protein; Paraquat results in increased expression of APP protein alternative form
Carnitine promotes the reaction [Paraquat deficiency inhibits the reaction [Paraquat promotes the reaction [APP protein binds to APP protein]]]; Curcumin inhibits the reaction [Paraquat results in increased expression of APP mRNA]; Curcumin inhibits the reaction [Paraquat results in increased expression of APP protein]; Paraquat deficiency inhibits the reaction [Paraquat promotes the reaction [APP protein binds to APP protein]]; Paraquat promotes the reaction [APP protein binds to APP protein]
Paraquat results in increased expression of APP mRNA; Paraquat results in increased expression of APP protein		 CTD PMID:23827522 PMID:27793699 PMID:31715309 PMID:33290254 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Aprt adenine phosphoribosyl transferase decreases expression ISO Paraquat results in decreased expression of APRT mRNA CTD PMID:21371552 NCBI chr19:55,387,288...55,389,256
Ensembl chr19:55,387,288...55,389,256 		JBrowse link
G Aqp1 aquaporin 1 increases expression ISO Paraquat results in increased expression of AQP1 mRNA CTD PMID:12595580 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360 		JBrowse link
G Aqr aquarius intron-binding spliceosomal factor multiple interactions
decreases expression		 ISO APOD protein affects the reaction [Paraquat results in decreased expression of AQR mRNA] CTD PMID:21688324 NCBI chr 3:105,570,399...105,640,431
Ensembl chr 3:105,570,292...105,640,463 		JBrowse link
G Arf1 ADP-ribosylation factor 1 affects expression EXP Paraquat affects the expression of ARF1 mRNA CTD PMID:15206577 NCBI chr10:45,562,700...45,579,214
Ensembl chr10:45,563,547...45,579,029 		JBrowse link
G Arf3 ADP-ribosylation factor 3 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ARF3 mRNA CTD PMID:18386188 NCBI chr 7:140,412,463...140,438,751
Ensembl chr 7:140,398,199...140,437,467 		JBrowse link
G Arf5 ADP-ribosylation factor 5 increases expression EXP Paraquat results in increased expression of ARF5 mRNA CTD PMID:17077588 NCBI chr 4:55,715,744...55,718,670
Ensembl chr 4:55,715,744...55,718,670 		JBrowse link
G Arg1 arginase 1 increases expression
multiple interactions
decreases expression		 EXP
ISO		 Paraquat results in increased expression of ARG1 mRNA
[Paraquat co-treated with Maneb] results in increased expression of ARG1 mRNA
Paraquat results in decreased expression of ARG1 protein
Paraquat results in decreased expression of ARG1 mRNA		 CTD PMID:20388547 PMID:24521700 PMID:28467894 PMID:29568078 PMID:31299241 PMID:32375810 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863 		JBrowse link
G Arg2 arginase 2 increases expression EXP Paraquat results in increased expression of ARG2 mRNA CTD PMID:16854511 PMID:20388547 NCBI chr 6:102,311,097...102,338,406
Ensembl chr 6:102,311,116...102,338,520 		JBrowse link
G Arl2 ADP-ribosylation factor like GTPase 2 decreases expression ISO Paraquat results in decreased expression of ARL2 protein CTD PMID:23807224 NCBI chr 1:221,504,150...221,516,191
Ensembl chr 1:221,504,170...221,516,110 		JBrowse link
G Arl6ip5 ADP-ribosylation factor like GTPase 6 interacting protein 5 affects response to substance
increases expression
multiple interactions		 ISO ARL6IP5 protein affects the susceptibility to Paraquat
Paraquat results in increased expression of ARL6IP5
Paraquat results in increased expression of ARL6IP5 protein
ARL6IP5 protein affects the reaction [Paraquat affects the expression of NFE2L2 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the expression of TH protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of AKT1 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of MAPK1 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of MAPK3 protein]
ARL6IP5 protein affects the reaction [Paraquat affects the expression of NFE2L2 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of AKT1 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of MAPK1 protein]; ARL6IP5 protein affects the reaction [Paraquat affects the phosphorylation of MAPK3 protein]		 CTD PMID:28428137 NCBI chr 4:129,574,363...129,598,240
Ensembl chr 4:129,574,264...129,598,915 		JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of ARNT2 mRNA CTD PMID:23017109 NCBI chr 1:146,399,217...146,556,437
Ensembl chr 1:146,399,217...146,556,171 		JBrowse link
G Art3 ADP-ribosyltransferase 3 increases expression ISO Paraquat results in increased expression of ART3 mRNA CTD PMID:12595580 NCBI chr14:17,143,037...17,225,389
Ensembl chr14:17,143,040...17,225,389 		JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of ASCL1 mRNA CTD PMID:23017109 NCBI chr 7:28,038,662...28,040,504
Ensembl chr 7:28,038,662...28,040,510 		JBrowse link
G Asic1 acid sensing ion channel subunit 1 affects expression
increases expression		 EXP Paraquat affects the expression of ASIC1 mRNA
Paraquat results in increased expression of ASIC1 mRNA		 CTD PMID:15206577 PMID:17077588 PMID:18198484 NCBI chr 7:141,324,714...141,354,937
Ensembl chr 7:141,326,321...141,354,937 		JBrowse link
G Asic3 acid sensing ion channel subunit 3 increases expression EXP Paraquat results in increased expression of ACCN3 mRNA CTD PMID:18198484 NCBI chr 4:7,287,868...7,293,295
Ensembl chr 4:7,288,855...7,292,901 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Paraquat results in increased expression of ATF3 mRNA CTD PMID:12595580 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632 		JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Paraquat results in increased expression of ATF4 mRNA CTD PMID:21371552 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772 		JBrowse link
G Atf6 activating transcription factor 6 increases expression
increases cleavage
multiple interactions		 EXP
ISO		 Paraquat results in increased expression of ATF6 protein
Paraquat results in increased cleavage of ATF6 protein
Paraquat results in increased expression of ATF6 protein modified form
Minocycline inhibits the reaction [Paraquat results in increased expression of ATF6 protein]		 CTD PMID:22245251 PMID:28986289 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443 		JBrowse link
G Atg12 autophagy related 12 increases expression
multiple interactions		 ISO Paraquat results in increased expression of ATG12 protein
Paraquat results in increased expression of ATG12 mRNA
ATG5 protein affects the reaction [Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]]; Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]
[Paraquat co-treated with Chlorpyrifos] results in increased expression of ATG12 protein; Maneb promotes the reaction [Paraquat results in increased expression of ATG12 protein]; Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]		 CTD PMID:22292029 PMID:22982048 PMID:26884967 PMID:27220436 NCBI chr18:40,721,799...40,732,143
Ensembl chr18:40,721,800...40,732,126 		JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase increases expression ISO Paraquat results in increased expression of ATG4B mRNA CTD PMID:21371552 NCBI chr 9:100,888,457...100,920,123
Ensembl chr 9:100,888,501...100,918,637 		JBrowse link
G Atg5 autophagy related 5 affects response to substance
increases expression
multiple interactions		 ISO
EXP		 ATG5 protein affects the susceptibility to Paraquat
Paraquat results in increased expression of ATG5 mRNA
[ATG5 protein affects the susceptibility to Paraquat] which affects the abundance of Lipofuscin; ATG5 protein affects the reaction [Paraquat results in increased expression of LAMP1 protein]; Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]; TLR4 protein affects the reaction [Paraquat results in increased expression of ATG5 protein]
Paraquat results in increased expression of ATG5 mRNA; Paraquat results in increased expression of ATG5 protein
[ATG5 protein affects the susceptibility to Paraquat] which affects the abundance of Lipofuscin; ATG5 protein affects the reaction [Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]]; ATG5 protein affects the reaction [Paraquat results in increased expression of LAMP1 protein]; ATG5 protein affects the reaction [Paraquat results in increased expression of MAP1LC3A protein]; ATG5 protein promotes the reaction [Paraquat results in increased cleavage of and results in increased activity of CASP3 protein]; Paraquat results in increased expression of [ATG5 protein binds to ATG12 protein]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of ATG5 mRNA]		 CTD PMID:22982048 PMID:23997112 PMID:27220436 PMID:27246695 PMID:27324791 PMID:30171970 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140 		JBrowse link
G Atg7 autophagy related 7 increases expression
affects response to substance
multiple interactions		 ISO Paraquat results in increased expression of ATG7 protein
ATG7 protein affects the susceptibility to Paraquat
Paraquat results in increased expression of ATG7 mRNA
[ATG7 protein affects the susceptibility to Paraquat] which affects the expression of AKR1C3 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of ATM mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BACH1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BARD1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BLM mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BRCA1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BUB1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BUB1B mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNA2 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNB1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNB2 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNE1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNE2 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDC20 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDC25C mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDK1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDK2 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDKN1A mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CHEK1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of FANCA mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of FANCB mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of FANCD2 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of KIF11 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of KIF14 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of KIF23 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of NBN mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of PLK1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of PLK4 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of PRC1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of SMC1A mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of STAT1 mRNA; [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of TRP53 protein; ATG7 protein affects the reaction [Paraquat results in decreased expression of LMNB1 protein]; ATG7 protein affects the reaction [Paraquat results in increased expression of CDKN1A protein]; ATG7 protein affects the reaction [Paraquat results in increased expression of H2AX protein]; ATG7 protein affects the reaction [Paraquat results in increased expression of TRP53 mRNA]; Paraquat affects the reaction [ATG7 protein affects the expression of CDK1 mRNA]; Paraquat affects the reaction [ATG7 protein affects the expression of CDK1 protein]; Paraquat affects the reaction [ATG7 protein affects the expression of LMNB1 mRNA]; TLR4 protein affects the reaction [Paraquat results in increased expression of ATG7 protein]		 CTD PMID:27220436 PMID:27246695 PMID:28012437 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124 		JBrowse link
G Atm ATM serine/threonine kinase increases expression
multiple interactions		 ISO Paraquat results in increased expression of ATM mRNA
[ATG7 protein affects the susceptibility to Paraquat] which affects the expression of ATM mRNA		 CTD PMID:20883675 PMID:28012437 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045 		JBrowse link
G Atp13a2 ATPase cation transporting 13A2 multiple interactions
increases response to substance		 ISO [ATP13A2 protein results in increased susceptibility to Paraquat] which results in increased abundance of Reactive Oxygen Species CTD PMID:22265822 NCBI chr 5:159,512,208...159,531,631
Ensembl chr 5:159,512,285...159,531,637 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 increases expression EXP Paraquat results in increased expression of ATP1A1 mRNA CTD PMID:16854511 NCBI chr 2:204,003,742...204,032,023
Ensembl chr 2:204,003,742...204,032,023 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 affects expression
increases expression
decreases expression		 EXP
ISO		 Paraquat affects the expression of ATP1A2 mRNA
Paraquat results in increased expression of ATP1A2 mRNA
Paraquat results in decreased expression of ATP1A2 mRNA		 CTD PMID:16854511 PMID:17077588 PMID:18198484 PMID:21371552 NCBI chr13:90,651,682...90,676,629
Ensembl chr13:90,651,686...90,676,629 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 affects expression
increases expression		 EXP Paraquat affects the expression of ATP1B1 mRNA
Paraquat results in increased expression of ATP1B1 mRNA		 CTD PMID:16555045 PMID:16854511 NCBI chr13:82,737,161...82,757,681
Ensembl chr13:82,737,159...82,758,004 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions
affects expression
increases expression		 ISO
EXP		 IGF1 gene mutant form inhibits the reaction [Paraquat results in increased expression of ATP2A2 protein]
Paraquat affects the expression of ATP2A2 mRNA		 CTD PMID:16854511 PMID:17979500 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326 		JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 decreases expression EXP Paraquat results in decreased expression of ATP2B2 mRNA CTD PMID:18198484 NCBI chr 4:145,704,779...145,948,997
Ensembl chr 4:145,703,046...146,016,325 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ATP5A1 protein; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ATP5A1 protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ATP5A1 protein] CTD PMID:23562983 NCBI chr18:74,156,553...74,164,490
Ensembl chr18:74,156,553...74,164,495 		JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ATP5G1 mRNA CTD PMID:18386188 NCBI chr10:83,895,941...83,898,640
Ensembl chr10:83,895,947...83,898,527 		JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 multiple interactions ISO ATP6V0A1 protein affects the reaction [Paraquat results in increased expression of MAP1LC3A protein] CTD PMID:22982048 NCBI chr10:88,914,264...88,967,736
Ensembl chr10:88,914,276...88,967,748 		JBrowse link
G Atp6v0b ATPase H+ transporting V0 subunit B multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ATP6V0B mRNA CTD PMID:18386188 NCBI chr 5:136,718,352...136,719,868
Ensembl chr 5:136,718,352...136,721,379 		JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ATP6V0C mRNA CTD PMID:18386188 NCBI chr10:13,537,031...13,543,407
Ensembl chr10:13,537,033...13,542,077 		JBrowse link
G Atp6v0e2 ATPase, H+ transporting V0 subunit e2 increases expression ISO Paraquat results in increased expression of ATP6V0E2 mRNA CTD PMID:21371552 NCBI chr 4:78,168,117...78,171,265
Ensembl chr 4:78,168,117...78,171,265 		JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ATP6V1C1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ATP6V1C1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ATP6V1C1 mRNA] CTD PMID:23963992 NCBI chr 7:77,678,853...77,716,658
Ensembl chr 7:77,678,968...77,716,408 		JBrowse link
G Atp7a ATPase copper transporting alpha multiple interactions
increases response to substance		 ISO ATP7A protein promotes the reaction [Paraquat results in increased chemical synthesis of Hydrogen Peroxide]
ATP7A protein results in increased susceptibility to Paraquat		 CTD PMID:29058724 NCBI chr  X:77,076,085...77,193,644
Ensembl chr  X:77,076,106...77,193,644 		JBrowse link
G Atxn1 ataxin 1 affects expression EXP Paraquat affects the expression of ATXN1 mRNA CTD PMID:15206577 NCBI chr17:19,160,986...19,533,814
Ensembl chr17:19,249,952...19,533,814 		JBrowse link
G Atxn2 ataxin 2 affects splicing ISO Paraquat affects the splicing of ATXN2 exon CTD PMID:27111068 NCBI chr12:40,264,601...40,335,637
Ensembl chr12:40,266,662...40,332,612 		JBrowse link
G Aurka aurora kinase A affects expression ISO Paraquat affects the expression of AURKA mRNA CTD PMID:26345256 NCBI chr 3:170,364,177...170,380,278
Ensembl chr 3:170,364,181...170,378,210 		JBrowse link
G Avp arginine vasopressin increases expression ISO Paraquat results in increased expression of AVP mRNA; Paraquat results in increased expression of AVP protein CTD PMID:30744883 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460 		JBrowse link
G Avpr1b arginine vasopressin receptor 1B decreases expression EXP Paraquat results in decreased expression of AVPR1B mRNA CTD PMID:17077588 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831 		JBrowse link
G Avpr2 arginine vasopressin receptor 2 decreases expression EXP Paraquat results in decreased expression of AVPR2 mRNA CTD PMID:18198484 NCBI chr  X:156,889,006...156,892,707
Ensembl chr  X:156,889,410...156,891,213 		JBrowse link
G Axin1 axin 1 decreases expression
multiple interactions		 ISO Paraquat results in decreased expression of AXIN1 mRNA; Paraquat results in decreased expression of AXIN1 protein
WNT1 protein inhibits the reaction [Paraquat results in decreased expression of AXIN1 mRNA]		 CTD PMID:30171970
G Axin2 axin 2 decreases expression ISO Paraquat results in decreased expression of AXIN2 mRNA CTD PMID:27788593 NCBI chr10:97,212,483...97,238,824
Ensembl chr10:97,212,432...97,239,642 		JBrowse link
G Bach1 BTB domain and CNC homolog 1 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BACH1 mRNA CTD PMID:28012437 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
increases expression
decreases expression		 ISO
EXP		 [Paraquat co-treated with Maneb] results in increased phosphorylation of BAD protein
TLR4 gene mutant form inhibits the reaction [Paraquat results in increased expression of BAD protein]
Paraquat results in decreased expression of BAD mRNA
Paraquat results in increased expression of BAD mRNA		 CTD PMID:15824117 PMID:17935786 PMID:18836921 PMID:27442881 NCBI chr 1:222,198,516...222,207,459
Ensembl chr 1:222,198,534...222,207,453 		JBrowse link
G Bag1 BAG cochaperone 1 increases expression ISO Paraquat results in increased expression of BAG1 mRNA CTD PMID:18836921 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002 		JBrowse link
G Bag4 BAG cochaperone 4 increases expression ISO Paraquat results in increased expression of BAG4 mRNA CTD PMID:18836921 NCBI chr16:71,057,709...71,075,874
Ensembl chr16:71,058,022...71,075,320 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression
multiple interactions
affects response to substance
decreases expression		 ISO
EXP		 Paraquat results in increased expression of BAK1 mRNA; Paraquat results in increased expression of BAK1 protein
[Paraquat co-treated with Maneb] results in increased expression of BAK1 protein; LGK974 inhibits the reaction [Paraquat results in increased expression of BAK1 protein]; Maneb inhibits the reaction [BAK1 protein affects the susceptibility to Paraquat]; Paraquat inhibits the reaction [BAK1 protein affects the susceptibility to Maneb]
[Maneb co-treated with Paraquat] results in increased expression of BAK1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAK1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAK1 mRNA]
Paraquat results in decreased expression of BAK1 mRNA
NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of BAK1 mRNA]; Paraquat promotes the reaction [BAX protein binds to BAK1 protein]		 CTD PMID:18056701 PMID:18266926 PMID:18836921 PMID:22230393 PMID:22678742 PMID:23963992 PMID:25947082 PMID:30205152 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260 		JBrowse link
G Bard1 BRCA1 associated RING domain 1 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BARD1 mRNA CTD PMID:28012437 NCBI chr 9:78,297,723...78,368,777
Ensembl chr 9:78,294,834...78,369,031 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
affects expression
increases expression
decreases expression		 ISO
EXP		 [Maneb co-treated with Paraquat] results in increased expression of BAX mRNA; [Paraquat co-treated with Maneb] results in increased expression of BAX protein; AKT1 protein affects the reaction [Paraquat results in increased expression of BAX protein]; GPX1 protein affects the reaction [Paraquat affects the expression of BAX mRNA]; Lithium Chloride inhibits the reaction [Paraquat results in increased expression of BAX protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of BAX protein]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAX mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of BAX protein]; Silymarin inhibits the reaction [Paraquat results in increased expression of BAX protein]; TO-901317 inhibits the reaction [Paraquat results in increased expression of BAX protein]
Paraquat results in increased expression of BAX mRNA; Paraquat results in increased expression of BAX protein
[Paraquat co-treated with Maneb] results in increased expression of BAX protein; BAX protein affects the susceptibility to [Paraquat co-treated with Maneb]; Curcumin inhibits the reaction [Paraquat results in increased expression of BAX protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Paraquat results in increased expression of BAX protein]; salvin inhibits the reaction [Paraquat results in increased expression of BAX protein]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of BAX protein]
Paraquat results in decreased expression of BAX mRNA
[Paraquat co-treated with Decitabine] results in increased expression of BAX protein; Anthocyanins inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of BAX protein]; Docosahexaenoic Acids inhibits the reaction [Paraquat results in increased expression of BAX protein]; fasudil inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; Paraquat promotes the reaction [BAX protein binds to BAK1 protein]; Paraquat results in increased expression of and affects the localization of BAX protein		 CTD PMID:12654481 PMID:12714668 PMID:15206577 PMID:15824117 PMID:18253895 PMID:18266926 PMID:18836921 PMID:20964710 PMID:22678742 PMID:22796470 PMID:23963992 PMID:25947082 PMID:26468117 PMID:26686574 PMID:26887261 PMID:27220436 PMID:27442881 PMID:27793699 PMID:28115273 PMID:28480221 PMID:29054699 PMID:30088170 PMID:30171970 PMID:30185695 PMID:30403199 PMID:31128353 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Paraquat results in increased expression of BBC3 protein CTD PMID:18266926 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bche butyrylcholinesterase decreases activity ISO Paraquat results in decreased activity of BCHE protein CTD PMID:17364237 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395 		JBrowse link
G Bckdhb branched chain keto acid dehydrogenase E1 subunit beta increases expression ISO Paraquat results in increased expression of BCKDHB mRNA CTD PMID:21371552 NCBI chr 8:91,464,229...91,656,134
Ensembl chr 8:91,464,229...91,656,134 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor decreases expression ISO Paraquat results in decreased expression of BCL10 mRNA CTD PMID:18836921 NCBI chr 2:251,805,392...251,814,957
Ensembl chr 2:251,805,392...251,814,957 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
decreases response to substance
increases expression		 ISO
