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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2199
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bcl2
Name: BCL2, apoptosis regulator
Acc ID: CHEBI:27086
Term: tributylstannane
Definition: An organotin compound that has formula C12H28Sn.
Chemical ID: MESH:C011559
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcl2decreases expressionEXP 6480464CTDtributyltin results in decreased expression of BCL2 proteinPMID:23743147 PMID:26079211 PMID:28707438
Bcl2multiple interactionsEXP 6480464CTDAcetylcysteine inhibits the reaction [tributyltin results in decreased expression of BCL2 protein]PMID:26079211
Bcl2affects expressionISOBcl2 (Mus musculus)6480464CTDtributyltin affects the expression of BCL2 proteinPMID:22223438
Bcl2decreases expressionISOBcl2 (Mus musculus)6480464CTDtributyltin results in decreased expression of BCL2 proteinPMID:33720505
Bcl2decreases expressionISOBCL2 (Homo sapiens)6480464CTDtributyltin results in decreased expression of BCL2 proteinPMID:25743928
Bcl2multiple interactionsISOBcl2 (Mus musculus)6480464CTDPRKCD gene mutant form inhibits the reaction [tributyltin results in decreased expression of BCL2 protein]PMID:25895139
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