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GENE - TERM ANNOTATION REPORT

RGD ID: 14098222
Species: Sus scrofa
RGD Object: Gene
Symbol: IL6
Name: interleukin 6
Acc ID: DOID:9002457
Term: Experimental Arthritis
Definition: ARTHRITIS that is induced in experimental animals. Immunological methods and infectious agents can be used to develop experimental arthritis models. These methods include injections of stimulators of the immune response, such as an adjuvant (ADJUVANTS, IMMUNOLOGIC) or COLLAGEN.
Definition Source(s): MESH:D001169
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL6treatmentISOIl6 (Mus musculus)9068941RGD PMID:10381487 REF_RGD_ID:11049553
IL6treatmentISOIl6 (Rattus norvegicus)9068941RGD PMID:23503893 PMID:24028507 PMID:8607900 REF_RGD_ID:10755447 REF_RGD_ID:11049551 REF_RGD_ID:11060267
IL6 ISOIL6 (Homo sapiens)9068941CTDCTD Direct Evidence: marker/mechanismPMID:20131233 PMID:20974942 PMID:22450443
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