EXP		 [Maneb co-treated with Paraquat] results in decreased expression of BCL2 mRNA; AKT1 protein affects the reaction [Paraquat results in decreased expression of BCL2 protein]; GPX1 protein affects the reaction [Paraquat affects the expression of BCL2 mRNA]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of BCL2 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of BCL2 mRNA]; Silymarin inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; TO-901317 inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]
Paraquat results in decreased expression of BCL2 mRNA; Paraquat results in decreased expression of BCL2 protein
Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; salvin inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]
BCL2 protein results in decreased susceptibility to Paraquat
Paraquat results in increased expression of BCL2 mRNA
[Paraquat co-treated with Decitabine] results in decreased expression of BCL2 protein; Anthocyanins inhibits the reaction [Paraquat results in decreased expression of BCL2 mRNA]; Anthocyanins inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; Docosahexaenoic Acids inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; fasudil inhibits the reaction [Paraquat results in decreased expression of BCL2 mRNA]; NFE2L2 mutant form inhibits the reaction [Paraquat results in decreased expression of BCL2 mRNA]		 CTD PMID:12654481 PMID:12714668 PMID:15475374 PMID:18836921 PMID:22230393 PMID:22678742 PMID:22796470 PMID:23963992 PMID:26468117 PMID:26686574 PMID:26887261 PMID:27220436 PMID:28115273 PMID:28480221 PMID:29054699 PMID:30088170 PMID:30171970 PMID:30185695 PMID:30403199 PMID:30698896 PMID:31128353 PMID:31400064 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374 		JBrowse link
G Bcl2a1 BCL2-related protein A1 decreases expression
multiple interactions
increases expression		 ISO Paraquat results in decreased expression of BCL2A1 mRNA
[Paraquat co-treated with Maneb] results in increased expression of BCL2A1 protein
Paraquat results in increased expression of BCL2A1 mRNA; Paraquat results in increased expression of BCL2A1 protein		 CTD PMID:18056701 PMID:18266926 PMID:18836921 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
decreases expression
affects expression
decreases response to substance		 ISO
EXP		 [Paraquat co-treated with Maneb] results in decreased expression of BCL2L1 protein
Paraquat results in increased expression of BCL2L1 mRNA; Paraquat results in increased expression of BCL2L1 protein
Paraquat results in decreased expression of BCL2L1 mRNA
Paraquat affects the expression of BCL2L1 mRNA
BCL2L1 gene mutant form results in decreased susceptibility to Paraquat
GPX1 protein affects the reaction [Paraquat results in increased expression of BCL2L1 protein]		 CTD PMID:10970895 PMID:12595580 PMID:12654481 PMID:15824117 PMID:16797015 PMID:16854511 PMID:18056701 PMID:18836921 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810 		JBrowse link
G Bcl2l10 BCL2 like 10 decreases expression ISO Paraquat results in decreased expression of BCL2L10 mRNA CTD PMID:18836921 NCBI chr 8:82,288,705...82,294,750
Ensembl chr 8:82,288,705...82,294,744 		JBrowse link
G Bcl2l11 BCL2 like 11 decreases expression
multiple interactions
increases expression		 ISO Paraquat results in decreased expression of BCL2L11 mRNA
[Paraquat co-treated with Maneb] results in increased expression of BCL2L11 protein
Paraquat results in increased expression of BCL2L11 protein
Paraquat results in increased expression of BCL2L11 mRNA
FOXO3 mutant form inhibits the reaction [Paraquat results in increased expression of BCL2L11 mRNA]		 CTD PMID:18266926 PMID:18836921 PMID:23620592 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192 		JBrowse link
G Bcl2l2 Bcl2-like 2 multiple interactions ISO GPX1 protein affects the reaction [Paraquat affects the expression of BCL2L2 mRNA] CTD PMID:12654481 NCBI chr15:33,543,774...33,549,165
Ensembl chr15:33,544,312...33,549,164 		JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression ISO Paraquat results in decreased expression of BCLAF1 mRNA CTD PMID:18836921 NCBI chr 1:15,799,753...15,828,838
Ensembl chr 1:15,782,477...15,860,624 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
decreases expression
increases expression		 ISO
EXP		 [Maneb co-treated with Paraquat] results in decreased expression of BDNF mRNA; LRRK2 protein mutant form promotes the reaction [Paraquat results in decreased expression of BDNF protein]
Paraquat results in increased expression of BDNF mRNA
[Paraquat co-treated with Maneb] results in decreased expression of BDNF mRNA; [Paraquat co-treated with Maneb] results in decreased expression of BDNF protein		 CTD PMID:23017109 PMID:27460631 PMID:29454966 PMID:31174552 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210 		JBrowse link
G Becn1 beclin 1 multiple interactions
decreases expression
increases expression		 ISO [Paraquat co-treated with MAP3K5 protein] results in increased expression of BECN1 protein; salubrinal promotes the reaction [[Paraquat co-treated with MAP3K5 protein] results in increased expression of BECN1 protein]; Sirolimus inhibits the reaction [Paraquat results in decreased expression of BECN1 protein]; WNT1 protein inhibits the reaction [Paraquat results in increased expression of BECN1 mRNA]
[Paraquat co-treated with Chlorpyrifos] results in increased expression of BECN1 protein; [Paraquat co-treated with Maneb] results in increased expression of BECN1 protein
Paraquat results in increased expression of BECN1 mRNA; Paraquat results in increased expression of BECN1 protein		 CTD PMID:20929985 PMID:22292029 PMID:25092649 PMID:26884967 PMID:27220436 PMID:30171970 PMID:32306690 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297 		JBrowse link
G Bfar bifunctional apoptosis regulator increases expression ISO Paraquat results in increased expression of BFAR mRNA CTD PMID:18836921 NCBI chr10:1,464,658...1,471,152
NCBI chr10:1,464,783...1,497,653
Ensembl chr10:1,464,765...1,497,653 		JBrowse link
G Bicd1 BICD cargo adaptor 1 increases expression
multiple interactions		 ISO Paraquat results in increased expression of BICD1 mRNA
[Paraquat co-treated with Maneb] affects the expression of BICD1 mRNA		 CTD PMID:22563483 NCBI chr 4:184,018,845...184,167,628
Ensembl chr 4:184,019,087...184,165,540 		JBrowse link
G Bid BH3 interacting domain death agonist decreases expression
multiple interactions
increases expression
increases cleavage		 ISO Paraquat results in decreased expression of BID mRNA
[Maneb co-treated with Paraquat] results in increased expression of BID protein
Paraquat results in increased expression of BID mRNA; Paraquat results in increased expression of BID protein
Paraquat results in increased cleavage of BID protein		 CTD PMID:18056701 PMID:18266926 PMID:18836921 PMID:28414160 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203 		JBrowse link
G Bik BCL2-interacting killer increases expression
multiple interactions		 ISO Paraquat results in increased expression of BIK mRNA
[Paraquat co-treated with Maneb] results in increased expression of BIK protein		 CTD PMID:18266926 PMID:18836921 NCBI chr 7:124,390,924...124,410,449
Ensembl chr 7:124,391,432...124,410,447 		JBrowse link
G Bin1 bridging integrator 1 affects splicing ISO Paraquat affects the splicing of BIN1 mRNA CTD PMID:23613995 NCBI chr18:25,163,575...25,222,139
Ensembl chr18:25,163,561...25,222,135 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO Paraquat results in decreased expression of BIRC2 mRNA CTD PMID:18836921 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO Paraquat results in decreased expression of BIRC3 mRNA CTD PMID:18836921 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression
decreases expression		 ISO
EXP		 Paraquat results in increased expression of BIRC5 mRNA
Paraquat results in decreased expression of BIRC5 mRNA		 CTD PMID:26345256 PMID:26887261 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413 		JBrowse link
G Blm BLM RecQ like helicase multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BLM mRNA CTD PMID:28012437 NCBI chr 1:142,246,773...142,332,616
Ensembl chr 1:142,246,790...142,332,588 		JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP2 mRNA CTD PMID:23017109 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318 		JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions
decreases expression		 ISO
EXP		 [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP4 mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP4 mRNA
Paraquat results in decreased expression of BMP4 mRNA		 CTD PMID:18198484 PMID:23017109 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740 		JBrowse link
G Bnip1 BCL2 interacting protein 1 decreases expression ISO Paraquat results in decreased expression of BNIP1 mRNA CTD PMID:18836921 NCBI chr10:16,677,077...16,689,321
Ensembl chr10:16,677,077...16,689,321 		JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression
affects response to substance
increases expression		 ISO Paraquat results in decreased expression of BNIP3 mRNA
BNIP3 protein affects the susceptibility to Paraquat
Paraquat results in increased expression of BNIP3 protein
Paraquat results in increased expression of BNIP3 mRNA; Paraquat results in increased expression of BNIP3 protein		 CTD PMID:18056701 PMID:18266926 PMID:18836921 PMID:23315990 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Paraquat results in increased expression of BNIP3L mRNA CTD PMID:18836921 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029 		JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor increases expression ISO Paraquat results in increased expression of BOP1 mRNA CTD PMID:21371552 NCBI chr 7:117,514,529...117,538,342
Ensembl chr 7:117,514,533...117,538,342 		JBrowse link
G Brca1 BRCA1, DNA repair associated decreases response to substance
multiple interactions		 ISO BRCA1 protein results in decreased susceptibility to Paraquat
[ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BRCA1 mRNA		 CTD PMID:15520196 PMID:28012437 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681 		JBrowse link
G Brca2 BRCA2, DNA repair associated decreases expression ISO Paraquat results in decreased expression of BRCA2 mRNA CTD PMID:28012437 NCBI chr12:503,660...544,754
Ensembl chr12:504,007...544,748 		JBrowse link
G Brf1 BRF1, RNA polymerase III transcription initiation factor subunit multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of BRF1 mRNA CTD PMID:18386188 NCBI chr 6:137,762,230...137,808,573
Ensembl chr 6:137,765,122...137,808,303 		JBrowse link
G Bsg basigin (Ok blood group) increases expression ISO Paraquat results in increased expression of BSG protein CTD PMID:29287252 NCBI chr 7:12,875,536...12,882,753
Ensembl chr 7:12,875,537...12,882,753 		JBrowse link
G Bst1 bone marrow stromal cell antigen 1 increases expression EXP Paraquat results in increased expression of BST1 mRNA CTD PMID:18198484 NCBI chr14:71,798,218...71,814,540
Ensembl chr14:71,798,651...71,814,523 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Paraquat results in increased expression of BTG2 mRNA CTD PMID:12595580 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BUB1 mRNA CTD PMID:28012437 NCBI chr 3:120,373,604...120,404,910
Ensembl chr 3:120,373,604...120,404,910 		JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of BUB1B mRNA CTD PMID:28012437 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458 		JBrowse link
G Ca3 carbonic anhydrase 3 affects expression EXP Paraquat affects the expression of CAR3 mRNA CTD PMID:15206577 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410 		JBrowse link
G Cacna1c calcium voltage-gated channel subunit alpha1 C increases expression EXP Paraquat results in increased expression of CACNA1C mRNA CTD PMID:18198484 NCBI chr 4:150,635,808...151,270,790
Ensembl chr 4:150,641,066...150,829,913 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E multiple interactions
increases expression		 ISO [Paraquat co-treated with Maneb] affects the expression of CACNA1E mRNA
Paraquat results in increased expression of CACNA1E mRNA		 CTD PMID:22563483 NCBI chr13:71,899,445...72,534,992
Ensembl chr13:71,906,702...72,367,980 		JBrowse link
G Cacnb3 calcium voltage-gated channel auxiliary subunit beta 3 increases expression EXP Paraquat results in increased expression of CACNB3 mRNA CTD PMID:18198484 NCBI chr 7:140,311,120...140,324,902
Ensembl chr 7:140,315,368...140,324,902 		JBrowse link
G Cacybp calcyclin binding protein multiple interactions
increases expression		 ISO [Paraquat co-treated with Maneb] results in increased expression of CACYBP mRNA
Paraquat results in increased expression of CACYBP mRNA		 CTD PMID:18386188 PMID:28619522 NCBI chr13:77,948,771...77,959,089
Ensembl chr13:77,948,771...77,959,110 		JBrowse link
G Calcr calcitonin receptor decreases expression EXP Paraquat results in decreased expression of CALCR mRNA CTD PMID:17077588 NCBI chr 4:28,627,439...28,702,559
Ensembl chr 4:28,627,442...28,702,559 		JBrowse link
G Calm1 calmodulin 1 multiple interactions
increases expression		 ISO [Maneb co-treated with Paraquat] results in increased expression of CALM1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CALM1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CALM1 mRNA]
Paraquat results in increased expression of CALM1 mRNA		 CTD PMID:23963992 PMID:31368498 NCBI chr 6:124,217,241...124,225,292
Ensembl chr 6:124,217,241...124,225,292 		JBrowse link
G Calm2 calmodulin 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of CALM2 mRNA CTD PMID:18386188 NCBI chr 6:11,067,675...11,080,078
Ensembl chr15:65,506,874...65,507,968 		JBrowse link
G Camp cathelicidin antimicrobial peptide multiple interactions ISO
EXP		 [Paraquat co-treated with Maneb] affects the expression of CAMP mRNA
[Paraquat co-treated with Maneb] results in decreased expression of CAMP mRNA		 CTD PMID:22563483 PMID:27460631 NCBI chr 8:117,930,557...117,932,371
Ensembl chr 8:117,930,546...117,932,518 		JBrowse link
G Capn1 calpain 1 multiple interactions
increases activity		 EXP
ISO		 Paraquat results in increased expression of and results in increased activity of CAPN1 protein
calpeptin inhibits the reaction [Paraquat results in increased activity of CAPN1 protein]		 CTD PMID:22678742 PMID:24509835 NCBI chr 1:221,346,081...221,370,965
Ensembl chr 1:221,346,066...221,370,322 		JBrowse link
G Capn11 calpain 11 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of CAPN11 mRNA CTD PMID:22563483 NCBI chr 9:17,728,845...17,750,357
Ensembl chr 9:17,728,816...17,750,363 		JBrowse link
G Capn2 calpain 2 multiple interactions EXP Paraquat results in increased expression of and results in increased activity of CAPN2 protein CTD PMID:22678742 NCBI chr13:100,878,649...100,928,811
Ensembl chr13:100,878,650...100,928,811 		JBrowse link
G Capn6 calpain 6 increases expression ISO Paraquat results in increased expression of CAPN6 mRNA CTD PMID:26345256 NCBI chr  X:115,049,113...115,073,824
Ensembl chr  X:115,049,154...115,073,890 		JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP Paraquat results in increased expression of CAR2 protein CTD PMID:24521700 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029 		JBrowse link
G Card6 caspase recruitment domain family, member 6 decreases expression ISO Paraquat results in decreased expression of CARD6 mRNA CTD PMID:18836921 NCBI chr 2:54,810,676...54,824,050
Ensembl chr 2:54,810,110...54,824,033 		JBrowse link
G Casp1 caspase 1 multiple interactions
increases expression
decreases activity		 EXP
ISO		 Glyburide inhibits the reaction [Paraquat results in increased expression of CASP1 protein]; procyanidin B2 inhibits the reaction [Paraquat results in increased expression of CASP1 protein]; Sodium Salicylate inhibits the reaction [Paraquat results in decreased activity of CASP1 protein]
Paraquat results in increased expression of CASP1 protein; Paraquat results in increased expression of CASP1 protein modified form
Paraquat results in increased expression of CASP1 mRNA; Paraquat results in increased expression of CASP1 protein
[Maneb co-treated with Paraquat] results in increased expression of CASP1 mRNA; [Paraquat co-treated with Maneb] results in increased cleavage of CASP1 protein; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased cleavage of CASP1 protein]; ITGAM protein affects the reaction [[Paraquat co-treated with Maneb] results in increased cleavage of CASP1 protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CASP1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CASP1 mRNA]; Silymarin inhibits the reaction [Paraquat results in increased expression of CASP1 protein modified form]; Silymarin inhibits the reaction [Paraquat results in increased expression of CASP1 protein]		 CTD PMID:17561093 PMID:18836921 PMID:23963992 PMID:25338942 PMID:29054699 PMID:30025709 PMID:32375810 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631 		JBrowse link
G Casp12 caspase 12 multiple interactions
increases activity
increases expression
increases degradation		 EXP Minocycline results in decreased degradation of [Paraquat results in increased expression of CASP12 protein]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of CASP12 mRNA]
Paraquat results in increased activity of CASP12 protein
Paraquat results in increased expression of CASP12 mRNA; Paraquat results in increased expression of CASP12 protein
Paraquat results in increased degradation of CASP12 protein		 CTD PMID:22245251 PMID:22678742 PMID:24912633 NCBI chr 8:2,658,892...2,686,160
Ensembl chr 8:2,659,865...2,686,160 		JBrowse link
G Casp2 caspase 2 decreases expression ISO Paraquat results in decreased expression of CASP2 mRNA CTD PMID:18836921 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
decreases expression
increases cleavage		 ISO
EXP		 AKT1 protein affects the reaction [Paraquat results in increased activity of CASP3 protein]; GPX1 protein affects the reaction [Paraquat results in increased activity of CASP3 protein]; GPX1 protein affects the reaction [Paraquat results in increased expression of CASP3 protein]; PARK7 protein affects the reaction [Paraquat results in increased cleavage of CASP3 protein]; Silymarin inhibits the reaction [Paraquat results in increased expression of CASP3 protein modified form]
Paraquat results in increased expression of CASP3 mRNA; Paraquat results in increased expression of CASP3 protein modified form
Paraquat results in decreased expression of CASP3 mRNA
Paraquat results in increased expression of CASP3 mRNA; Paraquat results in increased expression of CASP3 protein; Paraquat results in increased expression of CASP3 protein modified form
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [salvin inhibits the reaction [Paraquat results in increased activity of CASP3 protein]]; 3-methyladenine promotes the reaction [Paraquat results in increased activity of CASP3 protein]; [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of CASP3 mRNA]; [PTGDS protein results in decreased susceptibility to Paraquat] which results in decreased cleavage of CASP3 protein; Acetylcysteine inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; ATG5 protein promotes the reaction [Paraquat results in increased cleavage of and results in increased activity of CASP3 protein]; benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; GHRL protein inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; LGK974 inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Paraquat promotes the reaction [Trientine results in increased activity of CASP3 protein]; Paraquat results in increased cleavage of and results in increased activity of CASP3 protein; PRKN protein inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; PTGDS mutant form promotes the reaction [Paraquat results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [Paraquat results in increased expression of CASP3 protein modified form]; salubrinal inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; salvin inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; TLR9 protein promotes the reaction [Paraquat results in increased expression of CASP3 protein modified form]
Acetylcysteine inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; calpeptin inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; Cyclosporine inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; Dibucaine inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; diphenyleneiodonium inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; Edaravone inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; epigallocatechin gallate inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; fasudil inhibits the reaction [Paraquat results in increased expression of CASP3 mRNA]; Minocycline inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Sodium Salicylate inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; U 74389F inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]		 CTD PMID:11369509 PMID:12654481 PMID:16310883 PMID:17018646 PMID:17215068 PMID:17324951 PMID:17341480 PMID:17561093 PMID:17936647 PMID:18056701 PMID:18253895 PMID:18836921 PMID:19735704 PMID:20929985 PMID:21300143 PMID:21777615 PMID:22043816 PMID:22245251 PMID:22678742 PMID:22736252 PMID:22987761 PMID:23807224 PMID:23997112 PMID:24060684 PMID:24130211 PMID:24866057 PMID:24912633 PMID:25947082 PMID:26468117 PMID:26686574 PMID:27442881 PMID:28115273 PMID:28363843 PMID:28414160 PMID:28428137 PMID:28474156 PMID:28986289 PMID:29054699 PMID:30088170 PMID:30144575 PMID:30185695 PMID:30205152 PMID:30698896 PMID:30967525 PMID:31381934 PMID:31400064 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204 		JBrowse link
G Casp7 caspase 7 increases activity
multiple interactions
increases expression		 EXP
ISO		 Paraquat results in increased activity of CASP7 protein
CAT protein inhibits the reaction [Paraquat results in increased activity of CASP7 protein]
Paraquat results in increased expression of CASP7 mRNA
NFE2L2 mutant form inhibits the reaction [Paraquat results in increased activity of CASP7 protein]		 CTD PMID:17324951 PMID:18836921 PMID:22678742 PMID:24866057 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774 		JBrowse link
G Casp8 caspase 8 increases expression
increases cleavage
multiple interactions
decreases expression
increases activity		 ISO
EXP		 Paraquat results in increased expression of CASP8 mRNA; Paraquat results in increased expression of CASP8 mRNA alternative form
Paraquat results in increased cleavage of CASP8 protein
6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in increased expression of CASP8 protein modified form]; Paraquat promotes the reaction [TNFRSF10B protein binds to CASP8 protein]
Paraquat results in decreased expression of CASP8 mRNA
Paraquat results in increased activity of CASP8 protein
Sodium Salicylate inhibits the reaction [Paraquat results in increased activity of CASP8 protein]		 CTD PMID:17064354 PMID:17561093 PMID:20883675 PMID:24912633 PMID:26468117 PMID:28414160 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106 		JBrowse link
G Casp9 caspase 9 increases expression
multiple interactions
increases activity
decreases expression
increases cleavage		 ISO
EXP		 Paraquat results in increased expression of CASP9 mRNA; Paraquat results in increased expression of CASP9 mRNA alternative form; Paraquat results in increased expression of CASP9 protein
Paraquat results in increased expression of CASP9 protein modified form
[Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of CASP9 mRNA]; [PTGDS protein results in decreased susceptibility to Paraquat] which results in decreased cleavage of CASP9 protein; PRKN protein inhibits the reaction [Paraquat results in increased activity of CASP9 protein]; PTGDS mutant form promotes the reaction [Paraquat results in increased cleavage of CASP9 protein]; salvin inhibits the reaction [Paraquat results in increased activity of CASP9 protein]
Paraquat results in decreased expression of CASP9 mRNA
[Maneb co-treated with Paraquat] results in increased expression of CASP9 mRNA; [Paraquat co-treated with Maneb] results in increased expression of CASP9 protein; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CASP9 mRNA]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CASP9 protein]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CASP9 mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CASP9 protein]		 CTD PMID:17064354 PMID:18253895 PMID:18836921 PMID:20964710 PMID:22043816 PMID:22736252 PMID:23963992 PMID:24912633 PMID:26649146 PMID:26686574 PMID:27442881 PMID:30144575 PMID:30698896 PMID:31400064 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778 		JBrowse link
G Cat catalase affects response to substance
decreases expression
affects activity
decreases activity
increases expression
increases activity
multiple interactions
decreases response to substance
increases response to substance		 ISO
EXP		 CAT protein affects the susceptibility to Paraquat
Paraquat results in decreased expression of CAT protein
Paraquat affects the activity of CAT protein
Paraquat results in decreased activity of CAT protein
Paraquat results in increased expression of CAT mRNA; Paraquat results in increased expression of CAT protein
Paraquat results in increased activity of CAT protein
[Maneb co-treated with Paraquat] results in increased expression of CAT mRNA; [Mifepristone co-treated with Paraquat] results in decreased activity of CAT protein; [Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of CAT mRNA; [Prednisolone co-treated with pirfenidone] inhibits the reaction [Paraquat results in decreased activity of CAT protein]; betanin inhibits the reaction [Paraquat results in decreased activity of CAT protein]; Curcumin inhibits the reaction [Paraquat results in decreased activity of CAT protein]; embelin inhibits the reaction [Paraquat results in decreased expression of CAT protein]; NFE2L2 protein inhibits the reaction [[Mifepristone co-treated with Paraquat] results in decreased activity of CAT protein]; Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of CAT protein]; pirfenidone inhibits the reaction [Paraquat results in decreased activity of CAT protein]; Plant Extracts inhibits the reaction [Paraquat results in increased activity of CAT protein]; Unithiol promotes the reaction [Paraquat results in increased activity of CAT protein]; Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of CAT protein]
Paraquat results in decreased expression of CAT mRNA; Paraquat results in decreased expression of CAT protein
CAT protein results in decreased susceptibility to Paraquat
Curcumin inhibits the reaction [Paraquat results in decreased activity of CAT protein]; Hydroxylamine inhibits the reaction [CAT protein results in decreased susceptibility to Paraquat]; NFKB1 protein mutant form inhibits the reaction [Paraquat results in increased expression of CAT mRNA]; NFKBIA protein mutant form inhibits the reaction [Paraquat results in increased expression of CAT mRNA]; pirfenidone inhibits the reaction [Paraquat results in increased activity of CAT protein]; Resveratrol inhibits the reaction [Paraquat results in decreased activity of CAT protein]; SIRT1 protein affects the reaction [Paraquat affects the activity of CAT protein]; TO-901317 inhibits the reaction [Paraquat results in decreased activity of CAT protein]
[Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in decreased activity of CAT protein]; [NR1I2 protein results in decreased activity of CAT protein] which results in increased susceptibility to Paraquat; [Paraquat co-treated with Thioctic Acid] results in increased expression of CAT mRNA; [Plant Extracts co-treated with Paraquat] results in increased expression of CAT mRNA; [SOD1 protein co-treated with CAT protein] results in decreased susceptibility to Paraquat; CAT protein inhibits the reaction [[POR protein results in increased metabolism of Paraquat] which results in increased abundance of Hydrogen Peroxide]; CAT protein inhibits the reaction [Paraquat results in decreased expression of GCLC protein]; CAT protein inhibits the reaction [Paraquat results in decreased expression of NFE2L2 mRNA]; CAT protein inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; CAT protein inhibits the reaction [Paraquat results in increased activity of CASP7 protein]; CAT protein inhibits the reaction [Paraquat results in increased activity of ODC1 protein]; CAT protein inhibits the reaction [Paraquat results in increased expression of JUN mRNA]; CAT protein inhibits the reaction [Paraquat results in increased expression of MIR153 mRNA]; Dimethyl Sulfoxide inhibits the reaction [Paraquat results in increased expression of CAT mRNA]; IL1A protein promotes the reaction [Paraquat results in increased expression of CAT protein]; IL1B protein promotes the reaction [Paraquat results in increased expression of CAT protein]; Plant Extracts promotes the reaction [Paraquat results in increased expression of CAT mRNA]; TNF protein promotes the reaction [Paraquat results in increased expression of CAT protein]
CAT protein modified form results in increased susceptibility to Paraquat; CAT protein results in increased susceptibility to Paraquat		 CTD PMID:7662713 PMID:8317554 PMID:9169468 PMID:10699569 PMID:10751631 PMID:10754530 PMID:10959798 PMID:11178967 PMID:11325355 PMID:11728812 PMID:12180188 PMID:12826488 PMID:14759608 PMID:15177642 PMID:15190189 PMID:15754033 PMID:16195250 PMID:16677106 PMID:17107770 PMID:17215068 PMID:17935786 PMID:18620719 PMID:19486935 PMID:20095329 PMID:20553223 PMID:20883675 PMID:21215309 PMID:22736252 PMID:23649336 PMID:24141985 PMID:24376630 PMID:24799198 PMID:24812154 PMID:24866057 PMID:25169090 PMID:25461551 PMID:26468117 PMID:26598004 PMID:26649146 PMID:26708779 PMID:26935021 PMID:27993944 PMID:28480221 PMID:28696894 PMID:28921394 PMID:29273418 PMID:29859004 PMID:30243747 PMID:30744883 PMID:32020686 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058 		JBrowse link
G Cav1 caveolin 1 increases expression EXP Paraquat results in increased expression of CAV1 mRNA; Paraquat results in increased expression of CAV1 protein CTD PMID:26813466 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200 		JBrowse link
G Cbl Cbl proto-oncogene multiple interactions
increases phosphorylation		 EXP CBL protein affects the reaction [Paraquat results in decreased expression of PDGFRA protein]
Paraquat results in increased phosphorylation of CBL protein		 CTD PMID:17298174 NCBI chr 8:48,481,256...48,564,775
Ensembl chr 8:48,489,036...48,564,722 		JBrowse link
G Ccdc88a coiled coil domain containing 88A multiple interactions
increases expression		 ISO [Paraquat co-treated with Maneb] affects the expression of CCDC88A mRNA
Paraquat results in increased expression of CCDC88A mRNA		 CTD PMID:22563483 NCBI chr14:113,771,093...113,936,376
Ensembl chr14:113,867,209...113,932,263 		JBrowse link
G Cckbr cholecystokinin B receptor decreases expression EXP Paraquat results in decreased expression of CCKBR mRNA CTD PMID:17077588 NCBI chr 1:170,262,218...170,272,298
Ensembl chr 1:170,262,156...170,272,298 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 multiple interactions
increases expression		 ISO [Paraquat co-treated with Maneb] affects the expression of CCL19 mRNA
Paraquat results in increased expression of CCL19 mRNA		 CTD PMID:22563483 NCBI chr 5:58,181,025...58,182,969
Ensembl chr 5:58,181,026...58,183,017 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
affects expression
increases expression		 EXP
ISO		 [Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased secretion of CCL2 protein; Ambroxol affects the reaction [Paraquat results in increased expression of CCL2 mRNA]; SB 203580 inhibits the reaction [[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased secretion of CCL2 protein]
Paraquat affects the expression of CCL2 mRNA		 CTD PMID:16324872 PMID:21921364 PMID:24376630 PMID:26345256 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression
multiple interactions		 ISO Paraquat results in increased expression of CCL20 protein
PTPN6 protein inhibits the reaction [Paraquat results in increased expression of CCL20 protein]		 CTD PMID:18441283 NCBI chr 9:88,918,359...88,921,017
Ensembl chr 9:88,918,433...88,921,001 		JBrowse link
G Ccl21 C-C motif chemokine ligand 21 multiple interactions
increases expression		 ISO [Paraquat co-treated with Maneb] affects the expression of CCL21 mRNA; [Paraquat co-treated with Maneb] affects the expression of CCL21A mRNA
Paraquat results in increased expression of CCL21 mRNA; Paraquat results in increased expression of CCL21A mRNA		 CTD PMID:22563483 NCBI chr 5:58,197,678...58,198,782
Ensembl chr 5:58,197,680...58,198,782 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CCL3 mRNA]; Dapsone inhibits the reaction [Paraquat results in increased expression of CCL3 mRNA] CTD PMID:16324872 PMID:21765237 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066 		JBrowse link
G Ccn1 cellular communication network factor 1 increases expression ISO Paraquat results in increased expression of CCN1 mRNA CTD PMID:12595580 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
increases secretion
increases expression		 ISO
EXP		 [CCN2 protein co-treated with Paraquat] affects the expression of MMP2 mRNA; [CCN2 protein co-treated with Paraquat] affects the expression of MMP9 mRNA; [CCN2 protein co-treated with Paraquat] affects the expression of TIMP1 mRNA; [Paraquat co-treated with TGFB1 protein] results in increased expression of CCN2 mRNA; Saralasin inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; Saralasin inhibits the reaction [Paraquat results in increased expression of CCN2 protein]; TGFB1 protein promotes the reaction [Paraquat results in increased expression of CCN2 protein]; Triamcinolone Acetonide promotes the reaction [Paraquat results in increased expression of CCN2 mRNA]
Paraquat results in increased secretion of CCN2 protein
ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of CCN2 protein]
Paraquat results in increased expression of CCN2 mRNA; Paraquat results in increased expression of CCN2 protein
LY2109761 inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; LY2109761 inhibits the reaction [Paraquat results in increased secretion of CCN2 protein]; prolinedithiocarbamate inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; prolinedithiocarbamate inhibits the reaction [Paraquat results in increased expression of CCN2 protein]; Tacrolimus inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA]; Tacrolimus inhibits the reaction [Paraquat results in increased secretion of CCN2 protein]		 CTD PMID:12595580 PMID:15728566 PMID:16767377 PMID:20035857 PMID:23433149 PMID:25815693 PMID:25945502 PMID:26129822 PMID:26758514 PMID:27682480 PMID:33000210 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773 		JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNA2 mRNA CTD PMID:28012437 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNB1 mRNA CTD PMID:28012437 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221 		JBrowse link
G Ccnb2 cyclin B2 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNB2 mRNA CTD PMID:28012437 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Ccnc cyclin C increases expression ISO Paraquat results in increased expression of CCNC mRNA CTD PMID:20883675 NCBI chr 5:35,865,598...35,883,732
Ensembl chr 5:35,865,605...35,883,706 		JBrowse link
G Ccnd1 cyclin D1 affects expression
multiple interactions
decreases expression		 EXP
ISO		 Paraquat affects the expression of CCND1 mRNA
[Maneb co-treated with Paraquat] results in decreased expression of CCND1 mRNA
LGK974 inhibits the reaction [Paraquat results in decreased expression of CCND1 protein]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of CCND1 mRNA]		 CTD PMID:16854511 PMID:26887261 PMID:29859004 PMID:30171970 PMID:30205152 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325 		JBrowse link
G Ccnd2 cyclin D2 decreases expression
multiple interactions		 EXP
ISO		 Paraquat results in decreased expression of CCND2 mRNA
[Maneb co-treated with Paraquat] results in decreased expression of CCND2 mRNA		 CTD PMID:17935786 PMID:28619522 PMID:29859004 NCBI chr 4:159,674,885...159,697,207
Ensembl chr 4:159,674,885...159,697,207 		JBrowse link
G Ccnd3 cyclin D3 decreases expression EXP Paraquat results in decreased expression of CCND3 mRNA CTD PMID:17935786 NCBI chr 9:15,404,816...15,410,905
Ensembl chr 9:15,404,822...15,410,943 		JBrowse link
G Ccne1 cyclin E1 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNE1 mRNA CTD PMID:28012437 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980 		JBrowse link
G Ccne2 cyclin E2 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CCNE2 mRNA CTD PMID:28012437 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406 		JBrowse link
G Ccng1 cyclin G1 increases expression EXP Paraquat results in increased expression of CCNG1 mRNA CTD PMID:17935786 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325 		JBrowse link
G Ccs copper chaperone for superoxide dismutase increases response to substance ISO CCS gene mutant form results in increased susceptibility to Paraquat CTD PMID:10694572 NCBI chr 1:220,075,251...220,096,319
Ensembl chr 1:220,075,247...220,096,404 		JBrowse link
G Cd14 CD14 molecule increases expression ISO Paraquat results in increased expression of CD14 mRNA CTD PMID:28012437 NCBI chr18:29,560,341...29,562,290
Ensembl chr18:29,560,365...29,562,153 		JBrowse link
G Cd27 CD27 molecule decreases expression ISO Paraquat results in decreased expression of CD27 mRNA CTD PMID:18836921 NCBI chr 4:157,744,881...157,751,609
Ensembl chr 4:157,744,882...157,750,088 		JBrowse link
G Cd38 CD38 molecule decreases expression EXP Paraquat results in decreased expression of CD38 mRNA CTD PMID:18198484 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672 		JBrowse link
G Cd40 CD40 molecule increases expression ISO Paraquat results in increased expression of CD40 mRNA CTD PMID:18836921 NCBI chr 3:161,519,789...161,534,943
Ensembl chr 3:161,519,743...161,534,704 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) decreases expression EXP Paraquat results in decreased expression of CD44 mRNA CTD PMID:18198484 NCBI chr 3:92,695,083...92,783,820
Ensembl chr 3:92,696,313...92,783,658 		JBrowse link
G Cd47 Cd47 molecule increases expression
multiple interactions		 ISO Paraquat results in increased expression of CD47 protein
Paraquat results in increased expression of CD47 mRNA; Paraquat results in increased expression of CD47 protein
THBS1 protein affects the reaction [Paraquat results in increased expression of CD47 protein]		 CTD PMID:29287252 PMID:30419666 NCBI chr11:53,511,485...53,575,754
Ensembl chr11:53,514,595...53,575,175 		JBrowse link
G Cd68 Cd68 molecule decreases expression
multiple interactions		 ISO Paraquat results in decreased expression of CD68 mRNA
[MTHFR gene polymorphism affects the susceptibility to Paraquat] which results in increased expression of CD68 protein; [Paraquat co-treated with Maneb] results in increased expression of CD68 mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CD68 mRNA]		 CTD PMID:21371552 PMID:30726997 PMID:32169474 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640 		JBrowse link
G Cd70 Cd70 molecule decreases expression ISO Paraquat results in decreased expression of CD70 mRNA CTD PMID:18836921 NCBI chr 9:9,842,585...9,845,728
Ensembl chr 9:9,842,585...9,845,728 		JBrowse link
G Cd80 Cd80 molecule increases expression EXP Paraquat results in increased expression of CD80 mRNA CTD PMID:18198484 NCBI chr11:64,815,201...64,855,293
Ensembl chr11:64,827,635...64,855,353 		JBrowse link
G Cd86 CD86 molecule increases expression
decreases expression		 EXP
ISO		 Paraquat results in increased expression of CD86 mRNA
Paraquat results in increased expression of CD86 protein
Paraquat results in decreased expression of CD86 mRNA		 CTD PMID:24521700 PMID:28467894 PMID:31299241 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795 		JBrowse link
G Cd8b CD8b molecule decreases expression ISO Paraquat results in decreased expression of CD8B mRNA CTD PMID:21371552 NCBI chr 4:99,185,960...99,201,887
Ensembl chr 4:99,185,885...99,202,023 		JBrowse link
G Cdc20 cell division cycle 20 decreases expression
multiple interactions
increases expression		 EXP
ISO		 Paraquat results in decreased expression of CDC20 mRNA
[ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDC20 mRNA
Paraquat results in increased expression of CDC20 mRNA		 CTD PMID:18198484 PMID:26345256 PMID:28012437 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015 		JBrowse link
G Cdc25a cell division cycle 25A affects expression EXP Paraquat affects the expression of CDC25A mRNA CTD PMID:16854511 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519 		JBrowse link
G Cdc25b cell division cycle 25B decreases expression ISO Paraquat results in decreased expression of CDC25B mRNA CTD PMID:28012437 NCBI chr 3:123,731,539...123,741,696
Ensembl chr 3:123,731,539...123,741,339 		JBrowse link
G Cdc25c cell division cycle 25C multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDC25C mRNA CTD PMID:28012437 NCBI chr18:27,528,768...27,550,316
Ensembl chr18:27,528,354...27,550,224 		JBrowse link
G Cdc40 cell division cycle 40 increases expression ISO Paraquat results in increased expression of CDC40 mRNA CTD PMID:21371552 NCBI chr20:48,503,973...48,574,546
Ensembl chr20:48,503,973...48,574,546 		JBrowse link
G Cdh1 cadherin 1 decreases expression
multiple interactions		 EXP Paraquat results in decreased expression of CDH1 mRNA; Paraquat results in decreased expression of CDH1 protein
Anthocyanins inhibits the reaction [Paraquat results in decreased expression of CDH1 protein]; NFE2L2 protein promotes the reaction [Sirolimus inhibits the reaction [Paraquat results in decreased expression of CDH1 protein]]; Sirolimus inhibits the reaction [Paraquat results in decreased expression of CDH1 mRNA]; Sirolimus inhibits the reaction [Paraquat results in decreased expression of CDH1 protein]; sulforafan inhibits the reaction [Paraquat results in decreased expression of CDH1 protein]		 CTD PMID:25873302 PMID:28624451 PMID:30317802 PMID:30403199 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395 		JBrowse link
G Cdhr4 cadherin-related family member 4 decreases expression
multiple interactions		 ISO Paraquat results in decreased expression of CDHR4 mRNA
[Paraquat co-treated with Maneb] affects the expression of CDHR4 mRNA		 CTD PMID:22563483 NCBI chr 8:116,771,377...116,779,242 JBrowse link
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CDIPT mRNA CTD PMID:18386188 NCBI chr 1:198,409,186...198,413,497
Ensembl chr 1:198,409,360...198,413,497 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions
decreases expression		 ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDK1 mRNA; Paraquat affects the reaction [ATG7 protein affects the expression of CDK1 mRNA]; Paraquat affects the reaction [ATG7 protein affects the expression of CDK1 protein]
Paraquat results in decreased expression of CDK1 mRNA; Paraquat results in decreased expression of CDK1 protein		 CTD PMID:28012437 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDK2 mRNA; [Maneb co-treated with Paraquat] results in decreased expression of CDK2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CDK2 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CDK2 mRNA] CTD PMID:23963992 PMID:28012437 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of CDK5R1 mRNA CTD PMID:23017109 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255 		JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of CDK5RAP1 mRNA CTD PMID:23017109 NCBI chr 3:149,835,953...149,870,429
Ensembl chr 3:149,703,848...149,870,413 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of CDK5RAP2 mRNA; LRRK2 protein mutant form inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CDK5RAP2 mRNA]; SNCA protein inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CDK5RAP2 mRNA] CTD PMID:23017109 NCBI chr 5:86,387,238...86,554,108
Ensembl chr 5:86,387,078...86,554,102 		JBrowse link
G Cdk8 cyclin-dependent kinase 8 decreases expression ISO Paraquat results in decreased expression of CDK8 mRNA CTD PMID:21371552 NCBI chr12:10,496,273...10,561,335 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
decreases expression		 ISO Paraquat results in increased expression of CDKN1A mRNA; Paraquat results in increased expression of CDKN1A protein
[ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CDKN1A mRNA; [Maneb co-treated with Paraquat] results in increased expression of CDKN1A mRNA; ATG7 protein affects the reaction [Paraquat results in increased expression of CDKN1A protein]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CDKN1A mRNA]
Paraquat results in decreased expression of CDKN1A mRNA		 CTD PMID:12595580 PMID:20883675 PMID:21371552 PMID:23963992 PMID:24060684 PMID:28012437 PMID:31368498 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO Paraquat results in decreased expression of CDKN1C mRNA CTD PMID:21371552 NCBI chr 1:216,661,067...216,663,791
Ensembl chr 1:216,661,080...216,663,721 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression
multiple interactions		 EXP Paraquat results in increased expression of CDKN2A mRNA
[Maneb co-treated with Paraquat] results in increased expression of CDKN2A mRNA		 CTD PMID:29859004 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C increases expression ISO Paraquat results in increased expression of CDKN2C mRNA CTD PMID:28012437 NCBI chr 5:129,347,731...129,352,886
Ensembl chr 5:129,347,732...129,352,886 		JBrowse link
G Cdo1 cysteine dioxygenase type 1 affects expression EXP Paraquat affects the expression of CDO1 mRNA CTD PMID:16854511 NCBI chr18:40,702,027...40,716,901
Ensembl chr18:40,701,984...40,716,686 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO Paraquat results in increased expression of CEBPB mRNA CTD PMID:12595580 PMID:23613995 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta decreases expression
multiple interactions		 ISO Paraquat results in decreased expression of CEBPD mRNA
[Paraquat co-treated with Maneb] affects the expression of CEBPD mRNA		 CTD PMID:22563483 NCBI chr11:89,008,008...89,009,146
Ensembl chr11:89,008,008...89,009,146 		JBrowse link
G Cep290 centrosomal protein 290 multiple interactions
increases expression		 ISO [Paraquat co-treated with Maneb] affects the expression of CEP290 mRNA
Paraquat results in increased expression of CEP290 mRNA		 CTD PMID:22563483 NCBI chr 7:40,217,269...40,306,327
Ensembl chr 7:40,217,269...40,306,327 		JBrowse link
G Cfl1 cofilin 1 increases expression EXP Paraquat results in increased expression of CFL1 mRNA CTD PMID:17077588 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337 		JBrowse link
G Cftr CF transmembrane conductance regulator affects expression
affects splicing		 EXP
ISO		 Paraquat affects the expression of CFTR mRNA
Paraquat affects the splicing of CFTR exon		 CTD PMID:15206577 PMID:27111068 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676 		JBrowse link
G Chat choline O-acetyltransferase decreases activity
decreases expression		 EXP Paraquat results in decreased activity of CHAT protein
Paraquat results in decreased expression of CHAT mRNA		 CTD PMID:24521700 PMID:28916328 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131 		JBrowse link
G Chek1 checkpoint kinase 1 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of CHEK1 mRNA CTD PMID:28012437 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of CHRM2 mRNA CTD PMID:23017109 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090 		JBrowse link
G Chrna5 cholinergic receptor nicotinic alpha 5 subunit affects expression EXP Paraquat affects the expression of CHRNA5 mRNA CTD PMID:18198484 NCBI chr 8:59,561,817...59,590,172
Ensembl chr 8:59,561,721...59,590,172 		JBrowse link
G Chrna6 cholinergic receptor nicotinic alpha 6 subunit multiple interactions
affects expression		 ISO
EXP		 Nicotine inhibits the reaction [Paraquat results in decreased expression of [CHRNA6 protein binds to CHRNB2 protein]]; Paraquat results in decreased expression of [CHRNA6 protein binds to CHRNB2 protein]
Paraquat affects the expression of CHRNA6 mRNA		 CTD PMID:17227438 PMID:18198484 NCBI chr16:68,860,018...68,866,718
Ensembl chr16:68,860,018...68,866,718 		JBrowse link
G Chrna7 cholinergic receptor nicotinic alpha 7 subunit increases expression EXP Paraquat results in increased expression of CHRNA7 mRNA CTD PMID:18198484 NCBI chr 1:123,897,341...124,039,263
Ensembl chr 1:123,899,657...124,039,196 		JBrowse link
G Chrnb1 cholinergic receptor nicotinic beta 1 subunit increases expression EXP Paraquat results in increased expression of CHRNB1 mRNA CTD PMID:17077588 NCBI chr10:56,390,671...56,403,255
Ensembl chr10:56,390,671...56,403,188 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Nicotine inhibits the reaction [Paraquat results in decreased expression of [CHRNA6 protein binds to CHRNB2 protein]]; Paraquat results in decreased expression of [CHRNA6 protein binds to CHRNB2 protein] CTD PMID:17227438 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785 		JBrowse link
G Chrne cholinergic receptor nicotinic epsilon subunit increases expression EXP Paraquat results in increased expression of CHRNE mRNA CTD PMID:17077588 NCBI chr10:57,238,960...57,246,750
Ensembl chr10:57,238,946...57,243,435 		JBrowse link
G Chrng cholinergic receptor nicotinic gamma subunit affects expression EXP Paraquat affects the expression of CHRNG mRNA CTD PMID:18198484 NCBI chr 9:94,302,218...94,308,591 JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO [Paraquat co-treated with Maneb] results in increased phosphorylation of CHUK protein; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of CHUK protein] CTD PMID:29568078 NCBI chr 1:263,848,829...263,884,354
Ensembl chr 1:263,848,884...263,885,169 		JBrowse link
G Cidea cell death-inducing DFFA-like effector a increases expression ISO Paraquat results in increased expression of CIDEA mRNA CTD PMID:18836921 NCBI chr18:63,082,861...63,108,450
Ensembl chr18:63,098,144...63,108,051 		JBrowse link
G Cideb cell death-inducing DFFA-like effector b increases expression ISO Paraquat results in increased expression of CIDEB mRNA CTD PMID:18836921 NCBI chr15:34,439,844...34,444,244
Ensembl chr15:34,439,876...34,444,244 		JBrowse link
G Cirbp cold inducible RNA binding protein multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CIRBP mRNA CTD PMID:18386188 NCBI chr 7:12,400,066...12,405,054
Ensembl chr 7:12,401,207...12,405,022 		JBrowse link
G Clca1 chloride channel accessory 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of CLCA1 mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CLCA1 mRNA] CTD PMID:23963992 NCBI chr 2:250,897,980...250,923,711
Ensembl chr 2:250,897,969...250,923,744 		JBrowse link
G Cldn1 claudin 1 decreases expression ISO Paraquat results in decreased expression of CLDN1 protein CTD PMID:30698896 NCBI chr11:77,815,216...77,830,373
Ensembl chr11:77,815,181...77,830,416 		JBrowse link
G Clk3 CDC-like kinase 3 increases expression EXP Paraquat results in increased expression of CLK3 mRNA CTD PMID:16328009 NCBI chr 8:62,528,135...62,543,550
Ensembl chr 8:62,528,225...62,542,622 		JBrowse link
G Clpx caseinolytic mitochondrial matrix peptidase chaperone subunit X increases expression ISO Paraquat results in increased expression of CLPX mRNA CTD PMID:21371552 NCBI chr 8:70,789,137...70,843,133
Ensembl chr 8:70,789,256...70,843,123 		JBrowse link
G Clspn claspin decreases expression ISO Paraquat results in decreased expression of CLSPN mRNA CTD PMID:23613995 NCBI chr 5:144,577,670...144,617,507
Ensembl chr 5:144,581,427...144,616,335 		JBrowse link
G Clu clusterin multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CLU mRNA CTD PMID:18386188 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857 		JBrowse link
G Cma1 chymase 1 multiple interactions
increases expression		 ISO
EXP		 CMA1 protein promotes the reaction [Paraquat results in increased expression of ACTA2 protein]; CMA1 protein promotes the reaction [Paraquat results in increased expression of AGT protein modified form]; CMA1 protein promotes the reaction [Paraquat results in increased expression of TGFB1 protein]
Paraquat results in increased expression of CMA1 mRNA
Paraquat results in increased expression of CMA1 mRNA; Paraquat results in increased expression of CMA1 protein		 CTD PMID:18198484 PMID:19969051 NCBI chr15:34,601,037...34,603,819
Ensembl chr15:34,601,037...34,603,819 		JBrowse link
G Cmklr1 chemerin chemokine-like receptor 1 increases expression EXP Paraquat results in increased expression of CMKLR1 mRNA CTD PMID:17077588 NCBI chr12:48,743,556...48,796,582
Ensembl chr12:48,789,261...48,793,553 		JBrowse link
G Cmpk2 cytidine/uridine monophosphate kinase 2 increases expression ISO Paraquat results in increased expression of CMPK2 mRNA CTD PMID:21371552 NCBI chr 6:45,683,242...45,694,824
Ensembl chr 6:45,683,234...45,694,822 		JBrowse link
G Cnr2 cannabinoid receptor 2 decreases expression
multiple interactions		 EXP Paraquat results in decreased expression of CNR2 protein
1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Paraquat results in decreased expression of CNR2 protein]		 CTD PMID:24963491 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression		 EXP
ISO		 [Paraquat co-treated with Oxygen] results in increased expression of COL1A1 mRNA; Ambroxol affects the reaction [Paraquat results in increased expression of COL1A1 mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]; Thalidomide inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]; Thalidomide inhibits the reaction [Paraquat results in increased expression of COL1A1 protein]
Paraquat results in increased expression of COL1A1 mRNA; Paraquat results in increased expression of COL1A1 protein
enterotoxin C, staphylococcal analog inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]; Fingolimod Hydrochloride inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]; pirfenidone inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]; thymoquinone inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]
Saralasin inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]		 CTD PMID:12882763 PMID:17215068 PMID:19969051 PMID:20035857 PMID:21921364 PMID:24893116 PMID:25304964 PMID:25873302 PMID:26099602 PMID:26221080 PMID:26345256 PMID:27375216 PMID:29273418 PMID:30403199 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789 		JBrowse link
G Col2a1 collagen type II alpha 1 chain decreases expression ISO Paraquat results in decreased expression of COL2A1 mRNA CTD PMID:26108578 NCBI chr 7:139,454,945...139,484,403
Ensembl chr 7:139,455,242...139,483,997 		JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions
increases expression		 ISO
EXP		 ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]; ADIPOR1 protein promotes the reaction [ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]]; Saralasin inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]
enterotoxin C, staphylococcal analog inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]; Fingolimod Hydrochloride inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of COL3A1 mRNA]
Paraquat results in increased expression of COL3A1 mRNA; Paraquat results in increased expression of COL3A1 protein
Ambroxol affects the reaction [Paraquat results in increased expression of COL3A1 mRNA]; Losartan inhibits the reaction [Paraquat results in increased expression of COL3A1 protein]		 CTD PMID:20035857 PMID:21921364 PMID:24893116 PMID:25233898 PMID:25304964 PMID:25873302 PMID:25945502 PMID:26099602 PMID:26758514 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain multiple interactions
increases expression		 ISO pirfenidone inhibits the reaction [Paraquat results in increased expression of COL4A1 mRNA]; thymoquinone inhibits the reaction [Paraquat results in increased expression of COL4A1 mRNA] CTD PMID:27375216 PMID:29273418 NCBI chr16:83,522,162...83,632,153
Ensembl chr16:83,522,162...83,632,153 		JBrowse link
G Col6a1 collagen type VI alpha 1 chain increases expression ISO Paraquat results in increased expression of COL6A1 mRNA CTD PMID:26345256 NCBI chr20:12,657,913...12,676,370
Ensembl chr20:12,658,065...12,675,561 		JBrowse link
G Comt catechol-O-methyltransferase increases expression EXP Paraquat results in increased expression of COMT mRNA CTD PMID:17935786 NCBI chr11:86,715,981...86,735,630
Ensembl chr11:86,715,981...86,735,622 		JBrowse link
G Cope COPI coat complex subunit epsilon multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of COPE mRNA CTD PMID:18386188 NCBI chr16:20,863,141...20,873,516
Ensembl chr16:20,863,141...20,873,521 		JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 affects expression
increases expression
decreases expression		 EXP Paraquat affects the expression of COX4I1 mRNA
Paraquat results in increased expression of COX4I1 protein
Paraquat results in decreased expression of COX4I1 mRNA		 CTD PMID:15206577 PMID:18198484 PMID:24521700 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225 		JBrowse link
G Cox5a cytochrome c oxidase subunit 5A increases expression
multiple interactions		 EXP
ISO		 Paraquat results in increased expression of COX5A protein
[Maneb co-treated with Paraquat] results in decreased expression of COX5A protein; Levodopa inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX5A protein]; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX5A protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX5A protein]		 CTD PMID:23562983 PMID:24521700 NCBI chr 8:62,298,358...62,309,765
Ensembl chr 8:62,298,358...62,309,765 		JBrowse link
G Cox5b cytochrome c oxidase subunit 5B decreases expression
increases expression		 EXP Paraquat results in decreased expression of COX5B mRNA
Paraquat results in increased expression of COX5B protein		 CTD PMID:17077588 PMID:24521700 NCBI chr 9:43,259,706...43,262,039
Ensembl chr 9:43,259,709...43,262,040 		JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of COX6A1 mRNA CTD PMID:18386188 NCBI chr12:47,024,442...47,027,495
Ensembl chr12:47,024,442...47,027,495 		JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of COX6B1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX6B1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX6B1 mRNA] CTD PMID:23963992 NCBI chr 1:89,075,987...89,084,834
Ensembl chr 1:89,075,975...89,084,859
Ensembl chr 2:89,075,975...89,084,859 		JBrowse link
G Cox6c cytochrome c oxidase subunit 6C increases expression EXP Paraquat results in increased expression of COX6C protein CTD PMID:24521700 NCBI chr 7:74,723,177...74,735,650
Ensembl chr 7:74,723,179...74,735,650 		JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 decreases expression
multiple interactions		 EXP
ISO		 Paraquat results in decreased expression of COX7A2 mRNA
[Paraquat co-treated with Maneb] results in decreased expression of COX7A2 mRNA		 CTD PMID:17077588 PMID:18386188 NCBI chr 8:87,209,529...87,213,627
Ensembl chr 8:87,209,530...87,213,627 		JBrowse link
G Cox7a2l cytochrome c oxidase subunit 7A2 like multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of COX7A2L mRNA CTD PMID:18386188 NCBI chr 6:6,695,807...6,709,790
Ensembl chr 6:6,695,827...6,709,783 		JBrowse link
G Cplx1 complexin 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CPLX1 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of CPLX1 protein CTD PMID:17532186 NCBI chr14:2,194,895...2,226,610
Ensembl chr14:2,194,933...2,226,598 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression EXP Paraquat results in increased expression of CPT1A mRNA CTD PMID:18198484 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678 		JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain increases expression ISO Paraquat results in increased expression of CRADD mRNA CTD PMID:18836921 NCBI chr 7:36,395,665...36,408,588
Ensembl chr 7:36,395,665...36,408,588 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions		 ISO
EXP		 Paraquat results in increased phosphorylation of CREB1 protein
[Paraquat co-treated with Maneb] results in decreased expression of CREB1 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of CREB1 protein; [Paraquat co-treated with Maneb] results in decreased expression of CREB1 protein modified form
[Maneb co-treated with Paraquat] results in decreased expression of CREB1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CREB1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CREB1 mRNA]		 CTD PMID:16797015 PMID:23963992 PMID:27460631 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435 		JBrowse link
G Creb3 cAMP responsive element binding protein 3 increases expression ISO Paraquat results in increased expression of CREB3 mRNA CTD PMID:21371552 NCBI chr 5:59,063,532...59,068,196
Ensembl chr 5:59,063,531...59,068,188 		JBrowse link
G Crebbp CREB binding protein increases expression
decreases expression		 EXP
ISO		 Paraquat results in increased expression of CREBBP protein
Paraquat results in decreased expression of CREBBP mRNA		 CTD PMID:20478973 PMID:28619522 NCBI chr10:11,590,994...11,721,039
Ensembl chr10:11,595,044...11,721,039 		JBrowse link
G Crh corticotropin releasing hormone increases expression ISO Paraquat results in increased expression of CRH mRNA; Paraquat results in increased expression of CRH protein CTD PMID:30744883 NCBI chr 2:104,459,999...104,461,863
Ensembl chr 2:104,459,999...104,461,863 		JBrowse link
G Crip2 cysteine-rich protein 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CRIP2 mRNA CTD PMID:18386188 NCBI chr 6:137,953,545...137,958,491
Ensembl chr 6:137,953,545...137,958,490 		JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 affects expression EXP Paraquat affects the expression of CRISPLD2 mRNA CTD PMID:16854511 NCBI chr19:52,647,038...52,705,118
Ensembl chr19:52,647,070...52,705,131 		JBrowse link
G Crlf2 cytokine receptor-like factor 2 decreases expression
multiple interactions		 ISO Paraquat results in decreased expression of CRLF2 mRNA
[Paraquat co-treated with Maneb] affects the expression of CRLF2 mRNA		 CTD PMID:22563483 NCBI chr14:1,456,843...1,461,543
Ensembl chr14:1,456,844...1,461,543 		JBrowse link
G Crot carnitine O-octanoyltransferase multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CROT mRNA CTD PMID:18386188 NCBI chr 4:22,079,837...22,116,265
Ensembl chr 4:22,081,604...22,116,265 		JBrowse link
G Crtc2 CREB regulated transcription coactivator 2 decreases expression
multiple interactions		 ISO Paraquat results in decreased expression of CRTC2 mRNA
WNT1 protein inhibits the reaction [Paraquat results in decreased expression of CRTC2 mRNA]		 CTD PMID:30171970 NCBI chr 2:189,615,928...189,625,646
Ensembl chr 2:189,615,948...189,626,051 		JBrowse link
G Csf1r colony stimulating factor 1 receptor affects expression
multiple interactions
increases expression		 EXP
ISO		 Paraquat affects the expression of CSF1R mRNA
[Paraquat co-treated with Maneb] results in increased expression of CSF1R mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CSF1R mRNA]
Paraquat results in increased expression of CSF1R mRNA		 CTD PMID:15206577 PMID:17077588 PMID:18198484 PMID:21371552 PMID:32169474 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300 		JBrowse link
G Csf2 colony stimulating factor 2 increases expression ISO Paraquat results in increased expression of CSF2 mRNA CTD PMID:22938100 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070 		JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of CSF2RA mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CSF2RA mRNA] CTD PMID:32169474 NCBI chr14:1,462,292...1,467,264
Ensembl chr14:1,462,358...1,467,264 		JBrowse link
G Csf3 colony stimulating factor 3 increases expression ISO Paraquat results in increased expression of CSF3 protein CTD PMID:26988026 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157 		JBrowse link
G Csnk1g2 casein kinase 1, gamma 2 decreases expression ISO Paraquat results in decreased expression of CSNK1G2 mRNA CTD PMID:21371552 NCBI chr 7:11,944,957...11,963,268
Ensembl chr 7:11,944,958...11,963,268 		JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 increases expression ISO Paraquat results in increased expression of CSNK2A2 protein CTD PMID:26649146 NCBI chr19:9,972,537...10,012,043
Ensembl chr19:9,972,537...10,012,043 		JBrowse link
G Cspg4 chondroitin sulfate proteoglycan 4 affects expression EXP Paraquat affects the expression of CSPG4 mRNA CTD PMID:16854511 NCBI chr 8:61,532,465...61,567,510
Ensembl chr 8:61,532,465...61,567,510 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression
affects localization
decreases expression
decreases response to substance		 ISO
EXP		 CTNNB1 protein inhibits the reaction [Paraquat results in increased abundance of Reactive Oxygen Species]; Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of CTNNB1 protein]; Paraquat inhibits the reaction [CTNNB1 protein binds to MPZ promoter]; Paraquat inhibits the reaction [CTNNB1 protein binds to PMP22 promoter]
Paraquat results in increased expression of CTNNB1 protein
Febuxostat inhibits the reaction [Paraquat results in increased expression of CTNNB1 protein]
LGK974 inhibits the reaction [Paraquat affects the localization of CTNNB1 protein]; LGK974 inhibits the reaction [Paraquat results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; Paraquat results in increased expression of and results in decreased phosphorylation of CTNNB1 protein; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of CTNNB1 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of CTNNB1 protein]
Paraquat results in decreased expression of CTNNB1 mRNA; Paraquat results in decreased expression of CTNNB1 protein
CTNNB1 protein results in decreased susceptibility to Paraquat		 CTD PMID:23620592 PMID:26887261 PMID:27788593 PMID:30171970 PMID:30205152 PMID:30726711 NCBI chr 8:129,601,511...129,628,378
Ensembl chr 8:129,617,812...129,627,372 		JBrowse link
G Ctnnbip1 catenin, beta-interacting protein 1 increases expression ISO Paraquat results in increased expression of CTNNBIP1 mRNA CTD PMID:28619522 NCBI chr 5:166,464,170...166,513,030
Ensembl chr 5:166,464,252...166,513,027 		JBrowse link
G Ctnnd1 catenin delta 1 multiple interactions
decreases expression		 ISO mangiferin inhibits the reaction [Paraquat results in decreased expression of and affects the localization of CTNND1 protein]; mangiferin inhibits the reaction [Paraquat results in decreased expression of CTNND1 mRNA alternative form]; Paraquat results in decreased expression of and affects the localization of CTNND1 protein CTD PMID:24912632 NCBI chr 3:72,001,904...72,053,047
Ensembl chr 3:72,002,152...72,053,049 		JBrowse link
G Ctnnd2 catenin delta 2 decreases expression ISO Paraquat results in decreased expression of CTNND2 mRNA CTD PMID:21371552 NCBI chr 2:83,227,247...84,094,315
Ensembl chr 2:83,393,282...84,094,315 		JBrowse link
G Ctrb1 chymotrypsinogen B1 increases expression EXP Paraquat results in increased expression of CTRB mRNA CTD PMID:18198484 NCBI chr19:43,906,344...43,911,020
Ensembl chr19:43,906,292...43,911,057 		JBrowse link
G Ctsb cathepsin B decreases expression
multiple interactions
decreases activity		 ISO Paraquat results in decreased expression of CTSB mRNA
APOD protein inhibits the reaction [Paraquat results in decreased activity of CTSB protein]		 CTD PMID:16797015 PMID:28182653 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612 		JBrowse link
G Ctsc cathepsin C decreases expression ISO Paraquat results in decreased expression of CTSC mRNA CTD PMID:16797015 NCBI chr 1:151,918,514...151,949,979
Ensembl chr 1:151,918,571...151,949,983 		JBrowse link
G Ctsd cathepsin D decreases expression ISO Paraquat results in decreased expression of CTSD mRNA CTD PMID:16797015 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451 		JBrowse link
G Ctsh cathepsin H decreases expression ISO Paraquat results in decreased expression of CTSH mRNA CTD PMID:16797015 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287 		JBrowse link
G Ctsk cathepsin K increases expression ISO Paraquat results in increased expression of CTSK mRNA CTD PMID:26345256 NCBI chr 2:196,655,469...196,666,447
Ensembl chr 2:196,655,469...196,666,446 		JBrowse link
G Ctsl cathepsin L multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of CTSL mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CTSL mRNA] CTD PMID:23963992 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279 		JBrowse link
G Cul1 cullin 1 increases expression ISO Paraquat results in increased expression of CUL1 mRNA CTD PMID:21371552 PMID:28619522 NCBI chr 4:77,211,814...77,283,369
Ensembl chr 4:77,211,692...77,280,250 		JBrowse link
G Cx3cr1 C-X3-C motif chemokine receptor 1 decreases response to substance
multiple interactions		 ISO CX3CR1 protein results in decreased susceptibility to Paraquat
[LRRK2 protein results in increased susceptibility to Paraquat] which results in decreased expression of CX3CR1 protein		 CTD PMID:23299473 PMID:31174552 NCBI chr 8:128,740,756...128,754,514
Ensembl chr 8:128,740,756...128,754,514 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO Paraquat results in increased expression of CXCL10 mRNA CTD PMID:22230393 PMID:26345256 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930 		JBrowse link
G Cxcl11 C-X-C motif chemokine ligand 11 increases expression ISO Paraquat results in increased expression of CXCL11 mRNA CTD PMID:22230393 NCBI chr14:17,195,395...17,198,170
Ensembl chr14:17,195,014...17,198,291 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions		 EXP
ISO		 Paraquat results in increased expression of CXCL2 protein
Paraquat results in increased expression of CXCL2 mRNA; Paraquat results in increased expression of CXCL2 protein
1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [Paraquat results in increased expression of CXCL2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CXCL2 protein]; Paraquat promotes the reaction [endotoxin, Escherichia coli results in increased expression of CXCL2 protein]; SB 203580 inhibits the reaction [Paraquat promotes the reaction [endotoxin, Escherichia coli results in increased expression of CXCL2 protein]]; SB 203580 inhibits the reaction [Paraquat results in increased expression of CXCL2 protein]
[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased secretion of CXCL2 protein; SB 203580 inhibits the reaction [[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased secretion of CXCL2 protein]		 CTD PMID:12504350 PMID:16324872 PMID:16919916 PMID:24376630 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression
increases expression		 EXP
ISO		 Paraquat results in decreased expression of CXCL3 mRNA
Paraquat results in increased expression of CXCL1 protein		 CTD PMID:18198484 PMID:26988026 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 decreases expression EXP Paraquat results in decreased expression of CXCR4 mRNA CTD PMID:18198484 NCBI chr13:45,314,952...45,318,856
Ensembl chr13:45,314,933...45,318,878 		JBrowse link
G Cyb5a cytochrome b5 type A increases expression ISO Paraquat results in increased expression of CYB5A mRNA CTD PMID:21371552 NCBI chr18:81,694,818...81,726,821
Ensembl chr18:81,694,808...81,726,821 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of NOX2 mRNA; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOX2 mRNA]; diphenyleneiodonium inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOX2 mRNA]
[Paraquat co-treated with Maneb] results in increased expression of CYBB protein; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYBB protein]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYBB protein]		 CTD PMID:29568078 PMID:30797899 PMID:32375810 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547 		JBrowse link
G Cyc1 cytochrome c-1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CYC1 mRNA CTD PMID:18386188 NCBI chr 7:117,409,576...117,411,953
Ensembl chr 7:117,409,576...117,411,953 		JBrowse link
G Cycs cytochrome c, somatic multiple interactions
increases expression
affects localization		 ISO [Mifepristone co-treated with NFE2L2 protein] inhibits the reaction [Paraquat results in increased expression of CYCS mRNA]; salubrinal inhibits the reaction [Paraquat affects the localization of CYCS protein]
Paraquat results in increased expression of CYCS mRNA; Paraquat results in increased expression of CYCS protein		 CTD PMID:20929985 PMID:22736252 PMID:26649146 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326 		JBrowse link
G Cygb cytoglobin increases expression EXP Paraquat results in increased expression of CYGB mRNA CTD PMID:20388547 NCBI chr10:105,618,325...105,628,091
Ensembl chr10:105,618,326...105,628,091 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression
decreases expression		 EXP Paraquat results in increased expression of CYP11A1 mRNA
Paraquat results in decreased expression of CYP11A1 mRNA; Paraquat results in decreased expression of CYP11A1 protein		 CTD PMID:18198484 PMID:31128353 PMID:31610511 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression EXP Paraquat results in decreased expression of CYP17A1 mRNA; Paraquat results in decreased expression of CYP17A1 protein CTD PMID:31128353 PMID:31610511 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity EXP Paraquat results in decreased activity of CYP1A1 protein CTD PMID:17481832 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases activity
increases expression
multiple interactions		 EXP Paraquat results in increased activity of CYP1A2 protein
Paraquat results in increased expression of CYP1A2 mRNA; Paraquat results in increased expression of CYP1A2 protein
[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein; [Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP1A2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP1A2 mRNA]; Paraquat results in increased expression of and results in increased activity of CYP1A2 protein; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]; Silymarin inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP1A2 protein]; Silymarin inhibits the reaction [Paraquat results in increased expression of CYP1A2 mRNA]		 CTD PMID:20888808 PMID:23159886 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301 		JBrowse link
G Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 increases expression ISO Paraquat results in increased expression of CYP26B1 mRNA CTD PMID:21371552 NCBI chr 4:116,261,796...116,278,615
Ensembl chr 4:116,261,796...116,278,615 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression EXP Paraquat results in decreased expression of CYP2C6V1 mRNA CTD PMID:16328009 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
decreases expression		 ISO Ketoconazole inhibits the reaction [Paraquat results in decreased expression of CYP2D22 protein]; resveratrol inhibits the reaction [Paraquat results in decreased expression of CYP2D22 protein] CTD PMID:22334051 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
increases expression
increases activity		 ISO
EXP		 [Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA; [Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein; [Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]
Paraquat results in increased expression of CYP2E1 mRNA; Paraquat results in increased expression of CYP2E1 protein
[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein; [Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA; Acetylcysteine inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP2E1 mRNA]; Paraquat promotes the reaction [Zinc Sulfate results in increased expression of CYP2E1 mRNA]; Paraquat results in increased expression of and results in increased activity of CYP2E1 protein; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]; Silymarin inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP2E1 protein]; Silymarin inhibits the reaction [Paraquat results in increased expression of CYP2E1 mRNA]; Zinc Sulfate promotes the reaction [Paraquat results in increased expression of CYP2E1 mRNA]
Paraquat results in increased activity of CYP2E1 protein		 CTD PMID:16510128 PMID:20553223 PMID:20888808 PMID:20964710 PMID:23159886 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542 		JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 increases expression EXP Paraquat results in increased expression of CYP2F4 mRNA CTD PMID:16328009 NCBI chr 1:83,933,974...83,947,804
Ensembl chr 1:83,933,942...83,947,821 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases expression ISO Paraquat results in increased expression of CYP2J9 mRNA CTD PMID:21371552 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
increases expression		 EXP betanin inhibits the reaction [Paraquat results in increased expression of CYP3A2 mRNA] CTD PMID:24799198 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136 		JBrowse link
G Cyp46a1 cytochrome P450, family 46, subfamily a, polypeptide 1 increases expression ISO Paraquat results in increased expression of CYP46A1 mRNA CTD PMID:27788593 NCBI chr 6:132,242,328...132,273,788
Ensembl chr 6:132,242,328...132,273,787 		JBrowse link
G Cyp4a3 cytochrome P450, family 4, subfamily a, polypeptide 3 decreases expression EXP Paraquat results in decreased expression of CYP4A3 mRNA CTD PMID:17077588 NCBI chr 5:134,468,666...134,484,851
Ensembl chr 5:134,469,270...134,484,839 		JBrowse link
G Cyth3 cytohesin 3 increases expression ISO Paraquat results in increased expression of CYTH3 mRNA CTD PMID:12595580 NCBI chr12:12,877,559...12,907,771
Ensembl chr12:12,877,559...12,945,192 		JBrowse link
G Daam2 dishevelled associated activator of morphogenesis 2 decreases expression ISO Paraquat results in decreased expression of DAAM2 mRNA CTD PMID:28619522 NCBI chr 9:13,444,883...13,493,154
Ensembl chr 9:13,446,896...13,490,669 		JBrowse link
G Dap3 death associated protein 3 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of DAP3 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of DAP3 mRNA] CTD PMID:23963992 NCBI chr 2:188,225,607...188,255,324
Ensembl chr 2:188,225,613...188,252,725 		JBrowse link
G Dapk1 death associated protein kinase 1 increases expression ISO Paraquat results in increased expression of DAPK1 mRNA CTD PMID:18836921 NCBI chr17:4,297,038...4,454,941
Ensembl chr17:4,297,224...4,454,778 		JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of DBI mRNA CTD PMID:18386188 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908 		JBrowse link
G Dbp D-box binding PAR bZIP transcription factor increases expression ISO Paraquat results in increased expression of DBP mRNA CTD PMID:26345256 NCBI chr 1:101,687,896...101,692,845
Ensembl chr 1:101,687,855...101,692,846 		JBrowse link
G Ddah1 dimethylarginine dimethylaminohydrolase 1 increases expression EXP Paraquat results in increased expression of DDAH1 mRNA CTD PMID:20388547 NCBI chr 2:251,634,368...251,766,009
Ensembl chr 2:251,634,431...251,766,014 		JBrowse link
G Ddah2 dimethylarginine dimethylaminohydrolase 2 increases expression EXP Paraquat results in increased expression of DDAH2 mRNA CTD PMID:20388547 NCBI chr20:5,049,260...5,052,573
Ensembl chr20:5,049,496...5,052,585 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO Paraquat results in increased expression of DDB2 mRNA CTD PMID:23613995 NCBI chr 3:80,030,437...80,052,984
Ensembl chr 3:80,030,437...80,052,953 		JBrowse link
G Ddc dopa decarboxylase decreases expression ISO Paraquat results in decreased expression of DDC mRNA CTD PMID:21371552 NCBI chr14:91,905,919...91,996,816
Ensembl chr14:91,905,919...91,996,774 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions		 ISO
EXP		 Paraquat results in increased expression of DDIT3 mRNA; Paraquat results in increased expression of DDIT3 protein
Minocycline inhibits the reaction [Paraquat results in increased expression of DDIT3 protein]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of DDIT3 mRNA]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of DDIT3 protein]
EIF2S1 protein promotes the reaction [salubrinal inhibits the reaction [Paraquat results in increased expression of DDIT3 protein]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Paraquat results in increased expression of DDIT3 protein]; salubrinal inhibits the reaction [Paraquat results in increased expression of DDIT3 protein]		 CTD PMID:19735704 PMID:20883675 PMID:22245251 PMID:22678742 PMID:23613995 PMID:27442881 PMID:28986289 PMID:30185695 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Paraquat results in increased expression of DDIT4 mRNA CTD PMID:23613995 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382 		JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked multiple interactions
decreases expression		 ISO 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat inhibits the reaction [TNFRSF10B protein binds to DDX3X protein]]; 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in decreased expression of DDX3X protein modified form]; Paraquat inhibits the reaction [TNFRSF10B protein binds to DDX3X protein] CTD PMID:28414160 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995 		JBrowse link
G Ddx5 DEAD-box helicase 5 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of DDX5 mRNA CTD PMID:18386188 NCBI chr10:94,979,759...94,988,461
Ensembl chr10:94,980,928...94,988,461 		JBrowse link
G Dffa DNA fragmentation factor subunit alpha increases expression ISO Paraquat results in increased expression of DFFA mRNA CTD PMID:18836921 NCBI chr 5:165,922,893...165,935,822
Ensembl chr 5:165,922,915...165,935,821 		JBrowse link
G Dgkb diacylglycerol kinase, beta decreases expression ISO Paraquat results in decreased expression of DGKB mRNA CTD PMID:21371552 NCBI chr 6:57,516,351...58,277,385
Ensembl chr 6:57,516,713...58,277,279 		JBrowse link
G Dgkh diacylglycerol kinase, eta increases expression ISO Paraquat results in increased expression of DGKH mRNA CTD PMID:22563483 NCBI chr15:60,791,574...60,967,236
Ensembl chr15:60,803,098...60,959,769 		JBrowse link
G Dgki diacylglycerol kinase, iota increases expression
multiple interactions		 ISO Paraquat results in increased expression of DGKI mRNA
[Paraquat co-treated with Maneb] affects the expression of DGKI mRNA		 CTD PMID:22563483 NCBI chr 4:64,365,115...64,831,473
Ensembl chr 4:64,374,342...64,831,473 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO Paraquat results in decreased expression of DHCR24 mRNA CTD PMID:23315990 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression EXP Paraquat results in decreased expression of DHCR7 mRNA CTD PMID:16328009 NCBI chr 1:217,018,916...217,034,890
Ensembl chr 1:217,018,916...217,034,904 		JBrowse link
G Dhh desert hedgehog signaling molecule affects expression
decreases expression
increases expression		 EXP Paraquat affects the expression of DHH protein
Paraquat results in decreased expression of DHH mRNA
Paraquat results in increased expression of DHH protein		 CTD PMID:31128353 NCBI chr 7:140,575,288...140,580,783
Ensembl chr 7:140,575,288...140,580,783 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein multiple interactions
increases transport
affects localization
increases expression		 EXP
ISO		 Cyclosporine inhibits the reaction [Paraquat affects the localization of DIABLO protein]; Dibucaine inhibits the reaction [Paraquat affects the localization of DIABLO protein]; diphenyleneiodonium inhibits the reaction [Paraquat affects the localization of DIABLO protein]; epigallocatechin gallate inhibits the reaction [Paraquat results in increased expression of DIABLO protein]
Paraquat results in increased transport of DIABLO protein
LGK974 inhibits the reaction [Paraquat results in increased transport of DIABLO protein]		 CTD PMID:17936647 PMID:22245251 PMID:25947082 PMID:30205152 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330 		JBrowse link
G Dip2b disco-interacting protein 2 homolog B multiple interactions
increases expression		 ISO [Paraquat co-treated with Maneb] affects the expression of DIP2B mRNA
Paraquat results in increased expression of DIP2B mRNA		 CTD PMID:22563483 NCBI chr 7:141,702,034...141,878,945
Ensembl chr 7:141,702,038...141,879,951 		JBrowse link
G Dld dihydrolipoamide dehydrogenase decreases expression ISO Paraquat results in decreased expression of DLD mRNA CTD PMID:21371552 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694 		JBrowse link
G Dlg4 discs large MAGUK scaffold protein 4 multiple interactions
decreases expression		 EXP Estradiol inhibits the reaction [Paraquat results in decreased expression of DLG4 protein] CTD PMID:31715309 NCBI chr10:56,625,845...56,655,543
Ensembl chr10:56,627,411...56,653,599 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of DLL1 mRNA CTD PMID:23017109 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of DLST protein; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of DLST protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of DLST protein] CTD PMID:23562983 NCBI chr 6:108,936,534...108,961,322
Ensembl chr 6:108,936,664...108,959,803 		JBrowse link
G Dmd dystrophin increases response to substance ISO DMD gene mutant form results in increased susceptibility to Paraquat CTD PMID:10797403 NCBI chr  X:51,149,358...53,519,271
Ensembl chr  X:51,286,737...53,519,259 		JBrowse link
G Dmrta2 DMRT-like family A2 decreases expression
multiple interactions		 ISO Paraquat results in decreased expression of DMRTA2 mRNA
[Paraquat co-treated with Maneb] affects the expression of DMRTA2 mRNA		 CTD PMID:22563483 NCBI chr 5:129,754,295...129,760,045
Ensembl chr 5:129,756,149...129,758,986 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 decreases response to substance ISO DNAJB1 protein results in decreased susceptibility to Paraquat CTD PMID:11359866 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919 		JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of DNAJB6 mRNA CTD PMID:18386188 NCBI chr 4:2,711,329...2,774,969
Ensembl chr 4:2,711,385...2,774,890 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 decreases expression ISO Paraquat results in decreased expression of DNAJC3 mRNA CTD PMID:16797015 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329 		JBrowse link
G Dnm1l dynamin 1-like increases expression ISO Paraquat results in increased expression of DNM1L protein CTD PMID:28215578 NCBI chr11:88,830,968...88,882,271
Ensembl chr11:88,830,957...88,880,198 		JBrowse link
G Dnm2 dynamin 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of DNM2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of DNM2 mRNA] CTD PMID:23963992 NCBI chr 8:22,458,869...22,540,649
Ensembl chr 8:22,458,899...22,540,524 		JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression ISO Paraquat results in decreased expression of DNMT1 mRNA; Paraquat results in decreased expression of DNMT1 protein CTD PMID:31189234 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha decreases expression ISO Paraquat results in decreased expression of DNMT3A mRNA; Paraquat results in decreased expression of DNMT3A protein CTD PMID:31189234 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577 		JBrowse link
G Dnmt3b DNA methyltransferase 3 beta increases expression ISO Paraquat results in increased expression of DNMT3B CTD PMID:31189234 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786 		JBrowse link
G Dok4 docking protein 4 increases expression ISO Paraquat results in increased expression of DOK4 mRNA CTD PMID:21371552 NCBI chr19:10,563,423...10,574,094
Ensembl chr19:10,563,423...10,574,093 		JBrowse link
G Drd2 dopamine receptor D2 affects expression
increases expression
multiple interactions		 EXP
ISO		 Paraquat affects the expression of DRD2 mRNA
Paraquat results in increased expression of DRD2 mRNA
[SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of DRD2 mRNA		 CTD PMID:15206577 PMID:18198484 PMID:23017109 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642 		JBrowse link
G Drd4 dopamine receptor D4 affects expression
multiple interactions		 EXP
ISO		 Paraquat affects the expression of DRD4 mRNA
[Paraquat co-treated with Maneb] results in increased expression of DRD4 protein		 CTD PMID:15206577 PMID:22563483 NCBI chr 1:214,278,296...214,282,818
Ensembl chr 1:214,278,296...214,281,483 		JBrowse link
G Drd5 dopamine receptor D5 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of DRD5 mRNA CTD PMID:23017109 NCBI chr14:77,220,579...77,222,006
Ensembl chr14:77,220,579...77,222,006 		JBrowse link
G Dtx1 deltex E3 ubiquitin ligase 1 affects expression ISO Paraquat affects the expression of DTX1 mRNA CTD PMID:24053911 NCBI chr12:41,383,885...41,415,783
Ensembl chr12:41,385,241...41,414,754 		JBrowse link
G Duox1 dual oxidase 1 multiple interactions
increases expression		 ISO APOD protein affects the reaction [Paraquat results in increased expression of DUOX1 mRNA]
kaempferol inhibits the reaction [Paraquat results in increased expression of DUOX1 mRNA]		 CTD PMID:21688324 PMID:25177032 NCBI chr 3:114,251,794...114,286,827
Ensembl chr 3:114,253,637...114,286,802 		JBrowse link
G Duox2 dual oxidase 2 multiple interactions ISO [Quercetin co-treated with Paraquat] results in increased expression of DUOX2 mRNA CTD PMID:22996356 NCBI chr 3:114,218,187...114,237,808
Ensembl chr 3:114,218,193...114,235,933 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Paraquat results in increased expression of DUSP1 mRNA CTD PMID:12595580 PMID:23315990 PMID:28012437 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 decreases expression
multiple interactions		 EXP
ISO		 Paraquat results in decreased expression of DVL2 mRNA
Lithium Chloride inhibits the reaction [Paraquat results in decreased expression of DVL2 protein]
WNT1 protein inhibits the reaction [Paraquat results in decreased expression of DVL2 mRNA]; WNT1 protein inhibits the reaction [Paraquat results in decreased expression of DVL2 protein]
Paraquat results in decreased expression of DVL2 mRNA; Paraquat results in decreased expression of DVL2 protein		 CTD PMID:26887261 PMID:27788593 PMID:30171970 NCBI chr10:56,609,810...56,619,269
Ensembl chr10:56,610,051...56,619,269 		JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression
increases expression		 ISO
EXP		 Paraquat results in decreased expression of DYNLL1 mRNA
Paraquat results in increased expression of DYNLL1 mRNA		 CTD PMID:12595580 PMID:16328009 PMID:20388547 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572 		JBrowse link
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A increases expression ISO Paraquat results in increased expression of DYRK1A mRNA CTD PMID:21371552 NCBI chr11:34,858,339...34,958,733
Ensembl chr11:34,865,532...34,956,536 		JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of E2F1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of E2F1 mRNA] CTD PMID:23963992 NCBI chr 3:150,062,895...150,073,721
Ensembl chr 3:150,047,826...150,073,721 		JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 multiple interactions
increases expression		 ISO salubrinal inhibits the reaction [Paraquat results in increased expression of EDEM1 protein] CTD PMID:19735704 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779 		JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression		 EXP
ISO		 green tea extract AR25 inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA]; green tea extract AR25 inhibits the reaction [Paraquat results in increased expression of EDN1 protein]
Acetylcysteine inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA]; Dapsone inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA]
Paraquat results in increased expression of EDN1 mRNA; Paraquat results in increased expression of EDN1 protein		 CTD PMID:17235729 PMID:21765237 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324 		JBrowse link
G Ednra endothelin receptor type A affects expression EXP Paraquat affects the expression of EDNRA mRNA CTD PMID:16854511 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of EEF1A1 mRNA CTD PMID:18386188 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818 		JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 decreases expression ISO Paraquat results in decreased expression of EEF1A2 mRNA CTD PMID:21371552 NCBI chr 3:176,657,104...176,666,282
Ensembl chr 3:176,657,107...176,666,282 		JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of EEF1G mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of EEF1G mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of EEF1G mRNA] CTD PMID:23963992 NCBI chr 1:225,163,391...225,173,997
Ensembl chr 1:225,163,391...225,173,995 		JBrowse link
G Eef2k eukaryotic elongation factor-2 kinase decreases expression ISO Paraquat results in decreased expression of EEF2K mRNA CTD PMID:28012437 NCBI chr 1:190,780,211...190,839,926
Ensembl chr 1:190,780,236...190,842,324 		JBrowse link
G Efnb1 ephrin B1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of EFNB1 mRNA CTD PMID:23017109 NCBI chr  X:68,891,227...68,904,034
Ensembl chr  X:68,891,227...68,904,038 		JBrowse link
G Egfr epidermal growth factor receptor decreases expression EXP Paraquat results in decreased expression of EGFR protein CTD PMID:17298174 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796 		JBrowse link
G Egln2 egl-9 family hypoxia-inducible factor 2 decreases expression ISO Paraquat results in decreased expression of EGLN2 mRNA CTD PMID:21371552 NCBI chr 1:83,969,456...83,977,665
Ensembl chr 1:83,969,457...83,977,236 		JBrowse link
G Egr1 early growth response 1 increases expression ISO Paraquat results in increased expression of EGR1 mRNA CTD PMID:20883675 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429 		JBrowse link
G Egr4 early growth response 4 multiple interactions
decreases expression		 ISO [Paraquat co-treated with Maneb] affects the expression of EGR4 mRNA
Paraquat results in decreased expression of EGR4 mRNA		 CTD PMID:22563483 NCBI chr 4:117,293,620...117,296,082
Ensembl chr 4:117,293,620...117,296,082 		JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO Paraquat results in increased phosphorylation of EIF2A protein CTD PMID:20929985 NCBI chr 2:148,722,343...148,755,781
Ensembl chr 2:148,722,231...148,755,520 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
increases expression		 EXP
ISO		 Paraquat results in increased phosphorylation of EIF2AK3 protein
Paraquat results in increased expression of EIF2AK3 protein modified form		 CTD PMID:22245251 PMID:27442881 PMID:28986289 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation
multiple interactions
increases expression		 EXP
ISO		 Paraquat results in increased phosphorylation of EIF2S1 protein
EIF2S1 protein promotes the reaction [salubrinal inhibits the reaction [Paraquat results in increased expression of DDIT3 protein]]; EIF2S1 protein promotes the reaction [salubrinal inhibits the reaction [Paraquat results in increased expression of HSPA5 protein]]; salubrinal promotes the reaction [Paraquat results in increased expression of EIF2S1 protein modified form]		 CTD PMID:22245251 PMID:27442881 PMID:28986289 NCBI chr 6:102,048,372...102,073,041
Ensembl chr 6:102,048,372...102,073,041 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 increases expression ISO Paraquat results in increased expression of EIF4EBP1 mRNA CTD PMID:12595580 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248 		JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of EIF4G2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of EIF4G2 mRNA] CTD PMID:23963992 NCBI chr 1:175,883,362...175,895,510
Ensembl chr 1:175,883,363...175,895,510 		JBrowse link
G Elavl1 ELAV like RNA binding protein 1 affects localization ISO Paraquat affects the localization of ELAVL1 protein CTD PMID:22879928 NCBI chr12:2,461,502...2,502,432
Ensembl chr12:2,461,502...2,502,432 		JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ELK1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ELK1 mRNA] CTD PMID:23963992 NCBI chr  X:1,287,875...1,304,822
Ensembl chr  X:1,297,099...1,304,822 		JBrowse link
G Eln elastin increases expression ISO Paraquat results in increased expression of ELN mRNA CTD PMID:17215068 PMID:26345256 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863 		JBrowse link
G Elp1 elongator acetyltransferase complex subunit 1 increases expression ISO Paraquat results in increased expression of ELP1 mRNA CTD PMID:21371552 NCBI chr 5:73,503,406...73,552,798
Ensembl chr 5:73,503,407...73,552,798 		JBrowse link
G Eno1 enolase 1 multiple interactions
decreases expression		 ISO [Maneb co-treated with Paraquat] results in increased expression of ENO1 protein; [Paraquat co-treated with Maneb] results in decreased expression of ENO1 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of ENO1 protein; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of ENO1 protein]
Paraquat results in decreased expression of ENO1 mRNA; Paraquat results in decreased expression of ENO1 protein		 CTD PMID:17532186 PMID:18386188 PMID:23562983 PMID:27111068 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609 		JBrowse link
G Eno2 enolase 2 increases expression
multiple interactions
decreases expression		 ISO
EXP		 Paraquat results in increased expression of ENO2 mRNA alternative form
[Maneb co-treated with Paraquat] results in increased expression of ENO2 protein
Paraquat results in decreased expression of ENO2 protein		 CTD PMID:17064354 PMID:18198484 PMID:23562983 PMID:24521700 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047 		JBrowse link
G Epn2 epsin 2 increases expression ISO Paraquat results in increased expression of EPN2 mRNA CTD PMID:21371552 NCBI chr10:47,795,496...47,857,373
Ensembl chr10:47,795,524...47,857,326 		JBrowse link
G Epo erythropoietin multiple interactions ISO EPO protein inhibits the reaction [SOD2 gene mutant form results in increased susceptibility to Paraquat] CTD PMID:16288465 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266 		JBrowse link
G Eps8 epidermal growth factor receptor pathway substrate 8 decreases expression ISO Paraquat results in decreased expression of EPS8 mRNA CTD PMID:21371552 NCBI chr 4:171,475,155...171,645,620
Ensembl chr 4:171,475,567...171,591,882 		JBrowse link
G Epx eosinophil peroxidase multiple interactions
decreases expression		 ISO APOD protein affects the reaction [Paraquat results in decreased expression of EPX mRNA] CTD PMID:21688324 NCBI chr10:75,160,690...75,171,774
Ensembl chr10:75,160,690...75,171,774 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions
decreases response to substance		 ISO NFE2L2 protein affects the reaction [ERBB2 protein results in decreased susceptibility to Paraquat] CTD PMID:25467193 NCBI chr10:86,367,596...86,391,728
Ensembl chr10:86,367,596...86,391,728 		JBrowse link
G Erbb3 erb-b2 receptor tyrosine kinase 3 decreases expression ISO Paraquat results in decreased expression of ERBB3 mRNA CTD PMID:16797015 NCBI chr 7:2,989,202...3,010,610
Ensembl chr 7:2,989,340...3,010,350 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 increases expression ISO Paraquat results in increased expression of ERBB4 mRNA CTD PMID:22563483 NCBI chr 9:75,021,790...76,178,936
Ensembl chr 9:75,021,790...75,528,644 		JBrowse link
G Ercc1 ERCC excision repair 1, endonuclease non-catalytic subunit affects splicing ISO Paraquat affects the splicing of ERCC1 mRNA CTD PMID:23613995 NCBI chr 1:80,256,973...80,268,198
Ensembl chr 1:80,256,973...80,268,198 		JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor increases response to substance ISO ERCC6 gene mutant form results in increased susceptibility to Paraquat CTD PMID:12509265 PMID:15340056 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610 		JBrowse link
G Ergic2 ERGIC and golgi 2 decreases expression
increases expression		 ISO Paraquat results in decreased expression of ERGIC2 mRNA
Paraquat results in increased expression of ERGIC2 mRNA		 CTD PMID:21371552 NCBI chr 4:182,569,086...182,600,258
Ensembl chr 4:182,569,089...182,600,258 		JBrowse link
G Ermp1 endoplasmic reticulum metallopeptidase 1 increases expression ISO Paraquat results in increased expression of ERMP1 mRNA CTD PMID:21371552 NCBI chr 1:247,784,830...247,821,771
Ensembl chr 1:247,787,582...247,821,728 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression
increases phosphorylation		 ISO
EXP		 Paraquat promotes the reaction [MAP3K5 protein results in increased phosphorylation of ERN1 protein]
Paraquat results in increased expression of ERN1 protein modified form
Paraquat results in increased phosphorylation of ERN1 protein		 CTD PMID:20929985 PMID:22245251 PMID:28986289 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914 		JBrowse link
G Esr1 estrogen receptor 1 decreases activity EXP Paraquat results in decreased activity of ESR1 protein CTD PMID:31715309 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796 		JBrowse link
G Esrra estrogen related receptor, alpha decreases expression ISO Paraquat results in decreased expression of ESRRA mRNA CTD PMID:12595580 NCBI chr 1:222,168,729...222,178,842
Ensembl chr 1:222,168,730...222,178,725 		JBrowse link
G Etl4 enhancer trap locus 4 increases expression
multiple interactions		 ISO Paraquat results in increased expression of ETL4 mRNA
[Paraquat co-treated with Maneb] affects the expression of ETL4 mRNA		 CTD PMID:22563483 NCBI chr17:87,173,265...87,681,268
Ensembl chr17:87,274,944...87,681,317 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor decreases expression EXP Paraquat results in decreased expression of ETS1 mRNA CTD PMID:18198484 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625 		JBrowse link
G F2 coagulation factor II increases expression EXP Paraquat results in increased expression of F2 mRNA CTD PMID:18198484 NCBI chr 3:80,529,468...80,542,993
Ensembl chr 3:80,529,428...80,543,031 		JBrowse link
G Faah fatty acid amide hydrolase increases expression EXP Paraquat results in increased expression of FAAH mRNA CTD PMID:18198484 NCBI chr 5:134,852,899...134,872,095
Ensembl chr 5:134,852,875...134,871,775 		JBrowse link
G Fabp5 fatty acid binding protein 5 increases expression ISO Paraquat results in increased expression of FABP5 mRNA CTD PMID:21371552 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378 		JBrowse link
G Fadd Fas associated via death domain decreases expression ISO Paraquat results in decreased expression of FADD mRNA CTD PMID:18836921 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628 		JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO Paraquat results in decreased expression of FADS2 mRNA CTD PMID:21371552 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524 		JBrowse link
G Fanca FA complementation group A multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of FANCA mRNA CTD PMID:28012437 NCBI chr19:56,067,548...56,126,075
Ensembl chr19:56,067,548...56,126,063 		JBrowse link
G Fancb FA complementation group B multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of FANCB mRNA CTD PMID:28012437 NCBI chr  X:31,124,018...31,140,790
Ensembl chr  X:31,124,018...31,140,711 		JBrowse link
G Fancd2 FA complementation group D2 multiple interactions ISO [ATG7 protein affects the susceptibility to Paraquat] which affects the expression of FANCD2 mRNA CTD PMID:28012437 NCBI chr 4:145,489,869...145,551,479
Ensembl chr 4:145,489,869...145,551,479 		JBrowse link
G Fas Fas cell surface death receptor increases expression
multiple interactions		 ISO Paraquat results in increased expression of FAS mRNA
[Maneb co-treated with Paraquat] results in increased expression of FAS mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of FAS mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of FAS mRNA]		 CTD PMID:18836921 PMID:23963992 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790 		JBrowse link
G Faslg Fas ligand increases expression ISO Paraquat results in increased expression of FASL mRNA
Paraquat results in increased expression of FASLG mRNA		 CTD PMID:9657385 PMID:17215068 PMID:18836921 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705 		JBrowse link
G Fat3 FAT atypical cadherin 3 increases expression ISO Paraquat results in increased expression of FAT3 mRNA CTD PMID:22563483 NCBI chr 8:14,417,039...15,011,596
Ensembl chr 8:14,417,584...14,880,644 		JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of FEZ1 mRNA CTD PMID:23017109 NCBI chr 8:39,305,128...39,350,270
Ensembl chr 8:39,305,128...39,350,270 		JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression ISO Paraquat results in increased expression of FGF1 mRNA CTD PMID:16324872 NCBI chr18:32,273,830...32,359,831
Ensembl chr18:32,273,770...32,359,824 		JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression
decreases secretion
multiple interactions		 EXP
ISO		 Paraquat results in increased expression of FGF2 mRNA
Paraquat results in decreased secretion of FGF2 protein
Oxygen inhibits the reaction [Paraquat results in increased expression of FGF2 mRNA]		 CTD PMID:18198484 PMID:26722498 PMID:30698896 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of FGFR3 mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of FGFR3 mRNA] CTD PMID:23963992 NCBI chr14:82,272,322...82,287,739
Ensembl chr14:82,273,070...82,287,706 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 multiple interactions
affects response to substance		 ISO [Paraquat co-treated with Maneb] results in decreased expression of FKBP4 mRNA
FKBP4 protein affects the susceptibility to Paraquat		 CTD PMID:18386188 PMID:20713718 NCBI chr 4:161,748,993...161,757,447
Ensembl chr 4:161,748,993...161,757,447 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 increases expression
multiple interactions
affects expression		 ISO
EXP		 Paraquat results in increased expression of FKBP5 mRNA
[Paraquat co-treated with Maneb] results in decreased expression of FKBP5 mRNA
Paraquat affects the expression of FKBP5 mRNA		 CTD PMID:12595580 PMID:16854511 PMID:18386188 NCBI chr20:7,976,704...8,097,290
Ensembl chr20:7,976,713...8,019,020 		JBrowse link
G Fn1 fibronectin 1 decreases expression
multiple interactions
increases expression		 ISO
EXP		 Paraquat results in decreased expression of FN1 mRNA
THBS1 protein affects the reaction [Paraquat results in increased expression of FN1 protein]
Paraquat results in increased expression of FN1 mRNA; Paraquat results in increased expression of FN1 protein
prolinedithiocarbamate inhibits the reaction [Paraquat results in increased expression of FN1 mRNA]		 CTD PMID:16797015 PMID:17215068 PMID:23803522 PMID:25873302 PMID:26345256 PMID:29495171 PMID:30317802 PMID:30419666 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO
EXP		 [Maneb co-treated with Paraquat] results in increased expression of FOS mRNA; Paraquat promotes the reaction [JUN protein binds to FOS protein]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of FOS mRNA]
Paraquat results in increased expression of FOS mRNA
[Paraquat co-treated with Maneb] results in decreased expression of FOS mRNA; [Paraquat co-treated with Maneb] results in decreased expression of FOS protein
[Paraquat co-treated with SOD2 protein] results in increased expression of FOS mRNA		 CTD PMID:10464329 PMID:11728812 PMID:17048122 PMID:23963992 PMID:27460631 PMID:29441825 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299 		JBrowse link
G Foxm1 forkhead box M1 decreases expression ISO Paraquat results in decreased expression of FOXM1 mRNA CTD PMID:23315990 NCBI chr 4:161,685,236...161,697,633
Ensembl chr 4:161,685,258...161,696,305 		JBrowse link
G Foxo3 forkhead box O3 multiple interactions
affects expression
increases response to substance		 ISO FOXO3 mutant form inhibits the reaction [Paraquat results in increased expression of BCL2L11 mRNA]
Paraquat affects the expression of FOXO3 mRNA
FOXO3 protein results in increased susceptibility to Paraquat		 CTD PMID:23620592 PMID:29287252 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144 		JBrowse link
G Fstl1 follistatin-like 1 multiple interactions
increases expression		 ISO plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of FSTL1 mRNA]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in increased expression of FSTL1 protein]
Paraquat results in increased expression of FSTL1 mRNA; Paraquat results in increased expression of FSTL1 protein		 CTD PMID:26758514 NCBI chr11:65,791,196...65,845,721
Ensembl chr11:65,782,567...65,845,418 		JBrowse link
G Ftl1 ferritin light chain 1 multiple interactions
increases expression		 ISO Paraquat promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]]
Paraquat results in increased expression of FTL1 mRNA; Paraquat results in increased expression of FTL1 protein		 CTD PMID:12644586 PMID:28542246 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829 		JBrowse link
G Ftmt ferritin mitochondrial multiple interactions ISO Paraquat promotes the reaction [Iron binds to [FTL protein binds to FTMT protein]] CTD PMID:12644586 NCBI chr18:47,294,292...47,295,541
Ensembl chr18:47,294,292...47,295,541 		JBrowse link
G Fut2 fucosyltransferase 2 increases expression EXP Paraquat results in increased expression of FUT2 mRNA CTD PMID:17077588 NCBI chr 1:101,631,633...101,651,668
Ensembl chr 1:101,631,635...101,651,668 		JBrowse link
G Fxyd6 FXYD domain-containing ion transport regulator 6 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of FXYD6 mRNA CTD PMID:18386188 NCBI chr 8:49,676,520...49,703,419
Ensembl chr 8:49,676,540...49,703,419 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions
affects expression
increases activity		 EXP FYN protein affects the reaction [Paraquat results in decreased expression of PDGFRA protein]
Paraquat affects the expression of FYN mRNA
Paraquat results in increased activity of FYN protein		 CTD PMID:15206577 PMID:17298174 NCBI chr20:44,436,354...44,630,316
Ensembl chr20:44,436,403...44,630,317 		JBrowse link
G Fzd1 frizzled class receptor 1 decreases expression
multiple interactions		 EXP
ISO		 Paraquat results in decreased expression of FZD1 mRNA
Paraquat results in decreased expression of FZD1 mRNA; Paraquat results in decreased expression of FZD1 protein
WNT1 protein inhibits the reaction [Paraquat results in decreased expression of FZD1 mRNA]		 CTD PMID:26887261 PMID:30171970 NCBI chr 4:26,470,864...26,475,262
Ensembl chr 4:26,470,864...26,475,262 		JBrowse link
G Fzd4 frizzled class receptor 4 decreases expression
multiple interactions		 ISO Paraquat results in decreased expression of FZD4 mRNA
WNT1 protein inhibits the reaction [Paraquat results in decreased expression of FZD4 mRNA]
Paraquat results in decreased expression of FZD4 mRNA; Paraquat results in decreased expression of FZD4 protein		 CTD PMID:28619522 PMID:30171970 NCBI chr 1:153,589,471...153,598,376
Ensembl chr 1:153,589,471...153,598,375 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases activity EXP Paraquat results in increased activity of G6PDX protein CTD PMID:10699569 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926 		JBrowse link
G Gab1 GRB2-associated binding protein 1 decreases expression
multiple interactions		 ISO Paraquat results in decreased expression of GAB1 mRNA
APOD protein affects the reaction [Paraquat results in decreased expression of GAB1 mRNA]		 CTD PMID:21688324 NCBI chr19:30,794,290...30,903,819
Ensembl chr19:30,794,571...30,902,008 		JBrowse link
G Gabarapl1 GABA type A receptor associated protein like 1 increases expression ISO Paraquat results in increased expression of GABARAPL1 mRNA CTD PMID:12595580 NCBI chr 4:163,293,724...163,302,866
Ensembl chr 4:163,293,724...163,302,858 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 decreases expression ISO
EXP		 Paraquat results in decreased expression of GABBR1 mRNA
Paraquat results in decreased expression of GABBR1 protein		 CTD PMID:21371552 PMID:24521700 NCBI chr20:1,955,344...1,984,907
Ensembl chr20:1,955,359...1,984,863 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 increases expression EXP Paraquat results in increased expression of GABRA4 mRNA CTD PMID:18198484 NCBI chr14:39,154,072...39,230,994
Ensembl chr14:39,154,529...39,231,695 		JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of GABRA6 mRNA CTD PMID:22563483 NCBI chr10:27,847,447...27,862,896
Ensembl chr10:27,847,439...27,862,868 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 decreases expression EXP Paraquat results in decreased expression of GABRB1 mRNA CTD PMID:18198484 NCBI chr14:38,631,192...39,112,598
Ensembl chr14:38,643,385...39,112,600 		JBrowse link
G Gabrd gamma-aminobutyric acid type A receptor subunit delta decreases expression EXP Paraquat results in decreased expression of GABRD mRNA CTD PMID:19146868 NCBI chr 5:172,797,478...172,809,374
Ensembl chr 5:172,797,450...172,809,353 		JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression EXP Paraquat results in decreased expression of GAD1 mRNA CTD PMID:17493592 NCBI chr 3:56,861,440...56,902,139
Ensembl chr 3:56,861,396...56,902,157 		JBrowse link
G Gad2 glutamate decarboxylase 2 decreases expression EXP Paraquat results in decreased expression of GAD2 mRNA; Paraquat results in decreased expression of GAD2 protein CTD PMID:18198484 PMID:24521700 NCBI chr17:89,171,576...89,234,770
Ensembl chr17:89,171,250...89,238,040 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions
increases expression		 ISO
EXP		 GPX1 protein affects the reaction [Paraquat affects the expression of GADD45A mRNA]
Paraquat results in increased expression of GADD45A mRNA		 CTD PMID:12595580 PMID:12654481 PMID:15246999 PMID:17935786 PMID:18836921 PMID:19526292 PMID:20883675 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta increases expression ISO Paraquat results in increased expression of GADD45B mRNA CTD PMID:12595580 PMID:15246999 NCBI chr 7:11,646,283...11,648,338
Ensembl chr 7:11,646,269...11,648,322 		JBrowse link
G Gadd45g growth arrest and DNA-damage-inducible, gamma increases expression ISO Paraquat results in increased expression of GADD45G mRNA CTD PMID:12595580 PMID:15246999 NCBI chr17:13,391,474...13,393,219
Ensembl chr17:13,391,467...13,393,243 		JBrowse link
G Gak cyclin G associated kinase increases expression EXP Paraquat results in increased expression of GAK mRNA CTD PMID:18198484 NCBI chr14:2,100,104...2,174,332
Ensembl chr14:2,100,106...2,174,318 		JBrowse link
G Gap43 growth associated protein 43 increases expression EXP Paraquat results in increased expression of GAP43 mRNA CTD PMID:18198484 NCBI chr11:58,624,198...58,717,916
Ensembl chr11:58,624,198...58,717,914 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase multiple interactions
affects localization		 EXP [7-nitroindazole results in decreased chemical synthesis of Nitric Oxide] inhibits the reaction [Paraquat affects the localization of GAPDH protein]; Selegiline inhibits the reaction [Paraquat affects the localization of GAPDH protein] CTD PMID:20478973 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase increases expression
decreases expression		 ISO Paraquat results in increased expression of GART mRNA
Paraquat results in decreased expression of GART mRNA		 CTD PMID:21371552 NCBI chr11:31,780,477...31,805,728
Ensembl chr11:31,780,487...31,805,728 		JBrowse link
G Gas5 growth arrest specific 5 multiple interactions
decreases expression		 ISO [Paraquat co-treated with Maneb] results in decreased expression of GAS5 mRNA
Paraquat results in decreased expression of GAS5 mRNA		 CTD PMID:18386188 PMID:26824344 NCBI chr13:78,852,523...78,855,844 JBrowse link
G Gast gastrin increases expression EXP Paraquat results in increased expression of GAST mRNA CTD PMID:18198484 NCBI chr10:88,245,532...88,248,485
Ensembl chr10:88,245,532...88,248,484 		JBrowse link
G Gata3 GATA binding protein 3 decreases expression ISO Paraquat results in decreased expression of GATA3 CTD PMID:25496228 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681 		JBrowse link
G Gcgr glucagon receptor decreases expression EXP Paraquat results in decreased expression of GCGR mRNA CTD PMID:17077588 NCBI chr10:109,707,863...109,716,253
Ensembl chr10:109,707,962...109,716,128 		JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression EXP Paraquat results in increased expression of GCH1 mRNA CTD PMID:20388547 NCBI chr15:23,935,011...23,968,971
Ensembl chr15:23,934,585...23,969,011 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
decreases expression
affects expression		 ISO
EXP		 Paraquat results in increased expression of GCLC mRNA
SIRT6 promotes the reaction [Paraquat results in increased expression of GCLC mRNA]
Paraquat results in decreased expression of GCLC mRNA; Paraquat results in decreased expression of GCLC protein
[alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLC mRNA; Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of GCLC protein]; CAT protein inhibits the reaction [Paraquat results in decreased expression of GCLC protein]; meloxicam inhibits the reaction [Paraquat results in decreased expression of GCLC protein]
Paraquat affects the expression of GCLC mRNA		 CTD PMID:16854511 PMID:17215068 PMID:20851755 PMID:24530478 PMID:24866057 PMID:26598004 PMID:28467894 PMID:31216030 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases response to substance
increases expression
decreases expression
multiple interactions		 ISO
EXP		 GCLM gene mutant form results in increased susceptibility to Paraquat
Paraquat results in increased expression of GCLM mRNA
Paraquat results in decreased expression of GCLM protein
[alpha-Tocopherol co-treated with Paraquat] results in increased expression of GCLM mRNA
[GCLM gene mutant form results in increased susceptibility to Paraquat] which results in decreased abundance of Dopamine; [GCLM gene mutant form results in increased susceptibility to Paraquat] which results in decreased activity of ACO2 protein; SIRT6 promotes the reaction [Paraquat results in increased expression of GCLM mRNA]		 CTD PMID:23704229 PMID:24530478 PMID:27993944 PMID:28467894 PMID:31216030 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Paraquat results in increased expression of GDF15 mRNA CTD PMID:20883675 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978 		JBrowse link
G Gdf3 growth differentiation factor 3 increases expression
multiple interactions		 ISO Paraquat results in increased expression of GDF3 mRNA; Paraquat results in increased expression of GDF3 protein
Paraquat affects the reaction [Bucladesine affects the expression of GDF3 mRNA]; Paraquat affects the reaction [Bucladesine affects the expression of GDF3 protein]		 CTD PMID:30698896 PMID:31400064 NCBI chr 4:155,417,667...155,422,014
Ensembl chr 4:155,417,004...155,421,998 		JBrowse link
G Gdnf glial cell derived neurotrophic factor decreases response to substance
increases expression
multiple interactions		 ISO GDNF protein results in decreased susceptibility to Paraquat
Paraquat results in increased expression of GDNF mRNA
APOD protein affects the reaction [Paraquat results in increased expression of GDNF mRNA]		 CTD PMID:17935603 PMID:21688324 PMID:29454966 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
affects expression
increases expression		 ISO
EXP		 [Paraquat co-treated with Maneb] results in increased expression of GFAP protein; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of GFAP protein]; APOD protein affects the reaction [Paraquat results in increased expression of GFAP protein]
Paraquat affects the expression of GFAP mRNA
Paraquat results in increased expression of GFAP mRNA; Paraquat results in increased expression of GFAP protein
[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of GFAP protein		 CTD PMID:21688324 PMID:24376630 PMID:24521700 PMID:25314302 PMID:28467894 PMID:29454966 PMID:30280190 PMID:30698896 PMID:30797899 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 increases expression EXP Paraquat results in increased expression of GFRA1 mRNA CTD PMID:17077588 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Gfra2 GDNF family receptor alpha 2 increases expression EXP Paraquat results in increased expression of GFRA2 mRNA CTD PMID:18198484 NCBI chr15:52,557,004...52,648,984
Ensembl chr15:52,557,607...52,648,972 		JBrowse link
G Gh1 growth hormone 1 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of GH mRNA CTD PMID:22563483 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180 		JBrowse link
G Ghr growth hormone receptor increases response to substance
affects response to substance
decreases response to substance		 ISO GHR gene mutant form results in increased susceptibility to Paraquat
GHR protein affects the susceptibility to Paraquat
GHR gene mutant form results in decreased susceptibility to Paraquat		 CTD PMID:12384824 PMID:15701676 PMID:16713617 PMID:19786089 NCBI chr 2:53,149,225...53,413,954
Ensembl chr 2:53,150,370...53,413,638 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide multiple interactions ISO GHRL protein inhibits the reaction [Paraquat results in increased activity of CASP3 protein] CTD PMID:31381934 NCBI chr 4:145,674,157...145,678,066
Ensembl chr 4:145,674,157...145,678,066 		JBrowse link
G Ghsr growth hormone secretagogue receptor decreases expression EXP Paraquat results in decreased expression of GHSR mRNA CTD PMID:17077588 NCBI chr 2:113,065,953...113,071,265
Ensembl chr 2:113,066,885...113,070,261 		JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression ISO Paraquat results in decreased expression of GJA1 mRNA CTD PMID:12595580 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089 		JBrowse link
G Gjb1 gap junction protein, beta 1 decreases expression ISO Paraquat results in decreased expression of GJB1 mRNA CTD PMID:16797015 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977 		JBrowse link
G Glrx glutaredoxin increases response to substance
increases expression		 ISO GLRX gene mutant form results in increased susceptibility to Paraquat
Paraquat results in increased expression of GLRX mRNA		 CTD PMID:12732627 PMID:17893043 NCBI chr 2:2,606,032...2,615,944
Ensembl chr 2:2,605,996...2,615,944 		JBrowse link
G Glrx2 glutaredoxin 2 decreases expression
increases expression		 ISO Paraquat results in decreased expression of GLRX2 mRNA
Paraquat results in increased expression of GLRX2 mRNA		 CTD PMID:12732627 PMID:21371552 NCBI chr13:60,529,057...60,552,115
Ensembl chr13:60,529,932...60,537,916 		JBrowse link
G Gls glutaminase decreases activity EXP Paraquat results in decreased activity of GLS protein CTD PMID:28916328 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872 		JBrowse link
G Glul glutamate-ammonia ligase multiple interactions
affects expression
decreases expression
increases expression		 EXP
ISO		 [Paraquat results in increased abundance of Reactive Oxygen Species] which results in decreased expression of GLUL protein; SB 203580 inhibits the reaction [[Paraquat results in increased abundance of Reactive Oxygen Species] which results in decreased expression of GLUL protein]
Paraquat affects the expression of GLUL mRNA
Paraquat results in decreased expression of GLUL protein
Paraquat results in increased expression of GLUL protein		 CTD PMID:24376630 PMID:24521700 PMID:29454966 NCBI chr13:71,331,052...71,340,207
Ensembl chr13:71,331,052...71,340,229 		JBrowse link
G Gm2a GM2 ganglioside activator multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of GM2A mRNA CTD PMID:18386188 NCBI chr10:40,438,394...40,450,927
Ensembl chr10:40,438,356...40,450,930 		JBrowse link
G Gmfb glia maturation factor, beta multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of GMFB mRNA; [Paraquat co-treated with Maneb] results in decreased expression of GMFB protein CTD PMID:17532186 NCBI chr15:23,597,846...23,611,541
Ensembl chr15:23,601,368...23,606,634 		JBrowse link
G Gnai3 G protein subunit alpha i3 increases expression EXP Paraquat results in increased expression of GNAI3 mRNA CTD PMID:17077588 NCBI chr 2:210,896,779...210,934,733
Ensembl chr 2:210,896,656...210,934,749 		JBrowse link
G Gnao1 G protein subunit alpha o1 affects expression EXP Paraquat affects the expression of GNAO1 mRNA CTD PMID:15206577 NCBI chr19:11,513,201...11,669,578
Ensembl chr19:11,513,201...11,669,578 		JBrowse link
G Gnas GNAS complex locus increases expression
affects expression		 ISO
EXP		 Paraquat results in increased expression of GNAS mRNA
Paraquat affects the expression of GNAS mRNA		 CTD PMID:15206577 PMID:16797015 NCBI chr 3:172,374,957...172,434,988
Ensembl chr 3:172,374,957...172,428,483
Ensembl chr 3:172,374,957...172,428,483 		JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of GNG5 mRNA CTD PMID:18386188 NCBI chr 2:252,359,976...252,368,473
Ensembl chr 2:252,359,976...252,368,473 		JBrowse link
G Gngt2 G protein subunit gamma transducin 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of GNGT2 mRNA CTD PMID:22563483 NCBI chr10:83,654,321...83,658,601
Ensembl chr10:83,655,460...83,658,589 		JBrowse link
G Gnrhr gonadotropin releasing hormone receptor decreases expression EXP Paraquat results in decreased expression of GNRHR mRNA CTD PMID:17077588 NCBI chr14:23,480,462...23,498,450
Ensembl chr14:23,480,462...23,498,450 		JBrowse link
G Gopc golgi associated PDZ and coiled-coil motif containing increases expression ISO Paraquat results in increased expression of GOPC mRNA CTD PMID:21371552 NCBI chr20:33,471,355...33,521,281
Ensembl chr20:33,471,351...33,521,311 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 decreases activity
increases expression		 EXP Paraquat results in decreased activity of GOT1 protein
Paraquat results in increased expression of GOT1 mRNA		 CTD PMID:16555045 PMID:17481832 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 decreases expression ISO Paraquat results in decreased expression of GOT2 mRNA CTD PMID:21371552 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340 		JBrowse link
G Gpc1 glypican 1 affects expression EXP Paraquat affects the expression of GPC1 mRNA CTD PMID:15206577 NCBI chr 9:99,998,275...100,026,818
Ensembl chr 9:99,998,275...100,026,818 		JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 increases expression EXP Paraquat results in increased expression of GPER1 mRNA CTD PMID:17077588 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112 		JBrowse link
G Gpr27 G protein-coupled receptor 27 decreases expression
multiple interactions		 ISO Paraquat results in decreased expression of GPR27 mRNA
[Paraquat co-treated with Maneb] affects the expression of GPR27 mRNA		 CTD PMID:22563483 NCBI chr 4:132,137,793...132,138,926
Ensembl chr 4:132,137,793...132,138,926 		JBrowse link
G Gpr6 G protein-coupled receptor 6 increases expression EXP Paraquat results in increased expression of GPR6 mRNA CTD PMID:17077588 NCBI chr20:45,813,169...45,815,940
Ensembl chr20:45,813,169...45,815,940 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases activity		 ISO NME1 protein affects the reaction [Paraquat results in increased activity of GPT protein] CTD PMID:28077425 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression
affects expression
decreases expression
multiple interactions
decreases response to substance
increases response to substance		 ISO
EXP		 Paraquat results in increased expression of GPX1 mRNA
Paraquat affects the expression of GPX1 protein
Paraquat results in decreased expression of GPX1 mRNA
[Maneb co-treated with Paraquat] results in increased expression of GPX1 mRNA; [Paraquat results in increased abundance of Reactive Oxygen Species] which results in decreased expression of GPX1 mRNA; Estradiol affects the reaction [Paraquat affects the expression of GPX1 protein]
GPX1 protein results in decreased susceptibility to Paraquat
GPX1 protein affects the reaction [Paraquat affects the expression of BAX mRNA]; GPX1 protein affects the reaction [Paraquat affects the expression of BCL2 mRNA]; GPX1 protein affects the reaction [Paraquat affects the expression of BCL2L2 mRNA]; GPX1 protein affects the reaction [Paraquat affects the expression of GADD45A mRNA]; GPX1 protein affects the reaction [Paraquat affects the expression of MDM2 mRNA]; GPX1 protein affects the reaction [Paraquat affects the expression of MYC mRNA]; GPX1 protein affects the reaction [Paraquat results in increased activity of CASP3 protein]; GPX1 protein affects the reaction [Paraquat results in increased expression of BCL2L1 protein]; GPX1 protein affects the reaction [Paraquat results in increased expression of CASP3 protein]; pirfenidone inhibits the reaction [Paraquat results in decreased expression of GPX1 mRNA]; resolvin D1 analog inhibits the reaction [Paraquat results in decreased expression of GPX1 mRNA]; Sodium Selenite affects the reaction [GPX1 gene mutant form affects the susceptibility to Paraquat]
[Plant Extracts co-treated with Paraquat] results in increased expression of GPX1 mRNA; GPX1 protein results in decreased susceptibility to [Paraquat co-treated with Maneb]; Plant Extracts inhibits the reaction [Paraquat results in decreased expression of GPX1 mRNA]
GPX1 gene mutant form results in increased susceptibility to Paraquat		 CTD PMID:11568445 PMID:12595580 PMID:12654481 PMID:15182862 PMID:15824117 PMID:17935786 PMID:18686095 PMID:21371552 PMID:24141985 PMID:24376630 PMID:26108578 PMID:29273418 PMID:29287252 PMID:29859004 PMID:30243747 PMID:30562684 PMID:31715309 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522 		JBrowse link
G Gpx2 glutathione peroxidase 2 increases expression
multiple interactions
decreases expression
affects expression		 ISO Paraquat results in increased expression of GPX2 mRNA
[Paraquat co-treated with naringenin] results in increased expression of GPX2 mRNA
Paraquat results in decreased expression of GPX2 mRNA
APOD protein affects the reaction [Paraquat results in decreased expression of GPX2 mRNA]
Paraquat affects the expression of GPX2 mRNA		 CTD PMID:10806356 PMID:12732627 PMID:21688324 PMID:24561720 NCBI chr 6:99,839,960...99,843,245
Ensembl chr 6:99,839,960...99,843,245 		JBrowse link
G Gpx3 glutathione peroxidase 3 affects expression
multiple interactions
decreases expression
increases expression		 EXP
ISO		 Paraquat affects the expression of GPX3 mRNA
[Paraquat co-treated with naringenin] results in increased expression of GPX3 mRNA; [Paraquat co-treated with Thioctic Acid] results in increased expression of GPX3 mRNA
Paraquat results in decreased expression of GPX3 mRNA
Paraquat results in increased expression of GPX3 mRNA
APOD protein affects the reaction [Paraquat results in increased expression of GPX3 mRNA]		 CTD PMID:12732627 PMID:15206577 PMID:18198484 PMID:21688324 PMID:23649336 PMID:24561720 NCBI chr10:40,247,436...40,255,423
Ensembl chr10:40,247,436...40,255,422 		JBrowse link
G Gpx4 glutathione peroxidase 4 increases response to substance
multiple interactions
increases expression
decreases response to substance		 ISO GPX4 gene mutant form results in increased susceptibility to Paraquat
[Paraquat co-treated with Maneb] results in decreased expression of GPX4 protein
[Paraquat co-treated with Maneb] results in decreased expression of GPX4 protein; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of GPX4 protein]
Paraquat results in increased expression of GPX4 mRNA
GPX4 protein results in decreased susceptibility to Paraquat		 CTD PMID:12566075 PMID:12732627 PMID:30797899 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154 		JBrowse link
G Gpx5 glutathione peroxidase 5 increases expression
multiple interactions		 ISO Paraquat results in increased expression of GPX5 mRNA
[Paraquat co-treated with naringenin] results in increased expression of GPX5 mRNA; [Quercetin co-treated with Paraquat] results in increased expression of GPX5 mRNA		 CTD PMID:22996356 PMID:24561720 NCBI chr17:45,508,657...45,518,686
Ensembl chr17:45,467,015...45,518,686 		JBrowse link
G Gpx7 glutathione peroxidase 7 multiple interactions ISO [Paraquat co-treated with naringenin] results in increased expression of GPX7 mRNA CTD PMID:24561720 NCBI chr 5:128,001,766...128,009,610
Ensembl chr 5:128,001,761...128,009,735 		JBrowse link
G Grb2 growth factor receptor bound protein 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of GRB2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of GRB2 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of GRB2 mRNA] CTD PMID:23963992 NCBI chr10:104,193,953...104,263,071
Ensembl chr10:104,193,955...104,263,071 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression EXP Paraquat results in decreased expression of GRIA2 protein CTD PMID:24521700 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629 		JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 decreases expression EXP Paraquat results in decreased expression of GRIK3 mRNA CTD PMID:18198484 NCBI chr 5:143,500,441...143,715,546
Ensembl chr 5:143,500,441...143,715,546 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression
multiple interactions		 EXP Paraquat results in decreased expression of GRIN1 mRNA; Paraquat results in decreased expression of NMDAR1 protein
Estradiol inhibits the reaction [Paraquat results in decreased expression of NMDAR1 protein]		 CTD PMID:19146868 PMID:28916328 PMID:31715309 NCBI chr 3:2,507,745...2,534,664
Ensembl chr 3:2,506,896...2,534,663 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A increases expression ISO
EXP		 Paraquat results in increased expression of GRIN2A mRNA CTD PMID:18198484 PMID:22563483 NCBI chr10:5,707,806...6,123,568
Ensembl chr10:5,930,298...6,119,990 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B increases expression
affects expression		 ISO
EXP		 Paraquat results in increased expression of GRIN2B mRNA
Paraquat affects the expression of GRIN2B mRNA		 CTD PMID:15206577 PMID:22563483 NCBI chr 4:169,541,620...170,000,216
Ensembl chr 4:169,560,387...169,999,873 		JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression EXP Paraquat results in increased expression of GRIN2C mRNA CTD PMID:18198484 NCBI chr10:103,798,290...103,816,923
Ensembl chr10:103,798,291...103,816,287 		JBrowse link
G Grk2 G protein-coupled receptor kinase 2 decreases expression EXP Paraquat results in decreased expression of GRK2 protein CTD PMID:24521700 NCBI chr 1:219,536,220...219,544,329
Ensembl chr 1:219,536,220...219,544,328 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 affects expression EXP Paraquat affects the expression of GRM2 mRNA CTD PMID:15206577 NCBI chr 8:115,344,999...115,358,628
Ensembl chr 8:115,344,999...115,358,046 		JBrowse link
G Grm6 glutamate metabotropic receptor 6 increases expression EXP Paraquat results in increased expression of GRM6 mRNA CTD PMID:18198484 NCBI chr10:36,345,503...36,363,416
Ensembl chr10:36,345,939...36,360,665 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha affects expression
increases phosphorylation
decreases expression
multiple interactions		 EXP
ISO		 Paraquat affects the expression of GSK3A mRNA
Paraquat results in increased phosphorylation of GSK3A protein
Paraquat results in decreased expression of GSK3A protein
6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in decreased expression of GSK3A protein modified form]		 CTD PMID:15206577 PMID:28414160 PMID:30205152 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
decreases phosphorylation
increases phosphorylation
decreases expression		 ISO Lithium Chloride inhibits the reaction [Paraquat results in decreased phosphorylation of GSK3B protein]; Paraquat results in increased expression of and results in increased phosphorylation of GSK3B protein
Paraquat results in increased phosphorylation of GSK3B protein
6-bromoindirubin-3'-oxime promotes the reaction [Paraquat inhibits the reaction [TNFRSF10B protein binds to GSK3B protein]]; 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in decreased expression of GSK3B protein modified form]; Paraquat inhibits the reaction [TNFRSF10B protein binds to GSK3B protein]; WNT1 protein inhibits the reaction [Paraquat results in decreased phosphorylation of GSK3B protein]		 CTD PMID:22292029 PMID:24634145 PMID:28414160 PMID:30171970 PMID:30205152 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268 		JBrowse link
G Gsr glutathione-disulfide reductase decreases expression
decreases activity
affects expression
multiple interactions
increases expression		 ISO
EXP		 Paraquat results in decreased expression of GSR mRNA; Paraquat results in decreased expression of GSR protein
Paraquat results in decreased activity of GSR protein
Paraquat affects the expression of GSR protein
[Plant Extracts co-treated with Paraquat] results in increased expression of GSR mRNA; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Paraquat results in decreased activity of GSR protein]; Paraquat inhibits the reaction [naringenin results in increased expression of GSR mRNA]
[Acetylcysteine co-treated with Paraquat co-treated with Maneb] results in increased activity of GSR protein; [Acetylcysteine co-treated with Paraquat] results in increased activity of GSR protein; [Silymarin co-treated with Paraquat co-treated with Maneb] results in increased activity of GSR protein; [Silymarin co-treated with Paraquat] results in increased activity of GSR protein; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [Paraquat results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in decreased activity of GSR protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; EUK-134 inhibits the reaction [Paraquat results in decreased activity of GSR protein]; EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in decreased activity of GSR protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]; Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]
Paraquat results in increased expression of GSR mRNA
Dapsone inhibits the reaction [Paraquat results in decreased expression of GSR protein]; Dapsone inhibits the reaction [Paraquat results in increased expression of GSR mRNA]		 CTD PMID:10699569 PMID:12954614 PMID:15754033 PMID:16797015 PMID:17215068 PMID:20553223 PMID:21765237 PMID:23159886 PMID:24141985 PMID:24561720 PMID:25724285 PMID:28467894 PMID:30185695 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361 		JBrowse link
G Gss glutathione synthetase multiple interactions
increases expression		 ISO SIRT6 promotes the reaction [Paraquat results in increased expression of GSS mRNA] CTD PMID:31216030 NCBI chr 3:151,076,254...151,106,557
Ensembl chr 3:151,076,254...151,106,557 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP
ISO		 Paraquat results in increased expression of GSTA2 mRNA; Paraquat results in increased expression of GSTA3 mRNA
Paraquat results in increased expression of GSTA1 mRNA		 CTD PMID:16128001 PMID:16328009 PMID:20888808 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta3 glutathione S-transferase alpha 3 decreases expression
increases expression		 ISO Paraquat results in decreased expression of GSTA3 mRNA
Paraquat results in increased expression of GSTA2 mRNA; Paraquat results in increased expression of GSTA3 mRNA		 CTD PMID:12595580 PMID:16128001 PMID:17215068 PMID:18620719 NCBI chr 9:27,357,490...27,417,023
Ensembl chr 9:27,402,381...27,417,023 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 multiple interactions
increases expression
increases activity		 EXP [Acetylcysteine co-treated with EUK-134] promotes the reaction [[Zinc Sulfate co-treated with Paraquat] results in increased activity of GSTA4 protein]; [EUK-134 co-treated with Acetylcysteine] promotes the reaction [Paraquat results in increased activity of GSTA4 protein]; [Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of GSTA4 protein; [Paraquat co-treated with Maneb] results in increased expression of GSTA4 mRNA; [Zinc Sulfate co-treated with Paraquat] results in increased activity of GSTA4 protein; Acetylcysteine promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of GSTA4 mRNA]; Acetylcysteine promotes the reaction [Paraquat results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [Paraquat results in increased expression of GSTA4 mRNA]; Paraquat promotes the reaction [Zinc Sulfate results in increased expression of GSTA4 mRNA]; Paraquat results in increased expression of and results in increased activity of GSTA4 protein; Silymarin promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of GSTA4 protein]; Silymarin promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of GSTA4 mRNA]; Silymarin promotes the reaction [Paraquat results in increased expression of and results in increased activity of GSTA4 protein]; Silymarin promotes the reaction [Paraquat results in increased expression of GSTA4 mRNA]; Zinc Sulfate promotes the reaction [Paraquat results in increased expression of GSTA4 mRNA]
Paraquat results in increased expression of GSTA4 mRNA; Paraquat results in increased expression of GSTA4 protein		 CTD PMID:20553223 PMID:20888808 PMID:23159886 PMID:24521700 PMID:25724285 NCBI chr 8:85,497,557...85,514,732
Ensembl chr 8:85,497,557...85,518,879 		JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression ISO Paraquat results in increased expression of GSTA1 mRNA CTD PMID:16128001 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO Paraquat results in increased expression of GSTM1 mRNA CTD PMID:16128001 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression
decreases expression		 EXP
ISO		 Paraquat results in increased expression of GSTM2 mRNA
Paraquat results in decreased expression of GSTM2 mRNA		 CTD PMID:16128001 PMID:16555045 PMID:17935786 PMID:21371552 NCBI chr 2:210,778,041...210,782,807
Ensembl chr 2:210,720,704...210,782,856 		JBrowse link
G Gstm3 glutathione S-transferase mu 3 increases expression ISO Paraquat results in increased expression of GSTM3 mRNA CTD PMID:20883675 NCBI chr 2:210,685,204...210,688,273
Ensembl chr 2:210,685,197...210,688,272 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 increases expression
affects expression		 ISO Paraquat results in increased expression of GSTM3 mRNA
Paraquat affects the expression of GSTM5 mRNA		 CTD PMID:16128001 PMID:20883675 PMID:27788593 NCBI chr 2:210,685,338...210,688,133
Ensembl chr 2:210,685,197...210,688,272 		JBrowse link
G Gsto1 glutathione S-transferase omega 1 increases expression ISO Paraquat results in increased expression of GSTO1 mRNA CTD PMID:16128001 NCBI chr 1:267,607,437...267,617,387
Ensembl chr 1:267,607,418...267,617,387 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases expression
increases expression
multiple interactions		 ISO Paraquat results in decreased expression of GSTP1 protein
Paraquat results in increased expression of GSTP1 mRNA
[Maneb co-treated with Paraquat] results in decreased expression of GSTP1 mRNA; Dapsone inhibits the reaction [Paraquat results in decreased expression of GSTP1 protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of GSTP1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of GSTP1 mRNA]		 CTD PMID:16128001 PMID:18620719 PMID:21765237 PMID:23963992 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147 		JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects response to substance ISO GSTT1 protein affects the susceptibility to Paraquat CTD PMID:23045187 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526 		JBrowse link
G Gstt2 glutathione S-transferase, theta 2 increases expression EXP Paraquat results in increased expression of GSTT2 protein CTD PMID:24521700 NCBI chr20:13,760,810...13,764,481
Ensembl chr20:13,760,810...13,764,475 		JBrowse link
G Gstz1 glutathione S-transferase zeta 1 increases expression
multiple interactions		 ISO Paraquat results in increased expression of GSTZ1 mRNA
[Paraquat co-treated with Quercetin] results in increased expression of GSTZ1 mRNA; Paraquat inhibits the reaction [naringenin results in increased expression of GSTZ1 mRNA]		 CTD PMID:22996356 PMID:24561720 NCBI chr 6:111,176,798...111,187,246
Ensembl chr 6:111,176,798...111,187,244 		JBrowse link
G Gtpbp1 GTP binding protein 1 decreases expression ISO Paraquat results in decreased expression of GTPBP1 mRNA CTD PMID:21371552 NCBI chr 7:120,923,274...120,947,723
Ensembl chr 7:120,923,274...120,947,723 		JBrowse link
G Gucy1a1 guanylate cyclase 1 soluble subunit alpha 1 increases expression EXP Paraquat results in increased expression of GUCY1A1 mRNA CTD PMID:20388547 NCBI chr 2:181,045,694...181,103,321
Ensembl chr 2:181,045,703...181,102,918 		JBrowse link
G Guk1 guanylate kinase 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of GUK1 mRNA CTD PMID:18386188 NCBI chr10:45,535,617...45,552,455
Ensembl chr10:45,535,627...45,543,897 		JBrowse link
G H2ac20 H2A clustered histone 20 decreases expression
multiple interactions		 ISO Paraquat results in decreased expression of H2AC20 mRNA
[Paraquat co-treated with Maneb] affects the expression of H2AC20 mRNA		 CTD PMID:22563483 NCBI chr 2:198,360,271...198,360,735
Ensembl chr 2:198,360,301...198,360,678 		JBrowse link
G H2ax H2A.X variant histone multiple interactions
increases expression		 ISO ATG7 protein affects the reaction [Paraquat results in increased expression of H2AX protein] CTD PMID:28012437 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981 		JBrowse link
G H2bu1 H2B.U histone 1 decreases expression
multiple interactions		 ISO Paraquat results in decreased expression of H2BC9 mRNA
[Paraquat co-treated with Maneb] affects the expression of H2BC9 mRNA		 CTD PMID:22563483 NCBI chr10:45,296,638...45,297,385
Ensembl chr10:45,296,638...45,297,385 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO [ABCB1A gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of HAVCR1 mRNA; [ABCB1B gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of HAVCR1 mRNA; [SLC47A1 gene mutant form results in increased susceptibility to Paraquat] which results in increased expression of HAVCR1 mRNA CTD PMID:21991918 PMID:25015657 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379 		JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of HBA-A1 mRNA CTD PMID:18386188 NCBI chr10:15,602,794...15,603,649
Ensembl chr10:15,602,794...15,603,649 		JBrowse link
G Hbb hemoglobin subunit beta decreases expression ISO Paraquat results in decreased expression of HBB-B1 mRNA CTD PMID:21371552 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725 		JBrowse link
G Hdac4 histone deacetylase 4 decreases expression EXP Paraquat results in decreased expression of HDAC4 protein CTD PMID:21777615 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715 		JBrowse link
G Hdac7 histone deacetylase 7 decreases expression EXP Paraquat results in decreased expression of HDAC7 protein CTD PMID:21777615 NCBI chr 7:139,280,396...139,319,108
Ensembl chr 7:139,281,187...139,318,455 		JBrowse link
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 increases expression ISO Paraquat results in increased expression of HERPUD1 mRNA CTD PMID:12595580 NCBI chr19:11,046,905...11,057,440
Ensembl chr19:11,046,909...11,057,254 		JBrowse link
G Hes3 hes family bHLH transcription factor 3 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of HES3 mRNA CTD PMID:22563483 NCBI chr 5:169,463,196...169,469,795
Ensembl chr 5:169,464,989...169,467,153 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of HEY2 mRNA CTD PMID:23017109 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of HEYL mRNA CTD PMID:23017109 NCBI chr 5:140,923,914...140,940,905
Ensembl chr 5:140,923,914...140,940,905 		JBrowse link
G Hfe homeostatic iron regulator affects response to substance
multiple interactions		 ISO HFE protein alternative form affects the susceptibility to Paraquat
[HFE protein alternative form affects the susceptibility to Paraquat] which affects the expression of NFE2L2; HFE protein alternative form affects the reaction [Paraquat results in decreased expression of TOMM20 protein]; HFE protein alternative form affects the reaction [Paraquat results in increased expression of NFE2L2 protein]; NFE2L2 protein affects the reaction [HFE protein alternative form affects the susceptibility to Paraquat]		 CTD PMID:32540480 NCBI chr17:43,661,276...43,669,327
Ensembl chr17:43,661,222...43,669,985 		JBrowse link
G Hgf hepatocyte growth factor increases expression ISO Paraquat results in increased expression of HGF mRNA CTD PMID:16324872 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha increases expression
multiple interactions		 ISO
EXP		 Paraquat results in increased expression of HIF1A protein
Paraquat results in increased expression of HIF1A mRNA; Paraquat results in increased expression of HIF1A protein
HIF1A protein affects the reaction [Paraquat results in decreased expression of TJP1 protein]; HIF1A protein affects the reaction [Paraquat results in increased expression of ACTA2 protein]		 CTD PMID:26781174 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Hist3h2a histone cluster 3, H2a multiple interactions
decreases expression		 ISO [Paraquat co-treated with Maneb] affects the expression of H2AC6 mRNA
Paraquat results in decreased expression of H2AC6 mRNA		 CTD PMID:22563483 NCBI chr10:45,297,603...45,299,155 JBrowse link
G Hk1 hexokinase 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of HK1 mRNA CTD PMID:18386188 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649 		JBrowse link
G Hm13 histocompatibility minor 13 decreases expression ISO Paraquat results in decreased expression of H13 mRNA CTD PMID:21371552 NCBI chr 3:148,150,695...148,189,623
Ensembl chr 3:148,150,698...148,189,623 		JBrowse link
G Hmga2 high mobility group AT-hook 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of HMGA2 mRNA CTD PMID:18386188 NCBI chr 7:65,159,944...65,275,408
Ensembl chr 7:65,159,944...65,275,408 		JBrowse link
G Hmgb1 high mobility group box 1 increases expression
multiple interactions		 EXP Paraquat results in increased expression of HMGB1 mRNA
Febuxostat inhibits the reaction [Paraquat results in increased expression of HMGB1 mRNA]		 CTD PMID:19497220 PMID:30726711 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237 		JBrowse link
G Hmgcl 3-hydroxy-3-methylglutaryl-CoA lyase decreases expression EXP
ISO		 Paraquat results in decreased expression of HMGCL mRNA CTD PMID:17077588 PMID:21371552 NCBI chr 5:154,294,841...154,308,582
Ensembl chr 5:154,294,806...154,308,640 		JBrowse link
G Hmgn5 high mobility group nucleosome binding domain 5 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of HMGN5 mRNA CTD PMID:22563483 NCBI chr  X:80,134,557...80,142,902
Ensembl chr  X:80,134,557...80,142,902 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
affects expression
affects activity
increases activity
decreases expression
increases expression		 EXP
ISO		 [Mifepristone co-treated with Paraquat] results in increased expression of HMOX1 mRNA; [Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of HMOX1 mRNA; alpha-Tocopherol inhibits the reaction [Paraquat results in increased activity of HMOX1 protein]; Curcumin inhibits the reaction [Paraquat results in increased activity of HMOX1 protein]; Estradiol affects the reaction [Paraquat affects the expression of HMOX1 protein]; Hemin promotes the reaction [Paraquat results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [[Mifepristone co-treated with Paraquat] results in increased expression of HMOX1 mRNA]; Quercetin inhibits the reaction [Paraquat results in increased expression of HMOX1]; SB 203580 promotes the reaction [[Paraquat results in increased abundance of Reactive Oxygen Species] which results in increased expression of HMOX1 mRNA]
Paraquat affects the expression of HMOX1 mRNA
Paraquat affects the activity of HMOX1 protein
Paraquat results in decreased expression of HMOX1 mRNA; Paraquat results in decreased expression of HMOX1 protein
Paraquat results in increased expression of HMOX1 mRNA; Paraquat results in increased expression of HMOX1 protein
Paraquat results in increased expression of HMOX1; Paraquat results in increased expression of HMOX1 mRNA; Paraquat results in increased expression of HMOX1 protein
2-tert-butylhydroquinone inhibits the reaction [Paraquat results in increased expression of HMOX1 protein]; [SIRT6 protein mutant form results in decreased activity of SIRT6 protein] inhibits the reaction [Paraquat promotes the reaction [SMARCA4 protein binds to HMOX1 enhancer]]; [SIRT6 protein mutant form results in decreased activity of SIRT6 protein] inhibits the reaction [Paraquat results in increased expression of HMOX1 mRNA]; naringin inhibits the reaction [Paraquat results in decreased expression of HMOX1 mRNA]; naringin inhibits the reaction [Paraquat results in decreased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [Paraquat results in increased expression of HMOX1 protein]; Paraquat affects the reaction [APOD protein affects the expression of HMOX1 protein]; Paraquat promotes the reaction [POLR2A protein modified form binds to HMOX1 gene]; Paraquat promotes the reaction [SIRT6 protein binds to HMOX1 gene]; Paraquat promotes the reaction [SMARCA4 protein binds to HMOX1 enhancer]; Paraquat promotes the reaction [SMARCC2 protein binds to HMOX1 enhancer]; plant extract, Puerariae Radix inhibits the reaction [Paraquat results in decreased expression of HMOX1 protein]; resolvin D1 analog inhibits the reaction [Paraquat results in decreased expression of HMOX1 mRNA]; resolvin D1 inhibits the reaction [Paraquat results in decreased expression of HMOX1 mRNA]; Resveratrol promotes the reaction [Paraquat results in increased activity of HMOX1 protein]; SIRT1 protein affects the reaction [Paraquat affects the activity of HMOX1 protein]; SIRT6 promotes the reaction [Paraquat results in increased expression of HMOX1 mRNA]; SIRT6 protein promotes the reaction [Paraquat promotes the reaction [POLR2A protein modified form binds to HMOX1 gene]]; SIRT6 protein promotes the reaction [Paraquat promotes the reaction [SMARCA4 protein binds to HMOX1 enhancer]]; SIRT6 protein promotes the reaction [Paraquat promotes the reaction [SMARCC2 protein binds to HMOX1 enhancer]]; SMARCC2 protein mutant form inhibits the reaction [Paraquat results in increased expression of HMOX1 mRNA]; SMARCC2 protein promotes the reaction [Paraquat results in increased expression of HMOX1 mRNA]
[Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Ellagic Acid] results in increased expression of HMOX1 protein; [Paraquat co-treated with naringenin] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Quercetin] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Thioctic Acid] results in increased expression of HMOX1 mRNA; [Paraquat co-treated with Thioctic Acid] results in increased expression of HMOX1 protein; [Quercetin co-treated with Paraquat] results in increased expression of HMOX1 protein; [SIRT6 protein results in decreased susceptibility to Paraquat] inhibits the reaction [NFE2L2 protein binds to HMOX1 enhancer]; [SNCA protein co-treated with Paraquat co-treated with Dopamine] results in increased expression of HMOX1 protein; NFE2L2 mRNA promotes the reaction [Paraquat promotes the reaction [SIRT6 protein binds to HMOX1 gene]]; Paraquat promotes the reaction [SIRT6 protein binds to HMOX1 gene]; Resveratrol promotes the reaction [Paraquat results in increased expression of HMOX1 mRNA]; Silymarin promotes the reaction [Paraquat results in increased expression of HMOX1 mRNA]; Silymarin promotes the reaction [Paraquat results in increased expression of HMOX1 protein]
Paraquat affects the expression of HMOX1 mRNA; Paraquat affects the expression of HMOX1 protein		 CTD PMID:11181820 PMID:12180188 PMID:15527874 PMID:15728566 PMID:16263688 PMID:16328009 PMID:16555045 PMID:16854511 PMID:17215068 PMID:17409708 PMID:17935786 PMID:18620719 PMID:19080378 PMID:20095327 PMID:20600150 PMID:21688324 PMID:21735318 PMID:22493042 PMID:22709784 PMID:22983789 PMID:22996356 PMID:23546295 PMID:23603004 PMID:23649336 PMID:24376630 PMID:24521700 PMID:24561720 PMID:24812154 PMID:25169090 PMID:26598004 PMID:26649146 PMID:26708779 PMID:26758514 PMID:26935021 PMID:27788593 PMID:28467894 PMID:29950142 PMID:30562684 PMID:30571954 PMID:31216030 PMID:31715309 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Hmox2 heme oxygenase 2 increases expression EXP Paraquat results in increased expression of HMOX2 mRNA CTD PMID:17935786 NCBI chr10:10,990,034...11,035,493
Ensembl chr10:10,990,034...11,035,484 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 increases expression
decreases expression		 ISO Paraquat results in increased expression of HNRNPA2B1 mRNA alternative form
Paraquat results in decreased expression of HNRNPA2B1 protein		 CTD PMID:17064354 PMID:27111068 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C multiple interactions ISO [HNRNPC protein binds to HNRNPC protein alternative form] which results in decreased susceptibility to Paraquat CTD PMID:16960656 NCBI chr15:28,486,605...28,517,353
Ensembl chr15:28,486,617...28,517,353 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D increases expression ISO Paraquat results in increased expression of HNRNPD mRNA alternative form CTD PMID:17064354 NCBI chr14:11,256,163...11,274,684
Ensembl chr14:11,256,268...11,274,578 		JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 decreases expression ISO Paraquat results in decreased expression of HNRNPH1 mRNA; Paraquat results in decreased expression of HNRNPH1 protein CTD PMID:27111068 NCBI chr10:35,872,619...35,879,911
Ensembl chr10:35,870,232...35,879,910 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K multiple interactions
increases expression		 ISO
EXP		 [Paraquat co-treated with Maneb] results in decreased expression of HNRNPK mRNA
Paraquat results in increased expression of HNRNPK mRNA		 CTD PMID:16328009 PMID:18386188 NCBI chr17:6,664,730...6,676,753
Ensembl chr17:6,665,659...6,676,654 		JBrowse link
G Homer2 homer scaffold protein 2 decreases expression ISO Paraquat results in decreased expression of HOMER2 mRNA CTD PMID:21371552 NCBI chr 1:143,443,300...143,535,579
Ensembl chr 1:143,443,300...143,535,583 		JBrowse link
G Hoxa3 homeobox A3 decreases expression ISO Paraquat results in decreased expression of HOXA3 mRNA CTD PMID:26824344 NCBI chr 4:82,137,802...82,181,836
Ensembl chr 4:82,138,683...82,141,385 		JBrowse link
G Hoxb13 homeo box B13 increases response to substance ISO HOXB13 protein results in increased susceptibility to Paraquat CTD PMID:24213000 NCBI chr10:84,031,955...84,034,228
Ensembl chr10:84,031,955...84,034,228 		JBrowse link
G Hpcal1 hippocalcin-like 1 increases expression ISO Paraquat results in increased expression of HPCAL1 mRNA CTD PMID:12595580 NCBI chr 6:43,001,920...43,109,083
Ensembl chr 6:43,001,948...43,109,071 		JBrowse link
G Hpn hepsin decreases expression ISO Paraquat results in decreased expression of HPN mRNA CTD PMID:16797015 NCBI chr 1:89,534,112...89,549,575
Ensembl chr 1:89,534,106...89,543,967 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO Paraquat results in increased expression of HPRT1 mRNA CTD PMID:21371552 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749 		JBrowse link
G Hras HRas proto-oncogene, GTPase affects splicing ISO Paraquat affects the splicing of HRAS mRNA CTD PMID:23613995 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686 		JBrowse link
G Hrk harakiri, BCL2 interacting protein decreases expression ISO Paraquat results in decreased expression of HRK mRNA CTD PMID:18836921 NCBI chr12:44,008,879...44,029,211 JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression
decreases expression		 EXP Paraquat results in increased expression of HSD11B1 mRNA
Paraquat results in decreased expression of HSD11B1 mRNA; Paraquat results in decreased expression of HSD11B1 protein		 CTD PMID:18198484 PMID:31128353 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603 		JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 decreases expression
increases expression		 ISO Paraquat results in decreased expression of HSD17B12 mRNA
Paraquat results in increased expression of HSD17B12 mRNA		 CTD PMID:21371552 NCBI chr 3:82,924,699...83,048,465
Ensembl chr 3:82,924,687...83,048,435 		JBrowse link
G Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 decreases expression EXP Paraquat results in decreased expression of HSD17B3 mRNA; Paraquat results in decreased expression of HSD17B3 protein CTD PMID:31128353 PMID:31610511 NCBI chr17:1,579,319...1,610,745
Ensembl chr17:1,579,319...1,610,745 		JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 increases expression EXP Paraquat results in increased expression of HSD3B1 mRNA; Paraquat results in increased expression of HSD3B1 protein CTD PMID:31128353
G Hsf1 heat shock transcription factor 1 multiple interactions
increases expression		 ISO [Maneb co-treated with Paraquat] results in decreased expression of HSF1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of HSF1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of HSF1 mRNA]; SIRT6 promotes the reaction [Paraquat results in increased expression of HSF1 mRNA]; SMARCC2 protein promotes the reaction [Paraquat results in increased expression of HSF1 mRNA] CTD PMID:23963992 PMID:31216030 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of HSP90AA1 mRNA; [Paraquat co-treated with Maneb] results in increased expression of HSP90AA1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of HSP90AA1 mRNA] CTD PMID:18386188 PMID:23963992 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases expression EXP Paraquat results in increased expression of HSP90B1 mRNA CTD PMID:17935786 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO Paraquat results in decreased expression of HSPA1A mRNA CTD PMID:20883675 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of HSPA1B mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of HSPA1B mRNA] CTD PMID:23963992 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like decreases response to substance ISO HSPA1L protein results in decreased susceptibility to Paraquat CTD PMID:24887138 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 decreases expression ISO Paraquat results in decreased expression of HSPA2 mRNA CTD PMID:20883675 NCBI chr 6:99,433,575...99,436,288
Ensembl chr 6:99,433,550...99,436,289 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions		 ISO
EXP		 Paraquat results in increased expression of HSPA5 mRNA; Paraquat results in increased expression of HSPA5 protein
[Paraquat co-treated with Maneb] results in increased expression of HSPA5 mRNA
Minocycline inhibits the reaction [Paraquat results in increased expression of HSPA5 protein]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of HSPA5 mRNA]; NFE2L2 mutant form inhibits the reaction [Paraquat results in increased expression of HSPA5 protein]
EIF2S1 protein promotes the reaction [salubrinal inhibits the reaction [Paraquat results in increased expression of HSPA5 protein]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [Paraquat results in increased expression of HSPA5 protein]; salubrinal inhibits the reaction [Paraquat results in increased expression of HSPA5 protein]		 CTD PMID:17935786 PMID:18198484 PMID:18386188 PMID:19735704 PMID:20883675 PMID:22245251 PMID:22678742 PMID:24912635 PMID:27442881 PMID:28986289 PMID:30185695 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of HSPA8 mRNA CTD PMID:18386188 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression EXP Paraquat results in increased expression of HSPA9 mRNA CTD PMID:17935786 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 affects expression
decreases expression		 EXP
ISO		 Paraquat affects the expression of HSPB1 mRNA
Paraquat results in decreased expression of HSPB1 mRNA		 CTD PMID:15206577 PMID:20883675 PMID:21371552 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression
multiple interactions
decreases expression		 EXP
ISO		 Paraquat results in increased expression of HSPD1 protein
HSPD1 protein promotes the reaction [Paraquat results in increased expression of IL1B mRNA]; HSPD1 protein promotes the reaction [Paraquat results in increased expression of IL6 mRNA]; HSPD1 protein promotes the reaction [Paraquat results in increased expression of MYD88 protein]; HSPD1 protein promotes the reaction [Paraquat results in increased expression of NOS2 mRNA]; HSPD1 protein promotes the reaction [Paraquat results in increased expression of TLR4 protein]; HSPD1 protein promotes the reaction [Paraquat results in increased expression of TNF mRNA]
Paraquat results in decreased expression of HSPD1 protein
Paraquat results in increased expression of HSPD1 mRNA		 CTD PMID:11746186 PMID:20883675 PMID:27788593 PMID:29441825 PMID:30584891 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP
ISO		 Paraquat results in increased expression of HSPE1 mRNA CTD PMID:17935786 PMID:20883675 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B decreases expression EXP Paraquat results in decreased expression of HTR1B mRNA CTD PMID:18198484 NCBI chr 8:89,113,984...89,130,830
Ensembl chr 8:89,129,453...89,130,991